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ONTOLOGY REPORT - ANNOTATIONS

Term:cell fate specification
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Accession:GO:0001708 term browser browse the term
Definition:The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate.


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cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:252,052...380,506
Ensembl chr 3:253,081...322,993 		JBrowse link
G APC2 APC regulator of WNT signaling pathway 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:57,380,472...57,395,249
Ensembl chr20:57,380,460...57,395,226 		JBrowse link
G CDON cell adhesion associated, oncogene regulated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16647304) Ensembl
MGI		 PMID:16647304 GO_REF:0000107 NCBI chr 5:8,439,606...8,536,088
Ensembl chr 5:8,446,346...8,533,426 		JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15866163) Ensembl
MGI		 PMID:15866163 GO_REF:0000107 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927 		JBrowse link
G DHH desert hedgehog signaling molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr27:5,490,122...5,497,144
Ensembl chr27:5,490,441...5,494,636 		JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chr20:44,494,856...44,504,084
Ensembl chr20:44,489,219...44,598,497 		JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:18076286) MGI PMID:18076286 NCBI chr24:1,010,370...1,013,791
Ensembl chr24:1,010,651...1,013,072 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor acts_upstream_of ISO (PMID:16230531) MGI PMID:16230531 NCBI chr 6:56,473,032...56,484,422
Ensembl chr 6:56,256,305...56,484,422 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18582859) Ensembl
MGI
TreeGrafter		 PMID:18582859 GO_REF:0000107 GO_REF:0000118 NCBI chr37:25,616,942...25,622,989 JBrowse link
G MGA MAX dimerization protein MGA involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr30:8,633,122...8,805,822
Ensembl chr30:8,711,091...8,802,324 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (PMID:10367888) MGI PMID:10367888 NCBI chr31:769,454...788,761
Ensembl chr31:769,487...787,626 		JBrowse link
G PRDM14 PR/SET domain 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18622394) Ensembl
MGI		 PMID:18622394 GO_REF:0000107 NCBI chr29:19,203,798...19,220,149
Ensembl chr29:19,203,807...19,220,518 		JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15525534) Ensembl
MGI		 PMID:15525534 GO_REF:0000107 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532 		JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (PMID:15525534) MGI PMID:15525534 NCBI chr 7:38,147,157...38,163,023
Ensembl chr 7:38,147,173...38,166,722 		JBrowse link
G SFT2D2 SFT2 domain containing 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:30,258,748...30,281,371 JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16647304)
(PMID:12231626)
(PMID:18076286)		 Ensembl
MGI
TreeGrafter		 PMID:12231626 PMID:16647304 PMID:18076286 GO_REF:0000107 GO_REF:0000118 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903 		JBrowse link
G SMO smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chr14:7,518,871...7,527,703
Ensembl chr14:7,518,856...7,528,033 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:12514105) MGI PMID:12514105 NCBI chr34:14,853,000...14,855,153 JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172 		JBrowse link
G TBR1 T-box brain transcription factor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr36:6,989,644...6,997,916
Ensembl chr36:6,989,488...6,997,900 		JBrowse link
G TBX1 T-box transcription factor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr26:29,529,071...29,533,240
Ensembl chr26:29,528,878...29,532,784 		JBrowse link
G TBX10 T-box transcription factor 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:49,870,618...49,873,452
Ensembl chr18:49,866,920...49,873,190 		JBrowse link
G TBX10 T-box transcription factor 10 involved_in IEA TreeGrafter GO_REF:0000118
G TBX15 T-box transcription factor 15 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:56,079,739...56,190,417
Ensembl chr17:56,081,411...56,204,192 		JBrowse link
G TBX18 T-box transcription factor 18 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:44,901,076...44,929,730
Ensembl chr12:44,873,119...44,929,205 		JBrowse link
G TBX19 T-box transcription factor 19 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:30,198,912...30,248,410
Ensembl chr 7:30,185,850...30,365,512 		JBrowse link
G TBX2 T-box transcription factor 2 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:35,237,323...35,245,066
