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ONTOLOGY REPORT - ANNOTATIONS


Term:oocyte maturation
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Accession:GO:0001556 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
Synonyms:xref: Wikipedia:Oocyte_maturation
 only_in_taxon: NCBITaxon:33208 ! Metazoa


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oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2177233 (MGI:2683946|PMID:14660434)
Ensembl
RGD
PMID:14660434 GO_REF:0000107 MGI:2683946 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Ccnb1 cyclin B1 IMP RGD PMID:15291744 RGD:1578405 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cdc25b cell division cycle 25B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2682953 (MGI:2682954|PMID:11912493)
Ensembl
RGD
PMID:11912493 GO_REF:0000107 MGI:2682954 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Dazl deleted in azoospermia-like acts_upstream_of_or_within ISO (MGI:4946299|PMID:21460039) RGD PMID:21460039 MGI:4946299 NCBI chr 9:12,633,983...12,651,017
Ensembl chr 9:12,633,990...12,650,938
JBrowse link
G Dmc1 DNA meiotic recombinase 1 acts_upstream_of_or_within ISO MGI:2176331 (MGI:3719060|PMID:17696610) RGD PMID:17696610 MGI:3719060 NCBI chr 7:120,796,217...120,840,524
Ensembl chr 7:120,796,217...120,839,577
JBrowse link
G Ereg epiregulin involved_in IDA PMID:15459120 UniProt PMID:15459120 RGD:2316284 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Fbxo5 F-box protein 5 acts_upstream_of_or_within ISO (MGI:3521521|PMID:15526037) RGD PMID:15526037 MGI:3521521 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within ISO MGI:2668328 (MGI:2667256|PMID:12855809) RGD PMID:12855809 MGI:2667256 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Insl3 insulin-like 3 IDA in preovulatory follicles RGD PMID:15123806 RGD:1600181 NCBI chr16:20,120,753...20,122,702
Ensembl chr16:20,121,352...20,122,696
JBrowse link
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like acts_upstream_of_or_within ISO MGI:5437740 (MGI:5437387|PMID:22621333), (MGI:5688228|PMID:26134869) RGD PMID:22621333 PMID:26134869 MGI:5437387 MGI:5688228 NCBI chr 3:160,410,733...160,447,073
Ensembl chr 3:160,410,757...160,444,940
JBrowse link
G Pde3a phosphodiesterase 3A acts_upstream_of_or_within
involved_in
TAS
ISO
IBA
IEP
(MGI:2136575|PMID:11420239)
PMID:21873635
RGD PMID:11420239, PMID:11673261, PMID:21873635, PMID:11673261 MGI:2136575, RGD:731220, RGD:13792537, RGD:731220 NCBI chr 4:175,431,904...175,703,844
Ensembl chr 4:175,431,904...175,700,238
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:17127746 RGD:1642612 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Rec8 REC8 meiotic recombination protein acts_upstream_of_or_within ISO MGI:1916966|MGI:3512754 (MGI:3719060|PMID:17696610) RGD PMID:17696610 MGI:3719060 NCBI chr15:34,296,922...34,304,387
Ensembl chr15:34,296,922...34,304,552
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (MGI:3521521|PMID:15526037) RGD PMID:15526037 MGI:3521521 NCBI chr 1:53,219,346...53,499,445
Ensembl chr 1:53,360,157...53,499,445
JBrowse link
G Rxfp2 relaxin family peptide receptor 2 IDA in preovulatory follicles RGD PMID:15123806 RGD:1600181 NCBI chr12:6,016,884...6,078,411
Ensembl chr12:6,016,884...6,078,411
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 acts_upstream_of_or_within ISO MGI:1929645|MGI:3719273 (MGI:3719060|PMID:17696610) RGD PMID:17696610 MGI:3719060 NCBI chr 1:31,967,980...32,012,923
Ensembl chr 1:31,967,978...32,012,919
JBrowse link
G Tut4 terminal uridylyl transferase 4 involved_in ISO (MGI:6162305|PMID:28792939) RGD PMID:28792939 MGI:6162305 NCBI chr 5:128,063,880...128,168,726
Ensembl chr 5:128,083,118...128,168,207
JBrowse link
G Tut7 terminal uridylyl transferase 7 involved_in ISO (MGI:6162305|PMID:28792939) RGD PMID:28792939 MGI:6162305 NCBI chr17:5,225,854...5,279,674
