Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:ruffle
go back to main search page
Accession:GO:0001726 term browser browse the term
Definition:Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
Synonyms:related_synonym: membrane ruffle
 never_in_taxon: NCBITaxon:2 ! Bacteria;   NCBITaxon:33090 ! Viridiplantae;   NCBITaxon:4751 ! Fungi;   NCBITaxon:4890 ! Ascomycota


show annotations for term's descendants           Sort by:
ruffle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase located_in ISO
IEA		 RGD
Ensembl		 PMID:16831423 GO_REF:0000107 RGD:1598670 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 located_in IDA (PMID:11062263) MGI PMID:11062263 NCBI chr 3:195,274,745...195,443,020
Ensembl chr 3:195,274,745...195,443,044 		JBrowse link
G ACTN1 actinin alpha 1 located_in IEA
IDA		 (PMID:11223950) UniProt
Ensembl		 PMID:11223950 GO_REF:0000044 GO_REF:0000107 NCBI chr14:68,874,128...68,979,302
Ensembl chr14:68,874,128...68,979,440 		JBrowse link
G ACTR3 actin related protein 3 ISO RGD PMID:10209028 RGD:2306208 NCBI chr 2:113,889,934...113,962,596
Ensembl chr 2:113,890,063...113,962,596 		JBrowse link
G AIF1 allograft inflammatory factor 1 located_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 located_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:201,700,267...201,780,933
Ensembl chr 2:201,700,267...201,782,112 		JBrowse link
G AMOT angiomotin located_in IDA (PMID:11257124) MGI PMID:11257124 NCBI chr  X:112,774,877...112,840,831
Ensembl chr  X:112,774,503...112,840,831 		JBrowse link
G ANXA2 annexin A2 ISO RGD PMID:19193640 RGD:7242275 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883 		JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 located_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 located_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr12:105,173,300...105,236,174
Ensembl chr12:105,173,297...105,236,203 		JBrowse link
G ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 located_in IEA UniProt GO_REF:0000044 NCBI chr 5:141,653,402...141,682,230
Ensembl chr 5:141,653,401...141,682,230 		JBrowse link
G ARF6 ADP ribosylation factor 6 located_in
is_active_in		 ISO
IEA
IBA
IDA		 (PMID:9312003) RGD
TreeGrafter
GO_Central
UniProt
Ensembl		 PMID:9312003 PMID:11950936 GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 GO_REF:0000118 RGD:727254 NCBI chr14:49,893,082...49,897,054
Ensembl chr14:49,893,079...49,897,054 		JBrowse link
G ARFIP2 ADP ribosylation factor interacting protein 2 located_in IMP (PMID:8670882) UniProt PMID:8670882 NCBI chr11:6,476,519...6,481,331
Ensembl chr11:6,474,683...6,481,479 		JBrowse link
G ARHGAP1 Rho GTPase activating protein 1 located_in ISO (PMID:15860730) MGI PMID:15860730 NCBI chr11:46,677,080...46,700,619
Ensembl chr11:46,677,080...46,700,619 		JBrowse link
G ARHGAP18 Rho GTPase activating protein 18 part_of IDA (PMID:28251925) CACAO PMID:28251925 NCBI chr 6:129,576,132...129,710,177
Ensembl chr 6:129,576,132...129,710,177 		JBrowse link
G ARHGEF26 Rho guanine nucleotide exchange factor 26 located_in IEA UniProt GO_REF:0000044 NCBI chr 3:154,121,003...154,257,825
Ensembl chr 3:154,121,003...154,257,827 		JBrowse link
G ARHGEF7 Rho guanine nucleotide exchange factor 7 located_in IEA UniProt GO_REF:0000044 NCBI chr13:111,114,619...111,305,734
Ensembl chr13:111,114,559...111,305,737 		JBrowse link
G ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 located_in
is_active_in		 IDA
IEA
IBA		 (PMID:18400762) UniProt
TreeGrafter
GO_Central		 PMID:18400762 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:23,428,563...23,484,631
Ensembl chr 1:23,428,563...23,484,637 		JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:20,197,381...20,221,696
Ensembl chr 8:20,197,381...20,226,819 		JBrowse link
G BAIAP2 BAR/IMD domain containing adaptor protein 2 located_in IEA UniProt GO_REF:0000044 NCBI chr17:81,035,151...81,117,434
Ensembl chr17:81,035,122...81,117,434 		JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member located_in IDA
ISS		 (PMID:9472046) UniProt PMID:9472046 GO_REF:0000024 NCBI chr16:75,228,181...75,268,007
Ensembl chr16:75,228,181...75,268,053 		JBrowse link
G BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 located_in
is_active_in		 IEA
ISO		 (PMID:19116644) Ensembl
MGI		 PMID:19116644 GO_REF:0000107 NCBI chr15:45,587,123...45,609,716
Ensembl chr15:45,587,214...45,615,945 		JBrowse link
G C2CD5 C2 calcium dependent domain containing 5 located_in IEA UniProt GO_REF:0000044 NCBI chr12:22,448,583...22,544,542
Ensembl chr12:22,448,583...22,544,546 		JBrowse link
G CAPG capping actin protein, gelsolin like located_in IEA UniProt GO_REF:0000044 NCBI chr 2:85,391,602...85,419,540
Ensembl chr 2:85,394,753...85,418,432 		JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 located_in IDA
IEA		 (PMID:26466680), (PMID:26578515) UniProt PMID:26466680 PMID:26578515 GO_REF:0000044 NCBI chr16:67,645,144...67,657,569
Ensembl chr16:67,644,988...67,657,569 		JBrowse link
G CD2AP CD2 associated protein located_in IEA
IDA		 (PMID:10339567) UniProt PMID:10339567 GO_REF:0000044 NCBI chr 6:47,477,789...47,627,263
Ensembl chr 6:47,477,789...47,627,263 		JBrowse link
G CDK6 cyclin dependent kinase 6 located_in IEA