Ensembl chr 9:35,235,649...35,245,736 		JBrowse link
G TBX20 T-box transcription factor 20 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:46,891,706...46,946,899
Ensembl chr14:46,896,228...46,947,507 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261 		JBrowse link
G TBX3 T-box transcription factor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr26:11,694,885...11,709,594
Ensembl chr26:11,696,565...11,708,918 		JBrowse link
G TBX4 T-box transcription factor 4 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:35,163,346...35,197,726
Ensembl chr 9:35,166,353...35,191,932 		JBrowse link
G TBX5 T-box transcription factor 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr26:11,462,541...11,549,699
Ensembl chr26:11,463,653...11,506,446 		JBrowse link
G TBX6 T-box transcription factor 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:18,093,201...18,098,592
Ensembl chr 6:18,093,189...18,097,636 		JBrowse link
G TBXT T-box transcription factor T involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:54,183,495...54,192,331
Ensembl chr 1:54,183,153...54,192,352 		JBrowse link
G TEAD4 TEA domain transcription factor 4 acts_upstream_of_or_within ISO (PMID:18083014) MGI PMID:18083014 NCBI chr27:41,744,100...41,783,223
Ensembl chr27:41,748,871...41,803,556 		JBrowse link
G TIPRL TOR signaling pathway regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:30,291,330...30,329,317
Ensembl chr 7:30,185,850...30,365,512 		JBrowse link
activation of prostate induction by androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor acts_upstream_of_or_within ISO (PMID:17317769) MGI PMID:17317769 NCBI chr24:34,713,390...34,731,461
NCBI chr  X:51,969,785...52,167,450
Ensembl chr  X:51,969,785...52,151,912 		JBrowse link
auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATOH1 atonal bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10364557) Ensembl
MGI		 PMID:10364557 GO_REF:0000107 NCBI chr32:16,807,217...16,809,294
Ensembl chr32:16,807,336...16,808,406 		JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NODAL nodal growth differentiation factor acts_upstream_of_or_within ISO (PMID:14511481) MGI PMID:14511481 NCBI chr 4:21,366,828...21,374,623
Ensembl chr 4:21,367,583...21,375,151 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:84,060,417...84,286,008
Ensembl chr 3:84,064,440...84,286,360 		JBrowse link
cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9004034) Ensembl
MGI		 PMID:9004034 GO_REF:0000107 NCBI chr 2:3,728,472...3,757,696
Ensembl chr 2:3,670,596...3,756,961 		JBrowse link
G TENM4 teneurin transmembrane protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17350578) Ensembl
MGI		 PMID:17350578 GO_REF:0000107 NCBI chr21:17,819,846...20,234,096
Ensembl chr21:19,732,991...20,230,305 		JBrowse link
endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21245162) TreeGrafter
MGI		 PMID:21245162 GO_REF:0000118 NCBI chr23:16,476,498...16,512,406
Ensembl chr23:16,506,032...16,511,527 		JBrowse link
G HNF1B HNF1 homeobox B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18635606) Ensembl
MGI		 PMID:18635606 GO_REF:0000107 NCBI chr 9:37,437,992...37,493,200
Ensembl chr 9:37,438,583...37,492,993 		JBrowse link
G NANOG Nanog homeobox acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518 NCBI chr27:37,262,558...37,266,449 JBrowse link
G POU5F1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518
G SOX17 SRY-box transcription factor 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:5,979,092...5,981,504
Ensembl chr29:5,979,261...5,981,124 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:21245162) MGI PMID:21245162 NCBI chr34:14,853,000...14,855,153 JBrowse link
endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOXA13 homeobox A13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18483557) Ensembl
MGI		 PMID:18483557 GO_REF:0000107 NCBI chr14:40,371,234...40,375,261
Ensembl chr14:40,373,059...40,375,980 		JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 involved_in ISO (MGI:5466218|PMID:22282195) UniProt PMID:22282195 MGI:5466218 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348 		JBrowse link
G FLVCR2 FLVCR heme transporter 2 acts_upstream_of_or_within ISO (PMID:32369453) MGI PMID:32369453 NCBI chr 8:48,588,294...48,640,339
Ensembl chr 8:48,587,863...48,653,488 		JBrowse link
epidermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXI3 forkhead box I3 involved_in ISS UniProt GO_REF:0000024 NCBI chr17:38,032,479...38,036,424
