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ONTOLOGY REPORT - ANNOTATIONS

Term:cell fate specification
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Accession:GO:0001708 term browser browse the term
Definition:The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate.

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cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624743:30,517,034...30,635,740
Ensembl chrNW_004624743:30,546,323...30,635,737 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624828:7,220,768...7,247,395
Ensembl chrNW_004624828:7,223,251...7,247,421 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated acts_upstream_of_or_within ISO (PMID:16647304) MGI PMID:16647304 NCBI chrNW_004624812:107,632...203,791
Ensembl chrNW_004624812:109,405...203,519 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15866163) Ensembl
MGI		 PMID:15866163 GO_REF:0000107 NCBI chrNW_004624730:77,876,361...77,887,228
Ensembl chrNW_004624730:77,875,257...77,887,234 		JBrowse link
G Dhh desert hedgehog signaling molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624816:3,096,137...3,100,882
Ensembl chrNW_004624816:3,095,849...3,104,228 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 acts_upstream_of_or_within ISO (PMID:18590716) MGI PMID:18590716 NCBI chrNW_004624908:1,713,590...1,720,709 JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:18076286) MGI PMID:18076286 NCBI chrNW_004624741:22,645,580...22,649,722
Ensembl chrNW_004624741:22,645,519...22,649,854 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of ISO (PMID:16230531) MGI PMID:16230531 NCBI chrNW_004624742:5,260,651...5,271,908
Ensembl chrNW_004624742:5,261,537...5,270,695 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18582859) Ensembl
TreeGrafter
MGI		 PMID:18582859 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624823:5,959,329...5,965,584
Ensembl chrNW_004624823:5,959,448...5,964,769 		JBrowse link
G Nkx2-3 NK2 homeobox 3 acts_upstream_of_or_within ISO (PMID:38311164) MGI PMID:38311164 NCBI chrNW_004624737:11,253,490...11,256,974
Ensembl chrNW_004624737:11,253,483...11,256,232 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (PMID:10367888) MGI PMID:10367888 NCBI chrNW_004624789:3,589,863...3,605,655
Ensembl chrNW_004624789:3,592,214...3,605,537 		JBrowse link
G Prdm14 PR/SET domain 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18622394) Ensembl
MGI		 PMID:18622394 GO_REF:0000107 NCBI chrNW_004624744:21,092,091...21,121,313
Ensembl chrNW_004624744:21,104,798...21,120,591 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO (PMID:15525534) MGI PMID:15525534 NCBI chrNW_004624734:28,200,358...28,272,684
Ensembl chrNW_004624734:28,200,140...28,272,743 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (PMID:15525534) MGI PMID:15525534 NCBI chrNW_004624771:17,183,538...17,205,460
Ensembl chrNW_004624771:17,183,447...17,224,188 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO (PMID:12231626)
(PMID:16647304)
(PMID:18076286)		 MGI PMID:12231626 PMID:16647304 PMID:18076286 NCBI chrNW_004624800:2,202,986...2,215,309
Ensembl chrNW_004624800:2,203,393...2,212,068 		JBrowse link
G Smo smoothened, frizzled class receptor acts_upstream_of_or_within ISO (PMID:18590716) MGI PMID:18590716 NCBI chrNW_004624783:7,012,385...7,039,302
Ensembl chrNW_004624783:7,011,899...7,039,921 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:12514105) MGI PMID:12514105 NCBI chrNW_004624730:59,570,879...59,573,001
Ensembl chrNW_004624730:59,570,915...59,571,871 		JBrowse link
G Tbx10 T-box transcription factor 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624767:18,918,933...18,923,369
Ensembl chrNW_004624767:18,919,516...18,924,547 		JBrowse link
G Tbx15 T-box transcription factor 15 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624772:14,483,951...14,611,602
Ensembl chrNW_004624772:14,482,948...14,611,452 		JBrowse link
G Tbx18 T-box transcription factor 18 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624799:9,694,167...9,721,468
