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ONTOLOGY REPORT - ANNOTATIONS


Term:long-chain fatty acid metabolic process
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Accession:GO:0001676 term browser browse the term
Definition:The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
Synonyms:exact_synonym: long-chain fatty acid metabolism


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long-chain fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acad9 acyl-CoA dehydrogenase family member 9 involved_in ISO (PMID:16020546) BHF-UCL PMID:16020546 NCBI chrNW_004936798:83,952...106,381 JBrowse link
G Acot4 acyl-CoA thioesterase 4 involved_in ISO (PMID:16940157) HGNC-UCL PMID:16940157 NCBI chrNW_004936488:2,912,016...2,914,995 JBrowse link
G Acot9 acyl-CoA thioesterase 9 involved_in ISO (MGI:6718236|PMID:23864032) UniProt PMID:23864032 MGI:6718236 NCBI chrNW_004936624:795,272...834,441 JBrowse link
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 involved_in ISO (PMID:10954726), (PMID:24269233) UniProt PMID:10954726 PMID:24269233 NCBI chrNW_004936471:36,767,656...36,822,677 JBrowse link
G Acsl1 acyl-CoA synthetase long chain family member 1 involved_in ISO (PMID:22022213), (PMID:24269233)
PMID:10749848
PMID:28209804
UniProt PMID:10749848 PMID:22022213 PMID:24269233 PMID:28209804 RGD:14697717 RGD:14697721 NCBI chrNW_004936554:4,425,518...4,484,853 JBrowse link
G Acsl3 acyl-CoA synthetase long chain family member 3 involved_in ISO (PMID:22633490)
PMID:28209804
UniProt PMID:22633490 PMID:28209804 RGD:14697717 NCBI chrNW_004936569:4,774,602...4,842,906 JBrowse link
G Acsl4 acyl-CoA synthetase long chain family member 4 involved_in ISO (PMID:22633490)
PMID:28209804
(PMID:24269233)
UniProt PMID:22633490 PMID:24269233 PMID:28209804 RGD:14697717 NCBI chrNW_004936499:5,456,985...5,540,115 JBrowse link
G Acsl5 acyl-CoA synthetase long chain family member 5 involved_in ISO PMID:22633490
(MGI:6355833|PMID:22633490)
PMID:28209804
(PMID:22633490)
(PMID:17681178), (PMID:24269233)
UniProt PMID:17681178 PMID:22633490 PMID:24269233 PMID:28209804 MGI:6355833 RGD:14697717 RGD:14697723 NCBI chrNW_004936486:2,952,379...2,992,148 JBrowse link
G Acsl6 acyl-CoA synthetase long chain family member 6 involved_in ISO PMID:28209804
(PMID:20429931), (PMID:24269233)
(PMID:22633490)
RGD
UniProt
PMID:1569043 PMID:20429931 PMID:22633490 PMID:24269233 PMID:28209804 RGD:14697717 RGD:69376 NCBI chrNW_004936647:3,153,586...3,208,935 JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:15161924 RGD:1598388 NCBI chrNW_004936810:791,823...838,303 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A involved_in ISO PMID:21990363
(PMID:11350182)
RGD
UniProt
PMID:11350182 PMID:19302064 PMID:21990363 RGD:2311346 RGD:8554544 NCBI chrNW_004936599:1,491,934...1,535,101 JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 involved_in ISO (PMID:20538056) UniProt PMID:20538056 NCBI chrNW_004936522:7,858,172...7,875,679 JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase ISO N-myristoylglycine RGD PMID:8660675 RGD:6483540 NCBI chrNW_004936523:1,492,795...1,786,942 JBrowse link
G Pnpla3 patatin like phospholipase domain containing 3 involved_in ISO (PMID:22560221)
(MGI:5426312|PMID:22560221)
BHF-UCL PMID:22560221 MGI:5426312 NCBI chrNW_004936718:1,620,034...1,638,315 JBrowse link
G Slc27a2 solute carrier family 27 member 2 involved_in
acts_upstream_of_or_within
ISO PMID:10640429
(MGI:2183868|PMID:12048192)
(PMID:22022213)
UniProt
MGI
PMID:10640429 PMID:12048192 PMID:22022213 MGI:2183868 RGD:8554430 NCBI chrNW_004936471:12,259,779...12,298,760 JBrowse link
G Slc27a3 solute carrier family 27 member 3 involved_in ISO (PMID:23936004) UniProt PMID:23936004 NCBI chrNW_004936580:3,554,826...3,559,201 JBrowse link
G Slc27a4 solute carrier family 27 member 4 involved_in
