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ONTOLOGY REPORT - ANNOTATIONS


Term:B cell apoptotic process
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Accession:GO:0001783 term browser browse the term
Definition:Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
Synonyms:exact_synonym: B lymphocyte apoptosis;   B lymphocyte programmed cell death by apoptosis;   B-cell programmed cell death by apoptosis;   apoptosis of B cells;   apoptosis of B lymphocytes;   programmed cell death of B-cells by apoptosis;   programmed cell death of B-lymphocytes by apoptosis;   programmed cell death, B cells;   programmed cell death, B lymphocytes
 narrow_synonym: B cell apoptosis



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B cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within ISO MGI:99702 (MGI:3588597|PMID:16055554) RGD PMID:16055554 MGI:3588597 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1097161 (MGI:3588597|PMID:16055554)
(PMID:15214043), (PMID:16424160)
UniProt
RGD
PMID:15214043 PMID:16055554 PMID:16424160 GO_REF:0000024 MGI:3588597 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl10 BCL10, immune signaling adaptor acts_upstream_of_or_within
NOT|acts_upstream_of_or_within
ISO (MGI:1355482|PMID:10753917)
MGI:2158304 (MGI:1930354|PMID:11163238)
RGD PMID:10753917 PMID:11163238 MGI:1355482 MGI:1930354 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:4435697 (MGI:6150543|PMID:29581031) RGD PMID:29581031 MGI:6150543 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Mir17 microRNA 17 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3629917|MGI:3629918 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir18a microRNA 18a acts_upstream_of_or_within ISO MGI:2676872|MGI:3618743|MGI:3619065|MGI:3629917|MGI:3629918 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
JBrowse link
G Mir19a microRNA 19a acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3619065|MGI:3629917|MGI:3629918 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
JBrowse link
G Mir20a microRNA 20a acts_upstream_of_or_within ISO MGI:2676844|MGI:3618743|MGI:3619065|MGI:3629917|MGI:3629918 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:1931143 (MGI:3692035|PMID:12970677) RGD PMID:12970677 MGI:3692035 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Pkn1 protein kinase N1 acts_upstream_of_or_within ISO MGI:5475202 (MGI:5467878|PMID:23223530) RGD PMID:23223530 MGI:5467878 NCBI chr19:24,442,130...24,470,107
Ensembl chr19:24,442,122...24,470,107
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISS
ISO
GO_REF:0000024
(MGI:3628730|PMID:12515813)
UniProt
RGD
PMID:12515813 GO_REF:0000024 MGI:3628730 NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085
JBrowse link
G Traf3ip2 Traf3 interacting protein 2 acts_upstream_of_or_within ISO MGI:3510784 (MGI:3510272|PMID:15485634) RGD PMID:15485634 MGI:3510272 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667
JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in ISO
IEA
(PMID:15214043)
GO_REF:0000107
RGD
Ensembl
PMID:15214043 GO_REF:0000107 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
negative regulation of B cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISO
ISS
(PMID:20959462)
GO_REF:0000024
RGD
UniProt
PMID:20959462 GO_REF:0000024 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:25267198) RGD PMID:25267198 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Hsh2d hematopoietic SH2 domain containing acts_upstream_of_or_within ISO (MGI:3574118|PMID:15569688) RGD PMID:15569688 MGI:3574118 NCBI chr16:17,630,519...17,649,932
Ensembl chr16:17,635,322...17,647,991
JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:9184696) RGD PMID:9184696 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Irs2 insulin receptor substrate 2 involved_in ISO (MGI:4456946|PMID:15572028) RGD PMID:15572028 MGI:4456946 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Mir106a microRNA 106a acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr  X:132,422,584...132,422,661
Ensembl chr  X:132,422,584...132,422,661
JBrowse link
G Mir106b microRNA 106b acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425
JBrowse link
G Mir19b1 microRNA 19b-1 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3619439|MGI:3629918|MGI:3718454 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300
JBrowse link
G Mir19b2 microRNA 19b-2 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr  X:132,422,072...132,422,167
