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ONTOLOGY REPORT - ANNOTATIONS


Term:establishment of T cell polarity
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Accession:GO:0001768 term browser browse the term
Definition:The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.
Synonyms:exact_synonym: T cell polarization;   T lymphocyte polarization;   establishment of T lymphocyte polarity


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establishment of T cell polarity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL19 C-C motif chemokine ligand 19 involved_in IDA (PMID:12729902) BHF-UCL PMID:12729902 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276
JBrowse link
G CCL21 C-C motif chemokine ligand 21 involved_in IDA (PMID:12729902) BHF-UCL PMID:12729902 NCBI chr 9:34,709,005...34,710,136
Ensembl chr 9:34,709,005...34,710,136
JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IC (PMID:12729902) BHF-UCL PMID:12729902 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,553,769...40,565,472
JBrowse link
G CRTAM cytotoxic and regulatory T cell molecule involved_in ISS UniProt GO_REF:0000024 NCBI chr11:122,838,419...122,872,643
Ensembl chr11:122,838,500...122,872,643
JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5547469|PMID:23991089) Ensembl
MGI
PMID:23991089 GO_REF:0000107 MGI:5547469 NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,147,862
JBrowse link
G DOCK2 dedicator of cytokinesis 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2668308|PMID:12871644) Ensembl
MGI
PMID:12871644 GO_REF:0000107 MGI:2668308 NCBI chr 5:169,637,247...170,083,382
Ensembl chr 5:169,637,268...170,083,382
JBrowse link
G MYH9 myosin heavy chain 9 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3041667|PMID:15064761) Ensembl
MGI
PMID:15064761 GO_REF:0000107 MGI:3041667 NCBI chr22:36,281,280...36,387,967
Ensembl chr22:36,281,280...36,387,967
JBrowse link
G SCRIB scribble planar cell polarity protein involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:143,790,925...143,815,773
Ensembl chr 8:143,790,920...143,815,773
JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:111,555,381...111,605,878
Ensembl chr 6:111,555,381...111,606,906
JBrowse link
negative regulation of establishment of T cell polarity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RIPOR2 RHO family interacting cell polarization regulator 2 involved_in IMP (PMID:23241886) UniProt PMID:23241886 NCBI chr 6:24,804,284...25,042,288
Ensembl chr 6:24,804,282...25,042,170
JBrowse link
positive regulation of establishment of T cell polarity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DOCK8 dedicator of cytokinesis 8 involved_in IMP (PMID:28028151) UniProt PMID:28028151 NCBI chr 9:211,296...465,260
Ensembl chr 9:214,854...465,259
JBrowse link
G FLOT2 flotillin 2 involved_in IMP (PMID:21696602) UniProt PMID:21696602 NCBI chr17:28,879,339...28,897,733
Ensembl chr17:28,879,335...28,897,733
JBrowse link
regulation of establishment of T cell polarity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin involved_in IMP (PMID:23575248) UniProt PMID:23575248 NCBI chr 9:121,201,483...121,332,844
Ensembl chr 9:121,207,794...121,332,843
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18537
    cellular process 17456
      establishment or maintenance of cell polarity 248
        establishment of cell polarity 158
          establishment of lymphocyte polarity 14
            establishment of T cell polarity 13
              negative regulation of establishment of T cell polarity 1
              positive regulation of establishment of T cell polarity 2
              regulation of establishment of T cell polarity + 4
Path 2
Term Annotations click to browse term
  biological_process 18537
    cellular process 17456
      cell activation 1251
        leukocyte activation 1091
          lymphocyte activation 903
            T cell activation 569
              establishment of T cell polarity 13
                negative regulation of establishment of T cell polarity 1
                positive regulation of establishment of T cell polarity 2
                regulation of establishment of T cell polarity + 4
paths to the root