IDA		 (PMID:10205165) UniProt
BHF-UCL		 PMID:10205165 GO_REF:0000044 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
G CIT citron rho-interacting serine/threonine kinase located_in ISO (PMID:12781320) MGI PMID:12781320 NCBI chr12:119,685,791...119,877,320
Ensembl chr12:119,685,791...119,877,320 		JBrowse link
G CLIP1 CAP-Gly domain containing linker protein 1 located_in IEA UniProt GO_REF:0000044 NCBI chr12:122,271,469...122,422,956
Ensembl chr12:122,271,432...122,422,669 		JBrowse link
G COBL cordon-bleu WH2 repeat protein located_in
is_active_in		 IEA
IBA
ISS		 UniProt
TreeGrafter
GO_Central
BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:51,016,212...51,316,809
Ensembl chr 7:51,016,212...51,316,818 		JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:75,674,322...75,713,466
Ensembl chr15:75,674,322...75,712,848 		JBrowse link
G CTTN cortactin located_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr11:70,398,529...70,436,575
Ensembl chr11:70,398,404...70,436,584 		JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 located_in ISS
IEA		 UniProt GO_REF:0000024 GO_REF:0000044 NCBI chr15:22,867,052...22,980,898
Ensembl chr15:22,867,052...22,981,063 		JBrowse link
G CYTH2 cytohesin 2 ISO RGD PMID:12032543 RGD:625544 NCBI chr19:48,469,369...48,482,314
Ensembl chr19:48,469,208...48,482,314 		JBrowse link
G CYTH3 cytohesin 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:6,161,779...6,272,624
Ensembl chr 7:6,161,779...6,272,644 		JBrowse link
G DBNL drebrin like located_in IEA
ISS		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr 7:44,044,702...44,069,456
Ensembl chr 7:44,044,640...44,069,456 		JBrowse link
G EZR ezrin located_in IDA (PMID:25554515), (PMID:9852149) UniProt PMID:9852149 PMID:25554515 NCBI chr 6:158,765,748...158,819,368
Ensembl chr 6:158,765,741...158,819,368 		JBrowse link
G FGD1 FYVE, RhoGEF and PH domain containing 1 located_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr  X:54,445,454...54,496,234
Ensembl chr  X:54,445,454...54,496,234 		JBrowse link
G FGD2 FYVE, RhoGEF and PH domain containing 2 located_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:37,005,655...37,029,069
Ensembl chr 6:37,005,646...37,029,069 		JBrowse link
G FGD3 FYVE, RhoGEF and PH domain containing 3 located_in ISS UniProt GO_REF:0000024 NCBI chr 9:92,947,523...93,036,233
Ensembl chr 9:92,947,523...93,036,236 		JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 located_in ISS UniProt GO_REF:0000024 NCBI chr12:32,399,558...32,646,050
Ensembl chr12:32,399,558...32,646,050 		JBrowse link
G FGD5 FYVE, RhoGEF and PH domain containing 5 located_in ISS UniProt GO_REF:0000024 NCBI chr 3:14,810,688...14,934,571
Ensembl chr 3:14,810,853...14,934,571 		JBrowse link
G FGD6 FYVE, RhoGEF and PH domain containing 6 located_in ISS UniProt GO_REF:0000024 NCBI chr12:95,076,749...95,217,467
Ensembl chr12:95,076,749...95,217,482 		JBrowse link
G FRMD4B FERM domain containing 4B located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:69,168,782...69,542,586
Ensembl chr 3:69,168,782...69,542,583 		JBrowse link
G FSCN1 fascin actin-bundling protein 1 located_in
is_active_in		 ISO
IEA
IBA
IDA		 (PMID:3525578) RGD
TreeGrafter
GO_Central
UniProt		 PMID:3525578 PMID:7657718 GO_REF:0000033 GO_REF:0000118 RGD:2317778 NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655 		JBrowse link
G FSCN3 fascin actin-bundling protein 3 is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:127,593,736...127,602,144
Ensembl chr 7:127,591,409...127,602,144 		JBrowse link
G GAS7 growth arrest specific 7 located_in ISO (PMID:11795944) MGI PMID:11795944 NCBI chr17:9,910,606...10,198,606
Ensembl chr17:9,910,606...10,198,606 		JBrowse link
G GNAS GNAS complex locus located_in ISO
IEA		 Gnas, Alex RGD
UniProt		 PMID:11447126 GO_REF:0000044 RGD:5509808 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192 		JBrowse link
G GSN gelsolin ISO RGD PMID:16280379 RGD:1599859 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843 		JBrowse link
G INPP5E inositol polyphosphate-5-phosphatase E located_in ISO
IEA		 RGD
Ensembl
UniProt		 PMID:10405344 GO_REF:0000044 GO_REF:0000107 RGD:1299274 NCBI chr 9:136,428,619...136,439,845
Ensembl chr 9:136,428,619...136,439,845 		JBrowse link
G INPP5J inositol polyphosphate-5-phosphatase J located_in
is_active_in		 ISO
IEA
IBA
IDA		 (PMID:12536145) RGD
TreeGrafter
GO_Central
MGI		 PMID:10593988 PMID:12536145 GO_REF:0000033 GO_REF:0000118 RGD:633686 NCBI chr22:31,122,614...31,134,697
Ensembl chr22:31,122,731...31,134,697 		JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K located_in
is_active_in		 IDA
IEA
IBA		 (PMID:12536145) MGI
TreeGrafter
GO_Central		 PMID:12536145 GO_REF:0000033 GO_REF:0000118 NCBI chr17:1,494,577...1,516,612
Ensembl chr17:1,494,577...1,516,742 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 located_in IDA (PMID:25554515), (PMID:26242911) UniProt PMID:25554515 PMID:26242911 NCBI chr15:90,388,242...90,502,239
Ensembl chr15:90,388,242...90,502,239 		JBrowse link
G ITGA5 integrin subunit alpha 5 located_in TAS (PMID:11919189) HGNC-UCL PMID:11919189 NCBI chr12:54,395,261...54,419,266
Ensembl chr12:54,395,261...54,419,266 		JBrowse link