Ensembl chr17:38,032,479...38,037,630 		JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15068794) Ensembl
MGI		 PMID:15068794 GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G PTCH1 patched 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chr 1:71,246,750...71,309,036
Ensembl chr 1:71,238,195...71,305,662 		JBrowse link
G PTCH2 patched 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chr15:15,488,357...15,503,748
Ensembl chr15:15,487,639...15,503,234 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17079689) Ensembl
MGI		 PMID:17079689 GO_REF:0000107 NCBI chr 3:84,060,417...84,286,008
Ensembl chr 3:84,064,440...84,286,360 		JBrowse link
glial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFIA nuclear factor I A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chr 5:48,489,521...49,064,867
Ensembl chr 5:48,496,773...49,064,848 		JBrowse link
G NFIB nuclear factor I B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chr11:34,573,136...35,010,319
Ensembl chr11:34,579,431...34,901,322 		JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chr20:49,117,087...49,187,023
Ensembl chr20:49,117,943...49,214,788 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12842915) Ensembl
MGI		 PMID:12842915 GO_REF:0000107 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172 		JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EYA1 EYA transcriptional coactivator and phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:20,176,306...20,595,131
Ensembl chr29:20,177,014...20,525,653 		JBrowse link
G HOXA11 homeobox A11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:40,355,907...40,360,120
Ensembl chr14:40,357,478...40,359,919 		JBrowse link
G PAX2 paired box 2 involved_in ISO (MGI:3768605|PMID:17785448) UniProt PMID:17785448 MGI:3768605 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of ISO (PMID:17462603) MGI PMID:17462603 NCBI chr15:51,541,197...51,548,765
Ensembl chr15:51,540,500...51,548,765 		JBrowse link
G SIX2 SIX homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:47,399,152...47,403,503
Ensembl chr10:47,400,034...47,403,509 		JBrowse link
G TBX6 T-box transcription factor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9490412) Ensembl
MGI		 PMID:9490412 GO_REF:0000107 NCBI chr 6:18,093,201...18,098,592
Ensembl chr 6:18,093,189...18,097,636 		JBrowse link
muscle cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYL2 myosin light chain 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1379240) TreeGrafter
MGI		 PMID:1379240 GO_REF:0000118 NCBI chr26:8,624,147...8,632,166
Ensembl chr26:8,464,176...8,632,232 		JBrowse link
myoblast fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9004034) Ensembl
MGI		 PMID:9004034 GO_REF:0000107 NCBI chr 2:3,728,472...3,757,696
Ensembl chr 2:3,670,596...3,756,961 		JBrowse link
negative regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GFI1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO (PMID:16230531) MGI PMID:16230531 NCBI chr 6:56,473,032...56,484,422
Ensembl chr 6:56,256,305...56,484,422 		JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FZD7 frizzled class receptor 7 involved_in ISO (PMID:18681827) BHF-UCL PMID:18681827 NCBI chr37:11,054,572...11,061,173
Ensembl chr37:11,053,521...11,060,821 		JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,738,333...52,739,962
Ensembl chr 3:52,738,366...52,739,755 		JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:35,697,428...35,701,596
Ensembl chr26:35,697,618...35,701,496 		JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,738,333...52,739,962
Ensembl chr 3:52,738,366...52,739,755 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within ISO (PMID:17462603) MGI PMID:17462603 NCBI chr15:51,541,197...51,548,765
Ensembl chr15:51,540,500...51,548,765 		JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSC goosecoid homeobox involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:63,684,149...63,707,030
Ensembl chr 8:63,684,137...63,707,054 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172 		JBrowse link
neuron fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16469766) Ensembl
MGI		 PMID:16469766 GO_REF:0000107 NCBI chr15:41,694,021...41,696,933
Ensembl chr15:41,694,269...41,695,391 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in ISO (MGI:3823133|PMID:18997111) UniProt PMID:18997111 MGI:3823133 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348 		JBrowse link
G DMRTA2 DMRT like family A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21576465) Ensembl
