ONTOLOGY REPORT - ANNOTATIONS
Term: long-chain fatty acid metabolic process
Accession: GO:0001676
browse the term
Definition: The chemical reactions and pathways involving a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
Synonyms: exact_synonym: long-chain fatty acid metabolism
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Acad9
acyl-CoA dehydrogenase family member 9
involved_in
ISO
(PMID:16020546)
BHF-UCL
PMID:16020546
NCBI chrNW_004624781:7,683,025...7,717,427
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Acot9
acyl-CoA thioesterase 9
involved_in
ISO
(MGI:6718236|PMID:23864032)
UniProt
PMID:23864032
MGI:6718236
NCBI chrNW_004624897:125,348...155,557
Ensembl chrNW_004624897:125,348...155,621
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Acsbg1
acyl-CoA synthetase bubblegum family member 1
involved_in
IEA
GOC
GO_REF:0000108
NCBI chrNW_004624894:2,618,000...2,661,174
Ensembl chrNW_004624894:2,617,711...2,661,174
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Acsl1
acyl-CoA synthetase long chain family member 1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624769:15,503,757...15,584,741
Ensembl chrNW_004624769:15,503,757...15,584,777
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Acsl3
acyl-CoA synthetase long chain family member 3
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624823:2,323,939...2,387,213
Ensembl chrNW_004624823:2,324,345...2,381,420
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Acsl4
acyl-CoA synthetase long chain family member 4
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624803:6,272,954...6,372,815
Ensembl chrNW_004624803:6,336,964...6,372,815
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Acsl5
acyl-CoA synthetase long chain family member 5
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624737:34,038,610...34,091,579
Ensembl chrNW_004624737:34,038,518...34,091,661
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Acsl6
acyl-CoA synthetase long chain family member 6
involved_in
ISO IEA
RGD TreeGrafter
PMID:1569043
GO_REF:0000118 RGD:69376
NCBI chrNW_004624733:40,105,795...40,157,108
Ensembl chrNW_004624733:40,105,806...40,160,221
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Cd36
CD36 molecule (CD36 blood group)
ISO
RGD
PMID:15161924
RGD:1598388
NCBI chrNW_004624739:29,341,620...29,441,232
Ensembl chrNW_004624739:29,407,568...29,441,333
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Cpt1a
carnitine palmitoyltransferase 1A
involved_in
ISO
PMID:21990363 (PMID:11350182)
UniProt RGD
PMID:11350182 PMID:19302064 PMID:21990363
RGD:2311346 RGD:8554544
NCBI chrNW_004624767:18,109,011...18,161,378
Ensembl chrNW_004624767:18,109,008...18,161,639
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Cpt2
carnitine palmitoyltransferase 2
involved_in
ISO
(PMID:20538056)
UniProt
PMID:20538056
NCBI chrNW_004624934:1,239,849...1,271,993
Ensembl chrNW_004624934:1,250,956...1,271,983
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LOC101707509
cytochrome P450 1A1
involved_in
ISO
(PMID:18577768)
UniProt
PMID:18577768
NCBI chrNW_004627988:7...1,323
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LOC101722366
cytochrome P450 2E1
involved_in
ISO
(PMID:18577768)
UniProt
PMID:18577768
NCBI chrNW_004624737:12,335,733...12,345,278
Ensembl chrNW_004624737:12,335,681...12,345,514
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Pam
peptidylglycine alpha-amidating monooxygenase
ISO
N-myristoylglycine
RGD
PMID:8660675
RGD:6483540
NCBI chrNW_004624743:20,834,664...21,178,933
Ensembl chrNW_004624743:20,988,916...21,178,933
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Slc27a2
solute carrier family 27 member 2
involved_in acts_upstream_of_or_within
ISO
PMID:10640429 (PMID:12048192) (PMID:22022213)
UniProt MGI
PMID:10640429 PMID:12048192 PMID:22022213
RGD:8554430
NCBI chrNW_004624731:9,862,948...9,896,064
Ensembl chrNW_004624731:9,862,731...9,896,661
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Slc27a3
solute carrier family 27 member 3
involved_in
ISO
(PMID:23936004)
UniProt
PMID:23936004
NCBI chrNW_004624885:3,398,652...3,403,376
Ensembl chrNW_004624885:3,395,839...3,402,542
