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ONTOLOGY REPORT - ANNOTATIONS

Term:cell fate specification
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Accession:GO:0001708 term browser browse the term
Definition:The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate.

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cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936588:767,115...787,321
Ensembl chrNW_004936588:767,066...786,951 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16647304) Ensembl
MGI		 PMID:16647304 GO_REF:0000107 NCBI chrNW_004936572:6,176,267...6,268,885
Ensembl chrNW_004936572:6,176,255...6,272,260 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15866163) Ensembl
MGI		 PMID:15866163 GO_REF:0000107 NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293 		JBrowse link
G Dhh desert hedgehog signaling molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936512:6,885,607...6,889,955
Ensembl chrNW_004936512:6,885,607...6,889,992 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chrNW_004936596:2,728,089...2,735,718
Ensembl chrNW_004936596:2,728,114...2,735,317 		JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:18076286) MGI PMID:18076286 NCBI chrNW_004936620:2,966,341...2,969,349
Ensembl chrNW_004936620:2,966,341...2,969,349 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of ISO (PMID:16230531) MGI PMID:16230531 NCBI chrNW_004936537:6,610,565...6,618,509
Ensembl chrNW_004936537:6,610,565...6,618,450 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18582859) Ensembl
TreeGrafter
MGI		 PMID:18582859 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936569:1,474,693...1,480,562
Ensembl chrNW_004936569:1,474,665...1,480,568 		JBrowse link
G Mga MAX dimerization protein MGA involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936471:4,946,770...5,073,925
Ensembl chrNW_004936471:4,946,124...5,073,849 		JBrowse link
G Nkx2-3 NK2 homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:38311164) Ensembl
MGI		 PMID:38311164 GO_REF:0000107 NCBI chrNW_004936636:529,669...532,237
Ensembl chrNW_004936636:529,669...532,237 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (PMID:10367888) MGI PMID:10367888 NCBI chrNW_004936610:2,262,715...2,279,098
Ensembl chrNW_004936610:2,262,715...2,279,098 		JBrowse link
G Prdm14 PR/SET domain 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18622394) Ensembl
MGI		 PMID:18622394 GO_REF:0000107 NCBI chrNW_004936496:14,789,443...14,820,967
Ensembl chrNW_004936496:14,806,928...14,820,967 		JBrowse link
G Psen1 presenilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15525534) Ensembl
MGI		 PMID:15525534 GO_REF:0000107 NCBI chrNW_004936488:2,464,623...2,528,807
Ensembl chrNW_004936488:2,464,527...2,530,065 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (PMID:15525534) MGI PMID:15525534 NCBI chrNW_004936526:3,584,194...3,611,719
Ensembl chrNW_004936526:3,584,188...3,614,074 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12231626)
(PMID:16647304)
(PMID:18076286)		 Ensembl
TreeGrafter
MGI		 PMID:12231626 PMID:16647304 PMID:18076286 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936527:10,033,095...10,042,713
Ensembl chrNW_004936527:10,033,299...10,042,599 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chrNW_004936579:5,893,064...5,917,021
Ensembl chrNW_004936579:5,892,542...5,917,281 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:12514105) MGI PMID:12514105 NCBI chrNW_004936566:1,630,698...1,632,607
Ensembl chrNW_004936566:1,631,822...1,632,613 		JBrowse link
G Tbr1 T-box brain transcription factor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936469:17,481,049...17,489,535
Ensembl chrNW_004936469:17,479,842...17,490,710 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936619:3,662,567...3,670,470
Ensembl chrNW_004936619:3,664,468...3,670,525 		JBrowse link
G Tbx10 T-box transcription factor 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936599:2,152,281...2,158,332
Ensembl chrNW_004936599:2,152,272...2,158,332 		JBrowse link
G Tbx15 T-box transcription factor 15 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936627:3,745,399...3,852,861