Ensembl chrNW_004624799:9,694,374...9,719,385 		JBrowse link
G Tbx19 T-box transcription factor 19 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624826:6,243,809...6,268,973
Ensembl chrNW_004624826:6,243,809...6,267,989 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624740:25,645,526...25,698,235
Ensembl chrNW_004624740:25,645,895...25,697,132 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143 		JBrowse link
G Tbx22 T-box transcription factor 22 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624836:1,021,089...1,071,069 JBrowse link
G Tbx4 T-box transcription factor 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624871:2,365,836...2,390,269
Ensembl chrNW_004624871:2,366,823...2,390,269 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624747:18,307,294...18,348,040
Ensembl chrNW_004624747:18,307,294...18,348,040 		JBrowse link
G Tbx6 T-box transcription factor 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624782:13,169,096...13,174,498
Ensembl chrNW_004624782:13,169,719...13,174,056 		JBrowse link
G Tbxt T-box transcription factor T involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624785:13,058,520...13,066,607
Ensembl chrNW_004624785:13,058,444...13,066,719 		JBrowse link
G Tead4 TEA domain transcription factor 4 acts_upstream_of_or_within ISO (PMID:18083014) MGI PMID:18083014 NCBI chrNW_004624860:314,404...368,212
Ensembl chrNW_004624860:297,601...368,274 		JBrowse link
auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 acts_upstream_of_or_within ISO (PMID:10364557) MGI PMID:10364557 NCBI chrNW_004624757:21,517,650...21,519,543
Ensembl chrNW_004624757:21,517,809...21,518,864 		JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO (PMID:14511481) MGI PMID:14511481 NCBI chrNW_004624754:4,557,407...4,564,580
Ensembl chrNW_004624754:4,557,952...4,564,644 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:15466160) BHF-UCL PMID:15466160 NCBI chrNW_004624755:6,176,497...6,298,034
Ensembl chrNW_004624755:6,176,497...6,298,225 		JBrowse link
cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb1 integrin subunit beta 1 acts_upstream_of_or_within ISO (PMID:9004034) MGI PMID:9004034 NCBI chrNW_004624805:8,748,848...8,800,259
Ensembl chrNW_004624805:8,765,949...8,802,149 		JBrowse link
G Tenm4 teneurin transmembrane protein 4 acts_upstream_of_or_within ISO (PMID:17350578) MGI PMID:17350578 NCBI chrNW_004624863:1,643,173...2,374,330
Ensembl chrNW_004624863:1,643,076...2,149,630 		JBrowse link
endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21245162) MGI
TreeGrafter		 PMID:21245162 GO_REF:0000118 NCBI chrNW_004624788:5,550,569...5,557,342
Ensembl chrNW_004624788:5,550,445...5,557,321 		JBrowse link
G Hnf1b HNF1 homeobox B acts_upstream_of_or_within ISO (PMID:18635606) MGI PMID:18635606 NCBI chrNW_004624871:4,662,104...4,713,125
Ensembl chrNW_004624871:4,661,669...4,712,960 		JBrowse link
G Nanog Nanog homeobox acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518 NCBI chrNW_004624860:5,026,203...5,037,219 JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518 NCBI chrNW_004624754:24,758,055...24,764,723 JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO (PMID:21305474) BHF-UCL PMID:21305474 NCBI chrNW_004624735:1,276,382...1,278,584
Ensembl chrNW_004624735:1,276,302...1,279,181 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:21245162) MGI PMID:21245162 NCBI chrNW_004624730:59,570,879...59,573,001
Ensembl chrNW_004624730:59,570,915...59,571,871 		JBrowse link
endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa13 homeobox A13 acts_upstream_of_or_within ISO (PMID:18483557) MGI PMID:18483557 NCBI chrNW_004624739:3,405,860...3,410,426
Ensembl chrNW_004624739:3,406,436...3,410,851 		JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in ISO (PMID:22282195) UniProt PMID:22282195 NCBI chrNW_004624850:6,135,214...6,142,975
Ensembl chrNW_004624850:6,134,908...6,143,404 		JBrowse link