G ITGB1 integrin subunit beta 1 located_in TAS (PMID:11919189) HGNC-UCL PMID:11919189 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G ITGB1BP1 integrin subunit beta 1 binding protein 1 located_in
is_active_in		 IDA
IEA
IBA		 (PMID:11919189) HGNC-UCL
TreeGrafter
GO_Central
UniProt
Ensembl		 PMID:11919189 GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:9,403,475...9,423,569
Ensembl chr 2:9,403,475...9,423,528 		JBrowse link
G KIF18A kinesin family member 18A located_in IDA
IEA		 (PMID:17006958) UniProt PMID:17006958 GO_REF:0000044 NCBI chr11:28,020,619...28,108,156
Ensembl chr11:28,020,619...28,108,156 		JBrowse link
G KLHL2 kelch like family member 2 located_in IEA UniProt GO_REF:0000044 NCBI chr 4:165,207,561...165,323,156
Ensembl chr 4:165,207,561...165,323,156 		JBrowse link
G KLHL41 kelch like family member 41 located_in IEA UniProt GO_REF:0000044 NCBI chr 2:169,509,702...169,526,258
Ensembl chr 2:169,509,702...169,526,258 		JBrowse link
G KNSTRN kinetochore localized astrin (SPAG5) binding protein located_in IDA (PMID:26242911) ARUK-UCL PMID:26242911 NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288 		JBrowse link
G LAYN layilin located_in ISS HGNC-UCL GO_REF:0000024 NCBI chr11:111,540,280...111,561,745
Ensembl chr11:111,540,280...111,561,745 		JBrowse link
G LCP1 lymphocyte cytosolic protein 1 located_in IEA
ISS
IMP		 (PMID:16636079) Ensembl
ARUK-UCL
UniProt		 PMID:16636079 GO_REF:0000024 GO_REF:0000107 NCBI chr13:46,125,923...46,182,177
Ensembl chr13:46,125,920...46,211,871 		JBrowse link
G LIMA1 LIM domain and actin binding 1 located_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:50,175,788...50,283,520
Ensembl chr12:50,175,788...50,283,520 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin located_in IEA UniProt GO_REF:0000044 NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633 		JBrowse link
G MKLN1 muskelin 1 located_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr 7:131,110,094...131,496,632
Ensembl chr 7:131,110,096...131,496,632 		JBrowse link
G MTM1 myotubularin 1 located_in IEA
IDA		 (PMID:12118066) UniProt PMID:12118066 GO_REF:0000044 NCBI chr  X:150,562,653...150,673,143
Ensembl chr  X:150,568,417...150,673,143 		JBrowse link
G MTMR14 myotubularin related protein 14 located_in IDA (PMID:17008356) UniProt PMID:17008356 NCBI chr 3:9,649,505...9,702,393
Ensembl chr 3:9,649,433...9,702,393 		JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 located_in NAS (PMID:12570871) UniProt PMID:12570871 NCBI chr 8:124,550,784...124,728,473
Ensembl chr 8:124,550,784...124,728,473 		JBrowse link
G MTSS2 MTSS I-BAR domain containing 2 located_in IEA UniProt
Ensembl		 GO_REF:0000044 GO_REF:0000107 NCBI chr16:70,661,204...70,686,053
Ensembl chr16:70,661,204...70,686,053 		JBrowse link
G MYADM myeloid associated differentiation marker located_in IDA (PMID:21325632) UniProt PMID:21325632 NCBI chr19:53,865,628...53,876,435
Ensembl chr19:53,864,763...53,876,435 		JBrowse link
G MYH9 myosin heavy chain 9 located_in IDA (PMID:16403913) UniProt PMID:16403913 NCBI chr22:36,281,280...36,387,967
Ensembl chr22:36,281,280...36,388,010 		JBrowse link
G MYO10 myosin X located_in IEA UniProt GO_REF:0000044 NCBI chr 5:16,661,907...16,936,288
Ensembl chr 5:16,661,907...16,936,288 		JBrowse link
G MYO5A myosin VA located_in IDA (PMID:9852149) UniProt PMID:9852149 NCBI chr15:52,307,283...52,529,050
Ensembl chr15:52,307,281...52,529,132 		JBrowse link
G MYO6 myosin VI located_in
is_active_in		 IDA
IEA
IBA		 (PMID:16507995), (PMID:9852149) UniProt
TreeGrafter
GO_Central		 PMID:9852149 PMID:16507995 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:75,749,239...75,919,537
Ensembl chr 6:75,749,201...75,919,537 		JBrowse link
G MYO9B myosin IXB is_active_in
located_in		 ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter		 PMID:9348541 GO_REF:0000033 GO_REF:0000118 RGD:1581711 NCBI chr19:17,075,777...17,213,286
Ensembl chr19:17,075,777...17,214,537 		JBrowse link
G NCKAP1 NCK associated protein 1 located_in ISS BHF-UCL GO_REF:0000024 NCBI chr 2:182,909,115...183,038,457
Ensembl chr 2:182,909,115...183,038,858 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor located_in IEA Ensembl GO_REF:0000107 NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,556...29,698,598 		JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 located_in IEA UniProt GO_REF:0000044 NCBI chr17:74,748,628...74,769,353
Ensembl chr17:74,748,628...74,769,353 		JBrowse link
G NME1-NME2 NME1-NME2 readthrough located_in IEA
IDA		 (PMID:11919189) UniProt
HGNC-UCL		 PMID:11919189 GO_REF:0000044 NCBI chr17:51,153,559...51,171,744
Ensembl chr17:51,153,590...51,171,744 		JBrowse link
G NME2 NME/NM23 nucleoside diphosphate kinase 2 located_in IDA
IEA		 (PMID:11919189) HGNC-UCL
UniProt		 PMID:11919189 GO_REF:0000044 NCBI chr17:51,165,536...51,171,744
Ensembl chr17:51,165,435...51,171,744 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 located_in ISO
IDA		 (PMID:12912914) RGD
UniProt		 PMID:12912914 PMID:19574218 RGD:11533928 NCBI chr11:77,322,017...77,530,009
Ensembl chr11:77,322,017...77,474,635 		JBrowse link
G PALLD palladin, cytoskeletal associated protein located_in ISO
IEA		 RGD
UniProt		 PMID:16868024 GO_REF:0000044 RGD:2325783 NCBI chr 4:168,497,052...168,928,441
