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ONTOLOGY REPORT - ANNOTATIONS

Term:ruffle
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Accession:GO:0001726 term browser browse the term
Definition:Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
Synonyms:related_synonym: membrane ruffle
 never_in_taxon: NCBITaxon:2 ! Bacteria;   NCBITaxon:33090 ! Viridiplantae;   NCBITaxon:4751 ! Fungi;   NCBITaxon:4890 ! Ascomycota


show annotations for term's descendants           Sort by:
ruffle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase IDA RGD PMID:16831423 RGD:1598670 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Acap2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 located_in ISO
IEA		 (PMID:11062263)
GO_REF:0000107		 RGD
Ensembl		 PMID:11062263 GO_REF:0000107 NCBI chr11:69,538,487...69,654,156
Ensembl chr11:69,538,546...69,654,151 		JBrowse link
G Actn1 actinin, alpha 1 located_in ISO
IEA
ISS		 (PMID:11223950)
GO_REF:0000044
(MGI:3703181|PMID:17298598)
GO_REF:0000024		 RGD
UniProt		 PMID:11223950 PMID:17298598 GO_REF:0000024 GO_REF:0000044 MGI:3703181 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251 		JBrowse link
G Actr3 actin related protein 3 IDA RGD PMID:10209028 RGD:2306208 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Aif1 allograft inflammatory factor 1 located_in ISO (PMID:14756805) RGD PMID:14756805 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 located_in ISO
IEA		 (MGI:3759339|PMID:15033976)
(PMID:15033976)
GO_REF:0000107		 RGD
Ensembl		 PMID:15033976 GO_REF:0000107 MGI:3759339 NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737 		JBrowse link
G Amot angiomotin located_in ISO (PMID:11257124) RGD PMID:11257124 NCBI chr  X:108,982,399...109,041,265
Ensembl chr  X:108,984,022...109,041,272 		JBrowse link
G Anxa2 annexin A2 IDA RGD PMID:19193640 RGD:7242275 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 located_in ISO (MGI:6271154|PMID:25568335)
(PMID:25568335)		 RGD PMID:25568335 MGI:6271154 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 located_in ISO
IEA		 (MGI:6271154|PMID:25568335)
(PMID:25568335)
GO_REF:0000044		 RGD
UniProt		 PMID:25568335 GO_REF:0000044 MGI:6271154 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Arf6 ADP-ribosylation factor 6 is_active_in
located_in		 IDA
IBA
ISO		 GO_REF:0000033
(PMID:9312003)		 GO_Central
RGD		 PMID:9312003 PMID:11950936 GO_REF:0000033, RGD:727254 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114 		JBrowse link
G Arfip2 ADP-ribosylation factor interacting protein 2 located_in ISO (PMID:8670882) RGD PMID:8670882 NCBI chr 1:159,974,255...159,980,398
Ensembl chr 1:159,974,201...159,980,336 		JBrowse link
G Arhgap1 Rho GTPase activating protein 1 located_in ISO (PMID:15860730) RGD PMID:15860730 NCBI chr 3:77,621,377...77,643,400
Ensembl chr 3:77,620,655...77,643,396 		JBrowse link
G Arhgap18 Rho GTPase activating protein 18 part_of ISO (PMID:28251925) RGD PMID:28251925 NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256 		JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697 		JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 located_in
is_active_in		 ISO
IBA		 (PMID:18400762)
GO_REF:0000033		 RGD
GO_Central		 PMID:18400762 GO_REF:0000033 NCBI chr 5:148,433,382...148,476,027
Ensembl chr 5:148,433,494...148,474,073 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 located_in ISO (MGI:5575464|PMID:22467241)
(PMID:22467241)		 RGD PMID:22467241 MGI:5575464 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member located_in ISO
IEA
ISS		 (PMID:9472046)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9472046 GO_REF:0000024 GO_REF:0000107 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 is_active_in ISO (PMID:19116644) RGD PMID:19116644 NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308 		JBrowse link
G Capg capping actin protein, gelsolin like located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 located_in ISO (PMID:26466680), (PMID:26578515) RGD PMID:26466680 PMID:26578515 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965 		JBrowse link
G Cd2ap CD2-associated protein located_in ISO
IEA		 (PMID:10339567)
GO_REF:0000107		 RGD
