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ONTOLOGY REPORT - ANNOTATIONS

Term:cell fate specification
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Accession:GO:0001708 term browser browse the term
Definition:The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate.


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cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDON cell adhesion associated, oncogene regulated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16647304) Ensembl
MGI		 PMID:16647304 GO_REF:0000107 NCBI chr 9:53,079,543...53,178,881
Ensembl chr 9:53,079,550...53,178,881 		JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15866163) Ensembl
MGI		 PMID:15866163 GO_REF:0000107 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311 		JBrowse link
G DHH desert hedgehog signaling molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:15,114,524...15,119,610
Ensembl chr 5:15,114,527...15,119,577 		JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chr 2:59,256,546...59,267,171
Ensembl chr 2:59,253,342...59,267,165 		JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:18076286) MGI PMID:18076286 NCBI chr17:29,997,397...30,001,704
Ensembl chr17:29,997,401...30,001,707 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor acts_upstream_of ISO (PMID:16230531) MGI PMID:16230531 NCBI chr 4:124,619,887...124,629,638
Ensembl chr 4:124,621,261...124,629,638 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:18582859) Ensembl
MGI
GO_Central		 PMID:18582859 GO_REF:0000033 GO_REF:0000107 NCBI chr15:121,083,750...121,090,548
Ensembl chr15:121,083,753...121,090,121 		JBrowse link
G MGA MAX dimerization protein MGA involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:129,590,645...129,697,434
Ensembl chr 1:129,594,795...129,697,408 		JBrowse link
G NKX2-3 NK2 homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:38311164) Ensembl
MGI		 PMID:38311164 GO_REF:0000107 NCBI chr14:110,720,384...110,724,002
Ensembl chr14:110,720,394...110,723,995 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (PMID:10367888) MGI PMID:10367888 NCBI chr13:168,510,671...168,530,394
Ensembl chr13:168,510,774...168,529,345 		JBrowse link
G PRDM14 PR/SET domain 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18622394) Ensembl
MGI		 PMID:18622394 GO_REF:0000107 NCBI chr 4:65,273,988...65,295,362
Ensembl chr 4:65,271,315...65,295,178 		JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15525534) Ensembl
MGI		 PMID:15525534 GO_REF:0000107 NCBI chr 7:96,478,179...96,567,884
Ensembl chr 7:96,478,190...96,569,130 		JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (PMID:15525534) MGI PMID:15525534 NCBI chr10:14,532,556...14,561,862
Ensembl chr10:14,532,767...14,577,251 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:16647304)
(PMID:18076286)
(PMID:12231626)		 Ensembl
MGI
GO_Central		 PMID:12231626 PMID:16647304 PMID:18076286 GO_REF:0000033 GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,994...2,555,484 		JBrowse link
G SMO smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chr18:19,450,730...19,478,796
Ensembl chr18:19,450,743...19,478,898 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:12514105) MGI PMID:12514105 NCBI chr13:119,668,476...119,669,435
Ensembl chr13:119,668,476...119,669,435 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISS UniProt GO_REF:0000024 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315 		JBrowse link
G TBR1 T-box brain transcription factor 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:68,208,884...68,222,993
Ensembl chr15:68,213,562...68,222,990 		JBrowse link
G TBX1 T-box transcription factor 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:51,289,376...51,297,110
Ensembl chr14:51,289,321...51,296,725 		JBrowse link
G TBX10 T-box transcription factor 10 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:4,945,381...4,948,117
Ensembl chr 2:4,941,136...4,948,781 		JBrowse link
G TBX18 T-box transcription factor 18 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:53,836,939...53,867,460
Ensembl chr 1:53,838,189...53,867,254 		JBrowse link
G TBX19 T-box transcription factor 19 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:82,663,121...82,699,261
Ensembl chr 4:82,663,581...82,697,813 		JBrowse link
G TBX2 T-box transcription factor 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:36,878,662...36,887,513
Ensembl chr12:36,878,675...36,887,513 		JBrowse link
G TBX20 T-box transcription factor 20 involved_in IBA GO_Central GO_REF:0000033 NCBI chr18:38,635,603...38,681,690