Ensembl chr 4:168,497,052...168,928,457 		JBrowse link
G PARD6A par-6 family cell polarity regulator alpha located_in IEA UniProt GO_REF:0000044 NCBI chr16:67,660,960...67,662,774
Ensembl chr16:67,660,946...67,662,774 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta located_in ISO (PMID:26437238) MGI PMID:26437238 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872 		JBrowse link
G PDLIM7 PDZ and LIM domain 7 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:177,483,394...177,497,604
Ensembl chr 5:177,483,394...177,497,606 		JBrowse link
G PDPN podoplanin located_in ISS UniProt GO_REF:0000024 NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:9148965 RGD:11541088 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha located_in IEA UniProt GO_REF:0000044 NCBI chr 1:151,195,419...151,249,531
Ensembl chr 1:151,197,949...151,249,536 		JBrowse link
G PLCG1 phospholipase C gamma 1 located_in IDA
IEA		 (PMID:17229814) UniProt PMID:17229814 GO_REF:0000044 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801 		JBrowse link
G PODXL podocalyxin like located_in IDA
IEA		 (PMID:18456258) UniProt PMID:18456258 GO_REF:0000044 NCBI chr 7:131,500,271...131,556,628
Ensembl chr 7:131,500,262...131,558,217 		JBrowse link
G PTK6 protein tyrosine kinase 6 located_in IEA
IDA		 (PMID:15572663) UniProt PMID:15572663 GO_REF:0000044 NCBI chr20:63,528,001...63,537,376
Ensembl chr20:63,528,001...63,537,376 		JBrowse link
G RAB22A RAB22A, member RAS oncogene family located_in IEA UniProt GO_REF:0000044 NCBI chr20:58,309,715...58,367,507
Ensembl chr20:58,309,715...58,367,507 		JBrowse link
G RAB34 RAB34, member RAS oncogene family located_in ISO (PMID:12446704) MGI PMID:12446704 NCBI chr17:28,714,281...28,718,428
Ensembl chr17:28,714,281...28,718,429 		JBrowse link
G RAB5A RAB5A, member RAS oncogene family located_in IEA Ensembl
UniProt		 GO_REF:0000044 GO_REF:0000107 NCBI chr 3:19,947,097...19,985,175
Ensembl chr 3:19,947,097...19,985,175 		JBrowse link
G RASA1 RAS p21 protein activator 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:87,267,883...87,391,916
Ensembl chr 5:87,267,883...87,391,931 		JBrowse link
G RDX radixin located_in ISO (PMID:9563848) MGI PMID:9563848 NCBI chr11:110,174,922...110,296,614
Ensembl chr11:109,864,295...110,296,712 		JBrowse link
G RINL Ras and Rab interactor like located_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr19:38,867,830...38,878,275
Ensembl chr19:38,867,830...38,878,275 		JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 located_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr18:20,946,906...21,111,813
Ensembl chr18:20,944,612...21,111,813 		JBrowse link
G S100A11 S100 calcium binding protein A11 located_in IDA (PMID:10913138) UniProt PMID:10913138 NCBI chr 1:152,032,506...152,037,004
Ensembl chr 1:152,032,506...152,047,907 		JBrowse link
G S100A6 S100 calcium binding protein A6 located_in IDA (PMID:10913138) UniProt PMID:10913138 NCBI chr 1:153,534,599...153,535,991
Ensembl chr 1:153,534,599...153,536,244 		JBrowse link
G S100B S100 calcium binding protein B located_in IDA (PMID:10913138) UniProt PMID:10913138 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 located_in IEA UniProt GO_REF:0000044 NCBI chr21:14,485,228...14,659,417
Ensembl chr21:14,485,228...14,658,821 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein located_in IEA
ISS		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
G SH2B2 SH2B adaptor protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:102,285,141...102,321,711
Ensembl chr 7:102,285,091...102,321,711 		JBrowse link
G SNX5 sorting nexin 5 located_in IEA UniProt GO_REF:0000044 NCBI chr20:17,941,600...17,968,794
Ensembl chr20:17,941,597...17,968,980 		JBrowse link
G SNX9 sorting nexin 9 located_in IEA UniProt GO_REF:0000044 NCBI chr 6:157,823,246...157,945,077
Ensembl chr 6:157,700,387...157,945,077 		JBrowse link
G TESC tescalcin located_in ISS UniProt GO_REF:0000024 NCBI chr12:117,038,923...117,099,416
Ensembl chr12:117,038,923...117,099,479 		JBrowse link
G TLN1 talin 1 located_in IEA
ISS		 InterPro
HGNC-UCL		 GO_REF:0000002 GO_REF:0000024 NCBI chr 9:35,696,948...35,732,195
Ensembl chr 9:35,696,948...35,732,195 		JBrowse link
G TLN2 talin 2 located_in IEA InterPro GO_REF:0000002 NCBI chr15:62,390,550...62,844,631
Ensembl chr15:62,390,526...62,844,631 		JBrowse link
G TLR4 toll like receptor 4 located_in IEA UniProt GO_REF:0000044 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TMEM87A transmembrane protein 87A located_in IDA
IEA		 (PMID:32228863) UniProt PMID:32228863 GO_REF:0000044 NCBI chr15:42,210,447...42,273,584
Ensembl chr15:42,210,447...42,273,534 		JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A located_in ISO (PMID:14573547) MGI PMID:14573547 NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,383 		JBrowse link
G TRPM7 transient receptor potential cation channel subfamily M member 7 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:50,557,158...50,686,797
Ensembl chr15:50,552,473...50,686,797 		JBrowse link
G VIL1 villin 1 located_in IEA
IDA		 (PMID:15342783), (PMID:17229814), (PMID:17606613) UniProt PMID:15342783 PMID:17229814 PMID:17606613 GO_REF:0000044 NCBI chr 2:218,419,123...218,453,295
