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ONTOLOGY REPORT - ANNOTATIONS

Term:cell fate specification
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Accession:GO:0001708 term browser browse the term
Definition:The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate.


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cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709 		JBrowse link
G CDON cell adhesion associated, oncogene regulated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16647304) Ensembl
MGI		 PMID:16647304 GO_REF:0000107 NCBI chr11:120,772,160...120,877,529
Ensembl chr11:124,685,084...124,786,091 		JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15866163) Ensembl
MGI		 PMID:15866163 GO_REF:0000107 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030 		JBrowse link
G DHH desert hedgehog signaling molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:39,656,046...39,661,439
Ensembl chr12:40,535,740...40,541,123 		JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chr19:18,009,505...18,021,772
Ensembl chr19:18,980,269...18,992,170 		JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:18076286) MGI PMID:18076286 NCBI chr20:22,519,942...22,524,262 JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor acts_upstream_of ISO (PMID:16230531) MGI PMID:16230531 NCBI chr 1:95,139,171...95,151,054
Ensembl chr 1:93,876,245...93,883,528 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18582859) Ensembl
TreeGrafter
MGI		 PMID:18582859 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506 		JBrowse link
G MGA MAX dimerization protein MGA involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:20,560,842...20,710,269
Ensembl chr15:38,839,708...38,948,847 		JBrowse link
G NKX2-3 NK2 homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:38311164) Ensembl
MGI		 PMID:38311164 GO_REF:0000107 NCBI chr10:96,146,636...96,150,238 JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (PMID:10367888) MGI PMID:10367888 NCBI chr 3:87,390,157...87,407,611
Ensembl chr 3:89,501,298...89,521,168 		JBrowse link
G PRDM14 PR/SET domain 14 acts_upstream_of_or_within ISO (PMID:18622394) MGI PMID:18622394 NCBI chr 8:66,578,674...66,599,360
Ensembl chr 8:68,240,741...68,260,263 		JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15525534) Ensembl
MGI		 PMID:15525534 GO_REF:0000107 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (PMID:15525534) MGI PMID:15525534 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18076286)
(PMID:16647304)
(PMID:12231626)		 Ensembl
TreeGrafter
MGI		 PMID:12231626 PMID:16647304 PMID:18076286 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G SMO smoothened, frizzled class receptor acts_upstream_of_or_within ISO (PMID:18590716) MGI PMID:18590716 NCBI chr 7:121,143,968...121,168,873
Ensembl chr 7:133,668,304...133,693,048 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:12514105) MGI PMID:12514105 NCBI chr 3:178,744,881...178,747,392
Ensembl chr 3:186,922,705...186,923,662 		JBrowse link
G TBX1 T-box transcription factor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:2,521,080...2,541,267 JBrowse link
G TBX10 T-box transcription factor 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:62,991,902...62,996,794
Ensembl chr11:66,303,253...66,311,529 		JBrowse link
G TBX15 T-box transcription factor 15 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:83,556,763...83,663,453
Ensembl chr 1:118,553,638...118,659,379 		JBrowse link
G TBX18 T-box transcription factor 18 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:82,621,987...82,654,137
Ensembl chr 6:85,862,810...85,938,799 		JBrowse link
G TBX19 T-box transcription factor 19 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr 1:147,492,846...147,524,740 JBrowse link
G TBX2 T-box transcription factor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:55,501,932...55,511,537
Ensembl chr17:60,622,098...60,630,189 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:9,791,008...9,803,894
Ensembl chr17:9,973,920...9,985,660 		JBrowse link
G TBX22 T-box transcription factor 22 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:69,070,218...69,087,243
Ensembl chr  X:79,177,534...79,198,782 		JBrowse link
G TBX3 T-box transcription factor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:112,240,050...112,254,299
Ensembl chr12:115,620,002...115,631,316 		JBrowse link
G TBX4 T-box transcription factor 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:55,554,549...55,587,253
Ensembl chr17:60,677,518...60,705,413 		JBrowse link
G TBX5 T-box transcription factor 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739 		JBrowse link
G TBX6 T-box transcription factor 6 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr16:30,460,305...30,467,070 JBrowse link
G TBXT T-box transcription factor T involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:164,112,117...164,122,253
Ensembl chr 6:169,095,723...169,106,595 		JBrowse link
