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ONTOLOGY REPORT - ANNOTATIONS

Term:cell fate specification
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Accession:GO:0001708 term browser browse the term
Definition:The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.

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cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:12,258,468...12,280,459
Ensembl chr 7:12,258,468...12,275,609 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated IEA
ISO		 GO_REF:0000107
MGI:98297 (MGI:3624618|PMID:16647304)		 Ensembl
RGD		 PMID:16647304 GO_REF:0000107 MGI:3624618 NCBI chr 8:36,625,757...36,712,091
Ensembl chr 8:36,625,733...36,710,949 		JBrowse link
G Ctnnb1 catenin beta 1 IEA
ISO		 GO_REF:0000107
MGI:2148591|MGI:2148594|MGI:2450929 (MGI:3578464|PMID:15866163)		 Ensembl
RGD		 PMID:15866163 GO_REF:0000107 MGI:3578464 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Dhh desert hedgehog signaling molecule IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:140,575,288...140,580,783
Ensembl chr 7:140,575,288...140,580,783 		JBrowse link
G Eomes eomesodermin IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:127,144,367...127,152,618
Ensembl chr 8:127,144,903...127,151,493 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 ISO MGI:3042750 (MGI:3039989|PMID:15105374), (MGI:3806189|PMID:18590716) RGD PMID:15105374 PMID:18590716 MGI:3039989 MGI:3806189 NCBI chr16:20,645,956...20,652,890
Ensembl chr16:20,645,957...20,652,889 		JBrowse link
G Foxa2 forkhead box A2 ISS
ISO		 GO_REF:0000024
(MGI:3772421|PMID:18076286)		 ParkinsonsUK-UCL
RGD		 PMID:18076286 GO_REF:0000024 MGI:3772421 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481 		JBrowse link
G Ihh Indian hedgehog signaling molecule ISO
IBA		 MGI:1934258 (MGI:3807419|PMID:18582859)
PMID:21873635		 RGD PMID:18582859, PMID:21873635 MGI:3807419, RGD:13792537 NCBI chr 9:82,208,223...82,214,440
Ensembl chr 9:82,208,223...82,214,440 		JBrowse link
G Itgb1 integrin subunit beta 1 IEA
ISO		 GO_REF:0000107
MGI:2154539 (MGI:84974|PMID:9004034)		 Ensembl
RGD		 PMID:9004034 GO_REF:0000107 MGI:84974 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535 		JBrowse link
G Mga MAX dimerization protein MGA IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:111,669,645...111,760,822
Ensembl chr 3:111,699,021...111,759,911 		JBrowse link
G Notch1 notch receptor 1 ISO MGI:2178778 (MGI:3042356|PMID:15068794) RGD PMID:15068794 MGI:3042356 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
G Otx2 orthodenticle homeobox 2 ISO MGI:2176222|MGI:2661065 (MGI:3578035|PMID:15888661) RGD PMID:15888661 MGI:3578035 NCBI chr15:25,500,037...25,511,619
Ensembl chr15:25,502,019...25,505,691 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 ISO (MGI:2137782|PMID:10367888) RGD PMID:10367888 MGI:2137782 NCBI chr11:2,645,659...2,662,581
Ensembl chr11:2,645,865...2,662,579 		JBrowse link
G Prdm14 PR/SET domain 14 ISO MGI:3805889 (MGI:3805418|PMID:18622394) RGD PMID:18622394 MGI:3805418 NCBI chr 5:5,710,076...5,730,560
Ensembl chr 5:5,710,392...5,730,560 		JBrowse link
G Psen1 presenilin 1 ISO MGI:109284 (MGI:3513219|PMID:15525534) RGD PMID:15525534 MGI:3513219 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798 		JBrowse link
G Psen2 presenilin 2 ISO MGI:1202717 (MGI:3513219|PMID:15525534) RGD PMID:15525534 MGI:3513219 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724 		JBrowse link
G Shh sonic hedgehog signaling molecule IEA
IBA
ISO
ISS		 GO_REF:0000107
PMID:21873635
MGI:1857796|MGI:1926387 (MGI:2387225|PMID:12231626), (MGI:3624618|PMID:16647304), (MGI:3772421|PMID:18076286)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12231626 PMID:16647304 PMID:18076286, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:2387225 MGI:3624618 MGI:3772421, RGD:13792537 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691 		JBrowse link
