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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:cell fate determination
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Accession:GO:0001709 term browser browse the term
Definition:The cellular developmental process involved in cell fate commitment that occurs after cell fate specification, in which a cell is irreversibly committed to a cellular developmental fate which is heritable on cell division.
Synonyms:xref: Wikipedia:Cell_fate_determination



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cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 TAS RGD PMID:15990869 RGD:1578388 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Barhl2 BarH-like homeobox 2 acts_upstream_of_or_within ISO (MGI:2654373|PMID:12657654) RGD PMID:12657654 MGI:2654373 NCBI chr14:3,340,465...3,345,362
Ensembl chr14:3,340,465...3,345,353
JBrowse link
G Chrdl1 chordin-like 1 IMP RGD PMID:14684875 RGD:1299653 NCBI chr  X:106,889,125...106,992,937
Ensembl chr  X:106,889,125...106,992,921
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 acts_upstream_of_or_within ISO MGI:3039046 (MGI:3623704|PMID:16574820) RGD PMID:16574820 MGI:3623704 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Dll1 delta like canonical Notch ligand 1 TAS RGD PMID:14743446 RGD:1304491 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Dll3 delta like canonical Notch ligand 3 TAS RGD PMID:14743446 RGD:1304491 NCBI chr 1:83,562,011...83,570,008
Ensembl chr 1:83,562,014...83,569,750
JBrowse link
G Ebf2 EBF transcription factor 2 acts_upstream_of_or_within ISO (MGI:5495569|PMID:23499423) RGD PMID:23499423 MGI:5495569 NCBI chr15:41,435,509...41,634,403
Ensembl chr15:41,435,509...41,634,403
JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO (MGI:2137782|PMID:10367888) RGD PMID:10367888 MGI:2137782 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:2673774|PMID:12923059) RGD PMID:12923059 MGI:2673774 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of
involved_in
ISO
IEA
MGI:2149672 (MGI:2136156|PMID:11425898)
GO_REF:0000107
RGD
Ensembl
PMID:11425898 GO_REF:0000107 MGI:2136156 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hoxa2 homeobox A2 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2385711 (MGI:3608156|PMID:16221728)
GO_REF:0000107
RGD
Ensembl
PMID:16221728 GO_REF:0000107 MGI:3608156 NCBI chr 4:81,262,668...81,266,970
Ensembl chr 4:81,262,768...81,265,044
JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in NAS PMID:9268641
PMID:9207788
UniProt PMID:9268641 PMID:9207788 RGD:8553717, RGD:8553672 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
JBrowse link
G Jag2 jagged canonical Notch ligand 2 involved_in NAS PMID:8948600 UniProt PMID:8948600 RGD:69864 NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818
JBrowse link
G Nkx6-3 NK6 homeobox 3 acts_upstream_of_or_within ISO MGI:3795186 (MGI:3795066|PMID:18347062) RGD PMID:18347062 MGI:3795066 NCBI chr16:68,868,404...68,873,617
Ensembl chr16:68,868,404...68,873,617
JBrowse link
G Notch2 notch receptor 2 IDA RGD PMID:1295745 RGD:69906 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Pax2 paired box 2 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1857673 (MGI:2662558|PMID:12756174)
UniProt
RGD
PMID:12756174 GO_REF:0000024 MGI:2662558 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1934347 (MGI:2662558|PMID:12756174)
Ensembl
RGD
PMID:12756174 GO_REF:0000107 MGI:2662558 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1095405 (MGI:5571965|PMID:24492243) RGD PMID:24492243 MGI:5571965 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Ptch2 patched 2 acts_upstream_of_or_within ISO MGI:105373 (MGI:5571965|PMID:24492243) RGD PMID:24492243 MGI:5571965 NCBI chr 5:130,571,956...130,592,506
Ensembl chr 5:130,572,312...130,592,405
JBrowse link
asymmetric protein localization involved in cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt7a Wnt family member 7A acts_upstream_of_or_within ISO (MGI:3849215|PMID:19497282) RGD PMID:19497282 MGI:3849215 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981
JBrowse link
auditory receptor cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 acts_upstream_of_or_within ISO (MGI:3611666|PMID:16407553) RGD PMID:16407553 MGI:3611666 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154
JBrowse link
cardiac cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Isl1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:19571884)
(MGI:4438134|PMID:19620969)
GO_REF:0000107
RGD
Ensembl
PMID:19571884 PMID:19620969 GO_REF:0000107 MGI:4438134 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
endodermal cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4442295|PMID:20308546)
Ensembl
RGD
PMID:20308546 GO_REF:0000107 MGI:4442295 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO (MGI:4442295|PMID:20308546) RGD PMID:20308546 MGI:4442295 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
ganglion mother cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ntf4 neurotrophin 4 acts_upstream_of_or_within
involved_in
ISO
ISS
MGI:1933845 (MGI:1354095|PMID:10681461) RGD PMID:10681461 PMID:10681461 MGI:1354095, RGD:8554690 NCBI chr 1:95,893,560...95,896,391
Ensembl chr 1:95,893,457...95,897,243
JBrowse link
glial cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3722716|PMID:17706960)
GO_REF:0000107
RGD
Ensembl
PMID:17706960 GO_REF:0000107 MGI:3722716 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ntf3 neurotrophin 3 acts_upstream_of_or_within ISO MGI:1933844 (MGI:1335255|PMID:10384880) RGD PMID:10384880 MGI:1335255 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO MGI:2176173|MGI:3605892 (MGI:3611670|PMID:16330018) RGD PMID:16330018 MGI:3611670 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
mesodermal cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1857137 (MGI:76261|PMID:7657163)
GO_REF:0000107
RGD
Ensembl
PMID:7657163 GO_REF:0000107 MGI:76261 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