Ensembl		 PMID:10339567 GO_REF:0000107 NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 located_in ISO (PMID:10205165) RGD PMID:10205165 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Cit citron rho-interacting serine/threonine kinase located_in ISO (PMID:12781320) RGD PMID:12781320 NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860 		JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884 		JBrowse link
G Cobl cordon-bleu WH2 repeat protein located_in
is_active_in		 ISO
IBA
IEA		 (MGI:3765263|PMID:17956734)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:17956734 GO_REF:0000033 GO_REF:0000107 MGI:3765263 NCBI chr14:86,828,137...87,060,682
Ensembl chr14:86,828,139...87,060,800 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 located_in IEA
ISO		 GO_REF:0000107
(PMID:26437238)		 Ensembl
RGD		 PMID:26437238 GO_REF:0000107 NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010 		JBrowse link
G Cttn cortactin located_in ISO
IEA		 (MGI:1353214|PMID:10637315), (MGI:2671745|PMID:12913069)
(PMID:10637315), (PMID:12913069)
GO_REF:0000107		 RGD
Ensembl		 PMID:10637315 PMID:12913069 GO_REF:0000107 MGI:1353214 MGI:2671745 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Cyth2 cytohesin 2 IDA RGD PMID:12032543 RGD:625544 NCBI chr 1:96,283,182...96,291,094
Ensembl chr 1:96,284,252...96,291,092 		JBrowse link
G Cyth3 cytohesin 3 located_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q902B1 (PMID:11445584)		 Ensembl
RGD		 PMID:11445584 GO_REF:0000107 NCBI chr12:10,840,137...10,933,792
Ensembl chr12:10,840,157...10,933,812 		JBrowse link
G Dbnl drebrin-like located_in ISS
ISO		 GO_REF:0000024
(PMID:12913069)
(MGI:2671745|PMID:12913069)		 UniProt
RGD		 PMID:12913069 GO_REF:0000024 MGI:2671745 NCBI chr14:80,666,115...80,681,155
Ensembl chr14:80,666,124...80,681,155 		JBrowse link
G Ezr ezrin located_in ISO (PMID:25554515), (PMID:9852149) RGD PMID:9852149 PMID:25554515 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fgd1 FYVE, RhoGEF and PH domain containing 1 located_in ISO (PMID:12913069) RGD PMID:12913069 NCBI chr  X:20,023,746...20,066,734
Ensembl chr  X:20,023,746...20,066,566 		JBrowse link
G Fgd2 FYVE, RhoGEF and PH domain containing 2 located_in ISO (PMID:18838382) RGD PMID:18838382 NCBI chr20:7,424,795...7,441,603
Ensembl chr20:7,424,790...7,441,603 		JBrowse link
G Frmd4b FERM domain containing 4B located_in ISO PR:O08967 (PMID:11445584) RGD PMID:11445584 NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 is_active_in
located_in		 IDA
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:3525578)		 GO_Central
Ensembl
RGD		 PMID:3525578 PMID:7657718 GO_REF:0000033 GO_REF:0000107, RGD:2317778 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Fscn3 fascin actin-bundling protein 3 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:57,042,797...57,052,224
Ensembl chr 4:57,042,797...57,052,404 		JBrowse link
G Gas7 growth arrest specific 7 located_in ISO (PMID:11795944) RGD PMID:11795944 NCBI chr10:52,152,718...52,383,283
Ensembl chr10:52,152,493...52,383,276 		JBrowse link
G Gnas GNAS complex locus IDA Gnas, Alex RGD PMID:11447126 RGD:5509808 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gsn gelsolin IDA RGD PMID:16280379 RGD:1599859 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E IDA RGD PMID:10405344 RGD:1299274 NCBI chr 3:9,216,776...9,229,539
Ensembl chr 3:9,216,776...9,229,450 		JBrowse link
G Inpp5j inositol polyphosphate-5-phosphatase J is_active_in
located_in		 IDA
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:12536145)		 GO_Central
Ensembl
RGD		 PMID:12536145 PMID:10593988 GO_REF:0000033 GO_REF:0000107, RGD:633686 NCBI chr14:78,374,161...78,385,305
Ensembl chr14:78,374,161...78,385,326 		JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K located_in
is_active_in		 ISO
IBA		 (PMID:12536145)
GO_REF:0000033		 RGD
GO_Central		 PMID:12536145 GO_REF:0000033 NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 located_in ISO (PMID:25554515), (PMID:26242911) RGD PMID:25554515 PMID:26242911 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 located_in
is_active_in		 ISO
IBA		 (PMID:11919189)
(PMID:16741948)
GO_REF:0000033
(MGI:5486556|PMID:16741948)		 RGD
GO_Central		 PMID:11919189 PMID:16741948 GO_REF:0000033 MGI:5486556 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Kif18a kinesin family member 18A located_in ISO (PMID:17006958) RGD PMID:17006958 NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582 		JBrowse link
G Klhl2 kelch-like family member 2 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr16:24,860,744...24,973,348