G Smo smoothened, frizzled class receptor IEA
ISO		 GO_REF:0000107
MGI:2176255 (MGI:3806189|PMID:18590716)		 Ensembl
RGD		 PMID:18590716 GO_REF:0000107 MGI:3806189 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770 		JBrowse link
G Sox2 SRY-box transcription factor 2 ISO MGI:2449045 (MGI:2448211|PMID:12514105) RGD PMID:12514105 MGI:2448211 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545 		JBrowse link
G Sox9 SRY-box transcription factor 9 ISS
ISO		 GO_REF:0000024
MGI:2429649 (MGI:2667289|PMID:12842915)		 UniProt
RGD		 PMID:12842915 GO_REF:0000024 MGI:2667289 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379 		JBrowse link
G Tbr1 T-box brain transcription factor 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:47,677,720...47,685,902
Ensembl chr 3:47,677,720...47,685,902 		JBrowse link
G Tbx1 T-box transcription factor 1 ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
MGI:1351209|MGI:2179191 (MGI:3039048|PMID:15084464), (MGI:3044254|PMID:15064766)		 UniProt
RGD		 PMID:15064766 PMID:15084464, PMID:21873635 GO_REF:0000024 MGI:3039048 MGI:3044254, RGD:13792537 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969 		JBrowse link
G Tbx10 T-box transcription factor 10 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:219,237,204...219,246,480
Ensembl chr 1:219,243,447...219,246,262 		JBrowse link
G Tbx15 T-box transcription factor 15 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:201,289,042...201,390,752
Ensembl chr 2:201,289,357...201,390,745 		JBrowse link
G Tbx18 T-box transcription factor 18 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:95,359,354...95,387,363
Ensembl chr 8:95,359,354...95,387,363 		JBrowse link
G Tbx19 T-box transcription factor 19 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:83,403,263...83,426,305
Ensembl chr13:83,403,264...83,425,641 		JBrowse link
G Tbx2 T-box transcription factor 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921 		JBrowse link
G Tbx20 T-box transcription factor 20 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570 		JBrowse link
G Tbx21 T-box transcription factor 21 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331 		JBrowse link
G Tbx22 T-box transcription factor 22 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:78,731,738...78,782,542
Ensembl chr  X:78,769,419...78,782,542 		JBrowse link
G Tbx3 T-box transcription factor 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526 		JBrowse link
G Tbx4 T-box transcription factor 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:73,331,864...73,362,784
Ensembl chr10:73,333,119...73,362,783 		JBrowse link
G Tbx5 T-box transcription factor 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:42,059,688...42,148,226
Ensembl chr12:42,097,626...42,148,146 		JBrowse link
G Tbx6 T-box transcription factor 6 ISO
IBA		 MGI:2447721 (MGI:2447720|PMID:9490412)
PMID:21873635		 RGD PMID:9490412, PMID:21873635 MGI:2447720, RGD:13792537 NCBI chr 1:198,214,797...198,218,706
Ensembl chr 1:198,214,797...198,218,706 		JBrowse link
G Tbxt T-box transcription factor T IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:52,887,067...52,900,691
Ensembl chr 1:52,887,067...52,894,832 		JBrowse link
G Tead4 TEA domain transcription factor 4 ISO MGI:106907 (MGI:3770613|PMID:18083014) RGD PMID:18083014 MGI:3770613 NCBI chr 4:161,542,566...161,619,848
Ensembl chr 4:161,540,130...161,587,222 		JBrowse link
G Tlx3 T-cell leukemia, homeobox 3 ISO MGI:2180105|MGI:98769 (MGI:3044254|PMID:15064766) RGD PMID:15064766 MGI:3044254 NCBI chr10:18,128,869...18,131,745
Ensembl chr10:18,129,408...18,131,562 		JBrowse link
