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ONTOLOGY REPORT - ANNOTATIONS

Term:retinoid metabolic process
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Accession:GO:0001523 term browser browse the term
Definition:The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
Synonyms:exact_synonym: retinoid metabolism


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retinoid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1 alcohol dehydrogenase 1C (class I), gamma polypeptide acts_upstream_of_or_within ISO MGI:2180100 (MGI:2180234|PMID:12027900) RGD PMID:12027900 MGI:2180234 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide involved_in ISO (PMID:15369820) RGD PMID:15369820 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide acts_upstream_of_or_within ISO MGI:2180101 (MGI:2180234|PMID:12027900) RGD PMID:12027900 MGI:2180234 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide involved_in TAS
ISO		 (PMID:16787387), (PMID:9600267) RGD PMID:9600267 PMID:16787387 PMID:10829036 RGD:631904 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 involved_in ISO
ISS		 (PMID:12732097)
GO_REF:0000024		 RGD
UniProt		 PMID:12732097 GO_REF:0000024 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 involved_in ISO (PMID:12732097) RGD PMID:12732097 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 involved_in IDA PMID:7832787 UniProt PMID:7832787 RGD:11558002 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Bco1 beta-carotene oxygenase 1 involved_in ISO
IEA
IDA		 (PMID:11401432)
GO_REF:0000117
(MGI:1931377|PMID:11092891)
PMID:12468597		 RGD
UniProt		 PMID:11092891 PMID:11401432 PMID:12468597 GO_REF:0000117 MGI:1931377, RGD:634627 NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101 		JBrowse link
G Bloc1s1 biogenesis of lysosomal organelles complex-1, subunit 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:1,347,495...1,351,103
Ensembl chr 7:1,340,934...1,351,558 		JBrowse link
G Ces1d carboxylesterase 1D involved_in TAS PMID:12230550 UniProt PMID:12230550 RGD:724430 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces1e carboxylesterase 1E involved_in TAS PMID:12230550 UniProt PMID:12230550 RGD:724430 NCBI chr19:13,833,154...13,869,627
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces1f carboxylesterase 1F involved_in TAS PMID:12230550 UniProt PMID:12230550 RGD:724430 NCBI chr19:13,796,623...13,822,113
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces2a carboxylesterase 2A TAS RGD PMID:12230550 RGD:724430 NCBI chr19:129,428...136,480
Ensembl chr19:129,428...136,480 		JBrowse link
G Ces2c carboxylesterase 2C involved_in TAS PMID:12230550 UniProt PMID:12230550 RGD:724430 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790 		JBrowse link
G Ces2e carboxylesterase 2E involved_in TAS PMID:12230550 UniProt PMID:12230550 RGD:724430 NCBI chr19:157,447...172,822
Ensembl chr19:157,407...172,856 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 IDA RGD PMID:9606960 RGD:1625388 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:5007106 (MGI:5528782|PMID:24005908)		 RGD PMID:24005908 PMID:21873635 MGI:5528782, RGD:13792537 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 involved_in ISO
ISS		 (PMID:12604222)
GO_REF:0000024		 RGD
UniProt		 PMID:12604222 GO_REF:0000024 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127 		JBrowse link
G Rarres2 retinoic acid receptor responder 2 involved_in ISO (PMID:9204961) RGD PMID:9204961 NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556 		JBrowse link
G Rbp3 retinol binding protein 3 IC RGD PMID:8282025 RGD:6893658 NCBI chr16:9,267,538...9,276,006
Ensembl chr16:9,267,538...9,276,006 		JBrowse link
G Rdh11 retinol dehydrogenase 11 involved_in ISO (PMID:12226107) RGD PMID:12226107 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252 		JBrowse link
G Rdh16 retinol dehydrogenase 16 involved_in ISO (MGI:1101408|PMID:9407098) RGD PMID:9407098 MGI:1101408 NCBI chr 7:63,616,724...63,624,120
Ensembl chr 7:63,597,536...63,624,124 		JBrowse link
G Rdh5 retinol dehydrogenase 5 involved_in ISO
IBA		 (PMID:9931293)
PMID:21873635
(MGI:1350674|PMID:10588954)		 RGD PMID:9931293 PMID:10588954 PMID:21873635 MGI:1350674, RGD:13792537 NCBI chr 7:1,340,545...1,347,361
