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ONTOLOGY REPORT - ANNOTATIONS

Term:type III hypersensitivity
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Accession:GO:0001802 term browser browse the term
Definition:An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue.
Comment:Note that the Arthus reaction is an example of type III hypersensitivity.
Synonyms:xref: Wikipedia:Type_III_hypersensitivity


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positive regulation of type III hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562 		JBrowse link
G FCER1G Fc epsilon receptor Ig acts_upstream_of_or_within ISO (PMID:8976192) MGI PMID:8976192 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940 		JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia acts_upstream_of_or_within ISO (PMID:11911823) MGI PMID:11911823 NCBI chr17:59,073,139...59,102,023
Ensembl chr17:59,092,933...59,102,015 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    immune system process 2491
      immune effector process 650
        leukocyte mediated immunity 400
          myeloid leukocyte mediated immunity 123
            type III hypersensitivity 3
              negative regulation of type III hypersensitivity 0
              positive regulation of type III hypersensitivity 3
              regulation of type III hypersensitivity + 3
Path 2
Term Annotations click to browse term
  biological_process 17878
    response to stimulus 9437
      response to stress 4062
        defense response 1746
          inflammatory response 818
            inflammatory response to antigenic stimulus 88
              acute inflammatory response to antigenic stimulus 35
                hypersensitivity 16
                  type III hypersensitivity 3
                    negative regulation of type III hypersensitivity 0
                    positive regulation of type III hypersensitivity 3
                    regulation of type III hypersensitivity + 3
paths to the root