acts_upstream_of_or_within
ISO (PMID:22022213)
(MGI:2136504|PMID:11404000), (MGI:3576956|PMID:15653672)
UniProt
MGI
PMID:11404000 PMID:15653672 PMID:22022213 MGI:2136504 MGI:3576956 NCBI chrNW_004936487:15,877,075...15,905,752 JBrowse link
arachidonic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in ISO (PMID:15629692)
(MGI:3608217|PMID:16129665)
(MGI:1313249|PMID:10100631), (MGI:6316908|PMID:11256953)
PMID:23382512
UniProt PMID:10100631 PMID:11256953 PMID:15629692 PMID:16129665 PMID:23382512 MGI:1313249 MGI:3608217 MGI:6316908 RGD:8554649 NCBI chrNW_004936595:1,310,556...1,321,974 JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in ISO (MGI:1101294|PMID:8798642)
(MGI:66203|PMID:8188678)
(PMID:17052953), (PMID:1944593), (PMID:24282679), (PMID:8334154)
PMID:23382512
RGD
UniProt
PMID:1944593 PMID:8117750 PMID:8188678 PMID:8334154 PMID:8798642 More... MGI:1101294 MGI:66203 RGD:70288 RGD:8554649 NCBI chrNW_004936677:3,232,183...3,241,307 JBrowse link
G Alox15b arachidonate 15-lipoxygenase type B involved_in ISO (PMID:10542053), (PMID:10625675), (PMID:24282679), (PMID:24497644), (PMID:27145229), (PMID:9177185)
(MGI:1097306|PMID:9305900)
PMID:23382512
UniProt PMID:9177185 PMID:9305900 PMID:10542053 PMID:10625675 PMID:23382512 More... MGI:1097306 RGD:8554649 NCBI chrNW_004936595:1,279,944...1,288,321 JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISO (PMID:12881489), (PMID:17045234)
(MGI:3694035|PMID:17045234)
PMID:23382512
UniProt PMID:12881489 PMID:17045234 PMID:23382512 MGI:3694035 RGD:8554649 NCBI chrNW_004936595:1,329,492...1,350,914 JBrowse link
G Dagla diacylglycerol lipase alpha involved_in
acts_upstream_of_or_within
ISO (PMID:14610053)
(MGI:4437165|PMID:20147530)
(MGI:6423248|PMID:17584991)
UniProt
MGI
PMID:14610053 PMID:17584991 PMID:20147530 MGI:4437165 MGI:6423248 NCBI chrNW_004936581:1,371,292...1,430,699 JBrowse link
G Daglb diacylglycerol lipase beta involved_in
acts_upstream_of_or_within
ISO (PMID:14610053)
(MGI:4437165|PMID:20147530)
(MGI:6414691|PMID:23103940)
UniProt
MGI
PMID:14610053 PMID:20147530 PMID:23103940 MGI:4437165 MGI:6414691 NCBI chrNW_004936750:17,411...105,436 JBrowse link
G Ephx1 epoxide hydrolase 1 involved_in ISO (PMID:24958911) UniProt PMID:24958911 NCBI chrNW_004936526:2,589,254...2,652,831 JBrowse link
G Fads1 fatty acid desaturase 1 ISO RGD PMID:11414679 RGD:632758 NCBI chrNW_004936581:1,312,199...1,327,046 JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO (PMID:11115402)
(MGI:893248|PMID:9195979)
UniProt PMID:9195979 PMID:11115402 MGI:893248 NCBI chrNW_004936529:997,943...999,123 JBrowse link
G Gpx4 glutathione peroxidase 4 involved_in ISO (PMID:11115402) UniProt PMID:11115402 NCBI chrNW_004936588:506,101...508,469 JBrowse link
G LOC101961588 cytochrome P450 2D17 ISO RGD PMID:10945868 RGD:1599723 NCBI chrNW_004936718:153,340...157,966 JBrowse link
G LOC101970101 cytochrome P450 1B1 involved_in ISO (PMID:15258110)
(MGI:5572883|PMID:15258110)
UniProt PMID:15258110 MGI:5572883 NCBI chrNW_004936663:345,021...355,188 JBrowse link
G LOC101975825 group IIF secretory phospholipase A2 involved_in ISO (MGI:6467677|PMID:11877435) UniProt PMID:11877435 MGI:6467677 NCBI chrNW_004936474:6,186,604...6,192,621 JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO RGD PMID:15027896 RGD:1626220 NCBI chrNW_004936501:12,342,670...12,390,650 JBrowse link
G Mgll monoglyceride lipase involved_in ISO (MGI:4836780|PMID:20729846) UniProt PMID:20729846 MGI:4836780 NCBI chrNW_004936798:681,549...721,645 JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in ISO (PMID:7794891) RGD
UniProt
PMID:7794891 PMID:16603549 RGD:1642459 NCBI chrNW_004936481:3,559,377...3,689,797 JBrowse link
G Pnpla8 patatin like phospholipase domain containing 8 involved_in ISO (PMID:10833412), (PMID:15695510), (PMID:28442572) UniProt PMID:10833412 PMID:15695510 PMID:28442572 NCBI chrNW_004936653:1,470,314...1,499,813 JBrowse link