G TEAD4 TEA domain transcription factor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18083014) Ensembl
MGI		 PMID:18083014 GO_REF:0000107 NCBI chr12:3,079,916...3,161,768
Ensembl chr12:3,011,544...3,092,022 		JBrowse link
auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATOH1 atonal bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10364557) Ensembl
MGI		 PMID:10364557 GO_REF:0000107 NCBI chr 4:86,188,534...86,191,301
Ensembl chr 4:96,863,762...96,864,832 		JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NODAL nodal growth differentiation factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14511481) Ensembl
MGI		 PMID:14511481 GO_REF:0000107 NCBI chr10:66,906,866...66,916,938
Ensembl chr10:69,433,959...69,443,972 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:15466160) BHF-UCL PMID:15466160 NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683 		JBrowse link
cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB1 integrin subunit beta 1 acts_upstream_of_or_within ISO (PMID:9004034) MGI PMID:9004034 NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031 		JBrowse link
G TENM4 teneurin transmembrane protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17350578) Ensembl
MGI		 PMID:17350578 GO_REF:0000107 NCBI chr11:73,712,808...75,001,831
Ensembl chr11:77,338,422...77,743,909 		JBrowse link
endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21245162) MGI
TreeGrafter		 PMID:21245162 GO_REF:0000118 NCBI chr 3:27,601,829...27,608,701
Ensembl chr 3:27,925,086...27,930,274 		JBrowse link
G HNF1B HNF1 homeobox B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18635606) Ensembl
MGI		 PMID:18635606 GO_REF:0000107 NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863 		JBrowse link
G NANOG Nanog homeobox acts_upstream_of_or_within ISO (PMID:20713518) MGI PMID:20713518 NCBI chr12:7,913,037...7,919,715 JBrowse link
G POU5F1 POU class 5 homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20713518) MGI
Ensembl		 PMID:20713518 GO_REF:0000107 NCBI chr 6:30,910,421...30,916,465
Ensembl chr 6:31,775,343...31,781,426 		JBrowse link
G SOX17 SRY-box transcription factor 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:50,883,088...50,885,542
Ensembl chr 8:48,257,287...48,259,808 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21245162) MGI
Ensembl		 PMID:21245162 GO_REF:0000107 NCBI chr 3:178,744,881...178,747,392
Ensembl chr 3:186,922,705...186,923,662 		JBrowse link
endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOXA13 homeobox A13 acts_upstream_of_or_within ISO (PMID:18483557) MGI PMID:18483557 NCBI chr 7:27,838,656...27,844,562 JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759 		JBrowse link
G FLVCR2 FLVCR choline and putative heme transporter 2 acts_upstream_of_or_within ISO (PMID:32369453) MGI PMID:32369453 NCBI chr14:56,132,370...56,209,882 JBrowse link
epidermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXI3 forkhead box I3 involved_in ISO (PMID:26450968) UniProt PMID:26450968 NCBI chr2A:87,578,732...87,585,111 JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15068794) Ensembl
MGI		 PMID:15068794 GO_REF:0000107 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G PTCH1 patched 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chr 9:66,542,675...66,616,820
Ensembl chr 9:94,668,365...94,741,453 		JBrowse link
G PTCH2 patched 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chr 1:44,125,693...44,147,462
Ensembl chr 1:45,490,789...45,513,055 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO (PMID:17079689) MGI PMID:17079689 NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683 		JBrowse link
glial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFIA nuclear factor I A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chr 1:60,331,945...60,713,729
Ensembl chr 1:61,938,945...62,526,753 		JBrowse link
G NFIB nuclear factor I B acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chr 9:13,923,516...14,376,264 JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chr19:12,557,020...12,660,316
Ensembl chr19:13,327,690...13,402,406 		JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:12842915) MGI PMID:12842915 NCBI chr17:66,028,737...66,034,122 JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EYA1 EYA transcriptional coactivator and phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:67,728,057...68,060,069
Ensembl chr 8:69,387,769...69,551,829 		JBrowse link
G HOXA11 homeobox A11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:27,826,003...27,829,757
Ensembl chr 7:27,424,759...27,429,103 		JBrowse link
G PAX2 paired box 2 involved_in ISO (PMID:17785448) UniProt PMID:17785448 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258 		JBrowse link
G SIX2 SIX homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:45,109,414...45,113,887
Ensembl chr2A:46,039,582...46,044,035 		JBrowse link
G TBX6 T-box transcription factor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9490412) Ensembl
MGI		 PMID:9490412 GO_REF:0000107 Ensembl chr16:30,460,305...30,467,070 JBrowse link