G Flvcr2 FLVCR choline and putative heme transporter 2 acts_upstream_of_or_within ISO (PMID:32369453) MGI PMID:32369453 NCBI chrNW_004624734:26,033,790...26,085,027
Ensembl chrNW_004624734:26,033,790...26,085,014 		JBrowse link
epidermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxi3 forkhead box I3 involved_in ISO (PMID:26450968) UniProt PMID:26450968 NCBI chrNW_004624749:16,033,754...16,041,679
Ensembl chrNW_004624749:16,033,767...16,039,249 		JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO (PMID:15068794) MGI PMID:15068794 NCBI chrNW_004624760:1,636,331...1,676,398
Ensembl chrNW_004624760:1,634,702...1,676,531 		JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO (PMID:24492243) MGI PMID:24492243 NCBI chrNW_004624753:16,929,503...16,995,255
Ensembl chrNW_004624753:16,935,251...16,995,389 		JBrowse link
G Ptch2 patched 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chrNW_004624906:707,270...726,570
Ensembl chrNW_004624906:706,492...726,519 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO (PMID:17079689) MGI PMID:17079689 NCBI chrNW_004624755:6,176,497...6,298,034
Ensembl chrNW_004624755:6,176,497...6,298,225 		JBrowse link
glial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfia nuclear factor I A acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chrNW_004624742:31,895,791...32,198,156
Ensembl chrNW_004624742:31,898,892...32,189,295 		JBrowse link
G Nfib nuclear factor I B acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chrNW_004624736:18,372,418...18,586,390
Ensembl chrNW_004624736:18,377,624...18,586,424 		JBrowse link
G Nfix nuclear factor I X acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chrNW_004624901:551,277...645,435
Ensembl chrNW_004624901:550,931...646,417 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:12842915) MGI PMID:12842915 NCBI chrNW_004624801:2,296,353...2,300,853
Ensembl chrNW_004624801:2,296,168...2,301,596 		JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chrNW_004624744:19,782,174...19,975,496
Ensembl chrNW_004624744:19,782,790...19,977,335 		JBrowse link
G Hoxa11 homeobox A11 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chrNW_004624739:3,420,501...3,424,151
Ensembl chrNW_004624739:3,418,723...3,423,950 		JBrowse link
G Pax2 paired box 2 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chrNW_004624831:375,851...453,968
Ensembl chrNW_004624831:375,866...453,930 		JBrowse link
G Sfrp2 secreted frizzled related protein 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chrNW_004624858:5,052,736...5,061,495
Ensembl chrNW_004624858:5,052,518...5,061,591 		JBrowse link
G Six2 SIX homeobox 2 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chrNW_004624738:26,442,935...26,447,100
Ensembl chrNW_004624738:26,442,965...26,446,942 		JBrowse link
G Tbx6 T-box transcription factor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9490412) Ensembl
MGI		 PMID:9490412 GO_REF:0000107 NCBI chrNW_004624782:13,169,096...13,174,498
Ensembl chrNW_004624782:13,169,719...13,174,056 		JBrowse link
muscle cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myl2 myosin light chain 2 acts_upstream_of_or_within ISO (PMID:1379240) MGI PMID:1379240 NCBI chrNW_004624747:21,108,998...21,113,993
Ensembl chrNW_004624747:21,109,061...21,113,993 		JBrowse link
myoblast fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb1 integrin subunit beta 1 acts_upstream_of_or_within ISO (PMID:9004034) MGI PMID:9004034 NCBI chrNW_004624805:8,748,848...8,800,259
Ensembl chrNW_004624805:8,765,949...8,802,149 		JBrowse link
negative regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO (PMID:16230531) MGI PMID:16230531 NCBI chrNW_004624742:5,260,651...5,271,908
Ensembl chrNW_004624742:5,261,537...5,270,695 		JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd7 frizzled class receptor 7 involved_in ISO (PMID:18681827) BHF-UCL PMID:18681827 NCBI chrNW_004624765:14,399,143...14,402,970 JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624791:11,313,139...11,316,998
Ensembl chrNW_004624791:11,313,142...11,315,982 		JBrowse link
