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ONTOLOGY REPORT - ANNOTATIONS


Term:oocyte maturation
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Accession:GO:0001556 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
Synonyms:xref: Wikipedia:Oocyte_maturation
 only_in_taxon: NCBITaxon:33208 ! Metazoa



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oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANG angiogenin involved_in NAS (PMID:11438326) UniProt PMID:11438326 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971
JBrowse link
G BRCA2 BRCA2 DNA repair associated acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2683946|PMID:14660434) MGI
Ensembl
PMID:14660434 GO_REF:0000107 MGI:2683946 NCBI chr13:32,315,508...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
G CCNB1 cyclin B1 ISO RGD PMID:15291744 RGD:1578405 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
JBrowse link
G CDC25B cell division cycle 25B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2682954|PMID:11912493) MGI
Ensembl
PMID:11912493 GO_REF:0000107 MGI:2682954 NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,121
JBrowse link
G DAZL deleted in azoospermia like acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4946299|PMID:21460039) MGI
Ensembl
PMID:21460039 GO_REF:0000107 MGI:4946299 NCBI chr 3:16,586,792...16,605,423
Ensembl chr 3:16,586,792...16,670,306
JBrowse link
G DMC1 DNA meiotic recombinase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3719060|PMID:17696610) MGI
Ensembl
PMID:17696610 GO_REF:0000107 MGI:3719060 NCBI chr22:38,509,147...38,570,183
Ensembl chr22:38,518,948...38,570,204
JBrowse link
G EREG epiregulin involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749
JBrowse link
G FBXO5 F-box protein 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3521521|PMID:15526037) MGI
Ensembl
PMID:15526037 GO_REF:0000107 MGI:3521521 NCBI chr 6:152,970,535...152,983,579
Ensembl chr 6:152,970,519...152,983,579
JBrowse link
G FOXO3 forkhead box O3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2667256|PMID:12855809) MGI
Ensembl
PMID:12855809 GO_REF:0000107 MGI:2667256 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G H3-3A H3.3 histone A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:226,061,831...226,072,019
Ensembl chr 1:226,061,851...226,072,019
JBrowse link
G H3-3B H3.3 histone B involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:75,776,434...75,779,779
Ensembl chr17:75,776,434...75,785,893
JBrowse link
G INSL3 insulin like 3 involved_in ISO
IEA
in preovulatory follicles RGD
Ensembl
PMID:15123806 GO_REF:0000107 RGD:1600181 NCBI chr19:17,816,512...17,821,519
Ensembl chr19:17,816,512...17,821,574
JBrowse link
G MOS MOS proto-oncogene, serine/threonine kinase involved_in IMP (PMID:34779126), (PMID:34997960), (PMID:35670744) UniProt PMID:34779126 PMID:34997960 PMID:35670744 NCBI chr 8:56,112,942...56,113,982
Ensembl chr 8:56,112,942...56,113,982
JBrowse link
G OOSP2 oocyte secreted protein 2 involved_in IMP (PMID:36042231) UniProt PMID:36042231 NCBI chr11:60,040,409...60,048,044
Ensembl chr11:60,040,409...60,048,044
JBrowse link
G PABPC1L poly(A) binding protein cytoplasmic 1 like acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5688228|PMID:26134869)
(MGI:5437387|PMID:22621333)
MGI
Ensembl
PMID:22621333 PMID:26134869 GO_REF:0000107 MGI:5437387 MGI:5688228 NCBI chr20:44,910,060...44,939,316
Ensembl chr20:44,910,060...44,959,035
JBrowse link
G PDE3A phosphodiesterase 3A involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:2136575|PMID:11420239) RGD
TreeGrafter
Ensembl
MGI
PMID:11420239 PMID:11673261 GO_REF:0000107 GO_REF:0000118 MGI:2136575 RGD:731220 NCBI chr12:20,368,537...20,688,583
Ensembl chr12:20,368,537...20,688,583
JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in ISO
IEA
RGD
Ensembl
PMID:17127746 GO_REF:0000107 RGD:1642612 NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391
JBrowse link
G REC8 REC8 meiotic recombination protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3719060|PMID:17696610) MGI
Ensembl
PMID:17696610 GO_REF:0000107 MGI:3719060 NCBI chr14:24,172,080...24,180,923
Ensembl chr14:24,171,853...24,180,257
JBrowse link
G RLN2 relaxin 2 involved_in ISO (PMID:21272344) CACAO PMID:21272344 NCBI chr 9:5,299,864...5,339,326
Ensembl chr 9:5,299,864...5,304,716
JBrowse link
G RPS6KA2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (MGI:3521521|PMID:15526037) MGI PMID:15526037 MGI:3521521 NCBI chr 6:166,409,364...166,862,773
Ensembl chr 6:166,409,364...166,906,451
JBrowse link
G RXFP2 relaxin family peptide receptor 2 involved_in ISO
IEA
in preovulatory follicles RGD
Ensembl
PMID:15123806 GO_REF:0000107 RGD:1600181 NCBI chr13:31,739,526...31,803,389
Ensembl chr13:31,739,526...31,803,389
JBrowse link