Ensembl chr 2:218,419,121...218,453,295 		JBrowse link
G WASF2 WASP family member 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:27,404,230...27,490,167
Ensembl chr 1:27,404,230...27,490,167 		JBrowse link
G WIPF1 WAS/WASL interacting protein family member 1 located_in IEA UniProt GO_REF:0000044 NCBI chr 2:174,559,574...174,682,913
Ensembl chr 2:174,559,572...174,682,916 		JBrowse link
ruffle membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA7 ATP binding cassette subfamily A member 7 located_in IEA
ISS		 UniProt
Alzheimers_University_of_Toronto		 GO_REF:0000024 GO_REF:0000044 NCBI chr19:1,040,107...1,065,572
Ensembl chr19:1,039,997...1,065,572 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 located_in IDA (PMID:14970227) BHF-UCL PMID:14970227 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G ADGRE2 adhesion G protein-coupled receptor E2 located_in IEA UniProt GO_REF:0000044 NCBI chr19:14,724,171...14,778,560
Ensembl chr19:14,732,392...14,778,560 		JBrowse link
G AIF1 allograft inflammatory factor 1 located_in IEA
IBA
IDA		 (PMID:18699778) Ensembl
TreeGrafter
GO_Central
UniProt		 PMID:18699778 GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G AIF1L allograft inflammatory factor 1 like located_in IEA
IBA		 UniProt
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000044 GO_REF:0000118 NCBI chr 9:131,096,531...131,123,144
Ensembl chr 9:131,096,476...131,123,152 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 located_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536 		JBrowse link
G APC APC regulator of WNT signaling pathway located_in IEA
IDA		 (PMID:19151759) UniProt PMID:19151759 GO_REF:0000044 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 located_in IEA
ISS		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr12:105,173,300...105,236,174
Ensembl chr12:105,173,297...105,236,203 		JBrowse link
G ARF4 ADP ribosylation factor 4 located_in IDA (PMID:12446727) UniProt PMID:12446727 NCBI chr 3:57,571,363...57,597,344
Ensembl chr 3:57,571,363...57,598,220 		JBrowse link
G ARHGAP45 Rho GTPase activating protein 45 located_in IEA UniProt GO_REF:0000044 NCBI chr19:1,065,959...1,086,628
Ensembl chr19:1,065,923...1,086,628 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 located_in
is_active_in		 IEA
IBA
IDA		 (PMID:19043560) UniProt
GO_Central
TreeGrafter		 PMID:19043560 GO_REF:0000033 GO_REF:0000044 GO_REF:0000118 NCBI chr 1:155,946,854...155,979,617
Ensembl chr 1:155,946,851...156,007,070 		JBrowse link
G ARHGEF4 Rho guanine nucleotide exchange factor 4 located_in IEA UniProt GO_REF:0000044 NCBI chr 2:130,836,914...131,047,253
Ensembl chr 2:130,836,914...131,047,263 		JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:17224451 RGD:2306207 NCBI chr 2:218,217,189...218,254,348
Ensembl chr 2:218,217,141...218,254,356 		JBrowse link
G BMX BMX non-receptor tyrosine kinase located_in IDA (PMID:11331870) UniProt PMID:11331870 NCBI chr  X:15,500,807...15,556,519
Ensembl chr  X:15,464,246...15,556,529 		JBrowse link
G C2CD5 C2 calcium dependent domain containing 5 located_in IDA (PMID:21907143) UniProt PMID:21907143 NCBI chr12:22,448,583...22,544,542
Ensembl chr12:22,448,583...22,544,546 		JBrowse link
G CDC37 cell division cycle 37, HSP90 cochaperone ISO RGD PMID:16335536 RGD:5131523 NCBI chr19:10,391,133...10,403,542
Ensembl chr19:10,391,133...10,420,121 		JBrowse link
G CDKL5 cyclin dependent kinase like 5 located_in ISS BHF-UCL GO_REF:0000024 NCBI chr  X:18,425,608...18,653,629
Ensembl chr  X:18,425,583...18,653,629 		JBrowse link
G CFL1 cofilin 1 located_in IEA UniProt GO_REF:0000044 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026 		JBrowse link
G CIB1 calcium and integrin binding 1 located_in IEA UniProt GO_REF:0000044 NCBI chr15:90,229,975...90,265,759
Ensembl chr15:90,229,975...90,234,047 		JBrowse link
G CLASP2 cytoplasmic linker associated protein 2 located_in ISO
IEA
IDA		 MMO:0000686
(PMID:20937854)		 RGD
UniProt		 PMID:20937854 PMID:22992739 GO_REF:0000044 RGD:28912745 NCBI chr 3:33,496,245...33,718,254
Ensembl chr 3:33,496,245...33,718,356 		JBrowse link
G CLCN3 chloride voltage-gated channel 3 located_in IEA UniProt GO_REF:0000044 NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673 		JBrowse link
G CORO1C coronin 1C located_in IEA UniProt GO_REF:0000044 NCBI chr12:108,645,109...108,731,518
Ensembl chr12:108,645,109...108,731,526 		JBrowse link
G DIAPH1 diaphanous related formin 1 located_in IEA UniProt GO_REF:0000044 NCBI chr 5:141,515,021...141,619,000
Ensembl chr 5:141,515,016...141,619,055 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein located_in IDA (PMID:19158340) UniProt PMID:19158340 NCBI chr 8:13,083,361...13,604,620
Ensembl chr 8:13,083,361...13,604,610 		JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:9725914 RGD:9685132 NCBI chr19:10,718,079...10,831,903
Ensembl chr19:10,718,055...10,833,488 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 located_in IDA (PMID:19158340) UniProt PMID:19158340 NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,489,308...73,525,587 		JBrowse link