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Slc27a4
solute carrier family 27 member 4
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:11404000), (PMID:15653672)
GOC MGI
PMID:11404000 PMID:15653672
GO_REF:0000108
NCBI chrNW_004624760:6,529,028...6,542,067
Ensembl chrNW_004624760:6,529,027...6,542,149
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Slc27a5
solute carrier family 27 member 5
involved_in
IEA
GOC
GO_REF:0000108
NCBI chrNW_004624832:84,456...92,706
Ensembl chrNW_004624832:84,552...92,556
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Slc27a6
solute carrier family 27 member 6
involved_in
IEA
GOC
GO_REF:0000108
NCBI chrNW_004624774:12,287,576...12,344,604
Ensembl chrNW_004624774:12,287,918...12,344,375
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Alox12
arachidonate 12-lipoxygenase, 12S type
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624786:9,542,966...9,555,235
Ensembl chrNW_004624786:9,542,970...9,555,214
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Alox12b
arachidonate 12-lipoxygenase, 12R type
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624786:10,647,450...10,659,301
Ensembl chrNW_004624786:10,647,175...10,659,337
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Alox5
arachidonate 5-lipoxygenase
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624966:168,244...220,430
Ensembl chrNW_004624966:168,250...220,522
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Aloxe3
arachidonate epidermal lipoxygenase 3
involved_in
ISO
PMID:23382512 (MGI:3694035|PMID:17045234) (PMID:12881489), (PMID:17045234)
UniProt
PMID:12881489 PMID:17045234 PMID:23382512
MGI:3694035 RGD:8554649
NCBI chrNW_004624786:10,666,255...10,689,204
Ensembl chrNW_004624786:10,666,423...10,688,376
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Dagla
diacylglycerol lipase alpha
involved_in acts_upstream_of
IEA ISO
(PMID:20147530)
TreeGrafter MGI Ensembl
PMID:20147530
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624926:638,432...680,726
Ensembl chrNW_004624926:638,259...656,953
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Daglb
diacylglycerol lipase beta
acts_upstream_of involved_in
ISO IEA
(PMID:20147530)
MGI TreeGrafter
PMID:20147530
GO_REF:0000118
NCBI chrNW_004624740:30,880,252...30,912,257
Ensembl chrNW_004624740:30,880,253...30,909,448
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Ephx1
epoxide hydrolase 1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624835:6,161,930...6,181,016
Ensembl chrNW_004624835:6,162,111...6,168,714
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Fads1
fatty acid desaturase 1
ISO
RGD
PMID:11414679
RGD:632758
NCBI chrNW_004624926:594,421...607,654
Ensembl chrNW_004624926:598,922...606,611
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Gpx1
glutathione peroxidase 1
involved_in
ISO
(MGI:893248|PMID:9195979) (PMID:11115402)
UniProt
PMID:9195979 PMID:11115402
MGI:893248
NCBI chrNW_004624730:3,313,773...3,314,870
Ensembl chrNW_004624730:3,313,972...3,314,626
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Gpx4
glutathione peroxidase 4
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624828:7,534,251...7,536,675
Ensembl chrNW_004624828:7,534,449...7,536,586
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LOC101697745
leukotriene-B4 omega-hydroxylase 3-like
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624901:2,696,827...2,708,803
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LOC101701066
cytochrome P450 1B1
involved_in
ISO
(MGI:5572883|PMID:15258110) (PMID:15258110)
UniProt
PMID:15258110
MGI:5572883
NCBI chrNW_004624738:19,639,215...19,647,807
Ensembl chrNW_004624738:19,638,456...19,647,497
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LOC101708592
cytochrome P450 2C55
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624737:6,040,817...6,100,509
Ensembl chrNW_004624737:6,040,202...6,102,086
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LOC101722985
cytochrome P450 2D6-like
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624752:6,555,442...6,559,294
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LOC101723802
cytochrome P450 2D17-like