Ensembl chr18:38,635,617...38,678,133 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:23,996,415...24,009,353
Ensembl chr12:23,996,415...24,009,355 		JBrowse link
G TBX22 T-box transcription factor 22 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:63,837,576...63,845,704
Ensembl chr  X:63,837,284...63,846,483 		JBrowse link
G TBX3 T-box transcription factor 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:37,582,704...37,596,767
Ensembl chr14:37,582,822...37,596,766 		JBrowse link
G TBX4 T-box transcription factor 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:36,803,355...36,830,321
Ensembl chr12:36,802,354...36,834,327 		JBrowse link
G TBX6 T-box transcription factor 6 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:18,271,983...18,277,864
Ensembl chr 3:18,271,983...18,277,580 		JBrowse link
G TBXT T-box transcription factor T involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:2,717,165...2,725,561
Ensembl chr 1:2,717,165...2,725,601 		JBrowse link
G TEAD4 TEA domain transcription factor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18083014) Ensembl
MGI		 PMID:18083014 GO_REF:0000107 NCBI chr 5:67,130,392...67,167,579
Ensembl chr 5:67,118,317...67,194,072 		JBrowse link
auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATOH1 atonal bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10364557) Ensembl
MGI		 PMID:10364557 GO_REF:0000107 NCBI chr 8:125,768,232...125,770,619
Ensembl chr 8:125,768,286...125,770,545 		JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NODAL nodal growth differentiation factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14511481) Ensembl
MGI		 PMID:14511481 GO_REF:0000107 NCBI chr14:73,350,358...73,357,064
Ensembl chr14:73,353,258...73,360,654 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:19,933,035...20,166,746
Ensembl chr 8:19,922,779...20,166,754 		JBrowse link
cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9004034) Ensembl
MGI		 PMID:9004034 GO_REF:0000107 NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,396...56,173,326 		JBrowse link
G TENM4 teneurin transmembrane protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17350578) Ensembl
MGI		 PMID:17350578 GO_REF:0000107 NCBI chr 9:13,040,615...13,826,957
Ensembl chr 9:13,045,196...13,820,420 		JBrowse link
endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:21245162) GO_Central
MGI		 PMID:21245162 GO_REF:0000033 NCBI chr13:14,209,590...14,216,184
Ensembl chr13:14,209,736...14,215,797 		JBrowse link
G HNF1B HNF1 homeobox B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18635606) Ensembl
MGI		 PMID:18635606 GO_REF:0000107 NCBI chr12:39,143,119...39,201,631
Ensembl chr12:39,143,121...39,201,631 		JBrowse link
G NANOG Nanog homeobox acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518 NCBI chr 5:62,931,642...62,939,086
Ensembl chr 5:62,932,382...62,939,082 		JBrowse link
G POU5F1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518 NCBI chr 7:23,564,654...23,570,691 JBrowse link
G SOX17 SRY-box transcription factor 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:76,854,218...76,857,143
Ensembl chr 4:76,854,150...76,857,148 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21245162) MGI
Ensembl		 PMID:21245162 GO_REF:0000107 NCBI chr13:119,668,476...119,669,435
Ensembl chr13:119,668,476...119,669,435 		JBrowse link
endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOXA13 homeobox A13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18483557) Ensembl
MGI		 PMID:18483557 GO_REF:0000107 NCBI chr18:45,373,340...45,379,046
Ensembl chr18:45,373,440...45,376,325 		JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:198,815...211,346
Ensembl chr 1:199,358...211,346 		JBrowse link
G FLVCR2 FLVCR heme transporter 2 acts_upstream_of_or_within ISO (PMID:32369453) MGI PMID:32369453 NCBI chr 7:98,718,319...98,772,196
Ensembl chr 7:98,718,097...98,823,839 		JBrowse link
epidermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXI3 forkhead box I3 involved_in ISO (PMID:26450968) UniProt PMID:26450968 NCBI chr 3:57,586,669...57,590,366
Ensembl chr 3:57,586,485...57,590,344 		JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15068794) Ensembl
MGI		 PMID:15068794 GO_REF:0000107
G PTCH1 patched 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chr10:26,627,165...26,703,225
Ensembl chr10:26,627,425...26,703,223 		JBrowse link
G PTCH2 patched 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chr 6:166,491,649...166,513,137
Ensembl chr 6:166,495,763...166,512,648 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17079689) Ensembl
MGI		 PMID:17079689 GO_REF:0000107 NCBI chr 8:19,933,035...20,166,746