activation of prostate induction by androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor IEA
ISO		 GO_REF:0000107
MGI:3716756 (MGI:3714080|PMID:17317769)		 Ensembl
RGD		 PMID:17317769 GO_REF:0000107 MGI:3714080 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 ISO MGI:2155983 (MGI:1339217|PMID:10364557) RGD PMID:10364557 MGI:1339217 NCBI chr 4:95,498,003...95,500,098
Ensembl chr 4:95,498,003...95,500,089 		JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor ISO (MGI:2677178|PMID:14511481) RGD PMID:14511481 MGI:2677178 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO UniProtKB:P52800 (MGI:3056004|PMID:15466160) RGD PMID:15466160 MGI:3056004 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450 		JBrowse link
BMP signaling pathway involved in mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etv2 ETS variant transcription factor 2 ISO (MGI:4415813|PMID:18462699) RGD PMID:18462699 MGI:4415813 NCBI chr 1:89,091,239...89,094,570
Ensembl chr 1:89,091,239...89,094,530 		JBrowse link
cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tenm4 teneurin transmembrane protein 4 ISO MGI:3655239 (MGI:5429684|PMID:17350578) RGD PMID:17350578 MGI:5429684 NCBI chr 1:161,183,858...161,885,094
Ensembl chr 1:161,401,527...161,880,923 		JBrowse link
endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin ISO
IBA		 MGI:3774028 (MGI:4887279|PMID:21245162)
PMID:21873635		 RGD PMID:21245162, PMID:21873635 MGI:4887279, RGD:13792537 NCBI chr 8:127,144,367...127,152,618
Ensembl chr 8:127,144,903...127,151,493 		JBrowse link
G Hnf1b HNF1 homeobox B ISO MGI:1857856 (MGI:3807614|PMID:18635606) RGD PMID:18635606 MGI:3807614 NCBI chr10:71,159,863...71,218,902
Ensembl chr10:71,159,869...71,218,902 		JBrowse link
G Nanog Nanog homeobox ISO (PMID:20713518) RGD PMID:20713518 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 ISO (PMID:20713518) RGD PMID:20713518 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994 		JBrowse link
G Sox2 SRY-box transcription factor 2 ISO (PMID:21245162) RGD PMID:21245162 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545 		JBrowse link
endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa13 homeo box A13 ISO MGI:2152356 (MGI:3797428|PMID:18483557) RGD PMID:18483557 MGI:3797428 Ensembl chr 4:82,228,017...82,229,397 JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 IEA
ISO
ISS		 GO_REF:0000107
(MGI:5466218|PMID:22282195)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22282195 GO_REF:0000024 GO_REF:0000107 MGI:5466218 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379 		JBrowse link
epidermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptch1 patched 1 ISO MGI:1095405 (MGI:5571965|PMID:24492243) RGD PMID:24492243 MGI:5571965 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873 		JBrowse link
G Ptch2 patched 2 ISO MGI:105373 (MGI:5571965|PMID:24492243) RGD PMID:24492243 MGI:5571965 NCBI chr 5:135,962,252...135,983,816
Ensembl chr 5:135,962,911...135,983,816 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO MGI:1926500|MGI:3583755 (MGI:3689772|PMID:17079689) RGD PMID:17079689 MGI:3689772 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450 		JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eya1 EYA transcriptional coactivator and phosphatase 1 ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142 		JBrowse link
G Hoxa11 homeobox A11 ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 4:82,296,888...82,301,419
Ensembl chr 4:82,298,152...82,300,503
Ensembl chr 4:82,298,152...82,300,503 		JBrowse link
G Pax2 paired box 2 ISS
ISO		 GO_REF:0000024
(MGI:3768605|PMID:17785448)		 UniProt
RGD		 PMID:17785448 GO_REF:0000024 MGI:3768605 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329 		JBrowse link
G Six2 SIX homeobox 2 ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 6:8,952,572...8,955,893