G TRIP13 thyroid hormone receptor interactor 13 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3719060|PMID:17696610) MGI
Ensembl
PMID:17696610 GO_REF:0000107 MGI:3719060 NCBI chr 5:892,884...919,348
Ensembl chr 5:892,884...919,357
JBrowse link
G TUBB8 tubulin beta 8 class VIII involved_in IMP (PMID:26789871) UniProt PMID:26789871 NCBI chr10:46,455...76,621
Ensembl chr10:46,888...74,163
JBrowse link
G TUT4 terminal uridylyl transferase 4 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:52,423,275...52,553,463
Ensembl chr 1:52,408,282...52,553,487
JBrowse link
G TUT7 terminal uridylyl transferase 7 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:86,287,733...86,354,410
Ensembl chr 9:86,287,733...86,354,454
JBrowse link
G WASHC1 WASH complex subunit 1 involved_in ISO (MGI:5613746|PMID:24998208) UniProt PMID:24998208 MGI:5613746 NCBI chr 9:14,513...30,487
Ensembl chr 9:14,475...73,865
JBrowse link
G WASHC5 WASH complex subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:125,024,260...125,091,792
Ensembl chr 8:125,024,260...125,091,819
JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein F2 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:28,736,624...28,769,775
Ensembl chr 1:28,736,621...28,769,775
JBrowse link
G ZAR1 zygote arrest 1 involved_in ISS (PMID:31598710), (PMID:36264786) UniProt PMID:31598710 PMID:36264786 GO_REF:0000024 NCBI chr 4:48,490,252...48,497,635
Ensembl chr 4:48,490,252...48,494,389
JBrowse link
G ZAR1L zygote arrest 1 like involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr13:32,303,699...32,315,363
Ensembl chr13:32,303,699...32,315,363
JBrowse link
meiotic cell cycle process involved in oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK1 cyclin dependent kinase 1 involved_in ISO (PMID:19550110), (PMID:24374180) AgBase PMID:19550110 PMID:24374180 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
JBrowse link
G EDN1 endothelin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EDNRA endothelin receptor type A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
JBrowse link
G NPPC natriuretic peptide C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:231,921,809...231,926,396
Ensembl chr 2:231,921,809...231,926,396
JBrowse link
G NPR2 natriuretic peptide receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:35,791,591...35,809,731
Ensembl chr 9:35,791,003...35,809,732
JBrowse link
negative regulation of meiotic cell cycle process involved in oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNB1 cyclin B1 involved_in ISO (PMID:12954723) AgBase PMID:12954723 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
JBrowse link
G CCNB2 cyclin B2 involved_in ISO (PMID:12954723) AgBase PMID:12954723 NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045
JBrowse link
G FZR1 fizzy and cell division cycle 20 related 1 involved_in ISO (PMID:18753608) AgBase PMID:18753608 NCBI chr19:3,506,311...3,538,334
Ensembl chr19:3,506,311...3,538,334
JBrowse link
G GPR3 G protein-coupled receptor 3 involved_in ISO (PMID:22685609) AgBase PMID:22685609 NCBI chr 1:27,392,622...27,395,814
Ensembl chr 1:27,392,622...27,395,814
JBrowse link
G GRB14 growth factor receptor bound protein 14 involved_in ISO PMID:14623073 CAFA PMID:14623073 RGD:12793049 NCBI chr 2:164,492,417...164,621,482
Ensembl chr 2:164,492,417...164,621,482
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:22674394) AgBase PMID:22674394 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084
JBrowse link
G WEE2 WEE2 oocyte meiosis inhibiting kinase involved_in ISO (PMID:19550110) AgBase PMID:19550110 NCBI chr 7:141,708,353...141,731,271
Ensembl chr 7:141,708,353...141,731,271
JBrowse link
negative regulation of oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR3 G protein-coupled receptor 3 involved_in ISO (PMID:22685609) AgBase PMID:22685609 NCBI chr 1:27,392,622...27,395,814
Ensembl chr 1:27,392,622...27,395,814
JBrowse link
G NPPC natriuretic peptide C acts_upstream_of_or_within
involved_in
IDA
IEA
(PMID:20947764) MGI
Ensembl
PMID:20947764 GO_REF:0000107 NCBI chr 2:231,921,809...231,926,396
Ensembl chr 2:231,921,809...231,926,396
JBrowse link
G NPR2 natriuretic peptide receptor 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4835576|PMID:20947764) MGI
Ensembl
PMID:20947764 GO_REF:0000107 MGI:4835576 NCBI chr 9:35,791,591...35,809,731
Ensembl chr 9:35,791,003...35,809,732
JBrowse link
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4462301|PMID:20585392) MGI
Ensembl
PMID:20585392 GO_REF:0000107 MGI:4462301 NCBI chr 9:37,915,898...38,069,227
Ensembl chr 9:37,915,898...38,069,227
JBrowse link
G WEE2 WEE2 oocyte meiosis inhibiting kinase involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:141,708,353...141,731,271
Ensembl chr 7:141,708,353...141,731,271
JBrowse link
