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ONTOLOGY REPORT - ANNOTATIONS


Term:retinoid metabolic process
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Accession:GO:0001523 term browser browse the term
Definition:The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
Synonyms:exact_synonym: retinoid metabolism


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retinoid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide acts_upstream_of_or_within ISO (MGI:2180234|PMID:12027900) MGI PMID:12027900 MGI:2180234 NCBI chrNW_004955496:8,136,279...8,149,496 JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide involved_in ISO (PMID:16787387), (PMID:9600267) UniProt PMID:9600267 PMID:16787387 NCBI chrNW_004955496:8,065,943...8,100,878
Ensembl chrNW_004955496:8,065,943...8,102,066
JBrowse link
G Bco1 beta-carotene oxygenase 1 involved_in ISO (PMID:11401432)
(MGI:1931377|PMID:11092891)
PMID:12468597
UniProt PMID:11092891 PMID:11401432 PMID:12468597 MGI:1931377 RGD:634627 NCBI chrNW_004955522:3,985,515...4,018,116
Ensembl chrNW_004955522:3,985,266...4,018,886
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 acts_upstream_of_or_within ISO (MGI:5528782|PMID:24005908) MGI PMID:24005908 MGI:5528782 NCBI chrNW_004955486:1,439,179...1,473,476
Ensembl chrNW_004955486:1,439,179...1,474,130
JBrowse link
G Rarres2 retinoic acid receptor responder 2 involved_in ISO (PMID:9204961) UniProt PMID:9204961 NCBI chrNW_004955491:4,954,809...4,957,724
Ensembl chrNW_004955491:4,955,068...4,956,956
JBrowse link
G Rdh11 retinol dehydrogenase 11 involved_in ISO (PMID:12226107) UniProt PMID:12226107 NCBI chrNW_004955466:2,506,641...2,521,506
Ensembl chrNW_004955466:2,508,338...2,520,903
JBrowse link
G Rdh5 retinol dehydrogenase 5 involved_in ISO (PMID:9931293)
(MGI:1350674|PMID:10588954)
UniProt PMID:9931293 PMID:10588954 MGI:1350674 NCBI chrNW_004955458:3,356,324...3,361,701
Ensembl chrNW_004955458:3,352,012...3,365,080
JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 involved_in ISO (PMID:16150724)
(PMID:25112876)
UniProt PMID:16150724 PMID:25112876 NCBI chrNW_004955423:23,184,326...23,208,206
Ensembl chrNW_004955423:23,183,937...23,208,282
JBrowse link
9-cis-retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 acts_upstream_of_or_within ISO (MGI:2662611|PMID:11876656) MGI PMID:11876656 MGI:2662611 NCBI chrNW_004955450:16,406,578...16,453,048
Ensembl chrNW_004955450:16,406,436...16,453,180
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family member A1 acts_upstream_of_or_within ISO (MGI:2662611|PMID:11876656) MGI PMID:11876656 MGI:2662611 NCBI chrNW_004955439:1,773,884...1,794,325
Ensembl chrNW_004955439:1,773,861...1,794,328
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in ISO (PMID:11304534) UniProt PMID:11304534 NCBI chrNW_004955449:5,360,486...5,380,279
Ensembl chrNW_004955449:5,359,617...5,380,267
JBrowse link
G LOC102010850 cytochrome P450 1A1 ISO 9-cis- and all-trans-retinoic acid synthesized from 9-cis- and all-trans-retinal RGD PMID:8765131 RGD:2306683 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488
JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt3 protein arginine methyltransferase 3 involved_in ISO (PMID:33495566) UniProt PMID:33495566 NCBI chrNW_004955476:1,222,579...1,331,582
Ensembl chrNW_004955476:1,223,076...1,331,582
JBrowse link
positive regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rdh10 retinol dehydrogenase 10 ISO RGD PMID:21138835 RGD:6771354 NCBI chrNW_004955444:6,878,722...6,909,421
Ensembl chrNW_004955444:6,878,722...6,909,421
JBrowse link