Ensembl chr 6:8,952,572...8,956,276 		JBrowse link
muscle cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myl2 myosin light chain 2 IEA
ISO		 GO_REF:0000107
(MGI:67939|PMID:1379240)		 Ensembl
RGD		 PMID:1379240 GO_REF:0000107 MGI:67939 NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239 		JBrowse link
negative regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor ISO MGI:2449921 (MGI:3606816|PMID:16230531) RGD PMID:16230531 MGI:3606816 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371 		JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd7 frizzled class receptor 7 ISO (PMID:18681827) RGD PMID:18681827 NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550 		JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908 		JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035 		JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 ISO MGI:98956 (MGI:3711603|PMID:17462603) RGD PMID:17462603 MGI:3711603 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764 		JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsc goosecoid homeobox ISO (PMID:24290375) RGD PMID:24290375 NCBI chr 6:128,147,181...128,149,220
Ensembl chr 6:128,147,181...128,149,220 		JBrowse link
neuron fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISS
ISO		 GO_REF:0000024
MGI:1857470 (MGI:3639051|PMID:16469766), (MGI:5897542|PMID:24243019)		 UniProt
RGD		 PMID:16469766 PMID:24243019 GO_REF:0000024 MGI:3639051 MGI:5897542 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 IEA
ISO
ISS		 GO_REF:0000107
(MGI:3823133|PMID:18997111)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:18997111 GO_REF:0000024 GO_REF:0000107 MGI:3823133 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379 		JBrowse link
G Dmrta2 DMRT-like family A2 ISO (MGI:5013657|PMID:21576465) RGD PMID:21576465 MGI:5013657 NCBI chr 5:129,754,295...129,760,045
Ensembl chr 5:129,756,149...129,758,986 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO MGI:4418499 (MGI:5577209|PMID:24584053) RGD PMID:24584053 MGI:5577209 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 ISO MGI:102780 (MGI:5319720|PMID:22513373) RGD PMID:22513373 MGI:5319720 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142 		JBrowse link
G Fev FEV transcription factor, ETS family member ISO MGI:2449922 (MGI:4836772|PMID:20818386) RGD PMID:20818386 MGI:4836772 NCBI chr 9:82,142,981...82,146,855
Ensembl chr 9:82,142,981...82,146,874 		JBrowse link
G Foxa1 forkhead box A1 IEA
ISO		 GO_REF:0000107
MGI:1347476 (MGI:3720545|PMID:17596284)		 Ensembl
RGD		 PMID:17596284 GO_REF:0000107 MGI:3720545 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669 		JBrowse link
G Foxa2 forkhead box A2 ISO MGI:1347472|MGI:2176222|MGI:2177337 (MGI:3720545|PMID:17596284), (MGI:3767119|PMID:17922007) RGD PMID:17596284 PMID:17922007 MGI:3720545 MGI:3767119 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481 		JBrowse link
G Gsx2 GS homeobox 2 ISO MGI:2150162 (MGI:3579956|PMID:15930101) RGD PMID:15930101 MGI:3579956 NCBI chr14:35,650,985...35,652,709
Ensembl chr14:35,650,985...35,652,709 		JBrowse link
G Isl1 ISL LIM homeobox 1 ISO
IBA		 (MGI:3815381|PMID:18849985)
PMID:21873635		 RGD PMID:18849985, PMID:21873635 MGI:3815381, RGD:13792537 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436 		JBrowse link
G Isl2 ISL LIM homeobox 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:60,117,565...60,122,716
Ensembl chr 8:60,117,729...60,122,211 		JBrowse link
G Myt1l myelin transcription factor 1-like ISS
ISO		 GO_REF:0000024
(MGI:5897487|PMID:28379941), (MGI:5897542|PMID:24243019)		 UniProt
RGD		 PMID:24243019 PMID:28379941 GO_REF:0000024 MGI:5897487 MGI:5897542 NCBI chr 6:48,452,385...48,843,443
Ensembl chr 6:48,452,369...48,857,936 		JBrowse link