positive regulation of meiotic cell cycle process involved in oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP1 A-kinase anchoring protein 1 involved_in ISO (PMID:23426434) AgBase PMID:23426434 NCBI chr17:57,085,246...57,121,344
Ensembl chr17:57,085,092...57,121,346
JBrowse link
G AURKA aurora kinase A involved_in ISO (PMID:18614302), (PMID:20662813) AgBase PMID:18614302 PMID:20662813 NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337
JBrowse link
G CDC20 cell division cycle 20 involved_in ISO (PMID:18753608) AgBase PMID:18753608 NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203
JBrowse link
G CDK1 cyclin dependent kinase 1 involved_in ISO (PMID:21778139), (PMID:22674394) AgBase PMID:21778139 PMID:22674394 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
JBrowse link
G CDK2 cyclin dependent kinase 2 involved_in ISO (PMID:15750306) AgBase PMID:15750306 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CDK7 cyclin dependent kinase 7 involved_in ISO (PMID:21778139) AgBase PMID:21778139 NCBI chr 5:69,234,795...69,277,430
Ensembl chr 5:69,234,795...69,277,430
JBrowse link
G CPEB1 cytoplasmic polyadenylation element binding protein 1 involved_in ISO (PMID:20662813) AgBase PMID:20662813 NCBI chr15:82,543,201...82,648,795
Ensembl chr15:82,543,201...82,648,861
JBrowse link
G MASTL microtubule associated serine/threonine kinase like involved_in ISO (PMID:23843240) AgBase PMID:23843240 NCBI chr10:27,154,479...27,187,953
Ensembl chr10:27,154,824...27,187,953
JBrowse link
G PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha involved_in ISO (PMID:22674394) AgBase PMID:22674394 NCBI chr 3:48,744,591...48,847,874
Ensembl chr 3:48,744,597...48,847,874
JBrowse link
G SPDYA speedy/RINGO cell cycle regulator family member A involved_in ISO (PMID:17151349) AgBase PMID:17151349 NCBI chr 2:28,810,834...28,850,610
Ensembl chr 2:28,782,517...28,850,611
JBrowse link
positive regulation of oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AURKA aurora kinase A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3045818|PMID:14695913) MGI
Ensembl
PMID:14695913 GO_REF:0000107 MGI:3045818 NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337
JBrowse link
G BNC1 basonuclin zinc finger protein 1 involved_in IMP (PMID:30010909) UniProt PMID:30010909 NCBI chr15:83,255,884...83,284,664
Ensembl chr15:83,255,884...83,284,664
JBrowse link
G GDF9 growth differentiation factor 9 involved_in ISO (PMID:24313324) AgBase PMID:24313324 NCBI chr 5:132,861,185...132,866,651
Ensembl chr 5:132,861,181...132,866,884
JBrowse link
G SIRT2 sirtuin 2 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862
JBrowse link
regulation of meiotic cell cycle process involved in oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP5 A-kinase anchoring protein 5 involved_in ISO (PMID:24501172) AgBase PMID:24501172 NCBI chr14:64,465,499...64,474,503
Ensembl chr14:64,465,499...64,474,503
JBrowse link
G PPP2R1A protein phosphatase 2 scaffold subunit Aalpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5586612|PMID:24899574) MGI
Ensembl
PMID:24899574 GO_REF:0000107 MGI:5586612 NCBI chr19:52,190,052...52,229,518
Ensembl chr19:52,170,936...52,229,518
JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha involved_in ISO (PMID:24501172) AgBase PMID:24501172 NCBI chr17:68,413,623...68,551,316
Ensembl chr17:68,511,780...68,551,319
JBrowse link
G PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha involved_in ISO (PMID:24501172) AgBase PMID:24501172 NCBI chr 3:48,744,591...48,847,874
Ensembl chr 3:48,744,597...48,847,874
JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein F2 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:28,736,624...28,769,775
Ensembl chr 1:28,736,621...28,769,775
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19761
    cellular process 18444
      cellular process involved in reproduction in multicellular organism 612
        oocyte maturation 57
          meiotic cell cycle process involved in oocyte maturation + 25
          negative regulation of oocyte maturation + 10
          positive regulation of oocyte maturation 4
          regulation of oocyte maturation + 14
Path 2
Term Annotations click to browse term
  biological_process 19761
    reproduction 2076
      reproductive process 2037
        multicellular organismal reproductive process 1273
          gamete generation 1073
            germ cell development 474
              oogenesis 142
                oocyte differentiation 92
                  oocyte development 87
                    oocyte maturation 57
                      meiotic cell cycle process involved in oocyte maturation + 25
                      negative regulation of oocyte maturation + 10
                      positive regulation of oocyte maturation 4
                      regulation of oocyte maturation + 14
paths to the root