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ONTOLOGY REPORT - ANNOTATIONS


Term:cholesterol 25-hydroxylase activity
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Accession:GO:0001567 term browser browse the term
Definition:Catalysis of the reaction: AH2 + cholesterol + O2 = 25-hydroxycholesterol + A + H2O.
Synonyms:related_synonym: cholesterol 25-monooxygenase activity;   cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating) activity
 xref: EC:1.14.99.38;   KEGG_REACTION:R07218;   MetaCyc:1.14.99.38-RXN;   RHEA:21104



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cholesterol 25-hydroxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase enables ISS
ISO
GO_REF:0000024
(PMID:32944968)
(PMID:22999953), (PMID:29033131)
UniProt
RGD
PMID:22999953 PMID:29033131 PMID:32944968 GO_REF:0000024 NCBI chr 1:241,428,048...241,429,366
Ensembl chr 1:232,014,880...232,016,195
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Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      oxidoreductase activity 869
        oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 244
          cholesterol 25-hydroxylase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      oxidoreductase activity 869
        monooxygenase activity 165
          steroid hydroxylase activity 36
            cholesterol 25-hydroxylase activity 1
paths to the root