G Nkx2-2 NK2 homeobox 2 ISO MGI:1932100|MGI:97451 (MGI:3611719|PMID:16339193), (MGI:4360136|PMID:19592574) RGD PMID:16339193 PMID:19592574 MGI:3611719 MGI:4360136 NCBI chr 3:141,408,460...141,419,083
Ensembl chr 3:141,408,798...141,411,170 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 IMP RGD PMID:15247919 RGD:2325628 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503 		JBrowse link
G Pou3f2 POU class 3 homeobox 2 IEA
ISO
ISS		 GO_REF:0000107
(MGI:5897542|PMID:24243019)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24243019 GO_REF:0000024 GO_REF:0000107 MGI:5897542 NCBI chr 5:36,677,452...36,683,356
Ensembl chr 5:36,681,528...36,683,356 		JBrowse link
G Pou4f1 POU class 4 homeobox 1 IEA
ISO		 GO_REF:0000107
(MGI:4367920|PMID:19877281), (MGI:4454975|PMID:20096094)		 Ensembl
RGD		 PMID:19877281 PMID:20096094 GO_REF:0000107 MGI:4367920 MGI:4454975 NCBI chr15:88,618,255...88,622,712
Ensembl chr15:88,620,470...88,622,413 		JBrowse link
G Six1 SIX homeobox 1 ISO MGI:109344 (MGI:5319720|PMID:22513373) RGD PMID:22513373 MGI:5319720 NCBI chr 6:95,929,060...95,934,296
Ensembl chr 6:95,929,060...95,934,296 		JBrowse link
G Tlx3 T-cell leukemia, homeobox 3 ISO MGI:104867 (MGI:3607682|PMID:16234809) RGD PMID:16234809 MGI:3607682 NCBI chr10:18,128,869...18,131,745
Ensembl chr10:18,129,408...18,131,562 		JBrowse link
oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax6 paired box 6 IEA
ISO		 GO_REF:0000107
MGI:1856155 (MGI:1313099|PMID:9828088)		 Ensembl
RGD		 PMID:9828088 GO_REF:0000107 MGI:1313099 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624 		JBrowse link
G Sox6 SRY-box transcription factor 6 ISO MGI:2447148 (MGI:3693054|PMID:17084361) RGD PMID:17084361 MGI:3693054 NCBI chr 1:185,631,702...186,186,192
Ensembl chr 1:185,673,177...186,182,829 		JBrowse link
positive regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 ISO (PMID:18635606) RGD PMID:18635606 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor ISO MGI:2449921 (MGI:3606816|PMID:16230531) RGD PMID:16230531 MGI:3606816 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371 		JBrowse link
G Pax6 paired box 6 IMP RGD PMID:11880342 RGD:729590 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624 		JBrowse link
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908 		JBrowse link
G Wnt11 Wnt family member 11 ISO UniProtKB:P22725 (MGI:5424267|PMID:22569553) RGD PMID:22569553 MGI:5424267 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756 		JBrowse link
G Wnt5a Wnt family member 5A IEA
ISO		 GO_REF:0000107
UniProtKB:P48615 (MGI:5424267|PMID:22569553)		 Ensembl
RGD		 PMID:22569553 GO_REF:0000107 MGI:5424267 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860 		JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A ISO (PMID:20559569) RGD PMID:20559569 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035 		JBrowse link
regulation of cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox17 SRY-box transcription factor 17 ISO (MGI:3703823|PMID:17360443) RGD PMID:17360443 MGI:3703823 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907 		JBrowse link
regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmo4 LIM domain only 4 ISO MGI:3664560 (MGI:3840011|PMID:19323994) RGD PMID:19323994 MGI:3840011 NCBI chr 2:250,218,635...250,235,435
Ensembl chr 2:250,218,641...250,241,673 		JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607 		JBrowse link
regulation of heart induction by regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou5f1 POU class 5 homeobox 1 ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994 		JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esrp1 epithelial splicing regulatory protein 1 ISS
ISO		 GO_REF:0000024
(MGI:5915403|PMID:29107558)		 UniProt
RGD		 PMID:29107558 GO_REF:0000024 MGI:5915403 NCBI chr 5:24,576,988...24,631,758