Ensembl chr 7:1,340,934...1,351,558 		JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 involved_in ISO (PMID:25112876)
(PMID:16150724)		 RGD PMID:16150724 PMID:25112876 NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403 		JBrowse link
9-cis-retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 acts_upstream_of_or_within ISO (MGI:2662611|PMID:11876656) RGD PMID:11876656 MGI:2662611 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 acts_upstream_of_or_within ISO (MGI:2662611|PMID:11876656) RGD PMID:11876656 MGI:2662611 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 acts_upstream_of_or_within ISO (MGI:2662611|PMID:11876656) RGD PMID:11876656 MGI:2662611 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA 9-cis- and all-trans-retinoic acid synthesized from 9-cis- and all-trans-retinal RGD PMID:8765131 RGD:2306683 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in ISO
ISS		 (PMID:11304534)
GO_REF:0000024		 RGD
UniProt		 PMID:11304534 GO_REF:0000024 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Rdh16 retinol dehydrogenase 16 acts_upstream_of_or_within ISO (MGI:2662611|PMID:11876656) RGD PMID:11876656 MGI:2662611 NCBI chr 7:63,616,724...63,624,120
Ensembl chr 7:63,597,536...63,624,124 		JBrowse link
9-cis-retinoic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IDA RGD PMID:17167544 RGD:2306320 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:21851338) RGD PMID:21851338 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Prmt3 protein arginine methyltransferase 3 involved_in ISO
ISS		 (PMID:33495566)
GO_REF:0000024		 RGD
UniProt		 PMID:33495566 GO_REF:0000024 NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435 		JBrowse link
positive regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rdh10 retinol dehydrogenase 10 IMP RGD PMID:21138835 RGD:6771354 NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572 		JBrowse link
G Rdh16 retinol dehydrogenase 16 IMP RGD PMID:21138835 RGD:6771354 NCBI chr 7:63,616,724...63,624,120
Ensembl chr 7:63,597,536...63,624,124 		JBrowse link
regulation of vitamin A metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgat1 diacylglycerol O-acyltransferase 1 IMP RGD PMID:18000880 RGD:10400849 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Isx intestine-specific homeobox acts_upstream_of_or_within ISO MGI:3775943 (MGI:3775349|PMID:18093975) RGD PMID:18093975 MGI:3775349 NCBI chr19:13,218,552...13,239,754
Ensembl chr19:13,218,552...13,239,760 		JBrowse link
retinal metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca4 ATP binding cassette subfamily A member 4 involved_in ISO (PMID:29847635), (PMID:33375396) RGD PMID:29847635 PMID:33375396 NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 IDA RGD PMID:20709016 RGD:6903952 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 involved_in ISO (PMID:21851338) RGD PMID:21851338 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:21851338) RGD PMID:21851338 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 acts_upstream_of_or_within ISO (MGI:2655944|PMID:12610736) RGD PMID:12610736 MGI:2655944 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11585737)		 Ensembl
RGD		 PMID:11585737 GO_REF:0000107 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 involved_in ISO (PMID:11007799) RGD PMID:11007799 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385 		JBrowse link
G Bco1 beta-carotene oxygenase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA
ISS		 MGI:2177469 (MGI:5638293|PMID:25701869)
PMID:21873635
GO_REF:0000024
(MGI:3587559|PMID:15951442)
(PMID:11401432), (PMID:17951468), (PMID:24668807)		 RGD
UniProt		 PMID:11401432 PMID:15951442 PMID:17951468 PMID:24668807 PMID:25701869 More... GO_REF:0000024 MGI:3587559 MGI:5638293, RGD:13792537 NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101 		JBrowse link
G Bco2 beta-carotene oxygenase 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1926923 (MGI:5638293|PMID:25701869)
PMID:21873635		 RGD PMID:25701869 PMID:21873635 MGI:5638293, RGD:13792537 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5572883|PMID:15258110)
GO_REF:0000024
(PMID:15258110)		 Ensembl
RGD
UniProt		 PMID:15258110 GO_REF:0000024 GO_REF:0000107 MGI:5572883 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2655870|PMID:12680773)