G Sfrp2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chrNW_004624858:5,052,736...5,061,495
Ensembl chrNW_004624858:5,052,518...5,061,591 		JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsc goosecoid homeobox involved_in ISO (PMID:24290375) UniProt PMID:24290375 NCBI chrNW_004624734:7,367,030...7,369,081
Ensembl chrNW_004624734:7,367,277...7,368,817 		JBrowse link
neuron fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:16469766)
(PMID:24243019)		 MGI
UniProt		 PMID:16469766 PMID:24243019 NCBI chrNW_004624750:5,487,046...5,489,399
Ensembl chrNW_004624750:5,487,053...5,493,339 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISO (PMID:18997111) UniProt PMID:18997111 NCBI chrNW_004624850:6,135,214...6,142,975
Ensembl chrNW_004624850:6,134,908...6,143,404 		JBrowse link
G Dmrta2 DMRT like family A2 acts_upstream_of_or_within ISO (PMID:21576465) MGI PMID:21576465 NCBI chrNW_004624859:2,644,569...2,649,581
Ensembl chrNW_004624859:2,645,733...2,648,559 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 acts_upstream_of_or_within ISO (PMID:24584053) MGI PMID:24584053 NCBI chrNW_004624754:24,354,271...24,368,319
Ensembl chrNW_004624754:24,354,284...24,368,638 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of_or_within ISO (PMID:22513373) MGI PMID:22513373 NCBI chrNW_004624744:19,782,174...19,975,496
Ensembl chrNW_004624744:19,782,790...19,977,335 		JBrowse link
G Fev FEV transcription factor, ETS family member acts_upstream_of_or_within ISO (PMID:20818386) MGI PMID:20818386 NCBI chrNW_004624823:6,032,188...6,036,211
Ensembl chrNW_004624823:6,032,352...6,036,211 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 acts_upstream_of_or_within ISO (PMID:15105374) MGI PMID:15105374 NCBI chrNW_004624908:1,713,590...1,720,709 JBrowse link
G Foxa1 forkhead box A1 acts_upstream_of_or_within ISO (PMID:17596284) MGI PMID:17596284 NCBI chrNW_004624955:234,289...239,541
Ensembl chrNW_004624955:231,506...239,508 		JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:17922007)
(PMID:17596284)		 MGI PMID:17596284 PMID:17922007 NCBI chrNW_004624741:22,645,580...22,649,722
Ensembl chrNW_004624741:22,645,519...22,649,854 		JBrowse link
G Gsx2 GS homeobox 2 acts_upstream_of_or_within ISO (PMID:15930101) MGI PMID:15930101 NCBI chrNW_004624761:15,387,217...15,389,404
Ensembl chrNW_004624761:15,387,674...15,389,229 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624759:7,996,177...8,006,281
Ensembl chrNW_004624759:7,994,242...8,006,311 		JBrowse link
G Myt1l myelin transcription factor 1 like involved_in ISO (PMID:24243019), (PMID:28379941) UniProt PMID:24243019 PMID:28379941 NCBI chrNW_004624846:5,859,485...6,246,771
Ensembl chrNW_004624846:6,123,216...6,244,031 		JBrowse link
G Nfia nuclear factor I A acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chrNW_004624742:31,895,791...32,198,156
Ensembl chrNW_004624742:31,898,892...32,189,295 		JBrowse link
G Nfib nuclear factor I B acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chrNW_004624736:18,372,418...18,586,390
Ensembl chrNW_004624736:18,377,624...18,586,424 		JBrowse link
G Nfix nuclear factor I X acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chrNW_004624901:551,277...645,435
Ensembl chrNW_004624901:550,931...646,417 		JBrowse link
G Nkx2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19592574)
(PMID:16339193)		 Ensembl
MGI		 PMID:16339193 PMID:19592574 GO_REF:0000107 NCBI chrNW_004624741:21,857,911...21,860,128
Ensembl chrNW_004624741:21,852,205...21,860,040 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ISO RGD PMID:15247919 RGD:2325628 NCBI chrNW_004624768:15,239,111...15,619,979
Ensembl chrNW_004624768:15,252,354...15,619,601 		JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO (PMID:15888661) MGI PMID:15888661 NCBI chrNW_004624884:1,830,645...1,840,213 JBrowse link
G Pou3f2 POU class 3 homeobox 2 involved_in ISO (PMID:24243019) UniProt PMID:24243019 NCBI chrNW_004624810:6,283,443...6,287,594
Ensembl chrNW_004624810:6,286,066...6,287,397 		JBrowse link