MGI		 PMID:21576465 GO_REF:0000107 NCBI chr15:10,706,096...10,710,506 JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24584053) Ensembl
MGI		 PMID:24584053 GO_REF:0000107 NCBI chr12:1,341,202...1,354,602
Ensembl chr12:1,341,191...1,354,584 		JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22513373) Ensembl
MGI		 PMID:22513373 GO_REF:0000107 NCBI chr29:20,176,306...20,595,131
Ensembl chr29:20,177,014...20,525,653 		JBrowse link
G FEV FEV transcription factor, ETS family member involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20818386) Ensembl
MGI		 PMID:20818386 GO_REF:0000107 NCBI chr37:25,548,578...25,552,092 JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15105374) Ensembl
MGI		 PMID:15105374 GO_REF:0000107 NCBI chr20:44,494,856...44,504,084
Ensembl chr20:44,489,219...44,598,497 		JBrowse link
G FOXA1 forkhead box A1 acts_upstream_of_or_within ISO (PMID:17596284) MGI PMID:17596284 NCBI chr 8:16,072,629...16,083,105
Ensembl chr 8:16,079,140...16,083,807 		JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:17596284)
(PMID:17922007)		 MGI PMID:17596284 PMID:17922007 NCBI chr24:1,010,370...1,013,791
Ensembl chr24:1,010,651...1,013,072 		JBrowse link
G GSX2 GS homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15930101) Ensembl
MGI		 PMID:15930101 GO_REF:0000107 NCBI chr13:46,640,172...46,642,405
Ensembl chr13:46,640,172...46,641,546 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:63,638,009...63,648,492
Ensembl chr 4:63,637,443...63,648,183 		JBrowse link
G ISL2 ISL LIM homeobox 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118
G MIR125A microRNA mir-125a involved_in ISO (PMID:22357933) BHF-UCL PMID:22357933 NCBI chr 1:105,400,273...105,400,332
Ensembl chr 1:105,400,270...105,400,337 		JBrowse link
G MYT1L myelin transcription factor 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:920,727...1,325,335
Ensembl chr17:922,276...1,057,585 		JBrowse link
G NFIA nuclear factor I A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chr 5:48,489,521...49,064,867
Ensembl chr 5:48,496,773...49,064,848 		JBrowse link
G NFIB nuclear factor I B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chr11:34,573,136...35,010,319
Ensembl chr11:34,579,431...34,901,322 		JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chr20:49,117,087...49,187,023
Ensembl chr20:49,117,943...49,214,788 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19592574)
(PMID:16339193)		 Ensembl
MGI		 PMID:16339193 PMID:19592574 GO_REF:0000107 NCBI chr24:1,933,176...1,935,875
Ensembl chr24:1,925,013...1,935,874 		JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 ISO RGD PMID:15247919 RGD:2325628 NCBI chr 3:51,131,470...51,491,112
Ensembl chr 3:51,138,751...51,513,024 		JBrowse link
G OTX2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO (PMID:15888661) MGI PMID:15888661 NCBI chr 8:32,435,169...32,445,093
Ensembl chr 8:32,435,863...32,445,446 		JBrowse link
G POU3F2 POU class 3 homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:57,103,712...57,108,522 JBrowse link
G POU4F1 POU class 4 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:31,992,657...31,997,066 JBrowse link
G SIX1 SIX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22513373) Ensembl
MGI		 PMID:22513373 GO_REF:0000107 NCBI chr 8:35,676,705...35,679,534
Ensembl chr 8:35,676,479...35,679,534 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12842915) Ensembl
MGI		 PMID:12842915 GO_REF:0000107 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172 		JBrowse link
G TBX1 T-box transcription factor 1 acts_upstream_of_or_within ISO (PMID:15064766)
(PMID:15084464)		 MGI PMID:15064766 PMID:15084464 NCBI chr26:29,529,071...29,533,240
Ensembl chr26:29,528,878...29,532,784 		JBrowse link
G TLX3 T cell leukemia homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15064766)
(PMID:16234809)		 Ensembl
MGI		 PMID:15064766 PMID:16234809 GO_REF:0000107 NCBI chr 4:40,816,351...40,818,582
Ensembl chr 4:40,816,467...40,818,723 		JBrowse link
oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OLIG2 oligodendrocyte transcription factor 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr31:27,674,112...27,677,521
Ensembl chr31:27,674,107...27,676,822 		JBrowse link
G PAX6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9828088) Ensembl
MGI		 PMID:9828088 GO_REF:0000107
G SOX6 SRY-box transcription factor 6 acts_upstream_of_or_within ISO (PMID:17084361) MGI PMID:17084361 NCBI chr21:38,737,072...39,320,257
Ensembl chr21:38,737,247...39,216,549 		JBrowse link