Ensembl chr16:24,860,667...24,973,341 		JBrowse link
G Klhl41 kelch-like family member 41 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222 		JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein located_in ISO
IEA		 (PMID:26242911)
GO_REF:0000107		 RGD
Ensembl		 PMID:26242911 GO_REF:0000107 NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 located_in ISO (PMID:16636079)
(PMID:14756805)		 RGD PMID:14756805 PMID:16636079 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680 		JBrowse link
G Lima1 LIM domain and actin binding 1 located_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:17875928)
GO_REF:0000107
(MGI:3768577|PMID:17875928)		 UniProt
RGD
Ensembl		 PMID:17875928 GO_REF:0000024 GO_REF:0000107 MGI:3768577 NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973 		JBrowse link
G Mkln1 muskelin 1 located_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:9724633)
GO_REF:0000024
(MGI:1351271|PMID:9724633)		 Ensembl
RGD
UniProt		 PMID:9724633 GO_REF:0000024 GO_REF:0000107 MGI:1351271 NCBI chr 4:59,815,912...60,124,047
Ensembl chr 4:60,002,464...60,123,993 		JBrowse link
G Mtm1 myotubularin 1 located_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000044
(PMID:12118066)		 UniProt
RGD		 PMID:12118066 GO_REF:0000024 GO_REF:0000044 NCBI chr 6:488,923...506,882
Ensembl chr 6:488,969...506,860 		JBrowse link
G Mtmr14 myotubularin related protein 14 located_in ISO (PMID:17008356) RGD PMID:17008356 NCBI chr 4:146,386,949...146,429,990
Ensembl chr 4:146,386,956...146,429,990 		JBrowse link
G Mtss2 MTSS I-BAR domain containing 2 located_in ISO (PMID:18413296) RGD PMID:18413296 NCBI chr19:38,692,793...38,714,575
Ensembl chr19:38,693,194...38,713,507 		JBrowse link
G Myadm myeloid-associated differentiation marker located_in ISO
IEA		 (PMID:21325632)
GO_REF:0000107		 RGD
Ensembl		 PMID:21325632 GO_REF:0000107 NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035 		JBrowse link
G Myh9 myosin, heavy chain 9 located_in ISO
ISS		 (PMID:16403913)
GO_REF:0000024		 RGD
UniProt		 PMID:16403913 GO_REF:0000024 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Myo10 myosin X located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 2:76,100,989...76,305,619
Ensembl chr 2:76,100,987...76,303,030 		JBrowse link
G Myo5a myosin VA located_in ISO
IEA		 (PMID:9852149)
GO_REF:0000107		 RGD
Ensembl		 PMID:9852149 GO_REF:0000107 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Myo6 myosin VI located_in
is_active_in		 ISO
IBA		 (PMID:16507995), (PMID:9852149)
GO_REF:0000033		 RGD
GO_Central		 PMID:9852149 PMID:16507995 GO_REF:0000033 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Myo9b myosin IXb is_active_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:9348541 GO_REF:0000033, RGD:1581711 NCBI chr16:17,945,379...18,030,114
Ensembl chr16:17,945,448...18,030,126 		JBrowse link
G Nckap1 NCK-associated protein 1 located_in ISO (MGI:5897521|PMID:27927633)
(PMID:27927633)		 RGD PMID:27927633 MGI:5897521 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor located_in IEA
ISO		 GO_REF:0000107
(PMID:9563848)		 Ensembl
RGD		 PMID:9563848 GO_REF:0000107 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 located_in ISS
ISO		 GO_REF:0000024
(PMID:11919189)		 HGNC-UCL
RGD		 PMID:11919189 GO_REF:0000024 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538 		JBrowse link
G Notch1 notch receptor 1 located_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 located_in IDA
ISO
ISS		 (PMID:12912914)
GO_REF:0000024		 RGD
UniProt		 PMID:12912914 PMID:19574218 GO_REF:0000024, RGD:11533928 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Palld palladin, cytoskeletal associated protein IDA RGD PMID:16868024 RGD:2325783 NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta located_in ISO (PMID:26437238) RGD PMID:26437238 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pdlim7 PDZ and LIM domain 7 located_in IEA
ISO		 GO_REF:0000107
(PMID:15946664)		 Ensembl
RGD		 PMID:15946664 GO_REF:0000107 NCBI chr17:9,124,565...9,139,814
Ensembl chr17:9,124,649...9,139,811 		JBrowse link
G Pdpn podoplanin located_in ISS
ISO		 GO_REF:0000024
(MGI:1351508|PMID:10574709)		 UniProt
RGD		 PMID:10574709 GO_REF:0000024 MGI:1351508 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA RGD PMID:9148965 RGD:11541088 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Plcg1 phospholipase C, gamma 1 located_in ISO
