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ONTOLOGY REPORT - ANNOTATIONS


Term:endodermal cell fate commitment
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Accession:GO:0001711 term browser browse the term
Definition:The cell differentiation process that results in commitment of a cell to become part of the endoderm.
Synonyms:exact_synonym: endoderm cell fate commitment


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endodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc73 cell division cycle 73 involved_in ISO (MGI:3849235|PMID:19345177) UniProt PMID:19345177 MGI:3849235 NCBI chrNW_004936638:1,365,457...1,482,497 JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO (MGI:3625553|PMID:12194849) MGI PMID:12194849 MGI:3625553 NCBI chrNW_004936473:29,999,542...30,034,610 JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component involved_in ISO (MGI:3849235|PMID:19345177) UniProt PMID:19345177 MGI:3849235 NCBI chrNW_004936528:7,585,937...7,613,022 JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component involved_in ISO (MGI:3849235|PMID:19345177) UniProt PMID:19345177 MGI:3849235 NCBI chrNW_004936471:13,753,061...13,783,990 JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component involved_in ISO (MGI:3849235|PMID:19345177) UniProt PMID:19345177 MGI:3849235 NCBI chrNW_004936661:2,236,121...2,241,086 JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (MGI:1355046|PMID:10742100) MGI PMID:10742100 MGI:1355046 NCBI chrNW_004936837:827,568...838,933 JBrowse link
G Rtf1 RTF1 homolog, Paf1/RNA polymerase II complex component involved_in ISO (MGI:3849235|PMID:19345177) UniProt PMID:19345177 MGI:3849235 NCBI chrNW_004936471:4,770,060...4,829,562 JBrowse link
endodermal cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 acts_upstream_of_or_within ISO (MGI:4442295|PMID:20308546) MGI PMID:20308546 MGI:4442295 NCBI chrNW_004936550:1,814,336...1,844,399 JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO (MGI:4442295|PMID:20308546) MGI PMID:20308546 MGI:4442295 NCBI chrNW_004936496:1,248,582...1,251,406 JBrowse link
endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin acts_upstream_of_or_within ISO (MGI:4887279|PMID:21245162) MGI PMID:21245162 MGI:4887279 NCBI chrNW_004936473:18,825,969...18,833,179 JBrowse link
G Hnf1b HNF1 homeobox B acts_upstream_of_or_within ISO (MGI:3807614|PMID:18635606) MGI PMID:18635606 MGI:3807614 NCBI chrNW_004936490:649,551...702,448 JBrowse link
G Nanog Nanog homeobox acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518 NCBI chrNW_004936892:181,834...187,691 JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518 NCBI chrNW_004936837:827,568...838,933 JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO (MGI:4946573|PMID:21305474) BHF-UCL PMID:21305474 MGI:4946573 NCBI chrNW_004936496:1,248,582...1,251,406 JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:21245162) MGI PMID:21245162 NCBI chrNW_004936566:1,630,698...1,632,607 JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) BHF-UCL PMID:18593560 MGI:4441249 NCBI chrNW_004936483:15,533,264...15,534,576 JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) BHF-UCL PMID:20559569 NCBI chrNW_004936787:307,290...309,963 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12130
    developmental process 5716
      cellular developmental process 3715
        cell fate commitment 245
          cell fate commitment involved in formation of primary germ layer 31
            endodermal cell fate commitment 15
              endodermal cell fate determination 2
              endodermal cell fate specification + 8
Path 2
Term Annotations click to browse term
  biological_process 12130
    developmental process 5716
      anatomical structure development 5344
        multicellular organism development 4894
          embryo development 1183
            embryonic morphogenesis 637
              gastrulation 179
                formation of primary germ layer 117
                  endoderm formation 52
                    endodermal cell differentiation 46
                      endodermal cell fate commitment 15
                        endodermal cell fate determination 2
                        endodermal cell fate specification + 8
paths to the root