Ensembl chrNW_004936627:3,745,287...3,853,309 		JBrowse link
G Tbx18 T-box transcription factor 18 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936510:6,366,450...6,396,056
Ensembl chrNW_004936510:6,366,846...6,393,882 		JBrowse link
G Tbx19 T-box transcription factor 19 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936481:17,990,435...18,013,180
Ensembl chrNW_004936481:17,990,435...18,013,193 		JBrowse link
G Tbx2 T-box transcription factor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936490:2,769,264...2,778,342
Ensembl chrNW_004936490:2,769,231...2,805,238 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936478:10,887,900...10,939,510
Ensembl chrNW_004936478:10,888,045...10,939,564 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936490:13,546,405...13,558,635
Ensembl chrNW_004936490:13,546,292...13,558,635 		JBrowse link
G Tbx22 T-box transcription factor 22 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936547:1,645,118...1,654,332
Ensembl chrNW_004936547:1,645,118...1,654,332 		JBrowse link
G Tbx3 T-box transcription factor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936558:7,230,361...7,243,651
Ensembl chrNW_004936558:7,230,668...7,244,361 		JBrowse link
G Tbx4 T-box transcription factor 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936490:2,823,531...2,853,282
Ensembl chrNW_004936490:2,827,416...2,852,917 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936558:7,408,229...7,454,897
Ensembl chrNW_004936558:7,408,222...7,454,901 		JBrowse link
G Tbx6 T-box transcription factor 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936501:12,402,709...12,407,571
Ensembl chrNW_004936501:12,402,724...12,407,571 		JBrowse link
G Tbxt T-box transcription factor T involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936489:16,027,359...16,035,041
Ensembl chrNW_004936489:16,027,359...16,035,041 		JBrowse link
G Tead4 TEA domain transcription factor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18083014) Ensembl
MGI		 PMID:18083014 GO_REF:0000107 NCBI chrNW_004936606:3,310,905...3,358,519
Ensembl chrNW_004936606:3,310,823...3,356,509 		JBrowse link
auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10364557) Ensembl
MGI		 PMID:10364557 GO_REF:0000107 NCBI chrNW_004936687:1,435,977...1,437,138
Ensembl chrNW_004936687:1,436,009...1,437,067 		JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14511481) Ensembl
MGI		 PMID:14511481 GO_REF:0000107 NCBI chrNW_004936521:8,171,146...8,178,802
Ensembl chrNW_004936521:8,171,146...8,178,705 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936477:3,354,336...3,445,248
Ensembl chrNW_004936477:3,349,627...3,461,797 		JBrowse link
cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9004034) Ensembl
MGI		 PMID:9004034 GO_REF:0000107 NCBI chrNW_004936574:1,465,981...1,495,717
Ensembl chrNW_004936574:1,465,897...1,495,762 		JBrowse link
G Tenm4 teneurin transmembrane protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17350578) Ensembl
MGI		 PMID:17350578 GO_REF:0000107 NCBI chrNW_004936498:7,145,510...7,868,792
Ensembl chrNW_004936498:7,145,483...7,658,860 		JBrowse link
endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21245162) Ensembl
TreeGrafter
MGI		 PMID:21245162 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936473:18,825,969...18,833,179
Ensembl chrNW_004936473:18,825,942...18,833,179 		JBrowse link
G Hnf1b HNF1 homeobox B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18635606) Ensembl
MGI		 PMID:18635606 GO_REF:0000107 NCBI chrNW_004936490:649,551...702,448
Ensembl chrNW_004936490:649,546...702,672 		JBrowse link
G Nanog Nanog homeobox acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518 NCBI chrNW_004936892:181,834...187,691 JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518 NCBI chrNW_004936837:827,568...838,933 JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936496:1,248,582...1,251,406
Ensembl chrNW_004936496:1,248,577...1,251,430 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21245162) MGI
Ensembl		 PMID:21245162 GO_REF:0000107 NCBI chrNW_004936566:1,630,698...1,632,607