ISS		 (PMID:17229814)
GO_REF:0000024		 RGD
UniProt		 PMID:17229814 GO_REF:0000024 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Podxl podocalyxin-like located_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000044
(PMID:18456258)		 UniProt
RGD		 PMID:18456258 GO_REF:0000024 GO_REF:0000044 NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899 		JBrowse link
G Ptk6 protein tyrosine kinase 6 located_in ISO (PMID:15572663) RGD PMID:15572663 NCBI chr 3:168,307,073...168,315,664
Ensembl chr 3:168,307,073...168,315,664 		JBrowse link
G Rab34 RAB34, member RAS oncogene family located_in ISO (PMID:12446704) RGD PMID:12446704 NCBI chr10:63,083,319...63,087,538
Ensembl chr10:63,083,338...63,087,538 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family located_in ISO (PMID:12446704), (PMID:21419809) RGD PMID:12446704 PMID:21419809 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873 		JBrowse link
G Rasa1 RAS p21 protein activator 1 located_in IEA
ISO		 GO_REF:0000107
(PMID:15860730)		 Ensembl
RGD		 PMID:15860730 GO_REF:0000107 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854 		JBrowse link
G Rdx radixin located_in ISO (PMID:9563848) RGD PMID:9563848 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678 		JBrowse link
G Rinl Ras and Rab interactor-like located_in ISO (PMID:21419809) RGD PMID:21419809 NCBI chr 1:84,077,011...84,088,590
Ensembl chr 1:84,077,265...84,088,330 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 located_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:16741948)
GO_REF:0000044
(MGI:5486556|PMID:16741948)		 UniProt
RGD		 PMID:16741948 GO_REF:0000024 GO_REF:0000044 MGI:5486556 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G S100a11 S100 calcium binding protein A11 located_in ISO (PMID:10913138) RGD PMID:10913138 NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044 		JBrowse link
G S100a6 S100 calcium binding protein A6 located_in ISO (PMID:10913138) RGD PMID:10913138 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180 		JBrowse link
G S100b S100 calcium binding protein B located_in ISO (PMID:10913138) RGD PMID:10913138 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein located_in ISO (MGI:5913054|PMID:28098138)
(PMID:28098138)		 RGD PMID:28098138 MGI:5913054 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 located_in ISO (PMID:15946664) RGD PMID:15946664 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Snx5 sorting nexin 5 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 3:131,621,875...131,641,127
Ensembl chr 3:131,621,880...131,641,192 		JBrowse link
G Tesc tescalcin located_in ISO (MGI:3688373|PMID:14661968)
(PMID:14661968)		 RGD PMID:14661968 MGI:3688373 NCBI chr12:38,521,832...38,555,665
Ensembl chr12:38,521,861...38,555,824 		JBrowse link
G Tln1 talin 1 located_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:57,787,670...57,817,900
Ensembl chr 5:57,787,943...57,817,900 		JBrowse link
G Tln2 talin 2 located_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:67,830,920...68,252,240
Ensembl chr 8:67,834,326...68,252,219 		JBrowse link
G Tlr4 toll-like receptor 4 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tmem87a transmembrane protein 87A located_in ISO (PMID:32228863) RGD PMID:32228863 NCBI chr 3:107,307,726...107,353,571
Ensembl chr 3:107,307,726...107,353,551 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A located_in ISO (PMID:14573547) RGD PMID:14573547 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Trpm7 transient receptor potential cation channel, subfamily M, member 7 located_in IEA
ISO		 GO_REF:0000107
(PMID:16407977)		 Ensembl
RGD		 PMID:16407977 GO_REF:0000107 NCBI chr 3:114,046,258...114,134,799
Ensembl chr 3:114,046,258...114,135,190 		JBrowse link
G Vil1 villin 1 located_in ISO (PMID:15342783), (PMID:17229814), (PMID:17606613) RGD PMID:15342783 PMID:17229814 PMID:17606613 NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858 		JBrowse link
G Wasf2 WASP family member 2 located_in ISO (PMID:12446704) RGD PMID:12446704 NCBI chr 5:145,336,817...145,402,041
Ensembl chr 5:145,336,842...145,399,242 		JBrowse link
G Wipf1 WAS/WASL interacting protein family, member 1 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 3:58,314,521...58,416,668
Ensembl chr 3:58,314,542...58,372,742 		JBrowse link
ruffle membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 located_in ISS