G EGFR epidermal growth factor receptor is_active_in IDA (PMID:11331309) ARUK-UCL PMID:11331309 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EPB41L5 erythrocyte membrane protein band 4.1 like 5 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:120,013,077...120,179,119
Ensembl chr 2:120,013,077...120,179,119 		JBrowse link
G EPHA2 EPH receptor A2 located_in IEA UniProt GO_REF:0000044 NCBI chr 1:16,124,337...16,156,069
Ensembl chr 1:16,124,337...16,156,069 		JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor located_in
is_active_in		 IEA
IBA
ISS		 Ensembl
GO_Central
TreeGrafter
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 GO_REF:0000118 NCBI chr12:15,620,134...15,789,388
Ensembl chr12:15,620,134...15,882,329 		JBrowse link
G EPS8L1 EPS8 signaling adaptor L1 located_in
is_active_in		 IDA
IEA
IBA		 (PMID:14565974) UniProt
TreeGrafter
GO_Central		 PMID:14565974 GO_REF:0000033 GO_REF:0000118 NCBI chr19:55,075,869...55,087,923
Ensembl chr19:55,072,020...55,087,923 		JBrowse link
G EPS8L2 EPS8 signaling adaptor L2 located_in
is_active_in		 IDA
IEA
IBA		 (PMID:14565974) UniProt
TreeGrafter
GO_Central		 PMID:14565974 GO_REF:0000033 GO_REF:0000118 NCBI chr11:706,231...727,727
Ensembl chr11:694,438...727,727 		JBrowse link
G EPS8L3 EPS8 signaling adaptor L3 is_active_in
located_in		 IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:109,750,080...109,763,923
Ensembl chr 1:109,750,080...109,764,027 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 located_in IEA UniProt GO_REF:0000044 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G EZR ezrin located_in IEA UniProt GO_REF:0000044 NCBI chr 6:158,765,748...158,819,368
Ensembl chr 6:158,765,741...158,819,368 		JBrowse link
G FAM107A family with sequence similarity 107 member A located_in IEA
IDA		 (PMID:20543869) UniProt PMID:20543869 GO_REF:0000044 NCBI chr 3:58,564,117...58,627,610
Ensembl chr 3:58,564,117...58,627,610 		JBrowse link
G FAP fibroblast activation protein alpha located_in IEA
NAS		 (PMID:10455171) UniProt PMID:10455171 GO_REF:0000044 NCBI chr 2:162,170,684...162,243,445
Ensembl chr 2:162,170,684...162,245,151 		JBrowse link
G FERMT1 FERM domain containing kindlin 1 located_in IEA UniProt GO_REF:0000044 NCBI chr20:6,074,845...6,123,030
Ensembl chr20:6,074,845...6,123,214 		JBrowse link
G FGD2 FYVE, RhoGEF and PH domain containing 2 located_in IEA UniProt GO_REF:0000044 NCBI chr 6:37,005,655...37,029,069
Ensembl chr 6:37,005,646...37,029,069 		JBrowse link
G FGD5 FYVE, RhoGEF and PH domain containing 5 located_in IEA UniProt GO_REF:0000044 NCBI chr 3:14,810,688...14,934,571
Ensembl chr 3:14,810,853...14,934,571 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase located_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185 		JBrowse link
G HIP1R huntingtin interacting protein 1 related located_in IDA (PMID:14732715) ParkinsonsUK-UCL PMID:14732715 NCBI chr12:122,834,748...122,862,961
Ensembl chr12:122,834,453...122,862,961 		JBrowse link
G IFIT5 interferon induced protein with tetratricopeptide repeats 5 located_in IDA
IEA		 (PMID:23317505) UniProt PMID:23317505 GO_REF:0000044 NCBI chr10:89,414,568...89,420,997
Ensembl chr10:89,414,568...89,421,605 		JBrowse link
G INPP5J inositol polyphosphate-5-phosphatase J located_in ISO PMID:10593988 MGI PMID:10593988 RGD:633686 NCBI chr22:31,122,614...31,134,697
Ensembl chr22:31,122,731...31,134,697 		JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K located_in IDA (PMID:12556481) UniProt PMID:12556481 NCBI chr17:1,494,577...1,516,612
Ensembl chr17:1,494,577...1,516,742 		JBrowse link
G ITGA5 integrin subunit alpha 5 located_in IDA (PMID:14970227) BHF-UCL PMID:14970227 NCBI chr12:54,395,261...54,419,266
Ensembl chr12:54,395,261...54,419,266 		JBrowse link
G ITGAV integrin subunit alpha V located_in IDA (PMID:25063885) UniProt PMID:25063885 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,010...186,680,901 		JBrowse link
G ITGB1 integrin subunit beta 1 located_in IEA
IDA
NAS		 (PMID:14970227)
(PMID:10455171)		 UniProt
BHF-UCL		 PMID:10455171 PMID:14970227 GO_REF:0000044 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G ITGB3 integrin subunit beta 3 located_in IDA (PMID:25063885) UniProt PMID:25063885 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743 		JBrowse link
G JCAD junctional cadherin 5 associated located_in
is_active_in		 IDA
IBA
IEA		 (PMID:28705794) BHF-UCL
GO_Central
TreeGrafter		 PMID:28705794 GO_REF:0000033 GO_REF:0000118 NCBI chr10:30,012,803...30,115,494
Ensembl chr10:30,012,803...30,115,494 		JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 located_in IEA
IDA		 (PMID:19559006) UniProt PMID:19559006 GO_REF:0000044 NCBI chr 9:470,295...746,103
Ensembl chr 9:470,291...746,105 		JBrowse link
G KSR1 kinase suppressor of ras 1 located_in IEA UniProt GO_REF:0000044 NCBI chr17:27,456,448...27,626,435
Ensembl chr17:27,456,448...27,626,438 		JBrowse link
G LCP1 lymphocyte cytosolic protein 1 located_in IEA UniProt GO_REF:0000044 NCBI chr13:46,125,923...46,182,177
Ensembl chr13:46,125,920...46,211,871 		JBrowse link
G MACF1 microtubule actin crosslinking factor 1 located_in IDA
IEA		 (PMID:20937854) UniProt PMID:20937854 GO_REF:0000044 NCBI chr 1:39,084,167...39,487,138
Ensembl chr 1:39,081,316...39,487,177 		JBrowse link