Ensembl chr 5:24,576,991...24,631,698 		JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A ISO MGI:95522 (MGI:3702797|PMID:16943278) RGD PMID:16943278 MGI:3702797 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IEA
ISO		 GO_REF:0000107
MGI:1338938 (MGI:3702797|PMID:16943278)		 Ensembl
RGD		 PMID:16943278 GO_REF:0000107 MGI:3702797 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449 		JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A NOT ISO (MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:3040576 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512 		JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 ISO MGI:95729 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444 		JBrowse link
G Gli3 GLI family zinc finger 3 ISO MGI:95728 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:266,143,766...266,241,742
Ensembl chr 1:266,143,818...266,239,016 		JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 ISO MGI:95729 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444 		JBrowse link
G Gli3 GLI family zinc finger 3 ISO MGI:95728 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:266,143,766...266,241,742
Ensembl chr 1:266,143,818...266,239,016 		JBrowse link
spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxc10 homeo box C10 ISO MGI:96202 (MGI:3771768|PMID:18065432) RGD PMID:18065432 MGI:3771768 NCBI chr 7:144,577,578...144,582,802
Ensembl chr 7:144,577,465...144,582,622 		JBrowse link
G Hoxd10 homeo box D10 ISO MGI:96192 (MGI:3771768|PMID:18065432) RGD PMID:18065432 MGI:3771768 NCBI chr 3:61,614,133...61,617,342
Ensembl chr 3:61,613,774...61,617,367 		JBrowse link
G Isl1 ISL LIM homeobox 1 ISO MGI:102673 (MGI:4356383|PMID:19666821) RGD PMID:19666821 MGI:4356383 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436 		JBrowse link
G Isl2 ISL LIM homeobox 2 IEA
ISO		 GO_REF:0000107
MGI:102673 (MGI:4356383|PMID:19666821)		 Ensembl
RGD		 PMID:19666821 GO_REF:0000107 MGI:4356383 NCBI chr 8:60,117,565...60,122,716
Ensembl chr 8:60,117,729...60,122,211 		JBrowse link
G Lhx3 LIM homeobox 3 ISO MGI:101791|MGI:109156 (MGI:4356383|PMID:19666821) RGD PMID:19666821 MGI:4356383 NCBI chr 3:3,653,861...3,662,509
Ensembl chr 3:3,654,755...3,661,810 		JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 ISO
IBA		 MGI:2182358|MGI:2182361|MGI:2182363 (MGI:1344237|PMID:10482234)
PMID:21873635		 RGD PMID:10482234, PMID:21873635 MGI:1344237, RGD:13792537 NCBI chr 4:2,376,350...2,381,308
Ensembl chr 4:2,376,958...2,381,271 		JBrowse link
G Olig3 oligodendrocyte transcription factor 3 ISO MGI:3573868 (MGI:3531376|PMID:15769945) RGD PMID:15769945 MGI:3531376 NCBI chr 1:14,797,766...14,799,835
Ensembl chr 1:14,797,766...14,799,835 		JBrowse link
spinal cord oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO MGI:1857470 (MGI:3794240|PMID:18287202) RGD PMID:18287202 MGI:3794240 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510 		JBrowse link
G Nkx2-2 NK2 homeobox 2 ISO (MGI:3794240|PMID:18287202) RGD PMID:18287202 MGI:3794240 NCBI chr 3:141,408,460...141,419,083
Ensembl chr 3:141,408,798...141,411,170 		JBrowse link
G Olig2 oligodendrocyte transcription factor 2 ISO (MGI:3794240|PMID:18287202) RGD PMID:18287202 MGI:3794240 NCBI chr11:31,389,514...31,392,890
Ensembl chr11:31,389,514...31,392,890 		JBrowse link
stem cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox17 SRY-box transcription factor 17 ISO (MGI:4453910|PMID:20228271) RGD PMID:20228271 MGI:4453910 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907 		JBrowse link
G Sox18 SRY-box transcription factor 18 ISO (MGI:4453910|PMID:20228271) RGD PMID:20228271 MGI:4453910 NCBI chr 3:177,177,237...177,179,039
Ensembl chr 3:177,177,310...177,179,127 		JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 ISO MGI:2182329 (MGI:2136554|PMID:11239429) RGD PMID:11239429 MGI:2136554 NCBI chr 1:104,969,218...104,973,648
