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ONTOLOGY REPORT - ANNOTATIONS

Term:mesodermal cell fate commitment
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Accession:GO:0001710 term browser browse the term
Definition:The cell differentiation process that results in commitment of a cell to become part of the mesoderm.
Synonyms:exact_synonym: mesoderm cell fate commitment

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show annotations for term's descendants           Sort by:
mesodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nanog Nanog homeobox acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:16801560) MGI PMID:16801560 NCBI chrNW_004624860:5,026,203...5,037,219 JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:10742100) MGI PMID:10742100 NCBI chrNW_004624754:24,758,055...24,764,723 JBrowse link
G Smad1 SMAD family member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16801560) MGI
Ensembl		 PMID:16801560 GO_REF:0000107 NCBI chrNW_004624853:4,415,816...4,503,317
Ensembl chrNW_004624853:4,444,876...4,502,496 		JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO (PMID:14511481) MGI PMID:14511481 NCBI chrNW_004624754:4,557,407...4,564,580
Ensembl chrNW_004624754:4,557,952...4,564,644 		JBrowse link
mesodermal cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO (PMID:7657163) MGI PMID:7657163 NCBI chrNW_004624731:15,262,480...15,269,196
Ensembl chrNW_004624731:15,263,274...15,269,743 		JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chrNW_004624744:19,782,174...19,975,496
Ensembl chrNW_004624744:19,782,790...19,977,335 		JBrowse link
G Hoxa11 homeobox A11 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chrNW_004624739:3,420,501...3,424,151
Ensembl chrNW_004624739:3,418,723...3,423,950 		JBrowse link
G Pax2 paired box 2 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chrNW_004624831:375,851...453,968
Ensembl chrNW_004624831:375,866...453,930 		JBrowse link
G Sfrp2 secreted frizzled related protein 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chrNW_004624858:5,052,736...5,061,495
Ensembl chrNW_004624858:5,052,518...5,061,591 		JBrowse link
G Six2 SIX homeobox 2 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chrNW_004624738:26,442,935...26,447,100
Ensembl chrNW_004624738:26,442,965...26,446,942 		JBrowse link
G Tbx6 T-box transcription factor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9490412) Ensembl
MGI		 PMID:9490412 GO_REF:0000107 NCBI chrNW_004624782:13,169,096...13,174,498
Ensembl chrNW_004624782:13,169,719...13,174,056 		JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624791:11,313,139...11,316,998
Ensembl chrNW_004624791:11,313,142...11,315,982 		JBrowse link
G Sfrp2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chrNW_004624858:5,052,736...5,061,495
Ensembl chrNW_004624858:5,052,518...5,061,591 		JBrowse link
paraxial mesodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO (PMID:9106663) MGI PMID:9106663 NCBI chrNW_004624746:2,632,547...2,634,867
Ensembl chrNW_004624746:2,632,619...2,634,085 		JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO (PMID:9126297) MGI PMID:9126297 NCBI chrNW_004624937:816,752...845,866
Ensembl chrNW_004624937:816,759...845,458 		JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:20559569) BHF-UCL PMID:20559569 NCBI chrNW_004624937:816,752...845,866
Ensembl chrNW_004624937:816,759...845,458 		JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO (PMID:16943278) MGI PMID:16943278 NCBI chrNW_004624841:218,642...304,744
Ensembl chrNW_004624841:219,133...265,397 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (PMID:16943278) MGI PMID:16943278 NCBI chrNW_004624780:5,161,245...5,212,641
Ensembl chrNW_004624780:5,161,073...5,213,870 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15172
    cellular process 14790
      cellular developmental process 4181
        cell differentiation 4180
          mesodermal cell differentiation 31
            mesodermal cell fate commitment 16
              axial mesodermal cell fate commitment + 1
              intermediate mesodermal cell fate commitment + 0
              lateral mesodermal cell fate commitment + 2
              mesodermal cell fate determination + 1
              mesodermal cell fate specification + 11
              paraxial mesodermal cell fate commitment + 2
Path 2
Term Annotations click to browse term
  biological_process 15172
    developmental process 6226
      anatomical structure development 5855
        multicellular organism development 4746
          embryo development 1251
            embryonic morphogenesis 667
              gastrulation 195
                formation of primary germ layer 128
                  mesoderm formation 72
                    mesodermal cell differentiation 31
                      mesodermal cell fate commitment 16
                        axial mesodermal cell fate commitment + 1
                        intermediate mesodermal cell fate commitment + 0
                        lateral mesodermal cell fate commitment + 2
                        mesodermal cell fate determination + 1
                        mesodermal cell fate specification + 11
                        paraxial mesodermal cell fate commitment + 2
paths to the root