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624752:6,585,381...6,594,437
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LOC101724171
cytochrome P450 2D16
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624752:6,567,617...6,577,447
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Mapk3
mitogen-activated protein kinase 3
ISO
RGD
PMID:15027896
RGD:1626220
NCBI chrNW_004624782:13,150,824...13,158,327
Ensembl chrNW_004624782:13,152,039...13,159,113
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Mgll
monoglyceride lipase
involved_in
ISO
(MGI:4836780|PMID:20729846)
UniProt
PMID:20729846
MGI:4836780
NCBI chrNW_004624974:85,513...169,904
Ensembl chrNW_004624974:87,600...170,228
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Pla2g2f
phospholipase A2 group IIF
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624764:5,243,507...5,249,842
Ensembl chrNW_004624764:5,244,152...5,249,842
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Pla2g4a
phospholipase A2 group IVA
involved_in
ISO
(PMID:7794891)
RGD UniProt
PMID:7794891 PMID:16603549
RGD:1642459
NCBI chrNW_004624814:6,597,248...6,744,294
Ensembl chrNW_004624814:6,597,005...6,744,286
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Pnpla8
patatin like phospholipase domain containing 8
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624739:21,252,812...21,305,118
Ensembl chrNW_004624739:21,260,117...21,289,195
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Bdkrb1
bradykinin receptor B1
involved_in
ISO
(PMID:23846981)
AgBase
PMID:23846981
NCBI chrNW_004624734:8,545,707...8,549,846
Ensembl chrNW_004624734:8,548,356...8,549,414
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LOC101701770
protein SCO1 homolog, mitochondrial
acts_upstream_of_or_within
ISO
(PMID:28973536)
MGI
PMID:28973536
NCBI chrNW_004624786:13,038,384...13,053,250
Ensembl chrNW_004624786:13,036,426...13,053,210
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Ptgs1
prostaglandin-endoperoxide synthase 1
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624760:12,917,244...12,937,858
Ensembl chrNW_004624760:12,915,206...12,937,824
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Ptgs2
prostaglandin-endoperoxide synthase 2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:1419907)
TreeGrafter MGI Ensembl
PMID:1419907
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624814:6,897,818...6,904,890
Ensembl chrNW_004624814:6,897,857...6,903,728
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Sphk1
sphingosine kinase 1
ISO
RGD
PMID:18723875
RGD:2311353
NCBI chrNW_004624801:6,253,219...6,257,128
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LOC101700677
cytochrome P450 2S1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624907:57,749...67,274
Ensembl chrNW_004624907:57,276...67,275
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LOC101706775
cytochrome P450 2A3
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624925:821,976...828,733
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LOC101707867
cytochrome P450 2A3
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624925:845,941...852,669
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LOC101708686
cytochrome P450 2A3
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624925:899,729...908,122
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LOC101710356
cytochrome P450 2G1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624925:916,766...929,507
G
LOC101712634
cytochrome P450 2B4
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624925:1,117,935...1,144,465
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LOC101713256
cytochrome P450 2B4
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624925:966,806...994,941
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LOC101722366
cytochrome P450 2E1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624737:12,335,733...12,345,278
Ensembl chrNW_004624737:12,335,681...12,345,514
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Alox12
arachidonate 12-lipoxygenase, 12S type
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624786:9,542,966...9,555,235
Ensembl chrNW_004624786:9,542,970...9,555,214
