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ONTOLOGY REPORT - ANNOTATIONS

Term:cell fate specification
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Accession:GO:0001708 term browser browse the term
Definition:The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.

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cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98297 (MGI:3624618|PMID:16647304)		 Ensembl
RGD		 PMID:16647304 GO_REF:0000107 MGI:3624618 NCBI chr 8:33,775,123...33,861,635
Ensembl chr 8:33,806,183...33,859,033 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2148591|MGI:2148594|MGI:2450929 (MGI:3578464|PMID:15866163)		 Ensembl
RGD		 PMID:15866163 GO_REF:0000107 MGI:3578464 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dhh desert hedgehog signaling molecule involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Eomes eomesodermin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 acts_upstream_of_or_within ISO MGI:3042750 (MGI:3039989|PMID:15105374), (MGI:3806189|PMID:18590716) RGD PMID:15105374 PMID:18590716 MGI:3039989 MGI:3806189 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612 		JBrowse link
G Foxa2 forkhead box A2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(MGI:3772421|PMID:18076286)		 ParkinsonsUK-UCL
RGD		 PMID:18076286 GO_REF:0000024 MGI:3772421 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Ihh Indian hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1934258 (MGI:3807419|PMID:18582859)
PMID:21873635		 RGD PMID:18582859 PMID:21873635 MGI:3807419, RGD:13792537 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2154539 (MGI:84974|PMID:9004034)		 Ensembl
RGD		 PMID:9004034 GO_REF:0000107 MGI:84974 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Mga MAX dimerization protein MGA involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:106,851,216...106,942,908
Ensembl chr 3:106,851,140...106,941,043 		JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:2178778 (MGI:3042356|PMID:15068794) RGD PMID:15068794 MGI:3042356 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO MGI:2176222|MGI:2661065 (MGI:3578035|PMID:15888661) RGD PMID:15888661 MGI:3578035 NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (MGI:2137782|PMID:10367888) RGD PMID:10367888 MGI:2137782 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Prdm14 PR/SET domain 14 acts_upstream_of_or_within ISO MGI:3805889 (MGI:3805418|PMID:18622394) RGD PMID:18622394 MGI:3805418 NCBI chr 5:6,082,163...6,092,712
Ensembl chr 5:6,082,442...6,092,712 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:109284 (MGI:3513219|PMID:15525534) RGD PMID:15525534 MGI:3513219 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (MGI:3513219|PMID:15525534) RGD PMID:15525534 MGI:3513219 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO
ISS		 GO_REF:0000107
PMID:21873635
MGI:1857796|MGI:1926387 (MGI:2387225|PMID:12231626), (MGI:3624618|PMID:16647304), (MGI:3772421|PMID:18076286)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12231626 PMID:16647304 PMID:18076286 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:2387225 MGI:3624618 MGI:3772421, RGD:13792537 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176255 (MGI:3806189|PMID:18590716)		 Ensembl
RGD		 PMID:18590716 GO_REF:0000107 MGI:3806189 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO MGI:2449045 (MGI:2448211|PMID:12514105) RGD PMID:12514105 MGI:2448211 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2429649 (MGI:2667289|PMID:12842915)		 UniProt
RGD		 PMID:12842915 GO_REF:0000024 MGI:2667289 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tbr1 T-box brain transcription factor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:46,350,237...46,368,397
Ensembl chr 3:46,351,213...46,361,041 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within		 IBA
ISO
ISS		 PMID:21873635
MGI:1351209|MGI:2179191 (MGI:3039048|PMID:15084464), (MGI:3044254|PMID:15064766)
GO_REF:0000024		 RGD
UniProt		 PMID:15064766 PMID:15084464 PMID:21873635 GO_REF:0000024 MGI:3039048 MGI:3044254, RGD:13792537 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380 		JBrowse link
G Tbx10 T-box transcription factor 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:201,285,729...201,292,676
Ensembl chr 1:201,279,829...201,292,601 		JBrowse link
G Tbx15 T-box transcription factor 15 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:186,576,347...186,687,748
Ensembl chr 2:186,576,676...186,687,663 		JBrowse link
G Tbx18 T-box transcription factor 18 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058 		JBrowse link