Ensembl chr 8:19,922,779...20,166,754 		JBrowse link
glial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFIA nuclear factor I A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chr 6:150,834,002...151,229,773
Ensembl chr 6:150,835,494...151,426,749 		JBrowse link
G NFIB nuclear factor I B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chr 1:208,182,397...208,427,504
Ensembl chr 1:208,175,194...208,421,602 		JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chr 2:65,954,808...66,056,591
Ensembl chr 2:65,954,811...66,056,567 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12842915) Ensembl
MGI		 PMID:12842915 GO_REF:0000107 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315 		JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EYA1 EYA transcriptional coactivator and phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:63,970,939...64,328,107
Ensembl chr 4:63,970,807...64,328,105 		JBrowse link
G HOXA11 homeobox A11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:45,388,523...45,392,190
Ensembl chr18:45,388,375...45,391,953 		JBrowse link
G PAX2 paired box 2 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chr14:111,822,334...111,914,950
Ensembl chr14:111,823,308...111,913,969 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chr 8:75,337,311...75,345,926
Ensembl chr 8:75,337,144...75,345,921 		JBrowse link
G SIX2 SIX homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:95,460,046...95,463,428
Ensembl chr 3:95,459,945...95,463,251 		JBrowse link
G TBX6 T-box transcription factor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9490412) Ensembl
MGI		 PMID:9490412 GO_REF:0000107 NCBI chr 3:18,271,983...18,277,864
Ensembl chr 3:18,271,983...18,277,580 		JBrowse link
muscle cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYL2 myosin light chain 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:1379240) GO_Central
MGI		 PMID:1379240 GO_REF:0000033 NCBI chr14:32,205,953...32,213,848
Ensembl chr14:32,205,273...32,213,722 		JBrowse link
myoblast fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9004034) Ensembl
MGI		 PMID:9004034 GO_REF:0000107 NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,396...56,173,326 		JBrowse link
negative regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GFI1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO (PMID:16230531) MGI PMID:16230531 NCBI chr 4:124,619,887...124,629,638
Ensembl chr 4:124,621,261...124,629,638 		JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FZD7 frizzled class receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:105,644,164...105,648,860
Ensembl chr15:105,644,188...105,648,850 		JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:55,322,016...55,327,600
Ensembl chr 7:55,322,274...55,323,539 		JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:97,487,854...97,490,118
Ensembl chr14:97,487,226...97,490,288 		JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:55,322,016...55,327,600
Ensembl chr 7:55,322,274...55,323,539 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chr 8:75,337,311...75,345,926
Ensembl chr 8:75,337,144...75,345,921 		JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSC goosecoid homeobox involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:116,099,053...116,101,153
Ensembl chr 7:116,098,327...116,101,338 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISS UniProt GO_REF:0000024 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315 		JBrowse link
neuron fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16469766) Ensembl
MGI		 PMID:16469766 GO_REF:0000107 NCBI chr 5:81,357,431...81,360,335
Ensembl chr 5:81,358,969...81,359,673 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:198,815...211,346
Ensembl chr 1:199,358...211,346 		JBrowse link
G DMRTA2 DMRT like family A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21576465) Ensembl
MGI		 PMID:21576465 GO_REF:0000107 NCBI chr 6:161,616,646...161,622,591
Ensembl chr 6:161,616,646...161,621,904 		JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24584053) Ensembl
MGI		 PMID:24584053 GO_REF:0000107 NCBI chr 7:23,977,683...23,992,673
Ensembl chr 7:23,977,683...23,992,697 		JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22513373) Ensembl
MGI		 PMID:22513373 GO_REF:0000107 NCBI chr 4:63,970,939...64,328,107
Ensembl chr 4:63,970,807...64,328,105 		JBrowse link
G FEV FEV transcription factor, ETS family member involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20818386) Ensembl
MGI		 PMID:20818386 GO_REF:0000107 NCBI chr15:121,005,279...121,008,748