G Pou4f1 POU class 4 homeobox 1 involved_in ISO (PMID:19877281), (PMID:20096094) BHF-UCL PMID:19877281 PMID:20096094 NCBI chrNW_004624751:21,812,567...21,817,837
Ensembl chrNW_004624751:21,812,850...21,814,747 		JBrowse link
G Six1 SIX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22513373) Ensembl
MGI		 PMID:22513373 GO_REF:0000107 NCBI chrNW_004624734:40,453,445...40,457,551
Ensembl chrNW_004624734:40,453,420...40,459,671 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624778:14,570,025...14,629,950
Ensembl chrNW_004624778:14,570,348...14,630,325 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:12842915) MGI PMID:12842915 NCBI chrNW_004624801:2,296,353...2,300,853
Ensembl chrNW_004624801:2,296,168...2,301,596 		JBrowse link
G Tbx1 T-box transcription factor 1 acts_upstream_of_or_within ISO (PMID:15084464)
(PMID:15064766)		 MGI PMID:15064766 PMID:15084464 NCBI chrNW_004624747:386,763...395,515
Ensembl chrNW_004624747:388,904...395,098 		JBrowse link
G Tlx3 T cell leukemia homeobox 3 acts_upstream_of_or_within ISO (PMID:16234809)
(PMID:15064766)		 MGI PMID:15064766 PMID:16234809 NCBI chrNW_004624733:18,760,060...18,762,909
Ensembl chrNW_004624733:18,759,941...18,762,854 		JBrowse link
oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9828088) Ensembl
MGI		 PMID:9828088 GO_REF:0000107 NCBI chrNW_004624766:20,536,581...20,554,589
Ensembl chrNW_004624766:20,536,233...20,554,759 		JBrowse link
G Sox6 SRY-box transcription factor 6 acts_upstream_of_or_within ISO (PMID:17084361) MGI PMID:17084361 NCBI chrNW_004624766:7,683,492...8,301,823
Ensembl chrNW_004624766:7,689,775...8,084,764 		JBrowse link
positive regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:18635606) MGI PMID:18635606 NCBI chrNW_004624777:3,268,674...3,321,424
Ensembl chrNW_004624777:3,268,953...3,321,145 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO (PMID:16230531) MGI PMID:16230531 NCBI chrNW_004624742:5,260,651...5,271,908
Ensembl chrNW_004624742:5,261,537...5,270,695 		JBrowse link
G Pax6 paired box 6 ISO RGD PMID:11880342 RGD:729590 NCBI chrNW_004624766:20,536,581...20,554,589
Ensembl chrNW_004624766:20,536,233...20,554,759 		JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:20559569) BHF-UCL PMID:20559569 NCBI chrNW_004624937:816,752...845,866
Ensembl chrNW_004624937:816,759...845,458 		JBrowse link
regulation of cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox17 SRY-box transcription factor 17 involved_in ISO (PMID:17360443) BHF-UCL PMID:17360443 NCBI chrNW_004624735:1,276,382...1,278,584
Ensembl chrNW_004624735:1,276,302...1,279,181 		JBrowse link
regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmo4 LIM domain only 4 acts_upstream_of_or_within ISO (PMID:19323994) MGI PMID:19323994 NCBI chrNW_004624742:10,207,901...10,224,807
Ensembl chrNW_004624742:10,207,899...10,225,209 		JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624791:11,313,139...11,316,998
Ensembl chrNW_004624791:11,313,142...11,315,982 		JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esrp1 epithelial splicing regulatory protein 1 involved_in ISO (PMID:29107558) UniProt PMID:29107558 NCBI chrNW_004624763:1,998,560...2,073,854
Ensembl chrNW_004624763:1,998,579...2,073,950 		JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO (PMID:16943278) MGI PMID:16943278 NCBI chrNW_004624841:218,642...304,744
Ensembl chrNW_004624841:219,133...265,397 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (PMID:16943278) MGI PMID:16943278 NCBI chrNW_004624780:5,161,245...5,212,641
Ensembl chrNW_004624780:5,161,073...5,213,870 		JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A NOT|involved_in ISO (PMID:15073157) BHF-UCL PMID:15073157 NCBI chrNW_004624841:218,642...304,744
Ensembl chrNW_004624841:219,133...265,397 		JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO (PMID:15215207) MGI PMID:15215207 NCBI chrNW_004624732:24,159,407...24,381,495
Ensembl chrNW_004624732:24,159,312...24,328,452 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO (PMID:15215207) MGI PMID:15215207 NCBI chrNW_004624740:18,961,395...19,238,760