regulation of vitamin A metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgat1 diacylglycerol O-acyltransferase 1 ISO RGD PMID:18000880 RGD:10400849 NCBI chrNW_004955454:2,933,904...2,944,675
Ensembl chrNW_004955454:2,934,152...2,944,492
JBrowse link
G Isx intestine specific homeobox acts_upstream_of_or_within ISO (MGI:3775349|PMID:18093975) MGI PMID:18093975 MGI:3775349 NCBI chrNW_004955405:42,979,063...43,015,561 JBrowse link
retinal metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca4 ATP binding cassette subfamily A member 4 involved_in ISO (PMID:29847635), (PMID:33375396) UniProt PMID:29847635 PMID:33375396 NCBI chrNW_004955423:612,098...738,702
Ensembl chrNW_004955423:612,098...736,035
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 acts_upstream_of_or_within ISO (MGI:2655944|PMID:12610736) MGI PMID:12610736 MGI:2655944 NCBI chrNW_004955450:16,406,578...16,453,048
Ensembl chrNW_004955450:16,406,436...16,453,180
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family member A3 involved_in ISO (PMID:11585737) UniProt PMID:11585737 NCBI chrNW_004955416:27,823,611...27,858,112
Ensembl chrNW_004955416:27,823,611...27,858,173
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family member A1 involved_in ISO (PMID:11007799) UniProt PMID:11007799 NCBI chrNW_004955439:1,773,884...1,794,325
Ensembl chrNW_004955439:1,773,861...1,794,328
JBrowse link
G Bco1 beta-carotene oxygenase 1 acts_upstream_of_or_within
involved_in
ISO (MGI:5638293|PMID:25701869)
(MGI:3587559|PMID:15951442)
(PMID:17951468)
(PMID:11401432), (PMID:24668807)
MGI
UniProt
PMID:11401432 PMID:15951442 PMID:17951468 PMID:24668807 PMID:25701869 MGI:3587559 MGI:5638293 NCBI chrNW_004955522:3,985,515...4,018,116
Ensembl chrNW_004955522:3,985,266...4,018,886
JBrowse link
G Bco2 beta-carotene oxygenase 2 acts_upstream_of_or_within ISO (MGI:5638293|PMID:25701869) MGI PMID:25701869 MGI:5638293 NCBI chrNW_004955412:13,838,260...13,872,886
Ensembl chrNW_004955412:13,837,782...13,872,886
JBrowse link
G LOC102009223 cytochrome P450 1B1 involved_in ISO (PMID:15258110)
(MGI:5572883|PMID:15258110)
UniProt PMID:15258110 MGI:5572883 NCBI chrNW_004955441:5,803,397...5,812,131
Ensembl chrNW_004955441:5,803,032...5,812,131
JBrowse link
G Rbp4 retinol binding protein 4 acts_upstream_of_or_within ISO (MGI:2150869|PMID:11562477) MGI PMID:11562477 MGI:2150869 NCBI chrNW_004955507:112,342...120,050
Ensembl chrNW_004955507:108,669...120,584
JBrowse link
G Rdh10 retinol dehydrogenase 10 involved_in ISO (PMID:19458327) UniProt PMID:19458327 NCBI chrNW_004955444:6,878,722...6,909,421
Ensembl chrNW_004955444:6,878,722...6,909,421
JBrowse link
G Rdh11 retinol dehydrogenase 11 acts_upstream_of_or_within ISO (PMID:12807874) MGI PMID:12807874 NCBI chrNW_004955466:2,506,641...2,521,506
Ensembl chrNW_004955466:2,508,338...2,520,903
JBrowse link
G Rdh13 retinol dehydrogenase 13 involved_in ISO (PMID:18039331) UniProt PMID:18039331 NCBI chrNW_004955567:1,091,636...1,108,648
Ensembl chrNW_004955567:1,091,636...1,108,732
JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 acts_upstream_of_or_within ISO (MGI:2180434|PMID:11897783) RGD
MGI
PMID:11897783 PMID:21785167 MGI:2180434 RGD:6893661 NCBI chrNW_004955423:23,184,326...23,208,206
Ensembl chrNW_004955423:23,183,937...23,208,282
JBrowse link
G Sdr16c5 short chain dehydrogenase/reductase family 16C member 5 involved_in ISO (PMID:18926804), (PMID:19102727) UniProt PMID:18926804 PMID:19102727 NCBI chrNW_004955454:15,339,353...15,349,180
Ensembl chrNW_004955454:15,339,297...15,351,628
JBrowse link
retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 involved_in ISO (PMID:29240402) RGD
UniProt
PMID:15950969 PMID:21138835 PMID:29240402 RGD:6771322 RGD:6771354 NCBI chrNW_004955450:16,406,578...16,453,048
Ensembl chrNW_004955450:16,406,436...16,453,180
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family member A3 involved_in
acts_upstream_of_or_within
ISO (MGI:3042765|PMID:14623956)
(MGI:1927016|PMID:11044606), (MGI:3055622|PMID:11013254), (MGI:3692370|PMID:16241904)
(PMID:27759097)
RGD
UniProt
MGI
PMID:11013254 PMID:11044606 PMID:14623956 PMID:15950969 PMID:16241904 More... MGI:1927016 MGI:3042765 MGI:3055622 MGI:3692370 RGD:6771322 RGD:6771354 NCBI chrNW_004955416:27,823,611...27,858,112
Ensembl chrNW_004955416:27,823,611...27,858,173
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 ISO RGD PMID:15950969 RGD:6771322 NCBI chrNW_004955545:2,777,523...2,782,567
Ensembl chrNW_004955545:2,777,474...2,782,567
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 ISO RGD PMID:15950969 PMID:21138835 RGD:6771322 RGD:6771354 NCBI chrNW_004955449:5,360,486...5,380,279
Ensembl chrNW_004955449:5,359,617...5,380,267
JBrowse link
G Rbp1 retinol binding protein 1 ISO RGD PMID:15950969 RGD:6771322 NCBI chrNW_004955508:6,046,738...6,072,202
Ensembl chrNW_004955508:6,046,316...6,072,288
JBrowse link
G Rdh10 retinol dehydrogenase 10 acts_upstream_of_or_within ISO (MGI:3709664|PMID:17473173) MGI PMID:17473173 MGI:3709664 NCBI chrNW_004955444:6,878,722...6,909,421
Ensembl chrNW_004955444:6,878,722...6,909,421
JBrowse link
retinoic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102016571 cytochrome P450 2W1 involved_in ISO (PMID:26936974) UniProt PMID:26936974 NCBI chrNW_004955460:8,705,068...8,711,266
Ensembl chrNW_004955460:8,705,068...8,712,121
JBrowse link
G LOC102023166 cytochrome P450 26B1 involved_in ISO (PMID:10823918) RGD
BHF-UCL
PMID:10823918 PMID:21138835 RGD:6771354 NCBI chrNW_004955424:13,336,189...13,355,368
Ensembl chrNW_004955424:13,336,189...13,355,423
JBrowse link
retinoic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide acts_upstream_of_or_within ISO (MGI:3510590|PMID:15193143)
(MGI:1338643|PMID:10358022), (MGI:2675573|PMID:12851412)
MGI PMID:10358022 PMID:12851412 PMID:15193143 MGI:1338643 MGI:2675573 MGI:3510590 NCBI chrNW_004955496:8,136,279...8,149,496 JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide acts_upstream_of_or_within ISO (MGI:1338643|PMID:10358022), (MGI:1340177|PMID:10402668) MGI PMID:10358022 PMID:10402668 MGI:1338643 MGI:1340177 NCBI chrNW_004955496:8,065,943...8,100,878
Ensembl chrNW_004955496:8,065,943...8,102,066
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 acts_upstream_of_or_within ISO (MGI:2681052|PMID:14623241)
(MGI:83148|PMID:8797830)
(MGI:3612223|PMID:16368932)
RGD
MGI
PMID:8797830 PMID:12547725 PMID:14623241 PMID:16368932 MGI:2681052 MGI:3612223 MGI:83148 RGD:1576367 NCBI chrNW_004955450:16,406,578...16,453,048
Ensembl chrNW_004955450:16,406,436...16,453,180
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family member A3 involved_in
acts_upstream_of_or_within
ISO (PMID:11585737)
(MGI:3701419|PMID:17207476)
(MGI:3608158|PMID:16207763)
UniProt
MGI
PMID:11585737 PMID:16207763 PMID:17207476 MGI:3608158 MGI:3701419 NCBI chrNW_004955416:27,823,611...27,858,112
Ensembl chrNW_004955416:27,823,611...27,858,173
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family member A1 involved_in ISO (PMID:11007799) UniProt PMID:11007799 NCBI chrNW_004955439:1,773,884...1,794,325
Ensembl chrNW_004955439:1,773,861...1,794,328
