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ONTOLOGY REPORT - ANNOTATIONS

Term:neurotransmitter uptake
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Accession:GO:0001504 term browser browse the term
Definition:The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
Synonyms:exact_synonym: neurotransmitter import
 narrow_synonym: neurotransmitter import into glial cell;   neurotransmitter import into neuron
 broad_synonym: neurotransmitter recycling
 xref: Reactome:R-HSA-112313 "Neurotransmitter uptake and metabolism In glial cells"


show annotations for term's descendants           Sort by:
neurotransmitter uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 acts_upstream_of_or_within
involved_in 		IEA
ISO 		(PMID:12805306) Ensembl
ARUK-UCL		 PMID:12805306 GO_REF:0000107 NCBI chr 1:135,469,495...135,497,303
Ensembl chr 1:139,390,549...139,418,303 		JBrowse link
G SLC17A6 solute carrier family 17 member 6 acts_upstream_of_or_within ISO (PMID:11432869) MGI PMID:11432869 NCBI chr11:22,350,537...22,392,009
Ensembl chr11:22,258,011...22,301,944 		JBrowse link
G SLC17A7 solute carrier family 17 member 7 acts_upstream_of_or_within ISO (PMID:15103023) MGI PMID:15103023 NCBI chr19:46,443,076...46,455,195
Ensembl chr19:55,365,811...55,377,438 		JBrowse link
G SLC1A6 solute carrier family 1 member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:14,499,333...14,529,781
Ensembl chr19:15,470,222...15,526,471 		JBrowse link
G SLC1A7 solute carrier family 1 member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:52,359,809...52,415,466
Ensembl chr 1:53,960,400...54,015,396 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:43,815,006...43,830,290
Ensembl chr 6:45,099,243...45,113,689 		JBrowse link
G SLC29A2 solute carrier family 29 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,728,204...61,738,174
Ensembl chr11:65,054,041...65,063,540 		JBrowse link
G SLC6A11 solute carrier family 6 member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,753,412...10,878,333
Ensembl chr 3:11,101,336...11,222,948 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:1,437,567...1,488,829 JBrowse link
G SLC6A5 solute carrier family 6 member 5 involved_in ISO (PMID:14622583) SynGO PMID:14622583 NCBI chr11:20,627,557...20,691,347
Ensembl chr11:20,538,054...20,592,893 		JBrowse link
G SLC6A9 solute carrier family 6 member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:43,298,326...43,333,345
Ensembl chr 1:44,664,839...44,704,882 		JBrowse link
dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G PARK7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:15721235) MGI PMID:15721235 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:35,885,756...35,935,638
Ensembl chr16:54,990,773...55,040,504 		JBrowse link
glutamate reuptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN8 CLN8 transmembrane ER and ERGIC protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:5,587,875...5,606,883
Ensembl chr 8:1,658,694...1,700,754 		JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 acts_upstream_of_or_within ISO (PMID:17942730) MGI PMID:17942730 NCBI chr 1:135,391,321...135,424,100 JBrowse link
histamine uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC18A2 solute carrier family 18 member A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:113,823,005...113,862,451
Ensembl chr10:117,250,639...117,290,064 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:158,058,226...158,150,917
Ensembl chr 6:163,065,317...163,158,931 		JBrowse link
G SLC22A3 solute carrier family 22 member 3 involved_in
acts_upstream_of_or_within 		IEA Ensembl GO_REF:0000107 NCBI chr 6:158,240,390...158,344,338
Ensembl chr 6:163,247,643...163,349,735 		JBrowse link
G SLC29A4 solute carrier family 29 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:5,538,436...5,559,506
Ensembl chr 7:5,560,565...5,575,637 		JBrowse link
negative regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600 		JBrowse link
negative regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPM6B glycoprotein M6B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:6,377,913...6,544,826
Ensembl chr  X:13,666,192...13,711,964 		JBrowse link
G NOS1 nitric oxide synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005 		JBrowse link
G SLC18A1 solute carrier family 18 member A1 ISO G-protein mediated uptake inhibition RGD PMID:16926160 RGD:5130998 NCBI chr 8:19,369,843...19,408,412
Ensembl chr 8:16,318,744...16,353,708 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600 		JBrowse link
neurotransmitter reuptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC1A2 solute carrier family 1 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:35,223,811...35,392,799
Ensembl chr11:35,107,920...35,265,878 		JBrowse link
G SLC6A1 solute carrier family 6 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,930,455...10,976,968
Ensembl chr 3:11,296,023...11,323,624 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:35,885,756...35,935,638
Ensembl chr16:54,990,773...55,040,504 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:26,546,177...26,572,301