Ensembl chrNW_004624740:18,975,596...19,235,900 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO (PMID:19684112) MGI PMID:19684112 NCBI chrNW_004624831:1,882,114...2,012,341
Ensembl chrNW_004624831:1,882,077...2,012,341 		JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO (PMID:15215207) MGI PMID:15215207 NCBI chrNW_004624732:24,159,407...24,381,495
Ensembl chrNW_004624732:24,159,312...24,328,452 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO (PMID:15215207) MGI PMID:15215207 NCBI chrNW_004624740:18,961,395...19,238,760
Ensembl chrNW_004624740:18,975,596...19,235,900 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO (PMID:19684112) MGI PMID:19684112 NCBI chrNW_004624831:1,882,114...2,012,341
Ensembl chrNW_004624831:1,882,077...2,012,341 		JBrowse link
spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxc10 homeobox C10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18065432) Ensembl
MGI		 PMID:18065432 GO_REF:0000107 NCBI chrNW_004624904:2,040,018...2,044,881
Ensembl chrNW_004624904:2,039,754...2,045,096 		JBrowse link
G Hoxd10 homeobox D10 acts_upstream_of_or_within ISO (PMID:18065432) MGI PMID:18065432 NCBI chrNW_004624787:13,256,600...13,260,664
Ensembl chrNW_004624787:13,257,387...13,262,685 		JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19666821) MGI
Ensembl		 PMID:19666821 GO_REF:0000107 NCBI chrNW_004624759:7,996,177...8,006,281
Ensembl chrNW_004624759:7,994,242...8,006,311 		JBrowse link
G Isl2 ISL LIM homeobox 2 acts_upstream_of_or_within ISO (PMID:19666821) MGI PMID:19666821 NCBI chrNW_004624894:1,852,337...1,855,827
Ensembl chrNW_004624894:1,852,114...1,855,761 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO (PMID:19666821) MGI PMID:19666821 NCBI chrNW_004624760:1,428,496...1,435,414
Ensembl chrNW_004624760:1,429,384...1,435,414 		JBrowse link
G Lmo4 LIM domain only 4 involved_in ISO (PMID:18539116) UniProt PMID:18539116 NCBI chrNW_004624742:10,207,901...10,224,807
Ensembl chrNW_004624742:10,207,899...10,225,209 		JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:10482234)
(PMID:18539116)		 MGI
UniProt		 PMID:10482234 PMID:18539116 NCBI chrNW_004624800:1,426,773...1,431,510
Ensembl chrNW_004624800:1,426,998...1,431,631 		JBrowse link
G Olig3 oligodendrocyte transcription factor 3 acts_upstream_of_or_within ISO (PMID:15769945) MGI PMID:15769945 NCBI chrNW_004624886:329,887...331,938
Ensembl chrNW_004624886:330,068...330,886 		JBrowse link
spinal cord oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within ISO (PMID:18287202) MGI PMID:18287202 NCBI chrNW_004624750:5,487,046...5,489,399
Ensembl chrNW_004624750:5,487,053...5,493,339 		JBrowse link
G Nkx2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chrNW_004624741:21,857,911...21,860,128
Ensembl chrNW_004624741:21,852,205...21,860,040 		JBrowse link
G Olig2 oligodendrocyte transcription factor 2 acts_upstream_of_or_within ISO (PMID:18287202) MGI PMID:18287202 NCBI chrNW_004624745:21,270,804...21,274,225
Ensembl chrNW_004624745:21,270,965...21,272,932 		JBrowse link
stem cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmrta2 DMRT like family A2 acts_upstream_of_or_within ISO (PMID:21576465) MGI PMID:21576465 NCBI chrNW_004624859:2,644,569...2,649,581
Ensembl chrNW_004624859:2,645,733...2,648,559 		JBrowse link
G Sfrp2 secreted frizzled related protein 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chrNW_004624858:5,052,736...5,061,495
Ensembl chrNW_004624858:5,052,518...5,061,591 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO (PMID:20228271) MGI PMID:20228271 NCBI chrNW_004624735:1,276,382...1,278,584
Ensembl chrNW_004624735:1,276,302...1,279,181 		JBrowse link
G Sox18 SRY-box transcription factor 18 acts_upstream_of_or_within ISO (PMID:20228271) MGI PMID:20228271 NCBI chrNW_004624741:29,679,274...29,681,069
Ensembl chrNW_004624741:29,679,091...29,681,049 		JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 acts_upstream_of_or_within ISO (PMID:11239429) MGI PMID:11239429 NCBI chrNW_004624766:11,431,699...11,444,150