Ensembl chr17:5,225,835...5,271,794
JBrowse link
G Washc1 WASH complex subunit 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5613746|PMID:24998208)
Ensembl
RGD
PMID:24998208 GO_REF:0000107 MGI:5613746 NCBI chr 9:113,918,914...113,936,861
Ensembl chr 9:113,918,858...113,936,860
JBrowse link
G Washc5 WASH complex subunit 5 involved_in ISO (MGI:5613746|PMID:24998208) RGD PMID:24998208 MGI:5613746 NCBI chr 7:99,625,379...99,677,237
Ensembl chr 7:99,625,619...99,677,268
JBrowse link
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 involved_in ISO (MGI:5911735|PMID:28867294) RGD PMID:28867294 MGI:5911735 NCBI chr 5:150,364,490...150,390,173
Ensembl chr 5:150,365,101...150,390,099
JBrowse link
meiotic cell cycle process involved in oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk1 cyclin-dependent kinase 1 involved_in ISO (PMID:19550110), (PMID:24374180) RGD PMID:19550110 PMID:24374180 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Kif20a kinesin family member 20A involved_in ISO (PMID:25036038) RGD PMID:25036038 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
negative regulation of meiotic cell cycle process involved in oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 involved_in ISO (PMID:12954723) RGD PMID:12954723 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 involved_in ISO (PMID:12954723) RGD PMID:12954723 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in ISO (PMID:18753608) RGD PMID:18753608 NCBI chr 7:11,201,690...11,213,614
Ensembl chr 7:11,201,690...11,213,613
JBrowse link
G Gpr3 G protein-coupled receptor 3 involved_in ISO (PMID:22685609) RGD PMID:22685609 NCBI chr 5:151,394,118...151,397,634
Ensembl chr 5:151,394,524...151,397,603
JBrowse link
G Grb14 growth factor receptor bound protein 14 involved_in IMP PMID:14623073 CAFA PMID:14623073 RGD:12793049 NCBI chr 3:50,937,403...51,054,447
Ensembl chr 3:50,937,669...51,054,378
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:22674394) RGD PMID:22674394 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
negative regulation of oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr3 G protein-coupled receptor 3 involved_in ISO (PMID:22685609) RGD PMID:22685609 NCBI chr 5:151,394,118...151,397,634
Ensembl chr 5:151,394,524...151,397,603
JBrowse link
G Nppc natriuretic peptide C involved_in
acts_upstream_of_or_within
ISO (PMID:20947764)
MGI:2388899 (MGI:4835576|PMID:20947764)
RGD PMID:20947764 MGI:4835576 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Npr2 natriuretic peptide receptor 2 acts_upstream_of_or_within ISO MGI:2152891 (MGI:4835576|PMID:20947764) RGD PMID:20947764 MGI:4835576 NCBI chr 5:59,128,186...59,147,321
Ensembl chr 5:59,128,315...59,147,255
JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO MGI:3721903 (MGI:4462301|PMID:20585392) RGD PMID:20585392 MGI:4462301 NCBI chr 5:60,970,650...61,077,881
Ensembl chr 5:60,971,257...61,077,627
JBrowse link
G Wee2 WEE2 oocyte meiosis inhibiting kinase involved_in ISO (MGI:3604224|PMID:16169490), (MGI:4948986|PMID:21454751) RGD PMID:16169490 PMID:21454751 MGI:3604224 MGI:4948986 NCBI chr 4:68,604,770...68,631,341
Ensembl chr 4:68,608,137...68,629,925
JBrowse link
positive regulation of meiotic cell cycle process involved in oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurka aurora kinase A involved_in ISO (PMID:18614302), (PMID:20662813) RGD PMID:18614302 PMID:20662813 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Ccnh cyclin H involved_in ISO (PMID:21778139) RGD PMID:21778139 NCBI chr 2:13,593,100...13,613,910
Ensembl chr 2:13,593,100...13,613,910
JBrowse link
G Cdc20 cell division cycle 20 involved_in ISO (PMID:18753608) RGD PMID:18753608 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdk1 cyclin-dependent kinase 1 involved_in ISO (PMID:21778139), (PMID:22674394) RGD PMID:21778139 PMID:22674394 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 involved_in ISO (PMID:15750306) RGD PMID:15750306 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk7 cyclin-dependent kinase 7 involved_in ISO (PMID:21778139) RGD PMID:21778139 NCBI chr 2:30,710,642...30,735,522
