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ONTOLOGY REPORT - ANNOTATIONS

Term:mesodermal cell fate commitment
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Accession:GO:0001710 term browser browse the term
Definition:The cell differentiation process that results in commitment of a cell to become part of the mesoderm.
Synonyms:exact_synonym: mesoderm cell fate commitment

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show annotations for term's descendants           Sort by:
mesodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NANOG Nanog homeobox acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:16801560) MGI PMID:16801560 NCBI chr11:7,813,309...7,820,009 JBrowse link
G POU5F1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:10742100) MGI PMID:10742100 NCBI chr17:41,306,523...41,313,065 JBrowse link
G POU5F1 POU class 5 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr17:41,311,005...41,315,373 JBrowse link
G SMAD1 SMAD family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16801560) Ensembl
MGI		 PMID:16801560 GO_REF:0000107 NCBI chr 7:92,047,273...92,123,451
Ensembl chr 7:92,079,914...92,123,429 		JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NODAL nodal growth differentiation factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14511481) MGI
Ensembl		 PMID:14511481 GO_REF:0000107 NCBI chr 9:60,852,567...60,863,225
Ensembl chr 9:60,853,763...60,862,839 		JBrowse link
mesodermal cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:7657163) MGI
Ensembl		 PMID:7657163 GO_REF:0000107 NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225 		JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EYA1 EYA transcriptional coactivator and phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:66,902,961...67,238,149
Ensembl chr 8:66,902,972...67,060,567 		JBrowse link
G HOXA11 homeobox A11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:31,180,232...31,187,709
Ensembl chr21:31,183,682...31,186,010 		JBrowse link
G LOC103216393 paired box protein Pax-2 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chr 9:93,763,975...93,847,180 JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:17462603) MGI
Ensembl		 PMID:17462603 GO_REF:0000107 NCBI chr 7:100,336,442...100,345,093
Ensembl chr 7:100,336,119...100,345,086 		JBrowse link
G SIX2 SIX homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:62,212,920...62,219,976
Ensembl chr14:62,213,115...62,220,069 		JBrowse link
G TBX6 T-box transcription factor 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9490412) MGI
Ensembl		 PMID:9490412 GO_REF:0000107 NCBI chr 5:26,566,673...26,573,258
Ensembl chr 5:26,567,700...26,572,820 		JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:78,836,803...78,840,158
Ensembl chr 9:78,835,162...78,840,146 		JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:8,286,551...8,288,777
Ensembl chr29:8,286,828...8,287,918 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17462603) MGI
Ensembl		 PMID:17462603 GO_REF:0000107 NCBI chr 7:100,336,442...100,345,093
Ensembl chr 7:100,336,119...100,345,086 		JBrowse link
paraxial mesodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXC2 forkhead box C2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9106663) Ensembl
MGI		 PMID:9106663 GO_REF:0000107 NCBI chr 5:71,951,980...71,955,021
Ensembl chr 5:71,952,632...71,954,134 		JBrowse link
G WNT3A Wnt family member 3A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9126297) MGI
Ensembl		 PMID:9126297 GO_REF:0000107 NCBI chr25:1,664,316...1,675,006
Ensembl chr25:1,666,053...1,719,881 		JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT3A Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:1,664,316...1,675,006
Ensembl chr25:1,666,053...1,719,881 		JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16943278) Ensembl
MGI		 PMID:16943278 GO_REF:0000107 NCBI chr 9:44,944,463...45,108,832
Ensembl chr 9:44,941,460...45,027,275 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16943278) Ensembl
MGI		 PMID:16943278 GO_REF:0000107 NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17042
    cellular process 16561
      cellular developmental process 4562
        cell differentiation 4561
          mesodermal cell differentiation 33
            mesodermal cell fate commitment 18
              axial mesodermal cell fate commitment + 1
              intermediate mesodermal cell fate commitment + 0
              lateral mesodermal cell fate commitment + 2
              mesodermal cell fate determination + 1
              mesodermal cell fate specification + 12
              paraxial mesodermal cell fate commitment + 2
Path 2
Term Annotations click to browse term
  biological_process 17042
    developmental process 6814
      anatomical structure development 6396
        multicellular organism development 5148
          embryo development 1339
            embryonic morphogenesis 699
              gastrulation 208
                formation of primary germ layer 138
                  mesoderm formation 80
                    mesodermal cell differentiation 33
                      mesodermal cell fate commitment 18
                        axial mesodermal cell fate commitment + 1
                        intermediate mesodermal cell fate commitment + 0
                        lateral mesodermal cell fate commitment + 2
                        mesodermal cell fate determination + 1
                        mesodermal cell fate specification + 12
                        paraxial mesodermal cell fate commitment + 2
paths to the root