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ONTOLOGY REPORT - ANNOTATIONS


Term:neurotransmitter uptake
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Accession:GO:0001504 term browser browse the term
Definition:The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
Synonyms:exact_synonym: neurotransmitter import
 narrow_synonym: neurotransmitter import into glial cell;   neurotransmitter import into neuron
 broad_synonym: neurotransmitter recycling



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neurotransmitter uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 acts_upstream_of_or_within ISO MGI:2664907 (MGI:2664023|PMID:12805306) RGD PMID:12805306 MGI:2664023 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Slc17a6 solute carrier family 17 member 6 acts_upstream_of_or_within TAS
ISO
(MGI:2150836|PMID:11432869) RGD PMID:11432869 PMID:11551935 MGI:2150836, RGD:628484 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
JBrowse link
G Slc1a6 solute carrier family 1 member 6 involved_in ISO (PMID:7791878) RGD PMID:7791878 NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449
JBrowse link
G Slc1a7 solute carrier family 1 member 7 involved_in ISO (PMID:9108121) RGD PMID:9108121 NCBI chr 5:122,731,003...122,775,139
Ensembl chr 5:122,731,003...122,775,134
JBrowse link
G Slc29a1 solute carrier family 29 member 1 involved_in ISO (MGI:5902903|PMID:28069792) RGD PMID:28069792 MGI:5902903 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
JBrowse link
G Slc29a2 solute carrier family 29 member 2 involved_in ISO UniProtKB:Q9JIM1 (MGI:5902903|PMID:28069792) RGD PMID:28069792 MGI:5902903 NCBI chr 1:202,327,641...202,335,185
Ensembl chr 1:202,327,354...202,335,171
JBrowse link
G Slc6a11 solute carrier family 6 member 11 involved_in ISO (MGI:52213|PMID:8420981) RGD PMID:8420981 MGI:52213 NCBI chr 4:147,297,972...147,413,319
Ensembl chr 4:147,297,969...147,413,443
JBrowse link
G Slc6a3 solute carrier family 6 member 3 involved_in ISO (MGI:78831|PMID:8628395) RGD PMID:8628395 MGI:78831 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slc6a5 solute carrier family 6 member 5 involved_in IMP PMID:8226790 SynGO PMID:8226790 RGD:730010 NCBI chr 1:99,645,389...99,697,016
Ensembl chr 1:99,645,389...99,697,010
JBrowse link
G Slc6a9 solute carrier family 6 member 9 involved_in ISO (MGI:49905|PMID:1618338) RGD PMID:1618338 MGI:49905 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b TAS RGD PMID:7681585 RGD:634183 NCBI chr 1:128,978,471...129,152,479
Ensembl chr 1:128,978,473...129,152,479
JBrowse link
G Syngr3 synaptogyrin 3 involved_in IMP PMID:19357284 SynGO PMID:19357284 RGD:13702442 NCBI chr10:13,710,553...13,715,312
Ensembl chr10:13,704,998...13,715,669
JBrowse link
dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO MGI:3579140 (MGI:3578474|PMID:15721235) RGD PMID:15721235 MGI:3578474 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:2678247 (MGI:2675710|PMID:12915482) RGD PMID:12915482 MGI:2675710 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Slc6a2 solute carrier family 6 member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
JBrowse link
G Slc6a3 solute carrier family 6 member 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
glutamate reuptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln8 CLN8, transmembrane ER and ERGIC protein acts_upstream_of_or_within ISO MGI:1856959 (MGI:1202659|PMID:9600674), (MGI:52690|PMID:8095977) RGD PMID:8095977 PMID:9600674 MGI:1202659 MGI:52690 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3655847|MGI:3761690 (MGI:3760488|PMID:17942730)
Ensembl
RGD
PMID:17942730 GO_REF:0000107 MGI:3760488 NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461
JBrowse link
histamine uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:9687576)
Ensembl
RGD
PMID:9687576 GO_REF:0000107 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a3 solute carrier family 22 member 3 involved_in
acts_upstream_of_or_within
ISO (PMID:20858707), (PMID:23505051)
MGI:2388117 (MGI:3588796|PMID:16061728)