G Tbx19 T-box transcription factor 19 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:77,450,848...77,484,475
Ensembl chr13:77,450,849...77,504,163 		JBrowse link
G Tbx2 T-box transcription factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Tbx22 T-box transcription factor 22 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:72,723,619...72,774,647
Ensembl chr  X:72,723,617...72,774,647 		JBrowse link
G Tbx3 T-box transcription factor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
G Tbx4 T-box transcription factor 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:70,730,686...70,760,829
Ensembl chr10:70,731,163...70,760,825 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
G Tbx6 T-box transcription factor 6 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2447721 (MGI:2447720|PMID:9490412)		 RGD PMID:9490412 PMID:21873635 MGI:2447720, RGD:13792537 NCBI chr 1:181,387,851...181,392,762
Ensembl chr 1:181,388,684...181,392,593 		JBrowse link
G Tbxt T-box transcription factor T involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:52,298,099...52,309,813
Ensembl chr 1:52,298,099...52,305,864 		JBrowse link
G Tead4 TEA domain transcription factor 4 acts_upstream_of_or_within ISO MGI:106907 (MGI:3770613|PMID:18083014) RGD PMID:18083014 MGI:3770613 NCBI chr 4:161,474,122...161,572,837
Ensembl chr 4:161,497,851...161,572,323 		JBrowse link
G Tlx3 T-cell leukemia, homeobox 3 acts_upstream_of_or_within ISO MGI:2180105|MGI:98769 (MGI:3044254|PMID:15064766) RGD PMID:15064766 MGI:3044254 NCBI chr10:17,789,706...17,792,207
Ensembl chr10:17,790,053...17,792,207 		JBrowse link
activation of prostate induction by androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3716756 (MGI:3714080|PMID:17317769)		 Ensembl
RGD		 PMID:17317769 GO_REF:0000107 MGI:3714080 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:2155983 (MGI:1339217|PMID:10364557) RGD PMID:10364557 MGI:1339217 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154 		JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO (MGI:2677178|PMID:14511481) RGD PMID:14511481 MGI:2677178 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO UniProtKB:P52800 (MGI:3056004|PMID:15466160) RGD PMID:15466160 MGI:3056004 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
BMP signaling pathway involved in mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etv2 ETS variant transcription factor 2 acts_upstream_of_or_within ISO (MGI:4415813|PMID:18462699) RGD PMID:18462699 MGI:4415813 NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431 		JBrowse link
cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tenm4 teneurin transmembrane protein 4 acts_upstream_of_or_within ISO MGI:3655239 (MGI:5429684|PMID:17350578) RGD PMID:17350578 MGI:5429684 NCBI chr 1:149,895,097...151,263,315
Ensembl chr 1:150,780,381...151,259,144 		JBrowse link
endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3774028 (MGI:4887279|PMID:21245162)		 RGD PMID:21245162 PMID:21873635 MGI:4887279, RGD:13792537 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Hnf1b HNF1 homeobox B acts_upstream_of_or_within ISO MGI:1857856 (MGI:3807614|PMID:18635606) RGD PMID:18635606 MGI:3807614 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888 		JBrowse link
G Nanog Nanog homeobox acts_upstream_of_or_within ISO (PMID:20713518) RGD PMID:20713518 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:20713518) RGD PMID:20713518 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO (MGI:4946573|PMID:21305474) RGD PMID:21305474 MGI:4946573 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:21245162) RGD PMID:21245162 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa13 homeo box A13 acts_upstream_of_or_within ISO MGI:2152356 (MGI:3797428|PMID:18483557) RGD PMID:18483557 MGI:3797428 NCBI chr 4:81,358,956...81,361,091
Ensembl chr 4:81,358,956...81,361,091 		JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5466218|PMID:22282195)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22282195 GO_REF:0000024 GO_REF:0000107 MGI:5466218 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
epidermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1095405 (MGI:5571965|PMID:24492243) RGD PMID:24492243 MGI:5571965 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Ptch2 patched 2 acts_upstream_of_or_within ISO MGI:105373 (MGI:5571965|PMID:24492243) RGD PMID:24492243 MGI:5571965 NCBI chr 5:130,571,956...130,592,506