PMID:21873635		 RGD PMID:12680773 PMID:21873635 MGI:2655870, RGD:13792537 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127 		JBrowse link
G Rbp4 retinol binding protein 4 acts_upstream_of_or_within ISO MGI:2445721 (MGI:2150869|PMID:11562477) RGD PMID:11562477 MGI:2150869 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G Rdh10 retinol dehydrogenase 10 involved_in ISO (PMID:19458327) RGD PMID:19458327 NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572 		JBrowse link
G Rdh11 retinol dehydrogenase 11 acts_upstream_of_or_within ISO (PMID:12807874) RGD PMID:12807874 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252 		JBrowse link
G Rdh13 retinol dehydrogenase 13 involved_in IBA
ISO		 PMID:21873635
(PMID:18039331)		 RGD PMID:18039331 PMID:21873635 RGD:13792537 NCBI chr 1:69,373,014...69,401,454
Ensembl chr 1:69,373,113...69,400,908 		JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 acts_upstream_of_or_within IMP
ISO		 MGI:2181399 (MGI:2180434|PMID:11897783) RGD PMID:11897783 PMID:21785167 MGI:2180434, RGD:6893661 NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403 		JBrowse link
G Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 involved_in IBA
ISO		 PMID:21873635
(PMID:18926804), (PMID:19102727)		 RGD PMID:18926804 PMID:19102727 PMID:21873635 RGD:13792537 NCBI chr 5:17,018,813...17,043,974
Ensembl chr 5:17,018,813...17,040,970 		JBrowse link
retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IMP RGD PMID:21138835 RGD:6771354 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 involved_in IEP
ISO
ISS
IMP		 (PMID:29240402)
GO_REF:0000024		 RGD
UniProt		 PMID:29240402 PMID:15950969 PMID:21138835 GO_REF:0000024, RGD:6771322, RGD:6771354 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 acts_upstream_of_or_within
involved_in		 IEP
ISO
ISS
IEA
IMP		 (MGI:1927016|PMID:11044606), (MGI:3055622|PMID:11013254), (MGI:3692370|PMID:16241904)
(MGI:3042765|PMID:14623956)
(PMID:27759097)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:11013254 PMID:11044606 PMID:14623956 PMID:16241904 PMID:27759097 More... GO_REF:0000024 GO_REF:0000107 MGI:1927016 MGI:3042765 MGI:3055622 MGI:3692370, RGD:6771322, RGD:6771354 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 IEP RGD PMID:15950969 RGD:6771322 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 IEP
IDA		 RGD PMID:15950969 PMID:21138835 RGD:6771322, RGD:6771354 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Rbp1 retinol binding protein 1 IEP RGD PMID:15950969 RGD:6771322 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
G Rdh10 retinol dehydrogenase 10 acts_upstream_of_or_within ISO (MGI:3709664|PMID:17473173) RGD PMID:17473173 MGI:3709664 NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572 		JBrowse link
retinoic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crabp1 cellular retinoic acid binding protein 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 involved_in ISO (PMID:10823918)
(MGI:894533|PMID:9250660)		 RGD PMID:9250660 PMID:10823918 MGI:894533 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 involved_in IMP
ISO		 (PMID:10823918) RGD PMID:10823918 PMID:21138835 RGD:6771354 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 involved_in ISO (PMID:14532297) RGD PMID:14532297 NCBI chr 1:235,458,961...235,468,433
Ensembl chr 1:235,459,356...235,466,842 		JBrowse link
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 involved_in ISO (PMID:26936974) RGD PMID:26936974 NCBI chr12:15,291,552...15,296,421
Ensembl chr12:15,291,704...15,296,421 		JBrowse link
retinoic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1 alcohol dehydrogenase 1C (class I), gamma polypeptide involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
MGI:2180099|MGI:2180100|MGI:97876 (MGI:1338643|PMID:10358022), (MGI:2675573|PMID:12851412), (MGI:3510590|PMID:15193143)
GO_REF:0000107		 RGD
Ensembl		 PMID:10358022 PMID:12851412 PMID:15193143 PMID:21873635 GO_REF:0000107 MGI:1338643 MGI:2675573 MGI:3510590, RGD:13792537 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534 		JBrowse link
G Adh6a alcohol dehydrogenase 6A (class V) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:226,823,775...226,846,005
Ensembl chr 2:226,823,730...226,846,003 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
MGI:2180102 (MGI:1338643|PMID:10358022), (MGI:1340177|PMID:10402668)
GO_REF:0000107		 RGD