Ensembl chr15:121,004,665...121,009,014 		JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15105374) Ensembl
MGI		 PMID:15105374 GO_REF:0000107 NCBI chr 2:59,256,546...59,267,171
Ensembl chr 2:59,253,342...59,267,165 		JBrowse link
G FOXA1 forkhead box A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17596284) Ensembl
MGI		 PMID:17596284 GO_REF:0000107 NCBI chr 7:62,471,233...62,479,638
Ensembl chr 7:62,471,249...62,479,220 		JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:17922007)
(PMID:17596284)		 MGI PMID:17596284 PMID:17922007 NCBI chr17:29,997,397...30,001,704
Ensembl chr17:29,997,401...30,001,707 		JBrowse link
G GSX2 GS homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15930101) Ensembl
MGI		 PMID:15930101 GO_REF:0000107 NCBI chr 8:40,880,093...40,883,928
Ensembl chr 8:40,881,552...40,883,995 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in IEA
IBA		 Ensembl
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr16:30,962,994...30,974,201
Ensembl chr16:30,963,000...30,973,907 		JBrowse link
G ISL2 ISL LIM homeobox 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:56,571,352...56,579,828
Ensembl chr 7:56,571,419...56,577,253 		JBrowse link
G MIR125A microRNA mir-125a involved_in ISO (PMID:22357933) BHF-UCL PMID:22357933 NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645 		JBrowse link
G MYT1L myelin transcription factor 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:131,928,059...132,294,015
Ensembl chr 3:132,125,508...132,294,013 		JBrowse link
G NFIA nuclear factor I A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chr 6:150,834,002...151,229,773
Ensembl chr 6:150,835,494...151,426,749 		JBrowse link
G NFIB nuclear factor I B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chr 1:208,182,397...208,427,504
Ensembl chr 1:208,175,194...208,421,602 		JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chr 2:65,954,808...66,056,591
Ensembl chr 2:65,954,811...66,056,567 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16339193)
(PMID:19592574)		 Ensembl
MGI		 PMID:16339193 PMID:19592574 GO_REF:0000107 NCBI chr17:29,275,656...29,279,572
Ensembl chr17:29,275,698...29,278,606 		JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 ISO RGD PMID:15247919 RGD:2325628 NCBI chr 1:191,535,262...191,941,675
Ensembl chr 1:191,535,301...191,925,327 		JBrowse link
G OTX2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO (PMID:15888661) MGI PMID:15888661 NCBI chr 1:186,028,575...186,039,026
Ensembl chr 1:186,028,579...186,038,229 		JBrowse link
G POU3F2 POU class 3 homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:65,835,375...65,842,872
Ensembl chr 1:65,835,995...65,837,323 		JBrowse link
G POU4F1 POU class 4 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:50,729,746...50,732,626
Ensembl chr11:50,730,428...50,732,539 		JBrowse link
G SIX1 SIX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22513373) Ensembl
MGI		 PMID:22513373 GO_REF:0000107 NCBI chr 1:189,620,430...189,624,652
Ensembl chr 1:189,619,855...189,624,651 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12842915) Ensembl
MGI		 PMID:12842915 GO_REF:0000107 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315 		JBrowse link
G TBX1 T-box transcription factor 1 acts_upstream_of_or_within ISO (PMID:15084464)
(PMID:15064766)		 MGI PMID:15064766 PMID:15084464 NCBI chr14:51,289,376...51,297,110
Ensembl chr14:51,289,321...51,296,725 		JBrowse link
G TLX3 T cell leukemia homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15064766)
(PMID:16234809)		 Ensembl
MGI		 PMID:15064766 PMID:16234809 GO_REF:0000107 NCBI chr16:52,823,839...52,826,717
Ensembl chr16:52,823,657...52,826,804 		JBrowse link
oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OLIG2 oligodendrocyte transcription factor 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr13:196,596,838...196,602,197
Ensembl chr13:196,599,822...196,600,793 		JBrowse link
G PAX6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9828088) Ensembl
MGI		 PMID:9828088 GO_REF:0000107 NCBI chr 2:28,971,565...29,001,149
Ensembl chr 2:28,978,287...29,001,200 		JBrowse link
G SOX6 SRY-box transcription factor 6 acts_upstream_of_or_within ISO (PMID:17084361) MGI PMID:17084361 NCBI chr 2:42,447,391...43,068,824
Ensembl chr 2:42,453,681...43,068,325 		JBrowse link
positive regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:18635606) MGI PMID:18635606 NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,885...101,343,916 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO (PMID:16230531) MGI PMID:16230531 NCBI chr 4:124,619,887...124,629,638
Ensembl chr 4:124,621,261...124,629,638 		JBrowse link
