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ONTOLOGY REPORT - ANNOTATIONS


Term:mesodermal cell fate commitment
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Accession:GO:0001710 term browser browse the term
Definition:The cell differentiation process that results in commitment of a cell to become part of the mesoderm.
Synonyms:exact_synonym: mesoderm cell fate commitment



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mesodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nanog Nanog homeobox acts_upstream_of_or_within ISO MGI:109452 (MGI:3654744|PMID:16801560) RGD PMID:16801560 MGI:3654744 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (MGI:1355046|PMID:10742100) RGD PMID:10742100 MGI:1355046 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Smad1 SMAD family member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1919200 (MGI:3654744|PMID:16801560)
Ensembl
RGD
PMID:16801560 GO_REF:0000107 MGI:3654744 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO (MGI:2677178|PMID:14511481) RGD PMID:14511481 MGI:2677178 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837
JBrowse link
BMP signaling pathway involved in mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etv2 ETS variant transcription factor 2 acts_upstream_of_or_within ISO (MGI:4415813|PMID:18462699) RGD PMID:18462699 MGI:4415813 NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431
JBrowse link
mesodermal cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857137 (MGI:76261|PMID:7657163)
Ensembl
RGD
PMID:7657163 GO_REF:0000107 MGI:76261 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
JBrowse link
G Hoxa11 homeobox A11 involved_in ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3768605|PMID:17785448)
UniProt
RGD
PMID:17785448 GO_REF:0000024 MGI:3768605 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Six2 SIX homeobox 2 involved_in ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:98956 (MGI:3711603|PMID:17462603) RGD PMID:17462603 MGI:3711603 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
paraxial mesodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO MGI:1857865 (MGI:86990|PMID:9106663) RGD PMID:9106663 MGI:86990 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737
JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO MGI:1857489 (MGI:86727|PMID:9126297) RGD PMID:9126297 MGI:86727 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO MGI:95522 (MGI:3702797|PMID:16943278) RGD PMID:16943278 MGI:3702797 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:1338938 (MGI:3702797|PMID:16943278) RGD PMID:16943278 MGI:3702797 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      cellular developmental process 4543
        cell differentiation 4448
          mesodermal cell differentiation 31
            mesodermal cell fate commitment 17
              axial mesodermal cell fate commitment + 1
              intermediate mesodermal cell fate commitment + 0
              lateral mesodermal cell fate commitment + 2
              mesodermal cell fate determination + 1
              mesodermal cell fate specification + 12
              paraxial mesodermal cell fate commitment + 2
Path 2
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        multicellular organism development 5727
          embryo development 1347
            embryonic morphogenesis 694
              gastrulation 207
                formation of primary germ layer 128
                  mesoderm formation 75
                    mesodermal cell differentiation 31
                      mesodermal cell fate commitment 17
                        axial mesodermal cell fate commitment + 1
                        intermediate mesodermal cell fate commitment + 0
                        lateral mesodermal cell fate commitment + 2
                        mesodermal cell fate determination + 1
                        mesodermal cell fate specification + 12
                        paraxial mesodermal cell fate commitment + 2
paths to the root