muscle cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYL2 myosin light chain 2 acts_upstream_of_or_within ISO (PMID:1379240) MGI PMID:1379240 NCBI chr12:108,479,941...108,489,739
Ensembl chr12:111,873,270...111,883,047 		JBrowse link
myoblast fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB1 integrin subunit beta 1 acts_upstream_of_or_within ISO (PMID:9004034) MGI PMID:9004034 NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031 		JBrowse link
negative regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GFI1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO (PMID:16230531) MGI PMID:16230531 NCBI chr 1:95,139,171...95,151,054
Ensembl chr 1:93,876,245...93,883,528 		JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FZD7 frizzled class receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:89,290,929...89,294,873
Ensembl chr2B:207,439,942...207,446,283 		JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:68,440,626...68,441,935
Ensembl chr15:87,645,768...87,647,210 		JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776 		JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:68,440,626...68,441,935
Ensembl chr15:87,645,768...87,647,210 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258 		JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSC goosecoid homeobox involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:75,390,119...75,392,050
Ensembl chr14:94,718,269...94,720,404 		JBrowse link
neuron fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16469766) Ensembl
MGI		 PMID:16469766 GO_REF:0000107 NCBI chr12:100,536,895...100,539,737
Ensembl chr12:103,932,302...103,932,999 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759 		JBrowse link
G DMRTA2 DMRT like family A2 acts_upstream_of_or_within ISO (PMID:21576465) MGI PMID:21576465 NCBI chr 1:49,659,379...49,665,262 JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24584053) Ensembl
MGI		 PMID:24584053 GO_REF:0000107 NCBI chr 6:31,542,946...31,560,894
Ensembl chr 6:32,429,271...32,451,844 		JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22513373) Ensembl
MGI		 PMID:22513373 GO_REF:0000107 NCBI chr 8:67,728,057...68,060,069
Ensembl chr 8:69,387,769...69,551,829 		JBrowse link
G FEV FEV transcription factor, ETS family member acts_upstream_of_or_within ISO (PMID:20818386) MGI PMID:20818386 NCBI chr2B:106,238,933...106,243,499 JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15105374) Ensembl
MGI		 PMID:15105374 GO_REF:0000107 NCBI chr19:18,009,505...18,021,772
Ensembl chr19:18,980,269...18,992,170 		JBrowse link
G FOXA1 forkhead box A1 acts_upstream_of_or_within ISO (PMID:17596284) MGI PMID:17596284 NCBI chr14:18,347,284...18,352,705 JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:17596284)
(PMID:17922007)		 MGI PMID:17596284 PMID:17922007 NCBI chr20:22,519,942...22,524,262 JBrowse link
G GSX2 GS homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15930101) Ensembl
MGI		 PMID:15930101 GO_REF:0000107 NCBI chr 4:69,837,643...69,840,101
Ensembl chr 4:76,397,180...76,399,715 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:62,635,095...62,650,141
Ensembl chr 5:64,252,715...64,264,674 		JBrowse link
G ISL2 ISL LIM homeobox 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr15:55,250,837...55,257,775
Ensembl chr15:74,843,797...74,848,635 		JBrowse link
G MYT1L myelin transcription factor 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:1,744,466...2,332,146
Ensembl chr2A:1,735,673...1,927,123 		JBrowse link
G NFIA nuclear factor I A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31128945) Ensembl
MGI		 PMID:31128945 GO_REF:0000107 NCBI chr 1:60,331,945...60,713,729
Ensembl chr 1:61,938,945...62,526,753 		JBrowse link
G NFIB nuclear factor I B acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chr 9:13,923,516...14,376,264 JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (PMID:31128945) MGI PMID:31128945 NCBI chr19:12,557,020...12,660,316
Ensembl chr19:13,327,690...13,402,406 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16339193)
(PMID:19592574)		 Ensembl
MGI		 PMID:16339193 PMID:19592574 GO_REF:0000107 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 ISO RGD PMID:15247919 RGD:2325628 NCBI chr15:66,566,219...66,953,279
Ensembl chr15:85,776,832...86,157,204 		JBrowse link
G OTX2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO (PMID:15888661) MGI PMID:15888661 NCBI chr14:37,370,926...37,381,610
Ensembl chr14:55,641,349...55,651,012 		JBrowse link
G POU3F2 POU class 3 homeobox 2 involved_in ISO (PMID:24243019) UniProt PMID:24243019 NCBI chr 6:96,677,651...96,682,145 JBrowse link
G POU4F1 POU class 4 homeobox 1 involved_in ISO (PMID:19877281), (PMID:20096094) BHF-UCL PMID:19877281 PMID:20096094 NCBI chr13:59,821,614...59,829,671 JBrowse link
G SIX1 SIX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22513373) Ensembl
MGI		 PMID:22513373 GO_REF:0000107 NCBI chr14:41,250,512...41,256,567