G PAX6 paired box 6 ISO RGD PMID:11880342 RGD:729590 NCBI chr 2:28,971,565...29,001,149
Ensembl chr 2:28,978,287...29,001,200 		JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT3A Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:51,153,978...51,203,678
Ensembl chr 2:51,153,970...51,202,176 		JBrowse link
regulation of cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOX17 SRY-box transcription factor 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:76,854,218...76,857,143
Ensembl chr 4:76,854,150...76,857,148 		JBrowse link
regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LMO4 LIM domain only 4 acts_upstream_of_or_within ISO (PMID:19323994) MGI PMID:19323994 NCBI chr 4:128,894,113...128,910,648 JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:97,487,854...97,490,118
Ensembl chr14:97,487,226...97,490,288 		JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESRP1 epithelial splicing regulatory protein 1 involved_in ISO (PMID:29107558) UniProt PMID:29107558 NCBI chr 4:41,993,944...42,061,706
Ensembl chr 4:41,993,948...42,061,236 		JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16943278) Ensembl
MGI		 PMID:16943278 GO_REF:0000107 NCBI chr14:87,743,270...87,891,790
Ensembl chr14:87,742,459...87,891,790 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16943278) Ensembl
MGI		 PMID:16943278 GO_REF:0000107 NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724 		JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A NOT|involved_in ISO (PMID:15073157) BHF-UCL PMID:15073157 NCBI chr14:87,743,270...87,891,790
Ensembl chr14:87,742,459...87,891,790 		JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr15:30,312,528...30,580,272
Ensembl chr15:30,313,817...30,579,306 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr18:52,403,463...52,697,906
Ensembl chr18:52,404,072...52,697,900 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19684112) Ensembl
MGI		 PMID:19684112 GO_REF:0000107 NCBI chr14:113,500,001...113,628,064
Ensembl chr14:113,500,842...113,626,003 		JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr15:30,312,528...30,580,272
Ensembl chr15:30,313,817...30,579,306 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr18:52,403,463...52,697,906
Ensembl chr18:52,404,072...52,697,900 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19684112) Ensembl
MGI		 PMID:19684112 GO_REF:0000107 NCBI chr14:113,500,001...113,628,064
Ensembl chr14:113,500,842...113,626,003 		JBrowse link
spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOXC10 homeobox C10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18065432) Ensembl
MGI		 PMID:18065432 GO_REF:0000107 NCBI chr 5:19,197,810...19,202,975
Ensembl chr 5:19,197,807...19,202,970 		JBrowse link
G HOXD10 homeobox D10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18065432) Ensembl
MGI		 PMID:18065432 GO_REF:0000107 NCBI chr15:81,911,372...81,921,164
Ensembl chr15:81,917,637...81,921,461 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chr16:30,962,994...30,974,201
Ensembl chr16:30,963,000...30,973,907 		JBrowse link
G ISL2 ISL LIM homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chr 7:56,571,352...56,579,828
Ensembl chr 7:56,571,419...56,577,253 		JBrowse link
G LHX3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107
G LMO4 LIM domain only 4 involved_in ISO (PMID:18539116) UniProt PMID:18539116 NCBI chr 4:128,894,113...128,910,648 JBrowse link
G MNX1 motor neuron and pancreas homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:10482234) InterPro
MGI
GO_Central		 PMID:10482234 GO_REF:0000002 GO_REF:0000033 NCBI chr18:1,724,930...1,730,724
Ensembl chr18:1,725,244...1,730,878 		JBrowse link
G OLIG3 oligodendrocyte transcription factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15769945) Ensembl
MGI		 PMID:15769945 GO_REF:0000107 NCBI chr 1:26,800,671...26,801,489
Ensembl chr 1:26,800,671...26,801,489 		JBrowse link
spinal cord oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chr 5:81,357,431...81,360,335
Ensembl chr 5:81,358,969...81,359,673 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chr17:29,275,656...29,279,572
Ensembl chr17:29,275,698...29,278,606 		JBrowse link
G OLIG2 oligodendrocyte transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chr13:196,596,838...196,602,197
Ensembl chr13:196,599,822...196,600,793 		JBrowse link
stem cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMRTA2 DMRT like family A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21576465) Ensembl
MGI		 PMID:21576465 GO_REF:0000107 NCBI chr 6:161,616,646...161,622,591