Ensembl chr17:27,050,900...27,092,882 		JBrowse link
G SLC6A5 solute carrier family 6 member 5 involved_in ISO (PMID:23486948) SynGO PMID:23486948 NCBI chr11:20,627,557...20,691,347
Ensembl chr11:20,538,054...20,592,893 		JBrowse link
positive regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G NAT8L N-acetyltransferase 8 like involved_in ISO (PMID:19014384) UniProt PMID:19014384 NCBI chr 4:2,201,326...2,211,302 JBrowse link
G RAB3B RAB3B, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:51,170,956...51,242,828
Ensembl chr 1:52,666,713...52,723,975 		JBrowse link
positive regulation of glutamate uptake involved in transmission of nerve impulse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB1 integrin subunit beta 1 acts_upstream_of_or_within ISO (PMID:25716834) ARUK-UCL PMID:25716834 NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031 		JBrowse link
G SLC17A8 solute carrier family 17 member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:97,935,177...98,001,240
Ensembl chr12:101,342,113...101,405,844 		JBrowse link
positive regulation of neurotransmitter uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G GDNF glial cell derived neurotrophic factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:72,539,374...72,566,918
Ensembl chr 5:77,577,313...77,601,362 		JBrowse link
G TOR1A torsin family 1 member A involved_in ISO (PMID:15505207) UniProt PMID:15505207 NCBI chr 9:100,940,554...100,951,726 JBrowse link
regulation of glutamate uptake involved in transmission of nerve impulse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PER2 period circadian regulator 2 involved_in ISO (PMID:16595674) UniProt PMID:16595674 NCBI chr2B:125,477,021...125,521,577
Ensembl chr2B:244,328,122...244,371,040 		JBrowse link
regulation of neurotransmitter uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in ISO (PMID:19118188) ARUK-UCL PMID:19118188 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G ARL6IP5 ARF like GTPase 6 interacting protein 5 involved_in ISO PMID:11242046 SynGO PMID:11242046 RGD:1299537 NCBI chr 3:69,020,908...69,042,065
Ensembl chr 3:70,387,581...70,408,909 		JBrowse link
G DRD2 dopamine receptor D2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G DRD3 dopamine receptor D3 involved_in ISO (PMID:27393374) SynGO PMID:27393374 NCBI chr 3:111,265,834...111,317,176
Ensembl chr 3:118,187,636...118,237,403 		JBrowse link
G FLOT1 flotillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,472,839...30,487,809
Ensembl chr 6:31,342,033...31,357,559 		JBrowse link
G GFAP glial fibrillary acidic protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:12,407,211...12,417,072
Ensembl chr17:12,579,754...12,591,961 		JBrowse link
G SYNGR3 synaptogyrin 3 involved_in ISO PMID:19357284 SynGO PMID:19357284 RGD:13702442 NCBI chr16:710,090...714,421
Ensembl chr16:2,078,645...2,083,100 		JBrowse link
regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB3 integrin subunit beta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:10,134,450...10,194,596
Ensembl chr17:10,353,111...10,392,382 		JBrowse link
serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC18A1 solute carrier family 18 member A1 involved_in ISO
IEA 		RGD
GOC
Ensembl		 PMID:19008227 GO_REF:0000107 GO_REF:0000108 RGD:5131091 NCBI chr 8:19,369,843...19,408,412
Ensembl chr 8:16,318,744...16,353,708 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 involved_in ISO
IEA 		RGD
Ensembl		 PMID:20007701 GO_REF:0000107 RGD:5130957 NCBI chr10:113,823,005...113,862,451
Ensembl chr10:117,250,639...117,290,064 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:44,630,006...44,632,419 JBrowse link
G SLC18B1 solute carrier family 18 member B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:130,547,192...130,576,466
Ensembl chr 6:134,654,489...134,683,182 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:158,004,545...158,046,428
Ensembl chr 6:163,014,663...163,054,681 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:158,058,226...158,150,917
Ensembl chr 6:163,065,317...163,158,931 		JBrowse link
G SLC22A3 solute carrier family 22 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:158,240,390...158,344,338
Ensembl chr 6:163,247,643...163,349,735 		JBrowse link
G SLC29A4 solute carrier family 29 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:5,538,436...5,559,506
Ensembl chr 7:5,560,565...5,575,637 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 involved_in ISO
IEA 		RGD
TreeGrafter
Ensembl		 PMID:12944413 GO_REF:0000107 GO_REF:0000118 RGD:1580638 NCBI chr17:26,546,177...26,572,301
Ensembl chr17:27,050,900...27,092,882 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    localization 5852
      establishment of localization 5199
        transport 4294
          import into cell 921
            neurotransmitter uptake 45
              histamine uptake + 4
              negative regulation of neurotransmitter uptake + 4
              neurotransmitter reuptake + 29
              positive regulation of neurotransmitter uptake + 6
              regulation of neurotransmitter uptake + 20
paths to the root