Ensembl chrNW_004936566:1,631,822...1,632,613 		JBrowse link
endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa13 homeobox A13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18483557) Ensembl
MGI		 PMID:18483557 GO_REF:0000107 NCBI chrNW_004936478:3,824,715...3,827,277
Ensembl chrNW_004936478:3,824,715...3,827,277 		JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004937098:212,704...220,589
Ensembl chrNW_004937098:213,227...220,427 		JBrowse link
G Flvcr2 FLVCR choline and putative heme transporter 2 acts_upstream_of_or_within ISO (PMID:32369453) MGI PMID:32369453 NCBI chrNW_004936488:4,653,891...4,713,982
Ensembl chrNW_004936488:4,653,692...4,712,313 		JBrowse link
epidermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxi3 forkhead box I3 involved_in ISO (PMID:26450968) UniProt PMID:26450968 NCBI chrNW_004936712:517,566...522,709
Ensembl chrNW_004936712:517,562...522,925 		JBrowse link
G Notch1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15068794) Ensembl
MGI		 PMID:15068794 GO_REF:0000107 NCBI chrNW_004936669:1,292,016...1,334,061
Ensembl chrNW_004936669:1,292,088...1,332,428 		JBrowse link
G Ptch1 patched 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chrNW_004936626:4,241,993...4,301,919
Ensembl chrNW_004936626:4,241,908...4,309,476 		JBrowse link
G Ptch2 patched 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chrNW_004936474:26,052,277...26,069,500
Ensembl chrNW_004936474:26,052,305...26,069,312 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17079689) Ensembl
MGI		 PMID:17079689 GO_REF:0000107 NCBI chrNW_004936477:3,354,336...3,445,248
Ensembl chrNW_004936477:3,349,627...3,461,797 		JBrowse link
glial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfia nuclear factor I A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chrNW_004936522:612,357...1,171,079
Ensembl chrNW_004936522:615,012...957,282 		JBrowse link
G Nfib nuclear factor I B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chrNW_004936539:7,763,036...8,185,001
Ensembl chrNW_004936539:7,769,413...7,985,316 		JBrowse link
G Nfix nuclear factor I X acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chrNW_004936659:2,065,410...2,136,898
Ensembl chrNW_004936659:2,065,458...2,136,889 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12842915) Ensembl
MGI		 PMID:12842915 GO_REF:0000107 NCBI chrNW_004936655:1,849,044...1,852,648
Ensembl chrNW_004936655:1,847,272...1,852,705 		JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936648:395,526...546,705
Ensembl chrNW_004936648:395,524...546,729 		JBrowse link
G Hoxa11 homeobox A11 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936478:3,809,288...3,813,014
Ensembl chrNW_004936478:3,809,288...3,813,014 		JBrowse link
G Pax2 paired box 2 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chrNW_004936600:4,850,594...4,939,010
Ensembl chrNW_004936600:4,850,552...4,928,214 		JBrowse link
G Sfrp2 secreted frizzled related protein 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chrNW_004936576:604,174...612,440
Ensembl chrNW_004936576:604,069...613,021 		JBrowse link
G Six2 SIX homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936508:7,047,563...7,051,129
Ensembl chrNW_004936508:7,047,304...7,051,732 		JBrowse link
G Tbx6 T-box transcription factor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9490412) Ensembl
MGI		 PMID:9490412 GO_REF:0000107 NCBI chrNW_004936501:12,402,709...12,407,571
Ensembl chrNW_004936501:12,402,724...12,407,571 		JBrowse link
muscle cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myl2 myosin light chain 2 acts_upstream_of_or_within ISO (PMID:1379240) MGI PMID:1379240 NCBI chrNW_004936558:3,746,227...3,753,576
Ensembl chrNW_004936558:3,745,864...3,753,681 		JBrowse link
myoblast fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9004034) Ensembl
MGI		 PMID:9004034 GO_REF:0000107 NCBI chrNW_004936574:1,465,981...1,495,717
Ensembl chrNW_004936574:1,465,897...1,495,762 		JBrowse link
negative regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO (PMID:16230531) MGI PMID:16230531 NCBI chrNW_004936537:6,610,565...6,618,509
