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ONTOLOGY REPORT - ANNOTATIONS


Term:endodermal cell fate specification
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Accession:GO:0001714 term browser browse the term
Definition:The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
Synonyms:exact_synonym: endoderm cell fate specification


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endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:4887279|PMID:21245162)
GO_Central
MGI
PMID:21245162 PMID:21873635 MGI:4887279 NCBI chr23:16,476,498...16,512,406
Ensembl chr23:16,506,032...16,511,527
JBrowse link
G HNF1B HNF1 homeobox B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3807614|PMID:18635606) Ensembl
MGI
PMID:18635606 GO_REF:0000107 MGI:3807614 NCBI chr 9:37,437,992...37,493,200
Ensembl chr 9:37,438,583...37,492,993
JBrowse link
G NANOG Nanog homeobox involved_in ISO (PMID:20713518) MGI PMID:20713518 NCBI chr27:37,262,558...37,266,449 JBrowse link
G SOX17 SRY-box transcription factor 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:5,979,092...5,981,504
Ensembl chr29:5,979,261...5,981,124
JBrowse link
G SOX2 SRY-box transcription factor 2 involved_in ISO (PMID:21245162) MGI PMID:21245162 NCBI chr34:14,853,000...14,855,153 JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,738,333...52,739,962
Ensembl chr 3:52,738,366...52,739,755
JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:35,697,428...35,701,596
Ensembl chr26:35,697,618...35,701,496
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16213
    developmental process 6402
      cellular developmental process 4218
        cell fate specification 100
          endodermal cell fate specification 7
            negative regulation of endodermal cell fate specification 1
            regulation of endodermal cell fate specification + 2
            transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 16213
    developmental process 6402
      anatomical structure development 5947
        multicellular organism development 5432
          embryo development 1272
            embryonic morphogenesis 671
              gastrulation 195
                formation of primary germ layer 129
                  endoderm formation 57
                    endodermal cell differentiation 47
                      endodermal cell fate commitment 15
                        endodermal cell fate specification 7
                          negative regulation of endodermal cell fate specification 1
                          regulation of endodermal cell fate specification + 2
                          transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification 0
paths to the root