Ensembl chr 1:104,969,218...104,973,648 		JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 ISO MGI:4420993 (MGI:5435948|PMID:22932389) RGD PMID:22932389 MGI:5435948 NCBI chr 1:243,589,607...243,602,926
Ensembl chr 1:243,589,607...243,602,926 		JBrowse link
G Lhx3 LIM homeobox 3 ISO (MGI:4356383|PMID:19666821) RGD PMID:19666821 MGI:4356383 NCBI chr 3:3,653,861...3,662,509
Ensembl chr 3:3,654,755...3,661,810 		JBrowse link
G Shh sonic hedgehog signaling molecule IDA PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691 		JBrowse link
G Sox1 SRY-box transcription factor 1 ISO MGI:3653406 (MGI:4834949|PMID:20844123) RGD PMID:20844123 MGI:4834949
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    cellular process 18802
      cellular developmental process 4458
        cell fate specification 100
          abaxial cell fate specification 0
          anther wall tapetum cell fate specification 0
          bundle sheath cell fate specification 0
          cardiac cell fate specification + 3
          cell fate specification involved in pattern specification + 8
          compound eye cone cell fate specification + 0
          ectodermal cell fate specification + 1
          endodermal cell fate specification + 7
          endothelial cell fate specification + 3
          eosinophil fate specification 0
          epidermal cell fate specification + 3
          epithelial cell type specification, open tracheal system + 0
          glial cell fate specification + 5
          mesodermal cell fate specification + 12
          muscle cell fate specification + 1
          myoblast fate specification + 0
          negative regulation of cell fate specification + 6
          neuroblast fate specification 0
          neuron fate specification + 32
          plant epidermal cell fate specification + 0
          positive regulation of cell fate specification + 4
          regulation of cell fate specification + 17
          skeletal muscle satellite cell fate specification 0
          stem cell fate specification + 4
          vulval cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 20030
    cellular process 18802
      cellular developmental process 4458
        cell differentiation 4363
          cell fate commitment 282
            cell fate specification 100
              abaxial cell fate specification 0
              anther wall tapetum cell fate specification 0
              bundle sheath cell fate specification 0
              cardiac cell fate specification + 3
              cell fate specification involved in pattern specification + 8
              compound eye cone cell fate specification + 0
              ectodermal cell fate specification + 1
              endodermal cell fate specification + 7
              endothelial cell fate specification + 3
              eosinophil fate specification 0
              epidermal cell fate specification + 3
              epithelial cell type specification, open tracheal system + 0
              glial cell fate specification + 5
              mesodermal cell fate specification + 12
              muscle cell fate specification + 1
              myoblast fate specification + 0
              negative regulation of cell fate specification + 6
              neuroblast fate specification 0
              neuron fate specification + 32
              plant epidermal cell fate specification + 0
              positive regulation of cell fate specification + 4
              regulation of cell fate specification + 17
              skeletal muscle satellite cell fate specification 0
              stem cell fate specification + 4
              vulval cell fate specification 0
paths to the root