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ONTOLOGY REPORT - ANNOTATIONS

Term:fatty acid alpha-oxidation
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Accession:GO:0001561 term browser browse the term
Definition:A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.
Synonyms:xref: MetaCyc:PWY-2501

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fatty acid alpha-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hacl1 2-hydroxyacyl-CoA lyase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624822:5,078,925...5,189,253
Ensembl chrNW_004624822:5,079,634...5,145,503 		JBrowse link
G Hao1 hydroxyacid oxidase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624741:8,762,556...8,824,517
Ensembl chrNW_004624741:8,763,496...8,824,468 		JBrowse link
G Hao2 hydroxyacid oxidase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624772:14,981,777...15,022,699
Ensembl chrNW_004624772:14,981,666...15,023,173 		JBrowse link
G Ilvbl ilvB acetolactate synthase like involved_in ISO (PMID:28289220) UniProt PMID:28289220 NCBI chrNW_004624901:2,198,000...2,207,849
Ensembl chrNW_004624901:2,198,272...2,206,545 		JBrowse link
G Pex13 peroxisomal biogenesis factor 13 acts_upstream_of_or_within ISO (PMID:12897163) MGI PMID:12897163 NCBI chrNW_004624833:914,621...940,661
Ensembl chrNW_004624833:913,337...940,611 		JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:12915479), (PMID:9326939) RGD
InterPro
MGI
TreeGrafter		 PMID:9326939 PMID:10588950 PMID:12915479 GO_REF:0000002 GO_REF:0000118 RGD:727286 NCBI chrNW_004624805:5,801,392...5,813,696 JBrowse link
G Slc27a2 solute carrier family 27 member 2 involved_in ISO (PMID:10198260) UniProt PMID:10198260 NCBI chrNW_004624731:9,862,948...9,896,064
Ensembl chrNW_004624731:9,862,731...9,896,661 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15225
    cellular process 14346
      cellular metabolic process 8101
        cellular lipid metabolic process 880
          fatty acid metabolic process 342
            fatty acid oxidation 104
              fatty acid alpha-oxidation 7
Path 2
Term Annotations click to browse term
  biological_process 15225
    metabolic process 9679
      cellular metabolic process 8101
        organic acid metabolic process 812
          oxoacid metabolic process 804
            carboxylic acid metabolic process 792
              monocarboxylic acid metabolic process 541
                fatty acid metabolic process 342
                  fatty acid catabolic process 96
                    fatty acid alpha-oxidation 7
paths to the root