Ensembl		 PMID:10358022 PMID:10402668 PMID:21873635 GO_REF:0000107 MGI:1338643 MGI:1340177, RGD:13792537 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 acts_upstream_of_or_within ISO MGI:1861722|MGI:2667220|MGI:3609477 (MGI:1336449|PMID:10191271), (MGI:2664447|PMID:12808103), (MGI:2675573|PMID:12851412), (MGI:3608158|PMID:16207763) RGD PMID:10191271 PMID:12808103 PMID:12851412 PMID:16207763 MGI:1336449 MGI:2664447 MGI:2675573 MGI:3608158 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 acts_upstream_of_or_within TAS
ISO
IDA		 MGI:1857891|MGI:2180721 (MGI:2681052|PMID:14623241), (MGI:3612223|PMID:16368932), (MGI:83148|PMID:8797830) RGD PMID:8797830 PMID:14623241 PMID:16368932 PMID:15205379 PMID:12547725 MGI:2681052 MGI:3612223 MGI:83148, RGD:1576366, RGD:1576367 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 involved_in
acts_upstream_of_or_within		 ISO (PMID:11585737)
MGI:1353450|MGI:3043947|MGI:3512079 (MGI:3608158|PMID:16207763), (MGI:3701419|PMID:17207476)		 RGD PMID:11585737 PMID:16207763 PMID:17207476 MGI:3608158 MGI:3701419 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 involved_in ISO
IBA		 (PMID:11007799)
PMID:21873635		 RGD PMID:11007799 PMID:21873635 RGD:13792537 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 acts_upstream_of_or_within NAS
ISO		 (MGI:1313226|PMID:9826179) RGD PMID:9826179 PMID:7750498 MGI:1313226, RGD:61557 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:22020119), (PMID:9716180)
(MGI:1195386|PMID:9442090), (MGI:894533|PMID:9250660)
MGI:2183292 (MGI:3522528|PMID:15531370)		 RGD PMID:9250660 PMID:9442090 PMID:9716180 PMID:15531370 PMID:22020119 MGI:1195386 MGI:3522528 MGI:894533 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22020119)		 UniProt
RGD		 PMID:22020119 GO_REF:0000024 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 involved_in ISO (PMID:11093772) RGD PMID:11093772 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:11093772) RGD PMID:11093772
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 involved_in ISO (PMID:12711469) RGD PMID:12711469 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:11093772) RGD PMID:11093772 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 involved_in ISO (PMID:11093772) RGD PMID:11093772 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 NAS RGD PMID:12390888 RGD:633755 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Rbp1 retinol binding protein 1 acts_upstream_of_or_within ISO MGI:2181412|MGI:87921 (MGI:3510590|PMID:15193143) RGD PMID:15193143 MGI:3510590 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
G Rdh16 retinol dehydrogenase 16 IDA RGD PMID:7499345 RGD:1299624 NCBI chr 7:63,616,724...63,624,120
Ensembl chr 7:63,597,536...63,624,124 		JBrowse link
G Scpep1 serine carboxypeptidase 1 IEP RGD PMID:11447226 RGD:70518 NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850 		JBrowse link
retinol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1 alcohol dehydrogenase 1C (class I), gamma polypeptide involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
MGI:2180099|MGI:2180100|MGI:97876 (MGI:1338643|PMID:10358022), (MGI:2675573|PMID:12851412), (MGI:3510590|PMID:15193143)		 Ensembl
RGD		 PMID:10358022 PMID:12851412 PMID:15193143 PMID:21873635 GO_REF:0000107 MGI:1338643 MGI:2675573 MGI:3510590, RGD:13792537 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide involved_in ISO
ISS		 (PMID:16787387), (PMID:17279314)
GO_REF:0000024		 RGD
UniProt		 PMID:16787387 PMID:17279314 GO_REF:0000024 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534 		JBrowse link
G Adh6a alcohol dehydrogenase 6A (class V) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:226,823,775...226,846,005
Ensembl chr 2:226,823,730...226,846,003 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide acts_upstream_of_or_within
involved_in		 IDA
ISO
IEA
IBA		 MGI:2180102 (MGI:1338643|PMID:10358022), (MGI:1340177|PMID:10402668)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:10358022 PMID:10402668 PMID:10829036 PMID:21873635 GO_REF:0000107 MGI:1338643 MGI:1340177, RGD:631904, RGD:13792537 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 IDA RGD PMID:20709016 RGD:6903952 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000041
MGI:2667220 (MGI:2675573|PMID:12851412)		 UniProt