RGD PMID:16061728 PMID:20858707 PMID:23505051 MGI:3588796 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc29a4 solute carrier family 29 member 4 involved_in ISO (PMID:20858707), (PMID:23505051) RGD PMID:20858707 PMID:23505051 NCBI chr12:11,853,540...11,884,660
Ensembl chr12:11,853,540...11,874,834
JBrowse link
negative regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha involved_in ISO (PMID:12958153) RGD PMID:12958153 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
negative regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpm6b glycoprotein m6b involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:5426133|PMID:18581270)
PMID:21873635
UniProt
RGD
PMID:18581270 PMID:21873635 GO_REF:0000024 MGI:5426133, RGD:13792537 NCBI chr  X:28,057,788...28,204,409
Ensembl chr  X:28,059,450...28,204,211
JBrowse link
G Nos1 nitric oxide synthase 1 involved_in ISO (MGI:3710710|PMID:17452640) RGD PMID:17452640 MGI:3710710 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Slc18a1 solute carrier family 18 member A1 IMP G-protein mediated uptake inhibition RGD PMID:16926160 RGD:5130998 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051
JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:16882008) RGD PMID:16882008 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
neurotransmitter reuptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc1a2 solute carrier family 1 member 2 involved_in ISO (MGI:5641112|PMID:25834045) RGD PMID:25834045 MGI:5641112 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc1a7 solute carrier family 1 member 7 involved_in ISO (PMID:9108121) RGD PMID:9108121 NCBI chr 5:122,731,003...122,775,139
Ensembl chr 5:122,731,003...122,775,134
JBrowse link
G Slc29a1 solute carrier family 29 member 1 involved_in ISO (PMID:8986748) RGD PMID:8986748 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
JBrowse link
G Slc29a2 solute carrier family 29 member 2 involved_in ISO (PMID:9396714) RGD PMID:9396714 NCBI chr 1:202,327,641...202,335,185
Ensembl chr 1:202,327,354...202,335,171
JBrowse link
G Slc6a1 solute carrier family 6 member 1 involved_in IMP PMID:1975955 SynGO PMID:1975955 RGD:632739 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293
JBrowse link
G Slc6a11 solute carrier family 6 member 11 involved_in IMP PMID:1400419 SynGO PMID:1400419 RGD:727560 NCBI chr 4:147,297,972...147,413,319
Ensembl chr 4:147,297,969...147,413,443
JBrowse link
G Slc6a2 solute carrier family 6 member 2 involved_in ISO (MGI:1355627|PMID:10769386) RGD PMID:10769386 MGI:1355627 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
JBrowse link
G Slc6a4 solute carrier family 6 member 4 involved_in ISO (MGI:85054|PMID:9037532) RGD PMID:9037532 MGI:85054 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Slc6a5 solute carrier family 6 member 5 involved_in ISO (MGI:5912864|PMID:23486948) RGD PMID:23486948 MGI:5912864 NCBI chr 1:99,645,389...99,697,016
Ensembl chr 1:99,645,389...99,697,010
JBrowse link
positive regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO MGI:1857875 (MGI:1328526|PMID:9886065) RGD PMID:9886065 MGI:1328526 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Nat8l N-acetyltransferase 8-like involved_in ISO (MGI:4943664|PMID:19014384) RGD PMID:19014384 MGI:4943664 NCBI chr14:76,756,077...76,762,712
Ensembl chr14:76,756,077...76,763,411
JBrowse link
G Rab3b RAB3B, member RAS oncogene family involved_in ISO (PMID:20007772) RGD PMID:20007772 NCBI chr 5:123,629,562...123,697,410
Ensembl chr 5:123,644,423...123,697,401
JBrowse link
positive regulation of glutamate uptake involved in transmission of nerve impulse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5629870|PMID:25716834)
Ensembl
RGD
PMID:25716834 GO_REF:0000107 MGI:5629870 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
positive regulation of neurotransmitter uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:22314364) RGD PMID:22314364 NCBI chr 1:48,688,651...49,882,520 JBrowse link
regulation of dopamine uptake involved in synaptic transmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO MGI:2388386 (MGI:2387277|PMID:12223553) RGD PMID:12223553 MGI:2387277 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:8493557)