Ensembl chrNW_004936537:6,610,565...6,618,450 		JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd7 frizzled class receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936726:1,256,684...1,275,324
Ensembl chrNW_004936726:1,256,678...1,275,467 		JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:15,533,264...15,534,576
Ensembl chrNW_004936483:15,533,522...15,534,576 		JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936787:307,290...309,963
Ensembl chrNW_004936787:306,941...310,166 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:15,533,264...15,534,576
Ensembl chrNW_004936483:15,533,522...15,534,576 		JBrowse link
G Sfrp2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chrNW_004936576:604,174...612,440
Ensembl chrNW_004936576:604,069...613,021 		JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsc goosecoid homeobox involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936846:286,429...288,405
Ensembl chrNW_004936846:286,420...288,405 		JBrowse link
neuron fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16469766) Ensembl
MGI		 PMID:16469766 GO_REF:0000107 NCBI chrNW_004936492:11,315,929...11,317,166
Ensembl chrNW_004936492:11,316,417...11,317,166 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004937098:212,704...220,589
Ensembl chrNW_004937098:213,227...220,427 		JBrowse link
G Dmrta2 DMRT like family A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21576465) Ensembl
MGI		 PMID:21576465 GO_REF:0000107 NCBI chrNW_004936522:10,175,742...10,181,596
Ensembl chrNW_004936522:10,175,686...10,182,301 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24584053) Ensembl
MGI		 PMID:24584053 GO_REF:0000107 NCBI chrNW_004936727:1,648,451...1,663,294
Ensembl chrNW_004936727:1,648,448...1,663,455 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22513373) Ensembl
MGI		 PMID:22513373 GO_REF:0000107 NCBI chrNW_004936648:395,526...546,705
Ensembl chrNW_004936648:395,524...546,729 		JBrowse link
G Fev FEV transcription factor, ETS family member involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20818386) Ensembl
MGI		 PMID:20818386 GO_REF:0000107 NCBI chrNW_004936569:1,402,513...1,408,699
Ensembl chrNW_004936569:1,402,513...1,406,067 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15105374) Ensembl
MGI		 PMID:15105374 GO_REF:0000107 NCBI chrNW_004936596:2,728,089...2,735,718
Ensembl chrNW_004936596:2,728,114...2,735,317 		JBrowse link
G Foxa1 forkhead box A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17596284) Ensembl
MGI		 PMID:17596284 GO_REF:0000107 NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224 		JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:17922007)
(PMID:17596284)		 MGI PMID:17596284 PMID:17922007 NCBI chrNW_004936620:2,966,341...2,969,349
Ensembl chrNW_004936620:2,966,341...2,969,349 		JBrowse link
G Gsx2 GS homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15930101) Ensembl
MGI		 PMID:15930101 GO_REF:0000107 NCBI chrNW_004936482:16,703,936...16,706,224
Ensembl chrNW_004936482:16,704,193...16,705,729 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936480:15,805,259...15,817,854
Ensembl chrNW_004936480:15,805,247...15,817,854 		JBrowse link
G Isl2 ISL LIM homeobox 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936471:35,840,202...35,845,822
Ensembl chrNW_004936471:35,840,214...35,845,848 		JBrowse link
G Myt1l myelin transcription factor 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936532:557,680...916,082
Ensembl chrNW_004936532:560,327...688,232 		JBrowse link
G Nfia nuclear factor I A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chrNW_004936522:612,357...1,171,079
Ensembl chrNW_004936522:615,012...957,282 		JBrowse link
G Nfib nuclear factor I B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chrNW_004936539:7,763,036...8,185,001
Ensembl chrNW_004936539:7,769,413...7,985,316 		JBrowse link
G Nfix nuclear factor I X acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chrNW_004936659:2,065,410...2,136,898
Ensembl chrNW_004936659:2,065,458...2,136,889 		JBrowse link
G Nkx2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19592574)
(PMID:16339193)		 Ensembl