ISO		 GO_REF:0000024
(MGI:3662940|PMID:16908670)
(PMID:16908670)		 Alzheimers_University_of_Toronto
RGD		 PMID:16908670 GO_REF:0000024 MGI:3662940 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 located_in IEA
ISO		 GO_REF:0000107
(PMID:14970227)		 Ensembl
RGD		 PMID:14970227 GO_REF:0000107 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Aif1 allograft inflammatory factor 1 located_in IEA
ISO
ISS
IBA		 GO_REF:0000044
(MGI:5315376|PMID:10934045)
GO_REF:0000024
(PMID:18699778)
GO_REF:0000033
(PMID:10934045)		 UniProt
RGD
GO_Central		 PMID:10934045 PMID:18699778 GO_REF:0000024 GO_REF:0000033 GO_REF:0000044 MGI:5315376 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Aif1l allograft inflammatory factor 1-like located_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:15,229,476...15,254,033
Ensembl chr 3:15,229,524...15,254,023 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 located_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5292403|PMID:21907143)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21907143 GO_REF:0000024 GO_REF:0000107 MGI:5292403 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Apc APC regulator of WNT signaling pathway located_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19151759)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19151759 GO_REF:0000024 GO_REF:0000107 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 located_in ISO (MGI:6270783|PMID:27219021)
(PMID:27219021)		 RGD PMID:27219021 MGI:6270783 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Arf4 ADP-ribosylation factor 4 located_in ISO
IEA		 (PMID:12446727)
GO_REF:0000107		 RGD
Ensembl		 PMID:12446727 GO_REF:0000107 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 located_in
is_active_in		 ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:19043560)
GO_REF:0000107
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:19043560 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 IDA RGD PMID:17224451 RGD:2306207 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471 		JBrowse link
G Bmx BMX non-receptor tyrosine kinase located_in ISO (PMID:11331870) RGD PMID:11331870 NCBI chr  X:30,227,251...30,290,015
Ensembl chr  X:30,227,251...30,289,993 		JBrowse link
G C2cd5 C2 calcium-dependent domain containing 5 located_in ISO (PMID:21907143) RGD PMID:21907143 NCBI chr 4:175,969,544...176,055,597
Ensembl chr 4:175,969,545...176,055,558 		JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone IDA RGD PMID:16335536 RGD:5131523 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809 		JBrowse link
G Cdkl5 cyclin-dependent kinase-like 5 located_in IDA PMID:20861382 BHF-UCL PMID:20861382 RGD:8554575 NCBI chr  X:33,757,605...33,988,075
Ensembl chr  X:33,821,257...33,986,582 		JBrowse link
G Cfl1 cofilin 1 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Cfl1l1 cofilin 1 like 1 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 8:108,489,949...108,491,597 JBrowse link
G Cib1 calcium and integrin binding 1 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 located_in IDA
ISS
ISO		 MMO:0000686
GO_REF:0000024
(PMID:20937854)		 UniProt
RGD		 PMID:20937854 PMID:22992739 GO_REF:0000024, RGD:28912745 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731 		JBrowse link
G Diaph1 diaphanous-related formin 1 located_in ISO (PMID:9214622) RGD PMID:9214622 NCBI chr18:29,669,659...29,769,070
Ensembl chr18:29,669,659...29,769,172 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein located_in ISO
IEA		 (PMID:19158340)
GO_REF:0000107		 RGD
Ensembl		 PMID:19158340 GO_REF:0000107 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Dnm2 dynamin 2 IDA RGD PMID:9725914 RGD:9685132 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 located_in ISO (PMID:19158340) RGD PMID:19158340 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Egfr epidermal growth factor receptor is_active_in ISO (PMID:11331309) RGD PMID:11331309 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G ENSRNOG00000066376 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 Ensembl chr 9:78,433,146...78,434,143 JBrowse link
G ENSRNOG00000070567 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 Ensembl chr 1:187,296,520...187,297,219 JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 located_in ISO (PMID:18794329) RGD PMID:18794329 NCBI chr13:30,670,792...30,770,213