G MAP2 microtubule associated protein 2 located_in ISO PMID:11029056 CAFA PMID:11029056 RGD:12793013 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MTMR6 myotubularin related protein 6 located_in IEA UniProt GO_REF:0000044 NCBI chr13:25,246,222...25,287,488
Ensembl chr13:25,246,222...25,287,510 		JBrowse link
G MTMR9 myotubularin related protein 9 located_in IEA UniProt GO_REF:0000044 NCBI chr 8:11,284,816...11,339,526
Ensembl chr 8:11,284,816...11,328,146 		JBrowse link
G MTSS2 MTSS I-BAR domain containing 2 located_in IDA (PMID:20875796) UniProt PMID:20875796 NCBI chr16:70,661,204...70,686,053
Ensembl chr16:70,661,204...70,686,053 		JBrowse link
G MYO1C myosin IC located_in ISO
IEA		 RGD
UniProt		 PMID:22918957 GO_REF:0000044 RGD:11073622 NCBI chr17:1,464,186...1,492,686
Ensembl chr17:1,464,186...1,492,686 		JBrowse link
G MYO6 myosin VI located_in ISO
IEA		 RGD
Ensembl
UniProt		 PMID:9852149 GO_REF:0000044 GO_REF:0000107 RGD:2314969 NCBI chr 6:75,749,239...75,919,537
Ensembl chr 6:75,749,201...75,919,537 		JBrowse link
G NCK1 NCK adaptor protein 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:136,862,208...136,951,606
Ensembl chr 3:136,862,208...136,951,606 		JBrowse link
G NCK2 NCK adaptor protein 2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:105,744,453...105,894,272
Ensembl chr 2:105,744,912...105,894,274 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor located_in IEA UniProt GO_REF:0000044 NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,556...29,698,598 		JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 located_in IDA (PMID:16814409) UniProt PMID:16814409 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428 		JBrowse link
G PACSIN1 protein kinase C and casein kinase substrate in neurons 1 located_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr 6:34,466,076...34,535,223
Ensembl chr 6:34,466,061...34,535,229 		JBrowse link
G PACSIN2 protein kinase C and casein kinase substrate in neurons 2 located_in IEA UniProt GO_REF:0000044 NCBI chr22:42,869,766...43,015,149
Ensembl chr22:42,835,412...43,015,149 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 located_in IEA UniProt GO_REF:0000044 NCBI chr11:77,322,017...77,530,009
Ensembl chr11:77,322,017...77,474,635 		JBrowse link
G PDE4A phosphodiesterase 4A located_in IEA UniProt GO_REF:0000044 NCBI chr19:10,416,773...10,469,631
Ensembl chr19:10,416,773...10,469,630 		JBrowse link
G PDE9A phosphodiesterase 9A located_in IEA UniProt GO_REF:0000044 NCBI chr21:42,653,621...42,775,509
Ensembl chr21:42,653,621...42,775,509 		JBrowse link
G PDPN podoplanin located_in IEA
IDA		 (PMID:17046996) UniProt PMID:17046996 GO_REF:0000044 NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957 		JBrowse link
G PDXP pyridoxal phosphatase located_in IEA
IDA		 (PMID:15580268) UniProt PMID:15580268 GO_REF:0000044 NCBI chr22:37,658,723...37,666,932
Ensembl chr22:37,658,723...37,666,932 		JBrowse link
G PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha located_in IEA
IDA		 (PMID:20660631) Ensembl
UniProt		 PMID:20660631 GO_REF:0000107 NCBI chr 1:151,195,419...151,249,531
Ensembl chr 1:151,197,949...151,249,536 		JBrowse link
G PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma located_in IEA UniProt GO_REF:0000044 NCBI chr19:3,630,183...3,700,468
Ensembl chr19:3,630,183...3,700,468 		JBrowse link
G PLA2G4F phospholipase A2 group IVF located_in
is_active_in		 IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:42,139,034...42,156,636
Ensembl chr15:42,139,034...42,156,636 		JBrowse link
G PLCG1 phospholipase C gamma 1 is_active_in IDA
IBA		 (PMID:11331309) ARUK-UCL
GO_Central		 PMID:11331309 GO_REF:0000033 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801 		JBrowse link
G PLCG2 phospholipase C gamma 2 is_active_in IDA
IBA		 (PMID:11331309) ARUK-UCL
GO_Central		 PMID:11331309 GO_REF:0000033 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G PLEK pleckstrin located_in IDA (PMID:9060471) BHF-UCL PMID:9060471 NCBI chr 2:68,365,282...68,397,453
Ensembl chr 2:68,365,282...68,397,453 		JBrowse link
G PLEKHA1 pleckstrin homology domain containing A1 located_in IDA (PMID:12101241) UniProt PMID:12101241 NCBI chr10:122,374,708...122,442,600
Ensembl chr10:122,374,696...122,432,354 		JBrowse link
G PLEKHO1 pleckstrin homology domain containing O1 located_in
is_active_in		 IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:150,149,646...150,160,065
Ensembl chr 1:150,149,183...150,164,720 		JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B located_in IDA
IEA		 (PMID:19151759) UniProt PMID:19151759 GO_REF:0000044 NCBI chr17:50,133,737...50,150,677
Ensembl chr17:50,133,737...50,150,677 		JBrowse link
G PSD pleckstrin and Sec7 domain containing located_in IEA
IDA		 (PMID:23603394) UniProt PMID:23603394 GO_REF:0000044 NCBI chr10:102,402,619...102,419,946
Ensembl chr10:102,402,617...102,421,539 		JBrowse link
G PSD2 pleckstrin and Sec7 domain containing 2 located_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr 5:139,742,475...139,844,466
Ensembl chr 5:139,795,808...139,844,466 		JBrowse link
G PSD3 pleckstrin and Sec7 domain containing 3 located_in
is_active_in		 IEA
IBA
ISS		 UniProt
GO_Central
TreeGrafter		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000044 GO_REF:0000118 NCBI chr 8:18,527,303...19,084,805