MGI		 PMID:16339193 PMID:19592574 GO_REF:0000107 NCBI chrNW_004936620:3,961,106...3,962,910
Ensembl chrNW_004936620:3,961,106...3,969,503 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ISO RGD PMID:15247919 RGD:2325628 NCBI chrNW_004936483:13,912,904...14,291,881
Ensembl chrNW_004936483:13,909,109...14,291,887 		JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO (PMID:15888661) MGI PMID:15888661 NCBI chrNW_004936495:1,433,124...1,449,409
Ensembl chrNW_004936495:1,432,598...1,442,918 		JBrowse link
G Pou3f2 POU class 3 homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936651:494,182...497,109
Ensembl chrNW_004936651:493,467...494,832 		JBrowse link
G Pou4f1 POU class 4 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936511:2,857,017...2,859,705
Ensembl chrNW_004936511:2,857,331...2,859,277 		JBrowse link
G Six1 SIX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22513373) Ensembl
MGI		 PMID:22513373 GO_REF:0000107 NCBI chrNW_004936495:4,839,496...4,842,906
Ensembl chrNW_004936495:4,838,051...4,842,994 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12842915) Ensembl
MGI		 PMID:12842915 GO_REF:0000107 NCBI chrNW_004936655:1,849,044...1,852,648
Ensembl chrNW_004936655:1,847,272...1,852,705 		JBrowse link
G Tbx1 T-box transcription factor 1 acts_upstream_of_or_within ISO (PMID:15084464)
(PMID:15064766)		 MGI PMID:15064766 PMID:15084464 NCBI chrNW_004936619:3,662,567...3,670,470
Ensembl chrNW_004936619:3,664,468...3,670,525 		JBrowse link
G Tlx3 T cell leukemia homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16234809)
(PMID:15064766)		 Ensembl
MGI		 PMID:15064766 PMID:16234809 GO_REF:0000107 NCBI chrNW_004936609:3,772,432...3,774,554
Ensembl chrNW_004936609:3,772,353...3,774,607 		JBrowse link
oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Olig2 oligodendrocyte transcription factor 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936500:9,244,595...9,247,756
Ensembl chrNW_004936500:9,245,880...9,247,756 		JBrowse link
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9828088) Ensembl
MGI		 PMID:9828088 GO_REF:0000107 NCBI chrNW_004936533:5,952,529...5,980,889
Ensembl chrNW_004936533:5,957,971...5,982,075 		JBrowse link
G Sox6 SRY-box transcription factor 6 acts_upstream_of_or_within ISO (PMID:17084361) MGI PMID:17084361 NCBI chrNW_004936528:2,331,706...2,912,423
Ensembl chrNW_004936528:2,331,661...2,906,082 		JBrowse link
positive regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afg2a AFG2 AAA ATPase homolog A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936662:1,957,364...2,207,410
Ensembl chrNW_004936662:1,886,176...1,929,097
Ensembl chrNW_004936662:1,886,176...1,929,097 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO (PMID:16230531) MGI PMID:16230531 NCBI chrNW_004936537:6,610,565...6,618,509
Ensembl chrNW_004936537:6,610,565...6,618,450 		JBrowse link
G Pax6 paired box 6 ISO RGD PMID:11880342 RGD:729590 NCBI chrNW_004936533:5,952,529...5,980,889
Ensembl chrNW_004936533:5,957,971...5,982,075 		JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936864:150,742...179,205
Ensembl chrNW_004936864:150,732...192,423 		JBrowse link
regulation of cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox17 SRY-box transcription factor 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936496:1,248,582...1,251,406
Ensembl chrNW_004936496:1,248,577...1,251,430 		JBrowse link
regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmo4 LIM domain only 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19323994) Ensembl
MGI		 PMID:19323994 GO_REF:0000107 NCBI chrNW_004936732:1,541,511...1,557,845
Ensembl chrNW_004936732:1,541,515...1,555,735 		JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936787:307,290...309,963
Ensembl chrNW_004936787:306,941...310,166 		JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esrp1 epithelial splicing regulatory protein 1 involved_in ISO (PMID:29107558) UniProt PMID:29107558 NCBI chrNW_004936544:7,633,266...7,690,624
Ensembl chrNW_004936544:7,633,071...7,691,655 		JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16943278) Ensembl
MGI		 PMID:16943278 GO_REF:0000107 NCBI chrNW_004936804:52,435...115,289