positive regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:18635606) MGI PMID:18635606 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO (PMID:16230531) MGI PMID:16230531 NCBI chr 6:56,473,032...56,484,422
Ensembl chr 6:56,256,305...56,484,422 		JBrowse link
G PAX6 paired box 6 ISO RGD PMID:11880342 RGD:729590
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT3A Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:864,393...899,698
Ensembl chr14:863,424...896,412 		JBrowse link
regulation of cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOX17 SRY-box transcription factor 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:5,979,092...5,981,504
Ensembl chr29:5,979,261...5,981,124 		JBrowse link
regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LMO4 LIM domain only 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19323994) Ensembl
MGI		 PMID:19323994 GO_REF:0000107 NCBI chr 6:60,892,478...60,909,910
Ensembl chr 6:60,727,270...60,941,058 		JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:35,697,428...35,701,596
Ensembl chr26:35,697,618...35,701,496 		JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESRP1 epithelial splicing regulatory protein 1 involved_in ISO (MGI:5915403|PMID:29107558) UniProt PMID:29107558 MGI:5915403 NCBI chr29:39,322,516...39,388,363
Ensembl chr29:39,333,117...39,387,337 		JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16943278) Ensembl
MGI		 PMID:16943278 GO_REF:0000107 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16943278) Ensembl
MGI		 PMID:16943278 GO_REF:0000107 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261 		JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A NOT|involved_in ISO (MGI:3040576|PMID:15073157) BHF-UCL PMID:15073157 MGI:3040576 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923 		JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr19:29,128,401...29,383,324
Ensembl chr19:29,130,227...29,383,658 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19684112) Ensembl
MGI		 PMID:19684112 GO_REF:0000107 NCBI chr28:14,992,989...15,115,499
Ensembl chr28:14,992,618...15,112,389 		JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr19:29,128,401...29,383,324
Ensembl chr19:29,130,227...29,383,658 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19684112) Ensembl
MGI		 PMID:19684112 GO_REF:0000107 NCBI chr28:14,992,989...15,115,499
Ensembl chr28:14,992,618...15,112,389 		JBrowse link
spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOXC10 homeobox C10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18065432) Ensembl
MGI		 PMID:18065432 GO_REF:0000107 NCBI chr27:1,272,272...1,277,411
Ensembl chr27:1,273,131...1,323,370 		JBrowse link
G HOXD10 homeobox D10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18065432) Ensembl
MGI		 PMID:18065432 GO_REF:0000107 NCBI chr36:19,924,352...19,927,706
Ensembl chr36:19,916,175...19,927,724 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chr 4:63,638,009...63,648,492
Ensembl chr 4:63,637,443...63,648,183 		JBrowse link
G ISL2 ISL LIM homeobox 2 acts_upstream_of_or_within ISO (PMID:19666821) MGI PMID:19666821
G LHX3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chr 9:49,248,555...49,254,128
Ensembl chr 9:49,248,621...49,254,118 		JBrowse link
G LMO4 LIM domain only 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:60,892,478...60,909,910
Ensembl chr 6:60,727,270...60,941,058 		JBrowse link
G MNX1 motor neuron and pancreas homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10482234) InterPro
TreeGrafter
MGI		 PMID:10482234 GO_REF:0000002 GO_REF:0000118 NCBI chr16:19,509,038...19,514,378
Ensembl chr16:19,499,582...19,512,836 		JBrowse link
G OLIG3 oligodendrocyte transcription factor 3 acts_upstream_of_or_within ISO (PMID:15769945) MGI PMID:15769945 NCBI chr 1:29,919,043...29,921,713
Ensembl chr 1:29,920,190...29,921,008 		JBrowse link
spinal cord oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chr15:41,694,021...41,696,933
Ensembl chr15:41,694,269...41,695,391 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chr24:1,933,176...1,935,875
Ensembl chr24:1,925,013...1,935,874 		JBrowse link
G OLIG2 oligodendrocyte transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chr31:27,674,112...27,677,521
Ensembl chr31:27,674,107...27,676,822 		JBrowse link
stem cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMRTA2 DMRT like family A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21576465) Ensembl
MGI		 PMID:21576465 GO_REF:0000107 NCBI chr15:10,706,096...10,710,506 JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of ISO (PMID:17462603) MGI PMID:17462603 NCBI chr15:51,541,197...51,548,765