Ensembl chr13:30,669,764...30,768,360 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor located_in
is_active_in		 ISS
ISO
IEA
IBA		 GO_REF:0000024
(MGI:5486573|PMID:11524436)
GO_REF:0000107
GO_REF:0000033
(PMID:11524436)		 UniProt
RGD
Ensembl
GO_Central		 PMID:11524436 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5486573 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873 		JBrowse link
G Eps8l1 EPS8-like 1 located_in
is_active_in		 ISO
IBA		 (PMID:14565974)
GO_REF:0000033		 RGD
GO_Central		 PMID:14565974 GO_REF:0000033 NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524 		JBrowse link
G Eps8l2 EPS8-like 2 located_in
is_active_in		 ISO
IBA		 (PMID:14565974)
GO_REF:0000033		 RGD
GO_Central		 PMID:14565974 GO_REF:0000033 NCBI chr 1:196,446,260...196,471,544
Ensembl chr 1:196,446,287...196,471,541 		JBrowse link
G Eps8l3 EPS8 like 3 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:195,514,692...195,528,085
Ensembl chr 2:195,514,692...195,528,085 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Ezr ezrin located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fam107a family with sequence similarity 107, member A located_in ISO
ISS
IEA		 (PMID:20543869)
GO_REF:0000024
GO_REF:0000044		 RGD
UniProt		 PMID:20543869 GO_REF:0000024 GO_REF:0000044 NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase located_in ISS
ISO		 GO_REF:0000024
(MGI:3513574|PMID:15561106)
(PMID:15561106)		 UniProt
RGD		 PMID:15561106 GO_REF:0000024 MGI:3513574 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326 		JBrowse link
G Hip1r huntingtin interacting protein 1 related located_in ISO (PMID:14732715) RGD PMID:14732715 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734 		JBrowse link
G Inpp5j inositol polyphosphate-5-phosphatase J located_in IDA PMID:10593988 MGI PMID:10593988 RGD:633686 NCBI chr14:78,374,161...78,385,305
Ensembl chr14:78,374,161...78,385,326 		JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K located_in ISO (PMID:12556481) RGD PMID:12556481 NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
G Itga5 integrin subunit alpha 5 located_in ISO (PMID:14970227) RGD PMID:14970227 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837 		JBrowse link
G Itgav integrin subunit alpha V located_in ISO (PMID:25063885) RGD PMID:25063885 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb1 integrin subunit beta 1 located_in IEA
ISO		 GO_REF:0000044
(PMID:14970227)		 UniProt
RGD		 PMID:14970227 GO_REF:0000044 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb3 integrin subunit beta 3 located_in ISO
IEA		 (PMID:25063885)
GO_REF:0000107		 RGD
Ensembl		 PMID:25063885 GO_REF:0000107 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Jcad junctional cadherin 5 associated located_in
is_active_in		 ISO
IBA		 (PMID:28705794)
GO_REF:0000033		 RGD
GO_Central		 PMID:28705794 GO_REF:0000033 NCBI chr17:53,089,382...53,130,996
Ensembl chr17:53,089,382...53,130,967 		JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 located_in ISO (PMID:19559006) RGD PMID:19559006 NCBI chr 1:222,877,962...223,074,514
Ensembl chr 1:222,877,622...223,074,514 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 located_in ISO
IEA		 (PMID:24591580)
GO_REF:0000107
GO_REF:0000044		 RGD
Ensembl
UniProt		 PMID:24591580 GO_REF:0000044 GO_REF:0000107 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G LOC102555366 cofilin-1-like located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr10:54,673,122...54,675,094 JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 located_in ISO
ISS		 (PMID:20937854)
GO_REF:0000024		 RGD
UniProt		 PMID:20937854 GO_REF:0000024 NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905 		JBrowse link
G Map2 microtubule-associated protein 2 located_in IMP PMID:11029056 CAFA PMID:11029056 RGD:12793013 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Mtmr6 myotubularin related protein 6 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr15:34,419,931...34,457,863
Ensembl chr15:34,419,903...34,457,861 		JBrowse link
G Mtss2 MTSS I-BAR domain containing 2 located_in ISO (PMID:20875796) RGD PMID:20875796 NCBI chr19:38,692,793...38,714,575
Ensembl chr19:38,693,194...38,713,507 		JBrowse link
G Myo1c myosin 1C IDA RGD PMID:22918957 RGD:11073622 NCBI chr10:60,498,372...60,520,752
Ensembl chr10:60,498,280...60,520,752 		JBrowse link