cyclooxygenase pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb1 bradykinin receptor B1 involved_in ISO (PMID:23846981) AgBase PMID:23846981 NCBI chrNW_004936604:551,774...567,014 JBrowse link
G LOC101974307 protein SCO1 homolog, mitochondrial acts_upstream_of_or_within ISO (MGI:6093414|PMID:28973536) MGI PMID:28973536 MGI:6093414 NCBI chrNW_004936595:3,523,789...3,537,933 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 involved_in ISO (PMID:1380156) BHF-UCL PMID:1380156 NCBI chrNW_004936487:10,745,465...10,758,812 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in
acts_upstream_of_or_within
ISO (PMID:1380156), (PMID:7592599), (PMID:7947975)
(MGI:5315361|PMID:12925531)
(MGI:52337|PMID:1419907)
UniProt
MGI
PMID:1380156 PMID:1419907 PMID:7592599 PMID:7947975 PMID:12925531 MGI:52337 MGI:5315361 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Sphk1 sphingosine kinase 1 ISO RGD PMID:18723875 RGD:2311353 NCBI chrNW_004936594:1,482,830...1,489,337 JBrowse link
hepoxilin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in ISO PMID:23382512 UniProt PMID:23382512 RGD:8554649 NCBI chrNW_004936595:1,310,556...1,321,974 JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in ISO PMID:23382512 RGD
UniProt
PMID:15123652 PMID:23382512 RGD:5509794 RGD:8554649 NCBI chrNW_004936677:3,232,183...3,241,307 JBrowse link
G Alox15b arachidonate 15-lipoxygenase type B involved_in ISO PMID:23382512 UniProt PMID:23382512 RGD:8554649 NCBI chrNW_004936595:1,279,944...1,288,321 JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISO (PMID:12881489), (PMID:17045234)
(MGI:5488571|PMID:22832496)
(MGI:3694035|PMID:17045234)
PMID:23382512
UniProt PMID:12881489 PMID:17045234 PMID:22832496 PMID:23382512 MGI:3694035 MGI:5488571 RGD:8554649 NCBI chrNW_004936595:1,329,492...1,350,914 JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO (PMID:21046276) UniProt PMID:21046276 NCBI chrNW_004936599:2,197,681...2,200,642 JBrowse link
linoleic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in ISO (MGI:3608217|PMID:16129665) UniProt PMID:16129665 MGI:3608217 NCBI chrNW_004936595:1,310,556...1,321,974 JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in ISO (PMID:8334154) UniProt PMID:8334154 NCBI chrNW_004936677:3,232,183...3,241,307 JBrowse link
G Alox15b arachidonate 15-lipoxygenase type B involved_in ISO (MGI:1097306|PMID:9305900) UniProt PMID:9305900 MGI:1097306 NCBI chrNW_004936595:1,279,944...1,288,321 JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISO (PMID:12881489), (PMID:17045234)
(MGI:3694035|PMID:17045234)
UniProt PMID:12881489 PMID:17045234 MGI:3694035 NCBI chrNW_004936595:1,329,492...1,350,914 JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:16962614 RGD:5688387 NCBI chrNW_004936675:350,357...392,919 JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO (PMID:16624487) BHF-UCL PMID:16624487 NCBI chrNW_004936599:2,197,681...2,200,642 JBrowse link
G Pnpla8 patatin like phospholipase domain containing 8 involved_in ISO (PMID:15695510) UniProt PMID:15695510 NCBI chrNW_004936653:1,470,314...1,499,813 JBrowse link
long-chain fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 ISO RGD PMID:11381125 RGD:68727 NCBI chrNW_004936471:36,767,656...36,822,677 JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 involved_in ISO (PMID:20937905) UniProt PMID:20937905 NCBI chrNW_004936563:1,224,392...1,344,707 JBrowse link
G Fads1 fatty acid desaturase 1 acts_upstream_of_or_within ISO (PMID:10601301) MGI PMID:10601301 NCBI chrNW_004936581:1,312,199...1,327,046 JBrowse link
G LOC101958900 glutathione S-transferase Mu 1 involved_in ISO (PMID:27791009) UniProt PMID:27791009 NCBI chrNW_004936704:1,142,990...1,150,491 JBrowse link
