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ONTOLOGY REPORT - ANNOTATIONS


Term:organ induction
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Accession:GO:0001759 term browser browse the term
Definition:The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ.
Synonyms:exact_synonym: induction of an organ


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organ induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO (MGI:1306869|PMID:9806931) MGI PMID:9806931 MGI:1306869 NCBI chrNW_004936697:1,054,237...1,061,468 JBrowse link
G Fgf1 fibroblast growth factor 1 acts_upstream_of_or_within ISO (MGI:3511765|PMID:15576401) MGI PMID:15576401 MGI:3511765 NCBI chrNW_004936504:11,590,687...11,684,410 JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO (MGI:2662946|PMID:12810586)
PMID:10964474
MGI PMID:10964474 PMID:12810586 MGI:2662946 RGD:8554722 NCBI chrNW_004936480:18,114,231...18,195,884 JBrowse link
G Fgf3 fibroblast growth factor 3 acts_upstream_of_or_within ISO (MGI:2662946|PMID:12810586)
(MGI:3530177|PMID:15741321)
MGI PMID:12810586 PMID:15741321 MGI:2662946 MGI:3530177 NCBI chrNW_004936599:868,634...875,464 JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO (MGI:3530177|PMID:15741321) MGI PMID:15741321 MGI:3530177 NCBI chrNW_004936600:4,004,847...4,010,626 JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (MGI:3511765|PMID:15576401) MGI PMID:15576401 MGI:3511765 NCBI chrNW_004936710:1,760,365...1,815,269 JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 acts_upstream_of_or_within ISO (MGI:3511765|PMID:15576401) MGI PMID:15576401 MGI:3511765 NCBI chrNW_004936597:1,388,394...1,397,731 JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 acts_upstream_of_or_within ISO (MGI:3513737|PMID:15569927) MGI PMID:15569927 MGI:3513737 NCBI chrNW_004936545:7,286,018...7,407,623 JBrowse link
G Gdnf glial cell derived neurotrophic factor acts_upstream_of_or_within ISO (MGI:3530708|PMID:15691764) MGI PMID:15691764 MGI:3530708 NCBI chrNW_004936518:4,291,391...4,310,752 JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of_or_within ISO (MGI:3036921|PMID:12050119) MGI PMID:12050119 MGI:3036921 NCBI chrNW_004936478:3,809,288...3,813,014 JBrowse link
G Hoxc11 homeobox C11 acts_upstream_of_or_within ISO (MGI:3036921|PMID:12050119) MGI PMID:12050119 MGI:3036921 NCBI chrNW_004936512:11,194,876...11,197,316 JBrowse link
G Six1 SIX homeobox 1 acts_upstream_of_or_within ISO (MGI:2662002|PMID:12783782) MGI PMID:12783782 MGI:2662002 NCBI chrNW_004936495:4,839,496...4,842,906 JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 acts_upstream_of_or_within ISO (MGI:3530708|PMID:15691764) MGI PMID:15691764 MGI:3530708 NCBI chrNW_004936662:2,241,928...2,245,616 JBrowse link
activation of prostate induction by androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor acts_upstream_of_or_within ISO (MGI:3714080|PMID:17317769) MGI PMID:17317769 MGI:3714080 NCBI chrNW_004936635:485,903...647,820 JBrowse link
BMP signaling pathway involved in heart induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317 NCBI chrNW_004936485:12,428,765...12,439,570 JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISO (PMID:20702560) BHF-UCL PMID:20702560 NCBI chrNW_004936697:1,054,237...1,061,468 JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317 NCBI chrNW_004936837:827,568...838,933 JBrowse link
lung induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO (MGI:4361775|PMID:19805295)
(MGI:4360856|PMID:19686689)
MGI PMID:19686689 PMID:19805295 MGI:4360856 MGI:4361775 NCBI chrNW_004936473:29,999,542...30,034,610 JBrowse link
G Wnt2 Wnt family member 2 acts_upstream_of_or_within ISO (MGI:4360856|PMID:19686689) MGI PMID:19686689 MGI:4360856 NCBI chrNW_004936589:1,825,209...1,866,898 JBrowse link
G Wnt2b Wnt family member 2B acts_upstream_of_or_within ISO (MGI:4360856|PMID:19686689) MGI PMID:19686689 MGI:4360856 NCBI chrNW_004936690:1,077,538...1,094,005 JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317 NCBI chrNW_004936864:150,742...179,205 JBrowse link
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (MGI:3835736|PMID:18297060) BHF-UCL PMID:18297060 MGI:3835736 NCBI chrNW_004936787:307,290...309,963 JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:3835736|PMID:18297060) BHF-UCL PMID:18297060 MGI:3835736 NCBI chrNW_004936483:15,533,264...15,534,576 JBrowse link
G Wnt11 Wnt family member 11 involved_in ISO (MGI:5424267|PMID:22569553) CACAO PMID:22569553 MGI:5424267 NCBI chrNW_004936498:4,909,041...4,927,482 JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (MGI:5424267|PMID:22569553) CACAO PMID:22569553 MGI:5424267 NCBI chrNW_004936473:6,031,627...6,052,211 JBrowse link
positive regulation of Notch signaling pathway involved in heart induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata5 GATA binding protein 5 involved_in ISO (MGI:5286818|PMID:21633169) BHF-UCL PMID:21633169 MGI:5286818 NCBI chrNW_004936514:10,061,675...10,070,541 JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) BHF-UCL PMID:18593560 MGI:4441249 NCBI chrNW_004936483:15,533,264...15,534,576 JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004936505:4,329,428...4,711,310 JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004936505:5,544,011...6,747,417 JBrowse link
regulation of heart induction by regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317 NCBI chrNW_004936837:827,568...838,933 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12295
    developmental process 5793
      developmental induction 40
        organ induction 27
          heart induction + 11
          lung induction + 3
          pancreas induction 0
          prostate induction + 1
Path 2
Term Annotations click to browse term
  biological_process 12295
    developmental process 5793
      anatomical structure development 5417
        multicellular organism development 4956
          system development 4647
            animal organ development 3583
              animal organ morphogenesis 1039
                animal organ formation 74
                  regulation of animal organ formation 32
                    organ induction 27
                      heart induction + 11
                      lung induction + 3
                      pancreas induction 0
                      prostate induction + 1
paths to the root