Ensembl chr 5:130,572,312...130,592,405 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:1926500|MGI:3583755 (MGI:3689772|PMID:17079689) RGD PMID:17079689 MGI:3689772 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Hoxa11 homeobox A11 involved_in ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232 		JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3768605|PMID:17785448)		 UniProt
RGD		 PMID:17785448 GO_REF:0000024 MGI:3768605 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Six2 SIX homeobox 2 involved_in ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193 		JBrowse link
muscle cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myl2 myosin light chain 2 acts_upstream_of_or_within ISO (MGI:67939|PMID:1379240) RGD PMID:1379240 MGI:67939 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983 		JBrowse link
negative regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO MGI:2449921 (MGI:3606816|PMID:16230531) RGD PMID:16230531 MGI:3606816 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd7 frizzled class receptor 7 involved_in ISO (PMID:18681827) RGD PMID:18681827 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781 		JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:98956 (MGI:3711603|PMID:17462603) RGD PMID:17462603 MGI:3711603 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsc goosecoid homeobox involved_in ISO (PMID:24290375) RGD PMID:24290375 NCBI chr 6:123,388,072...123,390,111
Ensembl chr 6:123,388,072...123,390,111 		JBrowse link
neuron fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857470 (MGI:3639051|PMID:16469766)
(MGI:5897542|PMID:24243019)		 UniProt
RGD		 PMID:16469766 PMID:24243019 GO_REF:0000024 MGI:3639051 MGI:5897542 NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3823133|PMID:18997111)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18997111 GO_REF:0000024 GO_REF:0000107 MGI:3823133 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dmrta2 DMRT-like family A2 acts_upstream_of_or_within ISO (MGI:5013657|PMID:21576465) RGD PMID:21576465 MGI:5013657 NCBI chr 5:124,805,883...124,811,694
Ensembl chr 5:124,805,883...124,811,630 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 acts_upstream_of_or_within ISO MGI:4418499 (MGI:5577209|PMID:24584053) RGD PMID:24584053 MGI:5577209 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of_or_within ISO MGI:102780 (MGI:5319720|PMID:22513373) RGD PMID:22513373 MGI:5319720 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Fev FEV transcription factor, ETS family member acts_upstream_of_or_within ISO MGI:2449922 (MGI:4836772|PMID:20818386) RGD PMID:20818386 MGI:4836772 NCBI chr 9:76,439,164...76,443,603
Ensembl chr 9:76,439,172...76,443,065 		JBrowse link
G Foxa1 forkhead box A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1347476 (MGI:3720545|PMID:17596284)		 Ensembl
RGD		 PMID:17596284 GO_REF:0000107 MGI:3720545 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO MGI:1347472|MGI:2176222|MGI:2177337 (MGI:3720545|PMID:17596284), (MGI:3767119|PMID:17922007) RGD PMID:17596284 PMID:17922007 MGI:3720545 MGI:3767119 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Gsx2 GS homeobox 2 acts_upstream_of_or_within ISO MGI:2150162 (MGI:3579956|PMID:15930101) RGD PMID:15930101 MGI:3579956 NCBI chr14:33,123,799...33,126,151
Ensembl chr14:33,124,381...33,126,105 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in IBA
ISO		 PMID:21873635
(MGI:3815381|PMID:18849985)		 RGD PMID:18849985 PMID:21873635 MGI:3815381, RGD:13792537 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Isl2 ISL LIM homeobox 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:55,923,805...55,928,790
Ensembl chr 8:55,923,805...55,928,790 		JBrowse link
G Myt1l myelin transcription factor 1-like involved_in ISS
ISO		 GO_REF:0000024
(MGI:5897487|PMID:28379941), (MGI:5897542|PMID:24243019)		 UniProt
RGD		 PMID:24243019 PMID:28379941 GO_REF:0000024 MGI:5897487 MGI:5897542 NCBI chr 6:46,164,742...46,564,234
Ensembl chr 6:46,428,150...46,561,671 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100|MGI:97451 (MGI:3611719|PMID:16339193), (MGI:4360136|PMID:19592574) RGD PMID:16339193 PMID:19592574 MGI:3611719 MGI:4360136 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 IMP RGD PMID:15247919 RGD:2325628 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Pou3f2 POU class 3 homeobox 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5897542|PMID:24243019)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24243019 GO_REF:0000024 GO_REF:0000107 MGI:5897542 NCBI chr 5:36,077,930...36,083,838
Ensembl chr 5:36,077,930...36,083,838 		JBrowse link
G Pou4f1 POU class 4 homeobox 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4367920|PMID:19877281), (MGI:4454975|PMID:20096094)		 Ensembl