Ensembl chr15:51,540,500...51,548,765 		JBrowse link
G SOX17 SRY-box transcription factor 17 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20228271) Ensembl
MGI		 PMID:20228271 GO_REF:0000107 NCBI chr29:5,979,092...5,981,504
Ensembl chr29:5,979,261...5,981,124 		JBrowse link
G SOX18 SRY-box transcription factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20228271) Ensembl
MGI		 PMID:20228271 GO_REF:0000107 NCBI chr24:47,494,581...47,496,563
Ensembl chr24:47,494,902...47,496,970 		JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBX1 developing brain homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11239429) Ensembl
MGI		 PMID:11239429 GO_REF:0000107 NCBI chr21:42,207,205...42,214,954
Ensembl chr21:42,208,346...42,212,415 		JBrowse link
G DMRT3 doublesex and mab-3 related transcription factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22932389) Ensembl
MGI		 PMID:22932389 GO_REF:0000107 NCBI chr 1:89,798,215...89,813,140
Ensembl chr 1:89,798,100...89,812,328 		JBrowse link
G LHX3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chr 9:49,248,555...49,254,128
Ensembl chr 9:49,248,621...49,254,118 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within ISO PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903 		JBrowse link
G SOX1 SRY-box transcription factor 1 acts_upstream_of_or_within ISO (PMID:20844123) MGI PMID:20844123 NCBI chr22:59,902,113...59,903,820 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    cellular process 16920
      cellular developmental process 4609
        cell fate specification 106
          abaxial cell fate specification 0
          anther wall tapetum cell fate specification 0
          bundle sheath cell fate specification 0
          cardiac cell fate specification + 3
          cell fate specification involved in pattern specification + 8
          compound eye cone cell fate specification + 0
          ectodermal cell fate specification + 1
          endodermal cell fate specification + 8
          endothelial cell fate specification + 4
          eosinophil fate specification 0
          epidermal cell fate specification + 5
          epithelial cell type specification, open tracheal system + 0
          glial cell fate specification + 9
          mesodermal cell fate specification + 12
          muscle cell fate specification + 1
          myoblast fate specification + 1
          negative regulation of cell fate specification + 5
          neuroblast fate specification 0
          neuron fate specification + 42
          plant endodermal cell fate specification 0
          plant epidermal cell fate specification + 0
          positive regulation of cell fate specification + 4
          regulation of cell fate specification + 14
          skeletal muscle satellite cell fate specification 0
          stem cell fate specification + 7
          vulval cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 17878
    cellular process 16920
      cellular developmental process 4609
        cell differentiation 4608
          cell fate commitment 287
            cell fate specification 106
              abaxial cell fate specification 0
              anther wall tapetum cell fate specification 0
              bundle sheath cell fate specification 0
              cardiac cell fate specification + 3
              cell fate specification involved in pattern specification + 8
              compound eye cone cell fate specification + 0
              ectodermal cell fate specification + 1
              endodermal cell fate specification + 8
              endothelial cell fate specification + 4
              eosinophil fate specification 0
              epidermal cell fate specification + 5
              epithelial cell type specification, open tracheal system + 0
              glial cell fate specification + 9
              mesodermal cell fate specification + 12
              muscle cell fate specification + 1
              myoblast fate specification + 1
              negative regulation of cell fate specification + 5
              neuroblast fate specification 0
              neuron fate specification + 42
              plant endodermal cell fate specification 0
              plant epidermal cell fate specification + 0
              positive regulation of cell fate specification + 4
              regulation of cell fate specification + 14
              skeletal muscle satellite cell fate specification 0
              stem cell fate specification + 7
              vulval cell fate specification 0
paths to the root