Ensembl chrNW_004936804:48,947...115,412 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16943278) Ensembl
MGI		 PMID:16943278 GO_REF:0000107 NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508 		JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A NOT|involved_in ISO (PMID:15073157) BHF-UCL PMID:15073157 NCBI chrNW_004936804:52,435...115,289
Ensembl chrNW_004936804:48,947...115,412 		JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chrNW_004936469:49,616,552...49,788,760
Ensembl chrNW_004936469:49,617,095...49,673,213 		JBrowse link
G Gli3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chrNW_004936478:17,129,922...17,403,630
Ensembl chrNW_004936478:17,126,911...17,403,011 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19684112) Ensembl
MGI		 PMID:19684112 GO_REF:0000107 NCBI chrNW_004936600:3,270,662...3,381,722
Ensembl chrNW_004936600:3,268,260...3,381,781 		JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chrNW_004936469:49,616,552...49,788,760
Ensembl chrNW_004936469:49,617,095...49,673,213 		JBrowse link
G Gli3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chrNW_004936478:17,129,922...17,403,630
Ensembl chrNW_004936478:17,126,911...17,403,011 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19684112) Ensembl
MGI		 PMID:19684112 GO_REF:0000107 NCBI chrNW_004936600:3,270,662...3,381,722
Ensembl chrNW_004936600:3,268,260...3,381,781 		JBrowse link
spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxc10 homeobox C10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18065432) Ensembl
MGI		 PMID:18065432 GO_REF:0000107 NCBI chrNW_004936512:11,207,173...11,212,365
Ensembl chrNW_004936512:11,207,173...11,212,365 		JBrowse link
G Hoxd10 homeobox D10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18065432) Ensembl
MGI		 PMID:18065432 GO_REF:0000107 NCBI chrNW_004936509:5,603,661...5,606,850
Ensembl chrNW_004936509:5,603,642...5,606,850 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chrNW_004936480:15,805,259...15,817,854
Ensembl chrNW_004936480:15,805,247...15,817,854 		JBrowse link
G Isl2 ISL LIM homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chrNW_004936471:35,840,202...35,845,822
Ensembl chrNW_004936471:35,840,214...35,845,848 		JBrowse link
G Lhx3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chrNW_004936669:1,561,433...1,573,074
Ensembl chrNW_004936669:1,564,102...1,573,047 		JBrowse link
G Lmo4 LIM domain only 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936732:1,541,511...1,557,845
Ensembl chrNW_004936732:1,541,515...1,555,735 		JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:10482234)
(PMID:18539116)		 MGI
UniProt		 PMID:10482234 PMID:18539116 NCBI chrNW_004936797:618,696...623,219 JBrowse link
G Olig3 oligodendrocyte transcription factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15769945) Ensembl
MGI		 PMID:15769945 GO_REF:0000107 NCBI chrNW_004936560:4,793,595...4,795,781
Ensembl chrNW_004936560:4,794,747...4,795,565 		JBrowse link
spinal cord oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chrNW_004936492:11,315,929...11,317,166
Ensembl chrNW_004936492:11,316,417...11,317,166 		JBrowse link
G Nkx2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chrNW_004936620:3,961,106...3,962,910
Ensembl chrNW_004936620:3,961,106...3,969,503 		JBrowse link
G Olig2 oligodendrocyte transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chrNW_004936500:9,244,595...9,247,756
Ensembl chrNW_004936500:9,245,880...9,247,756 		JBrowse link
stem cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmrta2 DMRT like family A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21576465) Ensembl
MGI		 PMID:21576465 GO_REF:0000107 NCBI chrNW_004936522:10,175,742...10,181,596
Ensembl chrNW_004936522:10,175,686...10,182,301 		JBrowse link
G Sfrp2 secreted frizzled related protein 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chrNW_004936576:604,174...612,440
Ensembl chrNW_004936576:604,069...613,021 		JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20228271) Ensembl
MGI		 PMID:20228271 GO_REF:0000107 NCBI chrNW_004936496:1,248,582...1,251,406