RGD		 PMID:19877281 PMID:20096094 GO_REF:0000107 MGI:4367920 MGI:4454975 NCBI chr15:81,255,566...81,260,057
Ensembl chr15:81,257,781...81,259,728 		JBrowse link
G Six1 SIX homeobox 1 acts_upstream_of_or_within ISO MGI:109344 (MGI:5319720|PMID:22513373) RGD PMID:22513373 MGI:5319720 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975 		JBrowse link
G Tlx3 T-cell leukemia, homeobox 3 acts_upstream_of_or_within ISO MGI:104867 (MGI:3607682|PMID:16234809) RGD PMID:16234809 MGI:3607682 NCBI chr10:17,789,706...17,792,207
Ensembl chr10:17,790,053...17,792,207 		JBrowse link
oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856155 (MGI:1313099|PMID:9828088)		 Ensembl
RGD		 PMID:9828088 GO_REF:0000107 MGI:1313099 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Sox6 SRY-box transcription factor 6 acts_upstream_of_or_within ISO MGI:2447148 (MGI:3693054|PMID:17084361) RGD PMID:17084361 MGI:3693054 NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386 		JBrowse link
positive regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:18635606) RGD PMID:18635606 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of_or_within ISO MGI:2449921 (MGI:3606816|PMID:16230531) RGD PMID:16230531 MGI:3606816 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
G Pax6 paired box 6 IMP RGD PMID:11880342 RGD:729590 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Wnt11 Wnt family member 11 involved_in ISO UniProtKB:P22725 (MGI:5424267|PMID:22569553) RGD PMID:22569553 MGI:5424267 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294 		JBrowse link
G Wnt5a Wnt family member 5A involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P48615 (MGI:5424267|PMID:22569553)		 Ensembl
RGD		 PMID:22569553 GO_REF:0000107 MGI:5424267 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
regulation of cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox17 SRY-box transcription factor 17 involved_in ISO (MGI:3703823|PMID:17360443) RGD PMID:17360443 MGI:3703823 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
regulation of cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmo4 LIM domain only 4 acts_upstream_of_or_within ISO MGI:3664560 (MGI:3840011|PMID:19323994) RGD PMID:19323994 MGI:3840011 NCBI chr 2:233,264,180...233,280,881
Ensembl chr 2:233,264,182...233,280,880 		JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
regulation of heart induction by regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esrp1 epithelial splicing regulatory protein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5915403|PMID:29107558)		 UniProt
RGD		 PMID:29107558 GO_REF:0000024 MGI:5915403 NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062 		JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO MGI:95522 (MGI:3702797|PMID:16943278) RGD PMID:16943278 MGI:3702797 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:1338938 (MGI:3702797|PMID:16943278) RGD PMID:16943278 MGI:3702797 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A NOT|involved_in ISO (MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:3040576 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxc10 homeo box C10 acts_upstream_of_or_within ISO MGI:96202 (MGI:3771768|PMID:18065432) RGD PMID:18065432 MGI:3771768 NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:134,103,643...134,108,966 		JBrowse link
G Hoxd10 homeo box D10 acts_upstream_of_or_within ISO MGI:96192 (MGI:3771768|PMID:18065432) RGD PMID:18065432 MGI:3771768 NCBI chr 3:59,594,516...59,597,725
Ensembl chr 3:59,594,516...59,597,725 		JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO MGI:102673 (MGI:4356383|PMID:19666821) RGD PMID:19666821 MGI:4356383 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Isl2 ISL LIM homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:102673 (MGI:4356383|PMID:19666821)		 Ensembl
RGD		 PMID:19666821 GO_REF:0000107 MGI:4356383 NCBI chr 8:55,923,805...55,928,790
Ensembl chr 8:55,923,805...55,928,790 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO MGI:101791|MGI:109156 (MGI:4356383|PMID:19666821) RGD PMID:19666821 MGI:4356383 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2182358|MGI:2182361|MGI:2182363 (MGI:1344237|PMID:10482234)		 RGD PMID:10482234 PMID:21873635 MGI:1344237, RGD:13792537 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465 		JBrowse link
G Olig3 oligodendrocyte transcription factor 3 acts_upstream_of_or_within ISO MGI:3573868 (MGI:3531376|PMID:15769945) RGD PMID:15769945 MGI:3531376 NCBI chr 1:14,081,259...14,083,336
Ensembl chr 1:14,081,328...14,082,149 		JBrowse link