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Alox12b
arachidonate 12-lipoxygenase, 12R type
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624786:10,647,450...10,659,301
Ensembl chrNW_004624786:10,647,175...10,659,337
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Alox5
arachidonate 5-lipoxygenase
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624966:168,244...220,430
Ensembl chrNW_004624966:168,250...220,522
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Aloxe3
arachidonate epidermal lipoxygenase 3
involved_in
ISO
(MGI:5488571|PMID:22832496) (MGI:3694035|PMID:17045234) (PMID:12881489), (PMID:17045234) PMID:23382512
UniProt
PMID:12881489 PMID:17045234 PMID:22832496 PMID:23382512
MGI:3694035 MGI:5488571 RGD:8554649
NCBI chrNW_004624786:10,666,255...10,689,204
Ensembl chrNW_004624786:10,666,423...10,688,376
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LOC101696396
glutathione S-transferase P
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624767:18,958,447...18,961,679
Ensembl chrNW_004624767:18,957,035...18,961,808
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Alox5
arachidonate 5-lipoxygenase
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624966:168,244...220,430
Ensembl chrNW_004624966:168,250...220,522
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Alox12
arachidonate 12-lipoxygenase, 12S type
NOT|involved_in
ISO
(PMID:1851637) (PMID:8250832)
UniProt
PMID:1851637 PMID:8250832
NCBI chrNW_004624786:9,542,966...9,555,235
Ensembl chrNW_004624786:9,542,970...9,555,214
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LOC101697745
leukotriene-B4 omega-hydroxylase 3-like
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624901:2,696,827...2,708,803
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Ptgr1
prostaglandin reductase 1
involved_in
ISO
(PMID:8394361)
UniProt RGD
PMID:8394361 PMID:9667737
RGD:401959219
NCBI chrNW_004624760:23,406,085...23,433,283
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Alox12
arachidonate 12-lipoxygenase, 12S type
involved_in NOT|involved_in
IEA ISO
(PMID:1851637)
TreeGrafter UniProt
PMID:1851637
GO_REF:0000118
NCBI chrNW_004624786:9,542,966...9,555,235
Ensembl chrNW_004624786:9,542,970...9,555,214
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Alox12b
arachidonate 12-lipoxygenase, 12R type
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624786:10,647,450...10,659,301
Ensembl chrNW_004624786:10,647,175...10,659,337
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Alox5
arachidonate 5-lipoxygenase
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624966:168,244...220,430
Ensembl chrNW_004624966:168,250...220,522
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Aloxe3
arachidonate epidermal lipoxygenase 3
involved_in
ISO
(PMID:12881489), (PMID:17045234) (MGI:3694035|PMID:17045234)
UniProt
PMID:12881489 PMID:17045234
MGI:3694035
NCBI chrNW_004624786:10,666,255...10,689,204
Ensembl chrNW_004624786:10,666,423...10,688,376
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Ephx2
epoxide hydrolase 2
ISO
RGD
PMID:16962614
RGD:5688387
NCBI chrNW_004624758:22,216,462...22,252,467
Ensembl chrNW_004624758:22,221,314...22,254,813
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LOC101696396
glutathione S-transferase P
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624767:18,958,447...18,961,679
Ensembl chrNW_004624767:18,957,035...18,961,808
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LOC101708592
cytochrome P450 2C55
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624737:6,040,817...6,100,509
Ensembl chrNW_004624737:6,040,202...6,102,086
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Pnpla8
patatin like phospholipase domain containing 8
involved_in
ISO
(PMID:15695510)
UniProt
PMID:15695510
NCBI chrNW_004624739:21,252,812...21,305,118
Ensembl chrNW_004624739:21,260,117...21,289,195
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Alox12
arachidonate 12-lipoxygenase, 12S type
involved_in
ISO
(PMID:8250832)
UniProt
PMID:8250832
NCBI chrNW_004624786:9,542,966...9,555,235
Ensembl chrNW_004624786:9,542,970...9,555,214
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Ptgr1