G Myo6 myosin VI IDA RGD PMID:9852149 RGD:2314969 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 located_in ISO (PMID:16814409) RGD PMID:16814409 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408 		JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 located_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:4454229|PMID:20404169)
GO_REF:0000107
(PMID:20404169)		 UniProt
RGD
Ensembl		 PMID:20404169 GO_REF:0000024 GO_REF:0000107 MGI:4454229 NCBI chr20:5,718,134...5,768,064
Ensembl chr20:5,719,857...5,765,313 		JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 7:114,505,525...114,599,087
Ensembl chr 7:114,505,152...114,598,546 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Pde9a phosphodiesterase 9A located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr20:9,469,809...9,562,949
Ensembl chr20:9,469,848...9,562,948 		JBrowse link
G Pdpn podoplanin located_in ISO
ISS		 (PMID:17046996)
GO_REF:0000024		 RGD
UniProt		 PMID:17046996 GO_REF:0000024 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
G Pdxp pyridoxal phosphatase located_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:15580268)		 Ensembl
UniProt
RGD		 PMID:15580268 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:110,472,515...110,477,963
Ensembl chr 7:110,472,515...110,477,963 		JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha located_in ISO
IEA		 (PMID:20660631)
GO_REF:0000107
(PMID:15870270)		 RGD
Ensembl		 PMID:15870270 PMID:20660631 GO_REF:0000107 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598 		JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988 		JBrowse link
G Pla2g4f phospholipase A2, group IVF is_active_in
located_in		 IBA
ISO		 GO_REF:0000033
(PMID:17293613)		 GO_Central
RGD		 PMID:17293613 GO_REF:0000033 NCBI chr 3:107,249,053...107,266,201
Ensembl chr 3:107,250,075...107,264,689 		JBrowse link
G Plcg1 phospholipase C, gamma 1 is_active_in
located_in		 ISO
IEA
IBA		 (PMID:11331309)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:11331309 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Plcg2 phospholipase C, gamma 2 located_in
is_active_in		 IEA
ISO
IBA		 GO_REF:0000107
(PMID:11331309)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:11331309 GO_REF:0000033 GO_REF:0000107 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Plek pleckstrin located_in ISO (PMID:9060471) RGD PMID:9060471 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Plekha1 pleckstrin homology domain containing A1 located_in ISO (PMID:12101241) RGD PMID:12101241 NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156 		JBrowse link
G Plekho1 pleckstrin homology domain containing O1 located_in
is_active_in		 IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:22553210)		 Ensembl
GO_Central
RGD		 PMID:22553210 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:183,544,487...183,552,928
Ensembl chr 2:183,544,499...183,552,785 		JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B located_in ISS
ISO		 GO_REF:0000024
(PMID:19151759)		 UniProt
RGD		 PMID:19151759 GO_REF:0000024 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083 		JBrowse link
G Psd pleckstrin and Sec7 domain containing located_in ISO
ISS
IEA		 (PMID:23603394)
GO_REF:0000024
GO_REF:0000044		 RGD
UniProt		 PMID:23603394 GO_REF:0000024 GO_REF:0000044 NCBI chr 1:245,173,279...245,188,681
Ensembl chr 1:245,173,279...245,189,356 		JBrowse link
G Psd2 pleckstrin and Sec7 domain containing 2 located_in ISO (MGI:5897544|PMID:23603394) RGD PMID:23603394 MGI:5897544 NCBI chr18:27,564,912...27,616,674
Ensembl chr18:27,565,587...27,616,672 		JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 located_in
is_active_in		 ISO
IBA		 (MGI:5897544|PMID:23603394)
GO_REF:0000033
(PMID:23603394)		 RGD
GO_Central		 PMID:23603394 GO_REF:0000033 MGI:5897544 NCBI chr16:21,465,643...22,035,846
Ensembl chr16:21,465,639...22,034,547 		JBrowse link
G Psd4 pleckstrin and Sec7 domain containing 4 located_in
is_active_in		 ISO
IBA		 (PMID:23603394)
GO_REF:0000033		 RGD
GO_Central		 PMID:23603394 GO_REF:0000033 NCBI chr 3:7,137,069...7,173,571
Ensembl chr 3:7,137,155...7,173,571 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J located_in ISO (MGI:3850609|PMID:19268662)
(PMID:19268662)		 RGD PMID:19268662 MGI:3850609 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 IDA RGD PMID:11381105 RGD:9589125 NCBI chr 4:51,397,316...51,595,220
Ensembl chr 4:51,397,601...51,595,218 		JBrowse link