Ensembl chr 2:30,710,643...30,735,514
JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 involved_in ISO (PMID:20662813) RGD PMID:20662813 NCBI chr 1:143,171,457...143,278,485
Ensembl chr 1:143,171,264...143,278,485
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like involved_in ISO (PMID:23843240) RGD PMID:23843240 NCBI chr17:89,839,562...89,875,855
Ensembl chr17:89,742,140...89,876,825
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha involved_in ISO (PMID:22674394) RGD PMID:22674394 NCBI chr 8:117,486,085...117,548,768
Ensembl chr 8:117,486,083...117,546,370
JBrowse link
positive regulation of oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurka aurora kinase A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3045818|PMID:14695913)
Ensembl
RGD
PMID:14695913 GO_REF:0000107 MGI:3045818 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Bnc1 basonuclin 1 involved_in ISO (PMID:30010909) RGD PMID:30010909 NCBI chr 1:143,793,280...143,818,748
NCBI chr 1:143,869,440...143,878,077
Ensembl chr 1:143,793,064...143,818,706
JBrowse link
G Gdf9 growth differentiation factor 9 involved_in ISO (PMID:24313324) RGD PMID:24313324 NCBI chr10:38,782,519...38,793,238
Ensembl chr10:38,788,992...38,792,940
JBrowse link
G Sirt2 sirtuin 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5567889|PMID:24334550)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:24334550 GO_REF:0000024 GO_REF:0000107 MGI:5567889 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
regulation of meiotic cell cycle process involved in oocyte maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap5 A-kinase anchoring protein 5 involved_in ISO (PMID:24501172) RGD PMID:24501172 NCBI chr 6:99,356,509...99,361,909
Ensembl chr 6:99,356,509...99,361,909
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha acts_upstream_of_or_within ISO MGI:5287252 (MGI:5586612|PMID:24899574) RGD PMID:24899574 MGI:5586612 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha involved_in ISO (PMID:24501172) RGD PMID:24501172 NCBI chr10:97,940,705...97,959,199
Ensembl chr10:97,940,705...97,957,336
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha involved_in ISO (PMID:24501172) RGD PMID:24501172 NCBI chr 8:117,486,085...117,548,768
Ensembl chr 8:117,486,083...117,546,370
JBrowse link
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 involved_in ISO (MGI:5911735|PMID:28867294) RGD PMID:28867294 MGI:5911735 NCBI chr 5:150,364,490...150,390,173
Ensembl chr 5:150,365,101...150,390,099
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19633
    cellular process 18481
      cellular process involved in reproduction in multicellular organism 464
        oocyte maturation 46
          meiotic cell cycle process involved in oocyte maturation + 20
          negative regulation of oocyte maturation + 10
          positive regulation of oocyte maturation 4
          regulation of oocyte maturation + 14
Path 2
Term Annotations click to browse term
  biological_process 19633
    reproduction 1798
      reproductive process 1795
        multi-organism reproductive process 1251
          sexual reproduction 997
            gamete generation 821
              female gamete generation 177
                oogenesis 111
                  oocyte differentiation 73
                    oocyte development 68
                      oocyte maturation 46
                        meiotic cell cycle process involved in oocyte maturation + 20
                        negative regulation of oocyte maturation + 10
                        positive regulation of oocyte maturation 4
                        regulation of oocyte maturation + 14
paths to the root