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 acts_upstream_of_or_within ISO (MGI:1313226|PMID:9826179) MGI PMID:9826179 MGI:1313226 NCBI chrNW_004955545:2,777,523...2,782,567
Ensembl chrNW_004955545:2,777,474...2,782,567
JBrowse link
G LOC102010839 cytochrome P450 2S1 involved_in ISO (PMID:12711469) UniProt PMID:12711469 NCBI chrNW_004955555:167,634...183,572
Ensembl chrNW_004955555:168,139...182,196
JBrowse link
G LOC102023166 cytochrome P450 26B1 involved_in ISO (PMID:22020119) UniProt PMID:22020119 NCBI chrNW_004955424:13,336,189...13,355,368
Ensembl chrNW_004955424:13,336,189...13,355,423
JBrowse link
G Rbp1 retinol binding protein 1 acts_upstream_of_or_within ISO (MGI:3510590|PMID:15193143) MGI PMID:15193143 MGI:3510590 NCBI chrNW_004955508:6,046,738...6,072,202
Ensembl chrNW_004955508:6,046,316...6,072,288
JBrowse link
G Scpep1 serine carboxypeptidase 1 ISO RGD PMID:11447226 RGD:70518 NCBI chrNW_004955451:5,847,371...5,876,286
Ensembl chrNW_004955451:5,846,552...5,876,851
JBrowse link
retinol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide acts_upstream_of_or_within ISO (MGI:1338643|PMID:10358022), (MGI:2675573|PMID:12851412)
(MGI:3510590|PMID:15193143)
MGI PMID:10358022 PMID:12851412 PMID:15193143 MGI:1338643 MGI:2675573 MGI:3510590 NCBI chrNW_004955496:8,136,279...8,149,496 JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide acts_upstream_of_or_within ISO (MGI:1338643|PMID:10358022), (MGI:1340177|PMID:10402668) RGD
MGI
PMID:10358022 PMID:10402668 PMID:10829036 MGI:1338643 MGI:1340177 RGD:631904 NCBI chrNW_004955496:8,065,943...8,100,878
Ensembl chrNW_004955496:8,065,943...8,102,066
JBrowse link
G LOC102009223 cytochrome P450 1B1 involved_in ISO (PMID:10681376), (PMID:15258110)
(MGI:5572883|PMID:15258110)
UniProt PMID:10681376 PMID:15258110 MGI:5572883 NCBI chrNW_004955441:5,803,397...5,812,131
Ensembl chrNW_004955441:5,803,032...5,812,131
JBrowse link
G LOC102010322 cytochrome P450 1A2 involved_in ISO (PMID:10681376) UniProt PMID:10681376 NCBI chrNW_004955450:3,165,107...3,171,894
Ensembl chrNW_004955450:3,165,106...3,171,942
JBrowse link
G LOC102010850 cytochrome P450 1A1 involved_in ISO (PMID:10681376) UniProt PMID:10681376 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488
JBrowse link
G Lrat lecithin retinol acyltransferase acts_upstream_of_or_within
involved_in
ISO (MGI:3775853|PMID:18093970)
(MGI:6414681|PMID:28758396)
(PMID:10819989)
RGD
MGI
UniProt
PMID:2253789 PMID:8460936 PMID:9244401 PMID:10819989 PMID:14642897 More... MGI:3775853 MGI:6414681 RGD:1599829 RGD:1599831 RGD:1599832 RGD:6484737 NCBI chrNW_004955471:2,603,395...2,610,988
Ensembl chrNW_004955471:2,603,678...2,609,079
JBrowse link
G Plb1 phospholipase B1 ISO RGD PMID:8117729 RGD:6903951 NCBI chrNW_004955469:10,370,646...10,511,263
Ensembl chrNW_004955469:10,401,178...10,511,057
JBrowse link
G Rbp1 retinol binding protein 1 acts_upstream_of_or_within ISO (MGI:3510590|PMID:15193143)
(MGI:3510590|PMID:15193143), (MGI:3575475|PMID:15765518)
RGD
MGI
PMID:14642897 PMID:15193143 PMID:15765518 MGI:3510590 MGI:3575475 RGD:6484737 NCBI chrNW_004955508:6,046,738...6,072,202
Ensembl chrNW_004955508:6,046,316...6,072,288
JBrowse link
G Rbp4 retinol binding protein 4 involved_in
acts_upstream_of_or_within
ISO (PMID:10232633)
(MGI:3775853|PMID:18093970)
BHF-UCL
MGI
PMID:10232633 PMID:18093970 MGI:3775853 NCBI chrNW_004955507:112,342...120,050
Ensembl chrNW_004955507:108,669...120,584
JBrowse link
G Rdh10 retinol dehydrogenase 10 involved_in ISO (PMID:19458327) UniProt PMID:19458327 NCBI chrNW_004955444:6,878,722...6,909,421
Ensembl chrNW_004955444:6,878,722...6,909,421
JBrowse link