Ensembl chrNW_004624766:11,440,470...11,444,150 		JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 acts_upstream_of_or_within ISO (PMID:22932389) MGI PMID:22932389 NCBI chrNW_004624736:5,648,318...5,662,301
Ensembl chrNW_004624736:5,648,318...5,661,584 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO (PMID:19666821) MGI PMID:19666821 NCBI chrNW_004624760:1,428,496...1,435,414
Ensembl chrNW_004624760:1,429,384...1,435,414 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chrNW_004624800:2,202,986...2,215,309
Ensembl chrNW_004624800:2,203,393...2,212,068 		JBrowse link
G Sox1 SRY-box transcription factor 1 acts_upstream_of_or_within ISO (PMID:20844123) MGI PMID:20844123 NCBI chrNW_004624793:1,341,643...1,648,168
Ensembl chrNW_004624793:1,370,243...1,371,358 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15172
    cellular process 14790
      cellular developmental process 4181
        cell fate specification 98
          abaxial cell fate specification 0
          anther wall tapetum cell fate specification 0
          bundle sheath cell fate specification 0
          cardiac cell fate specification + 3
          cell fate specification involved in pattern specification + 8
          compound eye cone cell fate specification + 0
          ectodermal cell fate specification + 1
          endodermal cell fate specification + 7
          endothelial cell fate specification + 4
          eosinophil fate specification 0
          epidermal cell fate specification + 5
          epithelial cell type specification, open tracheal system + 0
          glial cell fate specification + 9
          mesodermal cell fate specification + 11
          muscle cell fate specification + 1
          myoblast fate specification + 1
          negative regulation of cell fate specification + 4
          neuroblast fate specification 0
          neuron fate specification + 41
          plant endodermal cell fate specification 0
          plant epidermal cell fate specification + 0
          positive regulation of cell fate specification + 4
          regulation of cell fate specification + 12
          skeletal muscle satellite cell fate specification 0
          stem cell fate specification + 6
          vulval cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 15172
    cellular process 14790
      cellular developmental process 4181
        cell differentiation 4180
          cell fate commitment 273
            cell fate specification 98
              abaxial cell fate specification 0
              anther wall tapetum cell fate specification 0
              bundle sheath cell fate specification 0
              cardiac cell fate specification + 3
              cell fate specification involved in pattern specification + 8
              compound eye cone cell fate specification + 0
              ectodermal cell fate specification + 1
              endodermal cell fate specification + 7
              endothelial cell fate specification + 4
              eosinophil fate specification 0
              epidermal cell fate specification + 5
              epithelial cell type specification, open tracheal system + 0
              glial cell fate specification + 9
              mesodermal cell fate specification + 11
              muscle cell fate specification + 1
              myoblast fate specification + 1
              negative regulation of cell fate specification + 4
              neuroblast fate specification 0
              neuron fate specification + 41
              plant endodermal cell fate specification 0
              plant epidermal cell fate specification + 0
              positive regulation of cell fate specification + 4
              regulation of cell fate specification + 12
              skeletal muscle satellite cell fate specification 0
              stem cell fate specification + 6
              vulval cell fate specification 0
paths to the root