muscle cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO MGI:3718323 (MGI:3763703|PMID:17786239) RGD PMID:17786239 MGI:3763703 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Tbx2 T-box transcription factor 2 acts_upstream_of_or_within ISO MGI:3505715 (MGI:3487212|PMID:15459098) RGD PMID:15459098 MGI:3487212 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
JBrowse link
myoblast fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myod1 myogenic differentiation 1 involved_in
acts_upstream_of_or_within
ISS
ISO
PMID:12486129
(MGI:2651740|PMID:12486129)
RGD PMID:12486129 PMID:12486129 MGI:2651740, RGD:8554648 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
JBrowse link
negative regulation of cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2149672 (MGI:2136156|PMID:11425898)
Ensembl
RGD
PMID:11425898 GO_REF:0000107 MGI:2136156 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
neuroblast fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857470 (MGI:1926546|PMID:11032813), (MGI:2389286|PMID:12397111) RGD PMID:11032813 PMID:12397111 MGI:1926546 MGI:2389286 NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993
JBrowse link
neuron fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 acts_upstream_of_or_within ISO MGI:3619134 (MGI:3664674|PMID:16892058) RGD PMID:16892058 MGI:3664674 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2148567|MGI:2176173 (MGI:3529734|PMID:15708565)
GO_REF:0000107
RGD
Ensembl
PMID:15708565 GO_REF:0000107 MGI:3529734 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Fezf2 Fez family zinc finger 2 acts_upstream_of_or_within ISO (MGI:5604297|PMID:24997765) RGD PMID:24997765 MGI:5604297 NCBI chr15:12,768,614...12,777,554
Ensembl chr15:12,773,762...12,777,554
JBrowse link
G Foxg1 forkhead box G1 acts_upstream_of_or_within ISO (MGI:5440366|PMID:22726835) RGD PMID:22726835 MGI:5440366 NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607
JBrowse link
G Lbx1 ladybird homeobox 1 acts_upstream_of_or_within ISO MGI:1351209|MGI:2182635 (MGI:3607682|PMID:16234809) RGD PMID:16234809 MGI:3607682 NCBI chr 1:244,083,873...244,085,690
Ensembl chr 1:244,083,873...244,085,690
JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO MGI:2446434|MGI:2661065 (MGI:4360136|PMID:19592574) RGD PMID:19592574 MGI:4360136 NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416
JBrowse link
G Prox1 prospero homeobox 1 acts_upstream_of_or_within ISO MGI:2386336 (MGI:2658694|PMID:12692551) RGD PMID:12692551 MGI:2658694 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
JBrowse link
G Prrx1 paired related homeobox 1 acts_upstream_of_or_within ISO (MGI:5486509|PMID:23447615) RGD PMID:23447615 MGI:5486509 NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866
JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO MGI:3046939 (MGI:3611719|PMID:16339193) RGD PMID:16339193 MGI:3611719 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
ventral spinal cord interneuron fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (MGI:1334824|PMID:10217145) RGD PMID:10217145 MGI:1334824 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19527
    cellular process 18201
      cellular developmental process 4626
        cell fate determination 44
          asymmetric protein localization involved in cell fate determination + 1
          branched duct epithelial cell fate determination, open tracheal system 0
          cardiac cell fate determination + 4
          cell fate determination involved in pattern specification + 1
          compound eye cone cell fate determination 0
          ectodermal cell fate determination 0
          endodermal cell fate determination 2
          endothelial cell fate determination 0
          eosinophil fate determination 0
          epithelial cell fate determination, open tracheal system 0
          ganglion mother cell fate determination 1
          glial cell fate determination 3
          leading edge cell fate determination + 0
          mesodermal cell fate determination + 1
          muscle cell fate determination + 2
          myoblast fate determination + 1
          negative regulation of cell fate determination + 1
          neuroblast fate determination 1
          neuron fate determination + 11
          oocyte fate determination + 0
          pole cell fate determination 0
          positive regulation of cell fate determination + 0
          regulation of cell fate determination + 1
          stem cell fate determination + 0
          vulval cell fate determination 0
Path 2
Term Annotations click to browse term
  biological_process 19527
    cellular process 18201
      cellular developmental process 4626
        cell differentiation 4625
          cell fate commitment 284
            cell fate determination 44
              asymmetric protein localization involved in cell fate determination + 1
              branched duct epithelial cell fate determination, open tracheal system 0
              cardiac cell fate determination + 4
              cell fate determination involved in pattern specification + 1
              compound eye cone cell fate determination 0
              ectodermal cell fate determination 0
              endodermal cell fate determination 2
              endothelial cell fate determination 0
              eosinophil fate determination 0
              epithelial cell fate determination, open tracheal system 0
              ganglion mother cell fate determination 1
              glial cell fate determination 3
              leading edge cell fate determination + 0
              mesodermal cell fate determination + 1
              muscle cell fate determination + 2
              myoblast fate determination + 1
              negative regulation of cell fate determination + 1
              neuroblast fate determination 1
              neuron fate determination + 11
              oocyte fate determination + 0
              pole cell fate determination 0
              positive regulation of cell fate determination + 0
              regulation of cell fate determination + 1
              stem cell fate determination + 0
              vulval cell fate determination 0
paths to the root