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ONTOLOGY REPORT - ANNOTATIONS

Term:neurotransmitter uptake
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Accession:GO:0001504 term browser browse the term
Definition:The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
Synonyms:exact_synonym: neurotransmitter import
 narrow_synonym: neurotransmitter import into glial cell;   neurotransmitter import into neuron
 broad_synonym: neurotransmitter recycling

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neurotransmitter uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12805306) Ensembl
MGI		 PMID:12805306 GO_REF:0000107 NCBI chrNW_004936740:489,357...514,235
Ensembl chrNW_004936740:488,154...514,308 		JBrowse link
G Slc17a6 solute carrier family 17 member 6 acts_upstream_of_or_within ISO (PMID:11432869) MGI PMID:11432869 NCBI chrNW_004936654:3,039,825...3,082,788
Ensembl chrNW_004936654:3,040,312...3,083,669 		JBrowse link
G Slc1a6 solute carrier family 1 member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:5,464,850...5,478,763
Ensembl chrNW_004936596:5,464,862...5,478,641 		JBrowse link
G Slc1a7 solute carrier family 1 member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936522:7,928,847...7,972,618
Ensembl chrNW_004936522:7,928,742...7,973,399 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 (Augustine blood group) involved_in ISO (MGI:5902903|PMID:28069792) ARUK-UCL PMID:28069792 MGI:5902903 NCBI chrNW_004936476:15,849,054...15,862,486
Ensembl chrNW_004936476:15,846,606...15,862,548 		JBrowse link
G Slc29a2 solute carrier family 29 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:3,210,463...3,221,012
Ensembl chrNW_004936599:3,211,939...3,223,348 		JBrowse link
G Slc6a11 solute carrier family 6 member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936602:2,437,653...2,564,309
Ensembl chrNW_004936602:2,439,813...2,564,313 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936815:359,775...400,690
Ensembl chrNW_004936815:359,775...400,690 		JBrowse link
G Slc6a5 solute carrier family 6 member 5 involved_in ISO (PMID:14622583) SynGO PMID:14622583 NCBI chrNW_004936654:1,525,843...1,576,220
Ensembl chrNW_004936654:1,525,843...1,576,220 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 involved_in ISO (PMID:1618338) SynGO PMID:1618338 NCBI chrNW_004936474:25,312,544...25,344,993
Ensembl chrNW_004936474:25,313,201...25,345,053 		JBrowse link
dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:9886065) Ensembl
MGI		 PMID:9886065 GO_REF:0000107 NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15721235) Ensembl
MGI		 PMID:15721235 GO_REF:0000107 NCBI chrNW_004936623:2,422,780...2,436,817
Ensembl chrNW_004936623:2,422,833...2,436,817 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12915482) Ensembl
MGI		 PMID:12915482 GO_REF:0000107 NCBI chrNW_004936489:12,118,538...12,913,664
Ensembl chrNW_004936489:12,120,678...13,327,872 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936475:7,937,920...7,973,563
Ensembl chrNW_004936475:7,938,519...7,973,538 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936815:359,775...400,690
Ensembl chrNW_004936815:359,775...400,690 		JBrowse link
glutamate reuptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln8 CLN8 transmembrane ER and ERGIC protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8095977), (PMID:9600674) Ensembl
MGI		 PMID:8095977 PMID:9600674 GO_REF:0000107 NCBI chrNW_004936615:993,092...999,976
Ensembl chrNW_004936615:985,634...1,003,172 		JBrowse link
G Kcnj10 potassium inwardly rectifying channel subfamily J member 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17942730) Ensembl
MGI		 PMID:17942730 GO_REF:0000107 NCBI chrNW_004936740:555,948...589,219
Ensembl chrNW_004936740:555,998...586,353 		JBrowse link
histamine uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a2 solute carrier family 18 member A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936486:7,075,373...7,108,984