Ensembl chr 6:161,616,646...161,621,904 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chr 8:75,337,311...75,345,926
Ensembl chr 8:75,337,144...75,345,921 		JBrowse link
G SOX17 SRY-box transcription factor 17 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20228271) Ensembl
MGI		 PMID:20228271 GO_REF:0000107 NCBI chr 4:76,854,218...76,857,143
Ensembl chr 4:76,854,150...76,857,148 		JBrowse link
G SOX18 SRY-box transcription factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20228271) Ensembl
MGI		 PMID:20228271 GO_REF:0000107 NCBI chr17:62,869,868...62,871,758
Ensembl chr17:62,869,870...62,871,748 		JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBX1 developing brain homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11239429) Ensembl
MGI		 PMID:11239429 GO_REF:0000107 NCBI chr 2:39,229,392...39,234,304
Ensembl chr 2:39,229,356...39,234,969 		JBrowse link
G DMRT3 doublesex and mab-3 related transcription factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22932389) Ensembl
MGI		 PMID:22932389 GO_REF:0000107 NCBI chr 1:220,819,525...220,834,080
Ensembl chr 1:220,820,556...220,834,034 		JBrowse link
G LHX3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within ISO PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,994...2,555,484 		JBrowse link
G SOX1 SRY-box transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20844123) Ensembl
MGI		 PMID:20844123 GO_REF:0000107 NCBI chr11:77,985,771...77,989,383
Ensembl chr11:77,986,200...77,987,351 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17667
    cellular process 17205
      cellular developmental process 4499
        cell fate specification 100
          abaxial cell fate specification 0
          anther wall tapetum cell fate specification 0
          bundle sheath cell fate specification 0
          cardiac cell fate specification + 3
          cell fate specification involved in pattern specification + 8
          compound eye cone cell fate specification + 0
          ectodermal cell fate specification + 1
          endodermal cell fate specification + 8
          endothelial cell fate specification + 4
          eosinophil fate specification 0
          epidermal cell fate specification + 5
          epithelial cell type specification, open tracheal system + 0
          glial cell fate specification + 9
          mesodermal cell fate specification + 12
          muscle cell fate specification + 1
          myoblast fate specification + 1
          negative regulation of cell fate specification + 5
          neuroblast fate specification 0
          neuron fate specification + 42
          plant endodermal cell fate specification 0
          plant epidermal cell fate specification + 0
          positive regulation of cell fate specification + 4
          regulation of cell fate specification + 13
          skeletal muscle satellite cell fate specification 0
          stem cell fate specification + 7
          vulval cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 17667
    cellular process 17205
      cellular developmental process 4499
        cell differentiation 4498
          cell fate commitment 283
            cell fate specification 100
              abaxial cell fate specification 0
              anther wall tapetum cell fate specification 0
              bundle sheath cell fate specification 0
              cardiac cell fate specification + 3
              cell fate specification involved in pattern specification + 8
              compound eye cone cell fate specification + 0
              ectodermal cell fate specification + 1
              endodermal cell fate specification + 8
              endothelial cell fate specification + 4
              eosinophil fate specification 0
              epidermal cell fate specification + 5
              epithelial cell type specification, open tracheal system + 0
              glial cell fate specification + 9
              mesodermal cell fate specification + 12
              muscle cell fate specification + 1
              myoblast fate specification + 1
              negative regulation of cell fate specification + 5
              neuroblast fate specification 0
              neuron fate specification + 42
              plant endodermal cell fate specification 0
              plant epidermal cell fate specification + 0
              positive regulation of cell fate specification + 4
              regulation of cell fate specification + 13
              skeletal muscle satellite cell fate specification 0
              stem cell fate specification + 7
              vulval cell fate specification 0
paths to the root