Ensembl chr  X:132,422,072...132,422,167
JBrowse link
G Mir20b microRNA 20b acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr  X:132,422,211...132,422,282
Ensembl chr  X:132,422,211...132,422,282
JBrowse link
G Mir25 microRNA 25 acts_upstream_of_or_within ISO (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015
JBrowse link
G Mir363 microRNA 363 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619438|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr  X:132,421,791...132,421,877
Ensembl chr  X:132,421,791...132,421,877
JBrowse link
G Mir92a1 microRNA 92a-1 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3619065|MGI:3629917 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413
JBrowse link
G Mir92a2 microRNA 92a-2 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr  X:132,421,942...132,422,033
Ensembl chr  X:132,421,942...132,422,033
JBrowse link
G Mir93 microRNA 93 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3629917|MGI:3629918|MGI:3718454 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor involved_in ISO (PMID:20959462) RGD PMID:20959462 NCBI chr 5:166,820,075...166,831,951
Ensembl chr 5:166,820,161...166,831,949
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:28747345)
MGI:6369059 (MGI:6099440|PMID:28747345)
Ensembl
RGD
PMID:28747345 GO_REF:0000107 MGI:6099440 NCBI chr10:83,590,052...83,598,620
Ensembl chr10:83,590,071...83,598,620
JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO MGI:5642301 (MGI:5586917|PMID:25074913) RGD PMID:25074913 MGI:5586917 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325
JBrowse link
negative regulation of mature B cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO MGI:1857117|MGI:2683027 (MGI:3619310|PMID:14607964) RGD PMID:14607964 MGI:3619310 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISS
ISO
GO_REF:0000024
(PMID:15878976)
UniProt
RGD
PMID:15878976 GO_REF:0000024 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (MGI:3773489|PMID:18056708) RGD PMID:18056708 MGI:3773489 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd74 CD74 molecule involved_in ISS
ISO
GO_REF:0000024
(MGI:3773489|PMID:18056708)
BHF-UCL
RGD
PMID:18056708 GO_REF:0000024 MGI:3773489 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (MGI:3773489|PMID:18056708) RGD PMID:18056708 MGI:3773489 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
positive regulation of B cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07029605.1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97250 (MGI:2152245|PMID:11604501)
Ensembl
RGD
PMID:11604501 GO_REF:0000107 MGI:2152245 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (MGI:3757615|PMID:8920854) RGD PMID:8920854 MGI:3757615 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Fnip1 folliculin interacting protein 1 acts_upstream_of_or_within
involved_in
ISO
ISS
MGI:5437714|MGI:97250 (MGI:5436190|PMID:22608497)
GO_REF:0000024
RGD
UniProt
PMID:22608497 GO_REF:0000024 MGI:5436190 NCBI chr10:38,567,728...38,650,824
Ensembl chr10:38,567,729...38,650,824
JBrowse link
G Il10 interleukin 10 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:9184696)
UniProt
RGD
PMID:9184696 GO_REF:0000024 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:99702 (MGI:2152245|PMID:11604501) RGD PMID:11604501 MGI:2152245 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
regulation of B cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IBA
ISO
PMID:21873635
(MGI:82730|PMID:9064343)
RGD PMID:9064343 PMID:21873635 MGI:82730, RGD:13792537 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:1857466 (MGI:1331250|PMID:9990064) RGD PMID:9990064 MGI:1331250 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 19834
    cellular process 18637
      cell death 2173
        programmed cell death 1978
          apoptotic process 1923
            leukocyte apoptotic process 142
              lymphocyte apoptotic process 102
                B cell apoptotic process 41
                  B cell deletion + 0
                  B cell receptor apoptotic signaling pathway 1
                  activation-induced B cell apoptotic process 0
                  mature B cell apoptotic process + 5
                  negative regulation of B cell apoptotic process + 23
                  positive regulation of B cell apoptotic process + 6
                  regulation of B cell apoptotic process + 32
paths to the root