Ensembl chrNW_004936486:7,075,358...7,109,637 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:11,605,403...11,627,786
Ensembl chrNW_004936489:11,594,480...11,627,786 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16061728) Ensembl
MGI		 PMID:16061728 GO_REF:0000107 NCBI chrNW_004936489:11,693,755...11,774,380
Ensembl chrNW_004936489:11,693,755...11,772,628 		JBrowse link
G Slc29a4 solute carrier family 29 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936765:854,712...868,001
Ensembl chrNW_004936765:855,667...864,900 		JBrowse link
negative regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936685:2,077,017...2,175,298
Ensembl chrNW_004936685:2,076,651...2,175,338 		JBrowse link
negative regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpm6b glycoprotein M6B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936470:3,332,856...3,496,178
Ensembl chrNW_004936470:3,332,859...3,496,615 		JBrowse link
G Nos1 nitric oxide synthase 1 involved_in ISO (MGI:3710710|PMID:17452640) UniProt PMID:17452640 MGI:3710710 NCBI chrNW_004936558:5,162,471...5,302,488
Ensembl chrNW_004936558:5,233,459...5,301,414 		JBrowse link
G Slc18a1 solute carrier family 18 member A1 ISO G-protein mediated uptake inhibition RGD PMID:16926160 RGD:5130998 NCBI chrNW_004936555:4,249,821...4,271,379
Ensembl chrNW_004936555:4,249,821...4,271,379 		JBrowse link
G Snca synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936685:2,077,017...2,175,298
Ensembl chrNW_004936685:2,076,651...2,175,338 		JBrowse link
neurotransmitter reuptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc1a2 solute carrier family 1 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936533:2,779,650...2,918,640
Ensembl chrNW_004936533:2,779,518...2,918,298 		JBrowse link
G Slc6a1 solute carrier family 6 member 1 involved_in ISO PMID:1975955
(PMID:12815026)		 SynGO PMID:1975955 PMID:12815026 RGD:632739 NCBI chrNW_004936602:2,359,151...2,397,346
Ensembl chrNW_004936602:2,357,607...2,379,061 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:7,937,920...7,973,563
Ensembl chrNW_004936475:7,938,519...7,973,538 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:6,205,268...6,239,062
Ensembl chrNW_004936538:6,205,251...6,239,083 		JBrowse link
G Slc6a5 solute carrier family 6 member 5 involved_in ISO (PMID:23486948) SynGO PMID:23486948 NCBI chrNW_004936654:1,525,843...1,576,220
Ensembl chrNW_004936654:1,525,843...1,576,220 		JBrowse link
positive regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9886065) Ensembl
MGI		 PMID:9886065 GO_REF:0000107 NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798 		JBrowse link
G Nat8l N-acetyltransferase 8 like involved_in ISO (MGI:4943664|PMID:19014384) UniProt PMID:19014384 MGI:4943664 NCBI chrNW_004936477:21,397,729...21,405,098 JBrowse link
G Rab3b RAB3B, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936522:8,924,724...8,985,309
Ensembl chrNW_004936522:8,924,617...8,989,734 		JBrowse link
positive regulation of glutamate uptake involved in transmission of nerve impulse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb1 integrin subunit beta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5629870|PMID:25716834) ARUK-UCL
Ensembl		 PMID:25716834 GO_REF:0000107 MGI:5629870 NCBI chrNW_004936574:1,465,981...1,495,717
Ensembl chrNW_004936574:1,465,897...1,495,762 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:13,436,136...13,486,173
Ensembl chrNW_004936492:13,435,848...13,486,169 		JBrowse link
positive regulation of neurotransmitter uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:12,118,538...12,913,664
Ensembl chrNW_004936489:12,120,678...13,327,872 		JBrowse link
regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12223553) Ensembl
MGI		 PMID:12223553 GO_REF:0000107 NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936518:4,291,391...4,310,752
Ensembl chrNW_004936518:4,288,154...4,310,753 		JBrowse link