G Ltc4s leukotriene C4 synthase involved_in ISO (PMID:27791009) UniProt PMID:27791009 NCBI chrNW_004936739:975,494...978,426 JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within ISO (MGI:3619818|PMID:1150661) MGI PMID:1150661 MGI:3619818 NCBI chrNW_004936471:14,105,832...14,257,386 JBrowse link
G Plp1 proteolipid protein 1 acts_upstream_of_or_within ISO (MGI:3619818|PMID:1150661) MGI PMID:1150661 MGI:3619818 NCBI chrNW_004936499:10,534,953...10,553,411 JBrowse link
G Qki QKI, KH domain containing RNA binding acts_upstream_of_or_within ISO (MGI:3619818|PMID:1150661) MGI PMID:1150661 MGI:3619818 NCBI chrNW_004936489:13,901,066...14,000,652 JBrowse link
long-chain fatty acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 involved_in ISO (PMID:18757502)
(PMID:23671276)
UniProt PMID:18757502 PMID:23671276 NCBI chrNW_004936809:615,133...634,618 JBrowse link
G Acadl acyl-CoA dehydrogenase long chain ISO RGD PMID:3968063 RGD:2317678 NCBI chrNW_004936845:66,674...96,248 JBrowse link
G Aig1 androgen induced 1 involved_in ISO (PMID:27018888) UniProt PMID:27018888 NCBI chrNW_004936625:2,790,215...3,028,135 JBrowse link
G Lipe lipase E, hormone sensitive type acts_upstream_of_or_within ISO (MGI:3654969|PMID:16804080) MGI PMID:16804080 MGI:3654969 NCBI chrNW_004936706:122,939...139,506 JBrowse link
G LOC101965444 androgen dependent TFPI regulating protein involved_in ISO (PMID:27018888) UniProt PMID:27018888 NCBI chrNW_004936534:1,332,682...1,389,242 JBrowse link
omega-hydroxylase P450 pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101973126 cytochrome P450 2U1 involved_in ISO (PMID:24563460) UniProt PMID:24563460 NCBI chrNW_004936818:650,593...672,349 JBrowse link
palmitic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot7 acyl-CoA thioesterase 7 involved_in ISO (PMID:10578051) BHF-UCL PMID:10578051 NCBI chrNW_004936623:1,112,021...1,191,190 JBrowse link
phytanic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd3 ATP binding cassette subfamily D member 3 involved_in ISO (MGI:5613029|PMID:25168382) UniProt PMID:25168382 MGI:5613029 NCBI chrNW_004936537:4,659,685...4,745,992 JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 involved_in ISO (PMID:28289220) UniProt PMID:28289220 NCBI chrNW_004936473:2,823,183...2,856,077 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12170
    metabolic process 7647
      cellular metabolic process 7012
        cellular lipid metabolic process 721
          fatty acid metabolic process 269
            long-chain fatty acid metabolic process 56
              alpha-linolenic acid metabolic process 0
              arachidonic acid metabolic process + 23
              hepoxilin metabolic process + 5
              linoleic acid metabolic process 7
              long-chain fatty acid biosynthetic process + 14
              long-chain fatty acid catabolic process + 5
              palmitic acid metabolic process + 1
              phytanic acid metabolic process 2
Path 2
Term Annotations click to browse term
  biological_process 12170
    metabolic process 7647
      cellular metabolic process 7012
        organic acid metabolic process 651
          oxoacid metabolic process 633
            carboxylic acid metabolic process 625
              monocarboxylic acid metabolic process 415
                fatty acid metabolic process 269
                  long-chain fatty acid metabolic process 56
                    alpha-linolenic acid metabolic process 0
                    arachidonic acid metabolic process + 23
                    hepoxilin metabolic process + 5
                    linoleic acid metabolic process 7
                    long-chain fatty acid biosynthetic process + 14
                    long-chain fatty acid catabolic process + 5
                    palmitic acid metabolic process + 1
                    phytanic acid metabolic process 2
paths to the root