RGD		 PMID:12851412 GO_REF:0000041 MGI:2675573 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Awat2 acyl-CoA wax alcohol acyltransferase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:65,482,240...65,490,500
Ensembl chr  X:65,481,929...65,527,625 		JBrowse link
G Bco1 beta-carotene oxygenase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101 		JBrowse link
G Cel carboxyl ester lipase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
G Ces1d carboxylesterase 1D involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces1e carboxylesterase 1E involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:13,833,154...13,869,627
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces1f carboxylesterase 1F involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:13,796,623...13,822,113
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces2a carboxylesterase 2A involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:129,428...136,480
Ensembl chr19:129,428...136,480 		JBrowse link
G Ces2c carboxylesterase 2C involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790 		JBrowse link
G Ces2e carboxylesterase 2E involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:157,447...172,822
Ensembl chr19:157,407...172,856 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000041
(PMID:10681376)		 UniProt
RGD		 PMID:10681376 GO_REF:0000024 GO_REF:0000041 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in IEA
ISS
ISO		 GO_REF:0000041
GO_REF:0000024
(PMID:10681376)		 UniProt
RGD		 PMID:10681376 GO_REF:0000024 GO_REF:0000041 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IEA
ISO
ISS		 GO_REF:0000002
(MGI:5572883|PMID:15258110)
GO_REF:0000041
(PMID:10681376), (PMID:15258110)
GO_REF:0000107
GO_REF:0000024		 InterPro
RGD
UniProt
Ensembl		 PMID:10681376 PMID:15258110 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 MGI:5572883 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in ISO (PMID:10681376) RGD PMID:10681376 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:10681376) RGD PMID:10681376 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425 		JBrowse link
G Lipe lipase E, hormone sensitive type involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310 		JBrowse link
G Lrat lecithin retinol acyltransferase involved_in
acts_upstream_of_or_within		 IDA
IBA
ISO
IEA		 PMID:21873635
(MGI:6414681|PMID:28758396)
MGI:3038935|MGI:97879 (MGI:3775853|PMID:18093970)
(PMID:10819989)
GO_REF:0000041		 RGD
UniProt		 PMID:10819989 PMID:18093970 PMID:28758396 PMID:2253789 PMID:21873635 More... GO_REF:0000041 MGI:3775853 MGI:6414681, RGD:1599829, RGD:13792537, RGD:6484737, RGD:1599832, RGD:1599831 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619 		JBrowse link
G Plb1 phospholipase B1 IDA RGD PMID:8117729 RGD:6903951 NCBI chr 6:24,087,051...24,227,167
Ensembl chr 6:24,089,214...24,210,117 		JBrowse link
G Pnlip pancreatic lipase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:257,774,012...257,811,656
Ensembl chr 1:257,798,581...257,811,654 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805 		JBrowse link
G Pnpla4 patatin like phospholipase domain containing 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:42,313,554...42,318,451
Ensembl chr  X:42,305,373...42,318,552 		JBrowse link
G Rbp1 retinol binding protein 1 acts_upstream_of_or_within IDA
ISO		 MGI:2181412|MGI:87921 (MGI:3510590|PMID:15193143), (MGI:3575475|PMID:15765518) RGD PMID:15193143 PMID:15765518 PMID:14642897 MGI:3510590 MGI:3575475, RGD:6484737 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
G Rbp2 retinol binding protein 2 TAS RGD PMID:3029082 RGD:729693 NCBI chr 8:99,079,293...99,104,489
Ensembl chr 8:99,079,104...99,104,473 		JBrowse link
G Rbp4 retinol binding protein 4 involved_in
acts_upstream_of_or_within		 ISO (PMID:10232633)
MGI:1891259 (MGI:3775853|PMID:18093970)		 RGD PMID:10232633 PMID:18093970 MGI:3775853 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G Rdh10 retinol dehydrogenase 10 involved_in ISO
IEA		 (PMID:19458327)
GO_REF:0000041		 RGD
UniProt		 PMID:19458327 GO_REF:0000041 NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572 		JBrowse link
G Rdh11 retinol dehydrogenase 11 involved_in ISO (MGI:6189614|PMID:29567832) RGD PMID:29567832 MGI:6189614 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252 		JBrowse link
