Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:Prp19 complex
go back to main search page
Accession:GO:0000974 term browser browse the term
Definition:A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.
Synonyms:narrow_synonym: Prp19/CDC5 complex;   nineteen complex
 related_synonym: NTC


show annotations for term's descendants           Sort by:
 
Prp19 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcas2 BCAS2, pre-mRNA processing factor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:205,662,633...205,670,514
Ensembl chr 2:205,662,588...205,670,511
JBrowse link
G Cdc5l cell division cycle 5-like ISO
ISS
(PMID:20176811)
GO_REF:0000024
RGD
UniProt
PMID:20176811 GO_REF:0000024 NCBI chr 9:17,949,764...17,988,514
Ensembl chr 9:17,949,764...17,988,509
JBrowse link
G Crnkl1 crooked neck pre-mRNA splicing factor 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:18,349,226...18,351,540
Ensembl chr 6:18,349,167...18,351,536
JBrowse link
G Ctnnbl1 catenin, beta like 1 ISO
ISS
(PMID:15175653)
GO_REF:0000024
RGD
UniProt
PMID:15175653 GO_REF:0000024 NCBI chr 3:154,212,245...154,373,170
Ensembl chr 3:154,212,202...154,373,169
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO
ISS
(PMID:20176811)
GO_REF:0000024
RGD
UniProt
PMID:20176811 GO_REF:0000024 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Isy1 ISY1 splicing factor homolog IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:119,721,659...119,742,349
Ensembl chr 4:119,721,660...119,742,349
JBrowse link
G LOC102548514 crooked neck-like protein 1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:140,125,232...140,141,730
Ensembl chr 3:140,126,797...140,141,679
JBrowse link
G Plrg1 pleiotropic regulator 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:182,040,338...182,056,669
Ensembl chr 2:182,040,318...182,056,673
JBrowse link
G Polr2a RNA polymerase II subunit A colocalizes_with ISO (PMID:21536736) RGD PMID:21536736 NCBI chr10:56,339,277...56,364,888
Ensembl chr10:56,339,284...56,365,084
JBrowse link
G Prpf19 pre-mRNA processing factor 19 ISO
IBA
ISS
(PMID:20176811)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:20176811, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:226,947,065...226,958,147
Ensembl chr 1:226,947,105...226,958,144
JBrowse link
G Rbm22 RNA binding motif protein 22 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:55,828,158...55,839,421
Ensembl chr18:55,828,158...55,838,966
JBrowse link
G Syf2 SYF2 pre-mRNA-splicing factor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:153,269,638...153,277,562
Ensembl chr 5:153,269,526...153,277,563
JBrowse link
G U2af2 U2 small nuclear RNA auxiliary factor 2 colocalizes_with ISO (PMID:21536736) RGD PMID:21536736 NCBI chr 1:72,312,260...72,329,828
Ensembl chr 1:72,312,727...72,329,856
JBrowse link
G Xab2 XPA binding protein 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:2,158,391...2,170,397
Ensembl chr12:2,158,389...2,170,504
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6092
      Prp19 complex 14
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.