G Tor1a torsin family 1 member A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:17,012,661...17,020,657
Ensembl chrNW_004936487:17,011,670...17,020,699 		JBrowse link
regulation of glutamate uptake involved in transmission of nerve impulse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Per2 period circadian regulator 2 involved_in ISO (MGI:3687603|PMID:16595674) UniProt PMID:16595674 MGI:3687603 NCBI chrNW_004936525:221,601...263,284
Ensembl chrNW_004936525:221,510...263,295 		JBrowse link
regulation of neurotransmitter uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO (PMID:19118188) ARUK-UCL PMID:19118188 NCBI chrNW_004936640:1,549,977...1,787,436
Ensembl chrNW_004936640:1,550,167...1,787,286 		JBrowse link
G Arl6ip5 ADP ribosylation factor like GTPase 6 interacting protein 5 involved_in ISO PMID:11242046 SynGO PMID:11242046 RGD:1299537 NCBI chrNW_004936603:1,524,959...1,549,923
Ensembl chrNW_004936603:1,524,625...1,549,923 		JBrowse link
G Drd2 dopamine receptor D2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798 		JBrowse link
G Drd3 dopamine receptor D3 involved_in ISO (PMID:27393374) SynGO PMID:27393374 NCBI chrNW_004936536:1,580,732...1,616,726
Ensembl chrNW_004936536:1,580,732...1,616,725 		JBrowse link
G Flot1 flotillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936837:387,012...401,076
Ensembl chrNW_004936837:380,288...401,071 		JBrowse link
G Gfap glial fibrillary acidic protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15135219) Ensembl
MGI		 PMID:15135219 GO_REF:0000107 NCBI chrNW_004936541:1,265,915...1,275,232
Ensembl chrNW_004936541:1,265,436...1,275,296 		JBrowse link
G Syngr3 synaptogyrin 3 involved_in ISO PMID:19357284 SynGO PMID:19357284 RGD:13702442 NCBI chrNW_004936694:2,043,646...2,047,897
Ensembl chrNW_004936694:2,043,657...2,047,883 		JBrowse link
regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:2,822,789...2,871,069
Ensembl chrNW_004936541:2,815,738...2,871,035 		JBrowse link
serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a1 solute carrier family 18 member A1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:19008227 GO_REF:0000107 RGD:5131091 NCBI chrNW_004936555:4,249,821...4,271,379
Ensembl chrNW_004936555:4,249,821...4,271,379 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20007701 GO_REF:0000107 RGD:5130957 NCBI chrNW_004936486:7,075,373...7,108,984
Ensembl chrNW_004936486:7,075,358...7,109,637 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936728:703,688...706,317
Ensembl chrNW_004936728:704,290...705,885 		JBrowse link
G Slc18b1 solute carrier family 18 member B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936560:790,063...819,275
Ensembl chrNW_004936560:786,676...819,319 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:11,534,095...11,556,759
Ensembl chrNW_004936489:11,534,095...11,556,745 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:11,605,403...11,627,786
Ensembl chrNW_004936489:11,594,480...11,627,786 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:11,693,755...11,774,380
Ensembl chrNW_004936489:11,693,755...11,772,628 		JBrowse link
G Slc29a4 solute carrier family 29 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936765:854,712...868,001
Ensembl chrNW_004936765:855,667...864,900 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:12944413 GO_REF:0000107 GO_REF:0000118 RGD:1580638 NCBI chrNW_004936538:6,205,268...6,239,062
Ensembl chrNW_004936538:6,205,251...6,239,083 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    localization 5176
      establishment of localization 4485
        transport 4184
          import into cell 901
            neurotransmitter uptake 44
              histamine uptake + 4
              negative regulation of neurotransmitter uptake + 4
              neurotransmitter reuptake + 30
              positive regulation of neurotransmitter uptake + 6
              regulation of neurotransmitter uptake + 20
paths to the root