Ensembl chrNW_004936496:1,248,577...1,251,430 		JBrowse link
G Sox18 SRY-box transcription factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20228271) Ensembl
MGI		 PMID:20228271 GO_REF:0000107 NCBI chrNW_004936514:11,231,327...11,233,292
Ensembl chrNW_004936514:11,231,305...11,233,337 		JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11239429) Ensembl
MGI		 PMID:11239429 GO_REF:0000107 NCBI chrNW_004936654:1,139,500...1,143,477
Ensembl chrNW_004936654:1,139,500...1,143,477 		JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22932389) Ensembl
MGI		 PMID:22932389 GO_REF:0000107 NCBI chrNW_004936503:3,922,417...3,936,493
Ensembl chrNW_004936503:3,922,417...3,936,493 		JBrowse link
G Lhx3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chrNW_004936669:1,561,433...1,573,074
Ensembl chrNW_004936669:1,564,102...1,573,047 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chrNW_004936527:10,033,095...10,042,713
Ensembl chrNW_004936527:10,033,299...10,042,599 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16037
    cellular process 15650
      cellular developmental process 4329
        cell fate specification 102
          abaxial cell fate specification 0
          anther wall tapetum cell fate specification 0
          bundle sheath cell fate specification 0
          cardiac cell fate specification + 3
          cell fate specification involved in pattern specification + 7
          compound eye cone cell fate specification + 0
          ectodermal cell fate specification + 1
          endodermal cell fate specification + 8
          endothelial cell fate specification + 4
          eosinophil fate specification 0
          epidermal cell fate specification + 5
          epithelial cell type specification, open tracheal system + 0
          glial cell fate specification + 9
          mesodermal cell fate specification + 12
          muscle cell fate specification + 1
          myoblast fate specification + 1
          negative regulation of cell fate specification + 5
          neuroblast fate specification 0
          neuron fate specification + 40
          plant endodermal cell fate specification 0
          plant epidermal cell fate specification + 0
          positive regulation of cell fate specification + 4
          regulation of cell fate specification + 13
          skeletal muscle satellite cell fate specification 0
          stem cell fate specification + 6
          vulval cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 16037
    cellular process 15650
      cellular developmental process 4329
        cell differentiation 4328
          cell fate commitment 282
            cell fate specification 102
              abaxial cell fate specification 0
              anther wall tapetum cell fate specification 0
              bundle sheath cell fate specification 0
              cardiac cell fate specification + 3
              cell fate specification involved in pattern specification + 7
              compound eye cone cell fate specification + 0
              ectodermal cell fate specification + 1
              endodermal cell fate specification + 8
              endothelial cell fate specification + 4
              eosinophil fate specification 0
              epidermal cell fate specification + 5
              epithelial cell type specification, open tracheal system + 0
              glial cell fate specification + 9
              mesodermal cell fate specification + 12
              muscle cell fate specification + 1
              myoblast fate specification + 1
              negative regulation of cell fate specification + 5
              neuroblast fate specification 0
              neuron fate specification + 40
              plant endodermal cell fate specification 0
              plant epidermal cell fate specification + 0
              positive regulation of cell fate specification + 4
              regulation of cell fate specification + 13
              skeletal muscle satellite cell fate specification 0
              stem cell fate specification + 6
              vulval cell fate specification 0
paths to the root