G Rdh11 retinol dehydrogenase 11 involved_in ISO (MGI:6189614|PMID:29567832) UniProt PMID:29567832 MGI:6189614 NCBI chrNW_004955466:2,506,641...2,521,506
Ensembl chrNW_004955466:2,508,338...2,520,903
JBrowse link
G Rdh12 retinol dehydrogenase 12 involved_in ISO (PMID:12226107)
(MGI:5442470|PMID:22621924)
UniProt PMID:12226107 PMID:22621924 MGI:5442470 NCBI chrNW_004955466:2,473,145...2,485,779
Ensembl chrNW_004955466:2,473,096...2,487,623
JBrowse link
G Rdh14 retinol dehydrogenase 14 involved_in
acts_upstream_of_or_within
ISO (MGI:6271140|PMID:12226107)
(MGI:5618338|PMID:25533474)
UniProt
MGI
PMID:12226107 PMID:25533474 MGI:5618338 MGI:6271140 NCBI chrNW_004955469:1,281,391...1,287,334
Ensembl chrNW_004955469:1,281,791...1,286,147
JBrowse link
G Rdh8 retinol dehydrogenase 8 acts_upstream_of_or_within ISO (MGI:3584232|PMID:15755727) MGI PMID:15755727 MGI:3584232 NCBI chrNW_004955495:1,388,385...1,393,209
Ensembl chrNW_004955495:1,388,424...1,392,552
JBrowse link
G Retsat retinol saturase involved_in ISO (MGI:3522397|PMID:15358783) HGNC-UCL PMID:15358783 MGI:3522397 NCBI chrNW_004955424:2,107,602...2,122,029
Ensembl chrNW_004955424:2,107,602...2,122,029
JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 ISO RGD PMID:3603006 RGD:9585656 NCBI chrNW_004955423:23,184,326...23,208,206
Ensembl chrNW_004955423:23,183,937...23,208,282
JBrowse link
G Sdr16c5 short chain dehydrogenase/reductase family 16C member 5 involved_in ISO (PMID:18926804), (PMID:19102727) UniProt PMID:18926804 PMID:19102727 NCBI chrNW_004955454:15,339,353...15,349,180
Ensembl chrNW_004955454:15,339,297...15,351,628
JBrowse link
vitamin A metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrat lecithin retinol acyltransferase involved_in
acts_upstream_of_or_within
ISO (MGI:6414681|PMID:28758396)
(MGI:1928450|PMID:11108736)
RGD
UniProt
MGI
PMID:2253789 PMID:8460936 PMID:9244401 PMID:11108736 PMID:28758396 MGI:1928450 MGI:6414681 RGD:1599829 RGD:1599831 RGD:1599832 NCBI chrNW_004955471:2,603,395...2,610,988
Ensembl chrNW_004955471:2,603,678...2,609,079
JBrowse link
G Ppard peroxisome proliferator activated receptor delta ISO RGD PMID:12576510 RGD:1625187 NCBI chrNW_004955437:3,285,281...3,354,099
Ensembl chrNW_004955437:3,288,830...3,357,048
JBrowse link
G Rbp1 retinol binding protein 1 involved_in ISO (PMID:15632377) UniProt PMID:15632377 NCBI chrNW_004955508:6,046,738...6,072,202
Ensembl chrNW_004955508:6,046,316...6,072,288
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12234
    metabolic process 7789
      cellular metabolic process 6677
        cellular lipid metabolic process 724
          isoprenoid metabolic process 65
            terpenoid metabolic process 50
              diterpenoid metabolic process 45
                retinoid metabolic process 37
                  retinal metabolic process 13
                  retinoic acid metabolic process + 15
                  retinol metabolic process 17
                  vitamin A metabolic process + 5
Path 2
Term Annotations click to browse term
  biological_process 12234
    metabolic process 7789
      primary metabolic process 6948
        lipid metabolic process 978
          cellular lipid metabolic process 724
            isoprenoid metabolic process 65
              terpenoid metabolic process 50
                diterpenoid metabolic process 45
                  retinoid metabolic process 37
                    retinal metabolic process 13
                    retinoic acid metabolic process + 15
                    retinol metabolic process 17
                    vitamin A metabolic process + 5
paths to the root