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ONTOLOGY REPORT - ANNOTATIONS

Term:fatty acid alpha-oxidation
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Accession:GO:0001561 term browser browse the term
Definition:A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.
Synonyms:xref: MetaCyc:PWY-2501

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fatty acid alpha-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hacl1 2-hydroxyacyl-CoA lyase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936473:2,823,183...2,856,077
Ensembl chrNW_004936473:2,823,123...2,856,077 		JBrowse link
G Hao1 hydroxyacid oxidase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936485:11,435,151...11,486,042
Ensembl chrNW_004936485:11,435,151...11,486,042 		JBrowse link
G Hao2 hydroxyacid oxidase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936627:4,167,501...4,179,596
Ensembl chrNW_004936627:4,159,214...4,179,806 		JBrowse link
G Ilvbl ilvB acetolactate synthase like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:5,343,895...5,352,804
Ensembl chrNW_004936596:5,343,761...5,354,264 		JBrowse link
G LOC101958596 phytanoyl-CoA dioxygenase, peroxisomal-like involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936613:75,222...88,765 JBrowse link
G Pex13 peroxisomal biogenesis factor 13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12897163) Ensembl
MGI		 PMID:12897163 GO_REF:0000107 NCBI chrNW_004936491:6,530,385...6,559,706
Ensembl chrNW_004936491:6,529,779...6,562,590 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:12,259,779...12,298,760
Ensembl chrNW_004936471:12,259,734...12,298,760 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16121
    cellular process 15174
      cellular metabolic process 8541
        cellular lipid metabolic process 937
          fatty acid metabolic process 379
            fatty acid oxidation 111
              fatty acid alpha-oxidation 7
Path 2
Term Annotations click to browse term
  biological_process 16121
    metabolic process 10242
      cellular metabolic process 8541
        organic acid metabolic process 890
          oxoacid metabolic process 873
            carboxylic acid metabolic process 862
              monocarboxylic acid metabolic process 595
                fatty acid metabolic process 379
                  fatty acid catabolic process 100
                    fatty acid alpha-oxidation 7
paths to the root