spinal cord oligodendrocyte cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857470 (MGI:3794240|PMID:18287202) RGD PMID:18287202 MGI:3794240 NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO (MGI:3794240|PMID:18287202) RGD PMID:18287202 MGI:3794240 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Olig2 oligodendrocyte transcription factor 2 acts_upstream_of_or_within ISO (MGI:3794240|PMID:18287202) RGD PMID:18287202 MGI:3794240 NCBI chr11:30,475,510...30,478,886
Ensembl chr11:30,475,398...30,480,152 		JBrowse link
stem cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO (MGI:4453910|PMID:20228271) RGD PMID:20228271 MGI:4453910 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox18 SRY-box transcription factor 18 acts_upstream_of_or_within ISO (MGI:4453910|PMID:20228271) RGD PMID:20228271 MGI:4453910 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290 		JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 acts_upstream_of_or_within ISO MGI:2182329 (MGI:2136554|PMID:11239429) RGD PMID:11239429 MGI:2136554 NCBI chr 1:99,349,608...99,354,038
Ensembl chr 1:99,349,608...99,354,038 		JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 acts_upstream_of_or_within ISO MGI:4420993 (MGI:5435948|PMID:22932389) RGD PMID:22932389 MGI:5435948 NCBI chr 1:223,244,340...223,264,254
Ensembl chr 1:223,248,747...223,262,530 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO (MGI:4356383|PMID:19666821) RGD PMID:19666821 MGI:4356383 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within IDA PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sox1 SRY-box transcription factor 1 acts_upstream_of_or_within ISO MGI:3653406 (MGI:4834949|PMID:20844123) RGD PMID:20844123 MGI:4834949 NCBI chr16:77,134,795...77,139,628 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cellular developmental process 4478
        cell fate specification 100
          abaxial cell fate specification 0
          anther wall tapetum cell fate specification 0
          bundle sheath cell fate specification 0
          cardiac cell fate specification + 3
          cell fate specification involved in pattern specification + 8
          compound eye cone cell fate specification + 0
          ectodermal cell fate specification + 1
          endodermal cell fate specification + 8
          endothelial cell fate specification + 3
          eosinophil fate specification 0
          epidermal cell fate specification + 3
          epithelial cell type specification, open tracheal system + 0
          glial cell fate specification + 5
          mesodermal cell fate specification + 12
          muscle cell fate specification + 1
          myoblast fate specification + 0
          negative regulation of cell fate specification + 6
          neuroblast fate specification 0
          neuron fate specification + 32
          plant epidermal cell fate specification + 0
          positive regulation of cell fate specification + 4
          regulation of cell fate specification + 17
          skeletal muscle satellite cell fate specification 0
          stem cell fate specification + 4
          vulval cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cellular developmental process 4478
        cell differentiation 4383
          cell fate commitment 283
            cell fate specification 100
              abaxial cell fate specification 0
              anther wall tapetum cell fate specification 0
              bundle sheath cell fate specification 0
              cardiac cell fate specification + 3
              cell fate specification involved in pattern specification + 8
              compound eye cone cell fate specification + 0
              ectodermal cell fate specification + 1
              endodermal cell fate specification + 8
              endothelial cell fate specification + 3
              eosinophil fate specification 0
              epidermal cell fate specification + 3
              epithelial cell type specification, open tracheal system + 0
              glial cell fate specification + 5
              mesodermal cell fate specification + 12
              muscle cell fate specification + 1
              myoblast fate specification + 0
              negative regulation of cell fate specification + 6
              neuroblast fate specification 0
              neuron fate specification + 32
              plant epidermal cell fate specification + 0
              positive regulation of cell fate specification + 4
              regulation of cell fate specification + 17
              skeletal muscle satellite cell fate specification 0
              stem cell fate specification + 4
              vulval cell fate specification 0
paths to the root