G Rab34 RAB34, member RAS oncogene family NOT|located_in ISO (PMID:17881736) RGD PMID:17881736 NCBI chr10:63,083,319...63,087,538
Ensembl chr10:63,083,338...63,087,538 		JBrowse link
G Rac1 Rac family small GTPase 1 located_in ISO
IEA		 (PMID:20875796)
(MGI:5315376|PMID:10934045)
GO_REF:0000107
(PMID:10934045)		 RGD
Ensembl		 PMID:10934045 PMID:20875796 GO_REF:0000107 MGI:5315376 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rasgrp2 RAS guanyl releasing protein 2 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:203,705,777...203,722,993
Ensembl chr 1:203,707,481...203,722,993 		JBrowse link
G Rhoa ras homolog family member A located_in ISO (PMID:9214622) RGD PMID:9214622 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rig1 RNA sensor RIG-1 located_in ISO (PMID:19122199) RGD PMID:19122199 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Rps3 ribosomal protein S3 located_in ISO (PMID:16814409) RGD PMID:16814409 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Sh3bgrl3 SH3 domain binding glutamate-rich protein like 3 located_in ISO
IEA		 (PMID:34380438)
GO_REF:0000044		 RGD
UniProt		 PMID:34380438 GO_REF:0000044 NCBI chr 5:146,354,152...146,355,525
Ensembl chr 5:146,354,152...146,355,331 		JBrowse link
G Sh3yl1 SH3 and SYLF domain containing 1 located_in
is_active_in		 ISO
IEA
IBA		 (PMID:21624956)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21624956 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:47,522,098...47,565,858
Ensembl chr 6:47,522,091...47,565,858 		JBrowse link
G Sntg1 syntrophin, gamma 1 located_in ISO (PMID:15485858) RGD PMID:15485858 NCBI chr 5:9,980,550...10,794,666
Ensembl chr 5:9,981,115...10,791,181 		JBrowse link
G Spata13 spermatogenesis associated 13 located_in ISO (PMID:19151759) RGD PMID:19151759 NCBI chr15:34,778,479...34,907,645
Ensembl chr15:34,778,473...34,905,114 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase located_in ISO (PMID:17623777) RGD PMID:17623777 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Synj2 synaptojanin 2 IDA when coexpressed with constitutively GTP-bound Rac1 RGD PMID:11498538 RGD:628465 NCBI chr 1:46,518,594...46,621,919
Ensembl chr 1:46,518,709...46,633,687 		JBrowse link
G Synj2_v1 synaptojanin 2, variant 1 IDA when coexpressed with constitutively GTP-bound Rac1 RGD PMID:11498538 RGD:628465
G Synj2_v2 synaptojanin 2, variant 2 IDA when coexpressed with constitutively GTP-bound Rac1 RGD PMID:11498538 RGD:628465
G Synj2_v3 synaptojanin 2, variant 3 IDA when coexpressed with constitutively GTP-bound Rac1 RGD PMID:11498538 RGD:628465
G Tesc tescalcin located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr12:38,521,832...38,555,665
Ensembl chr12:38,521,861...38,555,824 		JBrowse link
G Tescl tescalcin-like located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:79,896,554...79,920,998
Ensembl chr 1:79,920,075...79,920,985 		JBrowse link
G Them4 thioesterase superfamily member 4 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 2:181,953,550...181,974,708
Ensembl chr 2:181,953,550...181,974,708 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 IDA RGD PMID:12446731 RGD:629540 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901 		JBrowse link
G Tirap TIR domain containing adaptor protein located_in ISO (MGI:4948831|PMID:16751103) RGD PMID:16751103 MGI:4948831 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tpm1 tropomyosin 1 located_in ISO
IEA		 (PMID:12686598)
GO_REF:0000107		 RGD
Ensembl		 PMID:12686598 GO_REF:0000107 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 located_in IDA PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 located_in ISO (MGI:2673741|PMID:12807912)
(PMID:12807912)		 RGD PMID:12807912 MGI:2673741 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894 		JBrowse link
G Wwc1 WW and C2 domain containing 1 located_in ISO (PMID:18190796) RGD PMID:18190796 NCBI chr10:20,300,735...20,454,393
Ensembl chr10:20,300,833...20,454,497 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20814
    cellular anatomical structure 20574
      cell leading edge 461
        ruffle 185
          ruffle membrane 98
Path 2
Term Annotations click to browse term
  cellular_component 20814
    cellular anatomical structure 20574
      cell projection 2649
        plasma membrane bounded cell projection 2564
          ruffle 185
            ruffle membrane 98
paths to the root