Ensembl chr 8:18,527,303...19,084,730 		JBrowse link
G PSD4 pleckstrin and Sec7 domain containing 4 located_in
is_active_in		 IEA
IBA
IDA		 (PMID:23603394) UniProt
GO_Central
TreeGrafter		 PMID:23603394 GO_REF:0000033 GO_REF:0000044 GO_REF:0000118 NCBI chr 2:113,173,971...113,209,391
Ensembl chr 2:113,157,325...113,209,396 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J located_in IEA UniProt
Ensembl		 GO_REF:0000044 GO_REF:0000107 NCBI chr11:47,980,559...48,170,839
Ensembl chr11:47,980,425...48,170,839 		JBrowse link
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 ISO RGD PMID:11381105 RGD:9589125 NCBI chr 7:121,873,161...122,062,036
Ensembl chr 7:121,873,089...122,062,036 		JBrowse link
G RAB34 RAB34, member RAS oncogene family NOT|located_in IDA (PMID:17881736) UniProt PMID:17881736 NCBI chr17:28,714,281...28,718,428
Ensembl chr17:28,714,281...28,718,429 		JBrowse link
G RAC1 Rac family small GTPase 1 located_in IDA (PMID:20875796) UniProt PMID:20875796 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RASGRP2 RAS guanyl releasing protein 2 located_in IEA UniProt GO_REF:0000044 NCBI chr11:64,726,911...64,745,456
Ensembl chr11:64,726,911...64,745,456 		JBrowse link
G RHOA ras homolog family member A located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G RIGI RNA sensor RIG-I located_in IDA
IEA		 (PMID:19122199) UniProt PMID:19122199 GO_REF:0000044 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208 		JBrowse link
G RPS3 ribosomal protein S3 located_in IDA (PMID:16814409) UniProt PMID:16814409 NCBI chr11:75,399,518...75,422,302
Ensembl chr11:75,399,515...75,422,280 		JBrowse link
G SH2D3C SH2 domain containing 3C located_in IEA UniProt GO_REF:0000044 NCBI chr 9:127,738,317...127,778,666
Ensembl chr 9:127,738,317...127,778,710 		JBrowse link
G SH3BGRL3 SH3 domain binding glutamate rich protein like 3 located_in IMP
IEA		 (PMID:34380438) UniProt PMID:34380438 GO_REF:0000044 NCBI chr 1:26,280,086...26,281,522
Ensembl chr 1:26,280,086...26,281,522 		JBrowse link
G SH3YL1 SH3 and SYLF domain containing 1 located_in
is_active_in		 IDA
IEA
IBA		 (PMID:21624956) MGI
TreeGrafter
GO_Central		 PMID:21624956 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:218,136...264,824
Ensembl chr 2:217,730...266,398 		JBrowse link
G SNTG1 syntrophin gamma 1 located_in IDA (PMID:15485858) UniProt PMID:15485858 NCBI chr 8:49,909,796...50,796,692
Ensembl chr 8:49,909,789...50,796,692 		JBrowse link
G SPATA13 spermatogenesis associated 13 located_in IEA
IDA		 (PMID:19151759) UniProt PMID:19151759 GO_REF:0000044 NCBI chr13:23,979,802...24,307,069
Ensembl chr13:23,979,805...24,307,074
Ensembl chr13:23,979,805...24,307,074 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 located_in IEA UniProt GO_REF:0000044 NCBI chr13:80,335,976...80,341,126
Ensembl chr13:80,335,976...80,341,126 		JBrowse link
G SPRY4 sprouty RTK signaling antagonist 4 located_in IEA UniProt GO_REF:0000044 NCBI chr 5:142,310,430...142,325,021
Ensembl chr 5:142,310,427...142,326,455 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase located_in IEA Ensembl GO_REF:0000107 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SYNJ2 synaptojanin 2 ISO when coexpressed with constitutively GTP-bound Rac1 RGD PMID:11498538 RGD:628465 NCBI chr 6:157,981,296...158,099,176
Ensembl chr 6:157,981,863...158,099,176 		JBrowse link
G TESC tescalcin located_in IEA UniProt GO_REF:0000044 NCBI chr12:117,038,923...117,099,416
Ensembl chr12:117,038,923...117,099,479 		JBrowse link
G THEM4 thioesterase superfamily member 4 located_in IEA UniProt GO_REF:0000044 NCBI chr 1:151,870,866...151,909,511
Ensembl chr 1:151,870,866...151,909,637 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 located_in ISO
IEA		 RGD
Ensembl		 PMID:12446731 GO_REF:0000107 RGD:629540 NCBI chr21:31,118,418...31,559,087
Ensembl chr21:31,118,416...31,559,977 		JBrowse link
G TIRAP TIR domain containing adaptor protein located_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLN1 talin 1 located_in IEA UniProt GO_REF:0000044 NCBI chr 9:35,696,948...35,732,195
Ensembl chr 9:35,696,948...35,732,195 		JBrowse link
G TPM1 tropomyosin 1 located_in IDA (PMID:12686598) BHF-UCL PMID:12686598 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 located_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406 		JBrowse link
G TWF1 twinfilin actin binding protein 1 located_in IEA
ISS		 (PMID:12807912) Ensembl
BHF-UCL		 PMID:12807912 GO_REF:0000107 NCBI chr12:43,793,723...43,806,317
Ensembl chr12:43,793,723...43,806,328 		JBrowse link
G WWC1 WW and C2 domain containing 1 located_in IEA
IDA		 (PMID:18190796) UniProt PMID:18190796 GO_REF:0000044 NCBI chr 5:168,291,645...168,472,303
Ensembl chr 5:168,291,645...168,472,303 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20938
    cellular anatomical entity 20557
      cell leading edge 500
        ruffle 205
          ruffle membrane 110
Path 2
Term Annotations click to browse term
  cellular_component 20938
    cellular anatomical entity 20557
      cell projection 2851
        plasma membrane bounded cell projection 2734
          ruffle 205
            ruffle membrane 110
paths to the root