UniProt
Ensembl
RGD
PMID:8493557 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Tor1a torsin family 1, member A involved_in ISO
ISS
(PMID:15505207)
GO_REF:0000024
RGD
UniProt
PMID:15505207 GO_REF:0000024 NCBI chr 3:14,250,667...14,257,704
Ensembl chr 3:14,250,676...14,257,691
JBrowse link
regulation of glutamate uptake involved in transmission of nerve impulse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Per2 period circadian regulator 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3687603|PMID:16595674)
UniProt
RGD
PMID:16595674 GO_REF:0000024 MGI:3687603 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
regulation of neurotransmitter uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 involved_in IMP PMID:11242046 SynGO PMID:11242046 RGD:1299537 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608
JBrowse link
G Drd2 dopamine receptor D2 involved_in ISO (MGI:2387277|PMID:12223553) RGD PMID:12223553 MGI:2387277 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 involved_in ISO (MGI:6189384|PMID:27393374) RGD PMID:27393374 MGI:6189384 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Flot1 flotillin 1 involved_in ISO (PMID:21399631) RGD PMID:21399631 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
JBrowse link
G Gfap glial fibrillary acidic protein acts_upstream_of_or_within ISO MGI:1857176 (MGI:3046158|PMID:15135219) RGD PMID:15135219 MGI:3046158 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:6101340|PMID:29038237)
UniProt
RGD
PMID:29038237 GO_REF:0000024 MGI:6101340 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a1 solute carrier family 18 member A1 IDA RGD PMID:19008227 RGD:5131091 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051
JBrowse link
G Slc18a2 solute carrier family 18 member A2 IMP RGD PMID:20007701 RGD:5130957 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc22a1 solute carrier family 22 member 1 involved_in ISO (PMID:24688079) RGD PMID:24688079 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a2 solute carrier family 22 member 2 involved_in ISO
IEA
(PMID:9687576)
GO_REF:0000107
RGD
Ensembl
PMID:9687576 GO_REF:0000107 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a3 solute carrier family 22 member 3 involved_in ISO (PMID:20858707) RGD PMID:20858707 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc29a4 solute carrier family 29 member 4 involved_in ISO (PMID:20858707)
(MGI:5484979|PMID:23255610), (MGI:6436398|PMID:20858707)
RGD PMID:20858707 PMID:23255610 MGI:5484979 MGI:6436398 NCBI chr12:11,853,540...11,884,660
Ensembl chr12:11,853,540...11,874,834
JBrowse link
G Slc6a4 solute carrier family 6 member 4 involved_in IMP
ISO
IDA
IBA
(MGI:2178281|PMID:9547354), (MGI:3710710|PMID:17452640), (MGI:6436398|PMID:20858707)
PMID:15627510
PMID:10716733
PMID:14642278
(PMID:16870614), (PMID:17506858), (PMID:7681602), (PMID:8987735)
PMID:21873635
RGD PMID:7681602 PMID:8987735 PMID:9547354 PMID:16870614 PMID:17452640 More... MGI:2178281 MGI:3710710 MGI:6436398, RGD:1580638, RGD:8553308, RGD:8554226, RGD:8553687, RGD:13792537 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    biological regulation 13606
      regulation of biological quality 4205
        regulation of neurotransmitter levels 277
          neurotransmitter uptake 41
            histamine uptake + 3
            negative regulation of neurotransmitter uptake + 4
            neurotransmitter reuptake + 31
            positive regulation of neurotransmitter uptake + 5
            regulation of neurotransmitter uptake + 17
Path 2
Term Annotations click to browse term
  biological_process 19497
    localization 6488
      establishment of localization 4887
        transport 4725
          neurotransmitter transport 264
            neurotransmitter uptake 41
              histamine uptake + 3
              negative regulation of neurotransmitter uptake + 4
              neurotransmitter reuptake + 31
              positive regulation of neurotransmitter uptake + 5
              regulation of neurotransmitter uptake + 17
paths to the root