G Rdh12 retinol dehydrogenase 12 involved_in ISO (PMID:12226107)
(MGI:5442470|PMID:22621924)		 RGD PMID:12226107 PMID:22621924 MGI:5442470 NCBI chr 6:98,015,465...98,028,388
Ensembl chr 6:98,015,465...98,028,388 		JBrowse link
G Rdh13 retinol dehydrogenase 13 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:69,373,014...69,401,454
Ensembl chr 1:69,373,113...69,400,908 		JBrowse link
G Rdh14 retinol dehydrogenase 14 acts_upstream_of_or_within
involved_in		 ISO (MGI:5618338|PMID:25533474)
(MGI:6271140|PMID:12226107)		 RGD PMID:12226107 PMID:25533474 MGI:5618338 MGI:6271140 NCBI chr 6:33,156,569...33,161,712
Ensembl chr 6:33,156,569...33,161,712 		JBrowse link
G Rdh16 retinol dehydrogenase 16 involved_in IDA
IBA
IEA		 PMID:21873635
GO_REF:0000041		 UniProt
RGD		 PMID:7499345 PMID:21873635 GO_REF:0000041, RGD:1299624, RGD:13792537 NCBI chr 7:63,616,724...63,624,120
Ensembl chr 7:63,597,536...63,624,124 		JBrowse link
G Rdh7 retinol dehydrogenase 7 involved_in IEA
IBA		 GO_REF:0000041
PMID:21873635		 UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 7:63,676,016...63,689,375
Ensembl chr 7:63,675,579...63,689,392 		JBrowse link
G Rdh8 retinol dehydrogenase 8 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3584232|PMID:15755727)
PMID:21873635		 RGD PMID:15755727 PMID:21873635 MGI:3584232, RGD:13792537 NCBI chr 8:19,353,191...19,360,462
Ensembl chr 8:19,353,191...19,360,462 		JBrowse link
G Retsat retinol saturase involved_in ISS
IBA
ISO
IEA		 PMID:15358783
PMID:21873635
(MGI:3522397|PMID:15358783)
GO_REF:0000107		 RGD
Ensembl		 PMID:15358783 PMID:15358783 PMID:21873635 GO_REF:0000107 MGI:3522397, RGD:8553455, RGD:13792537 NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310 		JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 IDA RGD PMID:3603006 RGD:9585656 NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403 		JBrowse link
G Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 involved_in IBA
ISO		 PMID:21873635
(PMID:18926804), (PMID:19102727)		 RGD PMID:18926804 PMID:19102727 PMID:21873635 RGD:13792537 NCBI chr 5:17,018,813...17,043,974
Ensembl chr 5:17,018,813...17,040,970 		JBrowse link
G Sdr9c7 short chain dehydrogenase/reductase family 9C, member 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:63,703,788...63,720,325
Ensembl chr 7:63,707,071...63,721,480 		JBrowse link
G Ttr transthyretin involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
vitamin A metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrat lecithin retinol acyltransferase involved_in
acts_upstream_of_or_within		 IDA
IBA
ISO		 PMID:21873635
(MGI:6414681|PMID:28758396)
(MGI:1928450|PMID:11108736)		 RGD PMID:11108736 PMID:28758396 PMID:2253789 PMID:21873635 PMID:9244401 More... MGI:1928450 MGI:6414681, RGD:1599829, RGD:13792537, RGD:1599832, RGD:1599831 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IMP RGD PMID:12576510 RGD:1625187 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Rbp1 retinol binding protein 1 involved_in ISO
ISS		 (PMID:15632377)
GO_REF:0000024		 RGD
UniProt		 PMID:15632377 GO_REF:0000024 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    metabolic process 12347
      cellular metabolic process 10465
        cellular lipid metabolic process 1057
          isoprenoid metabolic process 127
            terpenoid metabolic process 98
              diterpenoid metabolic process 87
                retinoid metabolic process 78
                  retinal metabolic process 17
                  retinoic acid metabolic process + 27
                  retinol metabolic process 54
                  vitamin A metabolic process + 5
Path 2
Term Annotations click to browse term
  biological_process 20094
    metabolic process 12347
      primary metabolic process 11099
        lipid metabolic process 1446
          cellular lipid metabolic process 1057
            isoprenoid metabolic process 127
              terpenoid metabolic process 98
                diterpenoid metabolic process 87
                  retinoid metabolic process 78
                    retinal metabolic process 17
                    retinoic acid metabolic process + 27
                    retinol metabolic process 54
                    vitamin A metabolic process + 5
paths to the root