prostaglandin reductase 1
involved_in
ISO
(PMID:11688989)
UniProt
PMID:11688989
NCBI chrNW_004624760:23,406,085...23,433,283
G
Alox12
arachidonate 12-lipoxygenase, 12S type
involved_in
ISO
(PMID:8250832)
UniProt
PMID:8250832
NCBI chrNW_004624786:9,542,966...9,555,235
Ensembl chrNW_004624786:9,542,970...9,555,214
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Acsbg1
acyl-CoA synthetase bubblegum family member 1
ISO
RGD
PMID:11381125
RGD:68727
NCBI chrNW_004624894:2,618,000...2,661,174
Ensembl chrNW_004624894:2,617,711...2,661,174
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Asah2
N-acylsphingosine amidohydrolase 2
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624791:12,906,908...13,059,033
Ensembl chrNW_004624791:12,907,485...13,059,005
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Elovl6
ELOVL fatty acid elongase 6
involved_in
ISO
(PMID:20937905)
UniProt
PMID:20937905
NCBI chrNW_004624838:4,469,321...4,593,919
Ensembl chrNW_004624838:4,468,192...4,593,556
G
Fads1
fatty acid desaturase 1
acts_upstream_of_or_within
ISO
(PMID:10601301)
MGI
PMID:10601301
NCBI chrNW_004624926:594,421...607,654
Ensembl chrNW_004624926:598,922...606,611
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Ltc4s
leukotriene C4 synthase
involved_in
ISO
(PMID:27791009)
UniProt
PMID:27791009
NCBI chrNW_004624733:42,668,963...42,673,385
Ensembl chrNW_004624733:42,670,632...42,672,846
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Myo5a
myosin VA
acts_upstream_of_or_within
ISO
(PMID:1150661)
MGI
PMID:1150661
NCBI chrNW_004624731:8,114,557...8,280,586
Ensembl chrNW_004624731:8,113,715...8,280,823
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Plp1
proteolipid protein 1
acts_upstream_of_or_within
ISO
(PMID:1150661)
MGI
PMID:1150661
NCBI chrNW_004624954:135,065...150,911
Ensembl chrNW_004624954:133,105...150,953
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Qki
QKI, KH domain containing RNA binding
acts_upstream_of_or_within
ISO
(PMID:1150661)
MGI
PMID:1150661
NCBI chrNW_004624785:15,738,231...15,845,051
Ensembl chrNW_004624785:15,739,187...15,845,024
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Abcd1
ATP binding cassette subfamily D member 1
involved_in
ISO
(PMID:23671276) (PMID:18757502)
UniProt
PMID:18757502 PMID:23671276
NCBI chrNW_004624946:421,113...439,961
Ensembl chrNW_004624946:421,132...440,075
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Acadl
acyl-CoA dehydrogenase long chain
involved_in
ISO IEA
RGD InterPro
PMID:3968063
GO_REF:0000002 RGD:2317678
NCBI chrNW_004624765:6,018,534...6,050,736
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Adtrp
androgen dependent TFPI regulating protein
involved_in
ISO
(PMID:27018888)
UniProt
PMID:27018888
NCBI chrNW_004624756:14,289,144...14,354,999
Ensembl chrNW_004624756:14,290,028...14,354,284
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Aig1
androgen induced 1
involved_in
ISO
(PMID:27018888)
UniProt
PMID:27018888
NCBI chrNW_004624753:10,917,856...11,175,696
Ensembl chrNW_004624753:10,914,540...11,175,768
G
Lipe
lipase E, hormone sensitive type
acts_upstream_of_or_within
ISO
(PMID:16804080)
MGI
PMID:16804080
NCBI chrNW_004624907:360,462...379,266
Ensembl chrNW_004624907:363,572...379,194
G
Ahr
aryl hydrocarbon receptor
ISO
RGD
PMID:19889059
RGD:401794453
NCBI chrNW_004624739:12,939,183...12,987,574
Ensembl chrNW_004624739:12,942,165...12,987,973
G
LOC101708291
cytochrome P450 2U1
involved_in
ISO
(PMID:24563460)
UniProt
PMID:24563460
NCBI chrNW_004624830:1,470,186...1,485,804
Ensembl chrNW_004624830:1,469,868...1,485,804
G
Acot7
acyl-CoA thioesterase 7
involved_in
ISO
(PMID:10578051)
BHF-UCL
PMID:10578051
NCBI chrNW_004624818:5,048,410...5,142,135
Ensembl chrNW_004624818:5,065,995...5,142,558
G
Abcd3
ATP binding cassette subfamily D member 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624742:3,146,000...3,236,473
Ensembl chrNW_004624742:3,142,570...3,236,728
G
Hacl1
2-hydroxyacyl-CoA lyase 1
involved_in
ISO
(PMID:28289220)
UniProt
PMID:28289220
NCBI chrNW_004624822:5,078,925...5,189,253
Ensembl chrNW_004624822:5,079,634...5,145,503
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all