Ensembl chr14:59,515,324...59,527,494 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359 		JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:12842915) MGI PMID:12842915 NCBI chr17:66,028,737...66,034,122 JBrowse link
G TBX1 T-box transcription factor 1 acts_upstream_of_or_within ISO (PMID:15084464)
(PMID:15064766)		 MGI PMID:15064766 PMID:15084464 NCBI chr22:2,521,080...2,541,267 JBrowse link
G TLX3 T cell leukemia homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15064766)
(PMID:16234809)		 Ensembl
MGI		 PMID:15064766 PMID:16234809 GO_REF:0000107 NCBI chr 5:166,658,166...166,661,098
Ensembl chr 5:173,411,881...173,414,106 		JBrowse link
oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9828088) Ensembl
MGI		 PMID:9828088 GO_REF:0000107 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474 		JBrowse link
G SOX6 SRY-box transcription factor 6 acts_upstream_of_or_within ISO (PMID:17084361) MGI PMID:17084361 NCBI chr11:16,053,730...16,488,566
Ensembl chr11:15,747,495...16,175,246 		JBrowse link
positive regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:18635606) MGI PMID:18635606 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO (PMID:16230531) MGI PMID:16230531 NCBI chr 1:95,139,171...95,151,054
Ensembl chr 1:93,876,245...93,883,528 		JBrowse link
G PAX6 paired box 6 ISO RGD PMID:11880342 RGD:729590 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474 		JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT3A Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469 		JBrowse link
regulation of cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOX17 SRY-box transcription factor 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:50,883,088...50,885,542
Ensembl chr 8:48,257,287...48,259,808 		JBrowse link
regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LMO4 LIM domain only 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19323994) Ensembl
MGI		 PMID:19323994 GO_REF:0000107 NCBI chr 1:119,848,323...119,867,007
Ensembl chr 1:88,698,962...88,718,760 		JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776 		JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESRP1 epithelial splicing regulatory protein 1 involved_in ISO (PMID:29107558) UniProt PMID:29107558 NCBI chr 8:91,261,488...91,327,990
Ensembl chr 8:93,203,198...93,530,653 		JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16943278) Ensembl
MGI		 PMID:16943278 GO_REF:0000107 NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16943278) Ensembl
MGI		 PMID:16943278 GO_REF:0000107 NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904 		JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A NOT|involved_in ISO (PMID:15073157) BHF-UCL PMID:15073157 NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912 		JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr2B:7,665,403...7,922,840
Ensembl chr2B:121,303,831...121,497,442 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19684112) Ensembl
MGI		 PMID:19684112 GO_REF:0000107 NCBI chr10:99,107,516...99,231,761
Ensembl chr10:102,571,886...102,696,472 		JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr2B:7,665,403...7,922,840
Ensembl chr2B:121,303,831...121,497,442 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19684112) Ensembl
MGI		 PMID:19684112 GO_REF:0000107 NCBI chr10:99,107,516...99,231,761
Ensembl chr10:102,571,886...102,696,472 		JBrowse link
spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOXC10 homeobox C10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18065432) Ensembl
MGI		 PMID:18065432 GO_REF:0000107 NCBI chr12:34,764,956...34,770,088
Ensembl chr12:35,553,262...35,558,393 		JBrowse link
G HOXD10 homeobox D10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18065432) Ensembl
MGI		 PMID:18065432 GO_REF:0000107 NCBI chr2B:63,395,636...63,399,704
Ensembl chr2B:181,104,876...181,110,963 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chr 5:62,635,095...62,650,141
Ensembl chr 5:64,252,715...64,264,674 		JBrowse link
G ISL2 ISL LIM homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chr15:55,250,837...55,257,775
Ensembl chr15:74,843,797...74,848,635 		JBrowse link
G LHX3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chr 9:107,271,131...107,280,001
Ensembl chr 9:136,252,880...136,260,366 		JBrowse link
G LMO4 LIM domain only 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:119,848,323...119,867,007
Ensembl chr 1:88,698,962...88,718,760 		JBrowse link
G MNX1 motor neuron and pancreas homeobox 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:10482234)
(PMID:18539116)		 MGI
UniProt		 PMID:10482234 PMID:18539116 NCBI chr 7:148,622,701...148,628,532 JBrowse link
G OLIG3 oligodendrocyte transcription factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15769945) Ensembl
MGI		 PMID:15769945 GO_REF:0000107 NCBI chr 6:135,245,422...135,248,355
Ensembl chr 6:139,333,938...139,334,756 		JBrowse link
spinal cord oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chr12:100,536,895...100,539,737
Ensembl chr12:103,932,302...103,932,999 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18287202) Ensembl
MGI		 PMID:18287202 GO_REF:0000107 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
G OLIG2 oligodendrocyte transcription factor 2 acts_upstream_of_or_within ISO (PMID:18287202) MGI PMID:18287202 NCBI chr21:19,387,860...19,391,291 JBrowse link
stem cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMRTA2 DMRT like family A2 acts_upstream_of_or_within ISO (PMID:21576465) MGI PMID:21576465 NCBI chr 1:49,659,379...49,665,262 JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17462603) Ensembl
MGI		 PMID:17462603 GO_REF:0000107 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258 		JBrowse link
G SOX17 SRY-box transcription factor 17 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20228271) Ensembl
MGI		 PMID:20228271 GO_REF:0000107 NCBI chr 8:50,883,088...50,885,542
Ensembl chr 8:48,257,287...48,259,808 		JBrowse link
G SOX18 SRY-box transcription factor 18 acts_upstream_of_or_within ISO (PMID:20228271) MGI PMID:20228271
ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBX1 developing brain homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11239429) Ensembl
MGI		 PMID:11239429 GO_REF:0000107 NCBI chr11:20,180,704...20,185,164
Ensembl chr11:20,092,540...20,097,727 		JBrowse link
G DMRT3 doublesex and mab-3 related transcription factor 3 acts_upstream_of_or_within ISO (PMID:22932389) MGI PMID:22932389 NCBI chr 9:786,402...801,114 JBrowse link
G LHX3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19666821) Ensembl
MGI		 PMID:19666821 GO_REF:0000107 NCBI chr 9:107,271,131...107,280,001
Ensembl chr 9:136,252,880...136,260,366 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within ISO PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G SOX1 SRY-box transcription factor 1 acts_upstream_of_or_within ISO (PMID:20844123) MGI PMID:20844123 NCBI chr13:93,023,958...93,269,467 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16643
    cellular process 16206
      cellular developmental process 4464
        cell fate specification 100
          abaxial cell fate specification 0
          anther wall tapetum cell fate specification 0
          bundle sheath cell fate specification 0
          cardiac cell fate specification + 3
          cell fate specification involved in pattern specification + 8
          compound eye cone cell fate specification + 0
          ectodermal cell fate specification + 1
          endodermal cell fate specification + 8
          endothelial cell fate specification + 4
          eosinophil fate specification 0
          epidermal cell fate specification + 5
          epithelial cell type specification, open tracheal system + 0
          glial cell fate specification + 9
          mesodermal cell fate specification + 12
          muscle cell fate specification + 1
          myoblast fate specification + 1
          negative regulation of cell fate specification + 5
          neuroblast fate specification 0
          neuron fate specification + 41
          plant endodermal cell fate specification 0
          plant epidermal cell fate specification + 0
          positive regulation of cell fate specification + 4
          regulation of cell fate specification + 13
          skeletal muscle satellite cell fate specification 0
          stem cell fate specification + 6
          vulval cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 16643
    cellular process 16206
      cellular developmental process 4464
        cell differentiation 4463
          cell fate commitment 286
            cell fate specification 100
              abaxial cell fate specification 0
              anther wall tapetum cell fate specification 0
              bundle sheath cell fate specification 0
              cardiac cell fate specification + 3
              cell fate specification involved in pattern specification + 8
              compound eye cone cell fate specification + 0
              ectodermal cell fate specification + 1
              endodermal cell fate specification + 8
              endothelial cell fate specification + 4
              eosinophil fate specification 0
              epidermal cell fate specification + 5
              epithelial cell type specification, open tracheal system + 0
              glial cell fate specification + 9
              mesodermal cell fate specification + 12
              muscle cell fate specification + 1
              myoblast fate specification + 1
              negative regulation of cell fate specification + 5
              neuroblast fate specification 0
              neuron fate specification + 41
              plant endodermal cell fate specification 0
              plant epidermal cell fate specification + 0
              positive regulation of cell fate specification + 4
              regulation of cell fate specification + 13
              skeletal muscle satellite cell fate specification 0
              stem cell fate specification + 6
              vulval cell fate specification 0
paths to the root