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ONTOLOGY REPORT - ANNOTATIONS


Term:outer kinetochore
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Accession:GO:0000940 term browser browse the term
Definition:The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
Synonyms:exact_synonym: condensed chromosome outer kinetochore;   condensed nuclear chromosome outer kinetochore;   outer kinetochore of condensed chromosome;   outer kinetochore of condensed nuclear chromosome
 narrow_synonym: outer kinetochore plate
 alt_id: GO:0000942



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outer kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bod1 biorientation of chromosomes in cell division 1 part_of ISO (PMID:17938248) RGD PMID:17938248 NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase part_of ISO (PMID:22331848) RGD PMID:22331848 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B part_of ISO (PMID:19468067), (PMID:22331848)
(PMID:14519686), (PMID:19283064)
RGD PMID:14519686 PMID:19283064 PMID:19468067 PMID:22331848 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Ccnb1 cyclin B1 part_of ISO
IEA
(PMID:18195732)
GO_REF:0000107
RGD
Ensembl
PMID:18195732 GO_REF:0000107 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cenpe centromere protein E part_of ISO (PMID:19283064) RGD PMID:19283064 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cenpf centromere protein F part_of ISO (PMID:7542657), (PMID:7642639), (PMID:7904902) RGD PMID:7542657 PMID:7642639 PMID:7904902 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Crebbp CREB binding protein part_of ISO (PMID:14519686) RGD PMID:14519686 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Dsn1 DSN1 component of MIS12 kinetochore complex part_of ISO (PMID:24530301) RGD PMID:24530301 NCBI chr 3:145,652,741...145,668,025
Ensembl chr 3:145,652,737...145,665,856
JBrowse link
G Knl1 kinetochore scaffold 1 part_of ISO (PMID:24530301) RGD PMID:24530301 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
G LOC108352183 spindle and kinetochore-associated protein 2 pseudogene part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:67,932,790...67,950,325
Ensembl chr10:67,949,696...67,950,097
Ensembl chr10:67,949,696...67,950,097
JBrowse link
G Mis12 MIS12 kinetochore complex component part_of ISO (PMID:24530301) RGD PMID:24530301 NCBI chr10:55,739,741...55,747,915
Ensembl chr10:55,739,564...55,751,068
JBrowse link
G Ndc80 NDC80 kinetochore complex component part_of ISO (PMID:18195732), (PMID:24530301) RGD PMID:18195732 PMID:24530301 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Nsl1 NSL1 component of MIS12 kinetochore complex part_of ISO (PMID:24530301) RGD PMID:24530301 NCBI chr13:102,649,050...102,674,059
Ensembl chr13:102,649,058...102,674,054
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex part_of ISO (PMID:24530301) RGD PMID:24530301 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Plk1 polo-like kinase 1 part_of IEA
ISO
GO_REF:0000107
(PMID:18195732)
Ensembl
RGD
PMID:18195732 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Pmf1 polyamine-modulated factor 1 part_of ISO (PMID:24530301) RGD PMID:24530301 NCBI chr 2:173,848,074...173,868,272
Ensembl chr 2:173,848,074...173,868,270
JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 part_of ISS
ISO
IBA
GO_REF:0000024
(PMID:17093495), (PMID:19289083), (PMID:26981768), (PMID:28479321)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:17093495 PMID:19289083 PMID:26981768 PMID:28479321 GO_REF:0000024 GO_REF:0000033 NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037
JBrowse link
G Ska2 spindle and kinetochore associated complex subunit 2 part_of ISS
ISO
IBA
GO_REF:0000024
(PMID:17093495), (PMID:19289083), (PMID:28479321)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:17093495 PMID:19289083 PMID:28479321 GO_REF:0000024 GO_REF:0000033 NCBI chr10:71,921,474...71,939,461
Ensembl chr10:71,921,582...71,939,458
JBrowse link
G Ska2l1 spindle and kinetochore associated complex subunit 2 like 1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:184,226,732...184,300,750
Ensembl chr 1:184,215,516...184,300,008
JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 part_of ISS
ISO
IBA
IEA
GO_REF:0000024
(PMID:19289083), (PMID:19646878), (PMID:28479321)
GO_REF:0000033
GO_REF:0000002
UniProt
RGD
GO_Central
InterPro
PMID:19289083 PMID:19646878 PMID:28479321 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr15:31,951,812...31,971,010
Ensembl chr15:31,951,825...31,971,010
JBrowse link
G Spc24 SPC24 component of NDC80 kinetochore complex part_of ISO (PMID:24530301) RGD PMID:24530301 NCBI chr 8:20,300,315...20,305,354
Ensembl chr 8:20,300,319...20,305,310
JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex part_of ISO (PMID:24530301) RGD PMID:24530301 NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 part_of ISO
IBA
ISS
(PMID:19468067)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:19468067 GO_REF:0000024 GO_REF:0000033 NCBI chr10:19,269,125...19,294,213
Ensembl chr10:19,269,127...19,294,127
JBrowse link
G Zwint ZW10 interacting kinetochore protein part_of ISO (PMID:24530301) RGD PMID:24530301 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
JBrowse link
Knl1/Spc105 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Knl1 kinetochore scaffold 1 part_of ISO (PMID:27881301) RGD PMID:27881301 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
G Zwint ZW10 interacting kinetochore protein part_of ISO
ISS
(PMID:27881301)
GO_REF:0000024
RGD
UniProt
PMID:27881301 GO_REF:0000024 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
JBrowse link
MIS12/MIND type complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsn1 DSN1 component of MIS12 kinetochore complex part_of ISO
IBA
(PMID:16585270), (PMID:20819937), (PMID:27881301)
GO_REF:0000033
RGD
GO_Central
PMID:16585270 PMID:20819937 PMID:27881301 GO_REF:0000033 NCBI chr 3:145,652,741...145,668,025
Ensembl chr 3:145,652,737...145,665,856
JBrowse link
G Mis12 MIS12 kinetochore complex component part_of IEA
IBA
ISS
ISO
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024
(PMID:16585270), (PMID:20819937), (PMID:27881301)
Ensembl
GO_Central
UniProt
RGD
PMID:16585270 PMID:20819937 PMID:27881301 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:55,739,741...55,747,915
Ensembl chr10:55,739,564...55,751,068
JBrowse link
G Nsl1 NSL1 component of MIS12 kinetochore complex part_of ISO
IBA
(PMID:16585270), (PMID:20819937), (PMID:27881301)
GO_REF:0000033
RGD
GO_Central
PMID:16585270 PMID:20819937 PMID:27881301 GO_REF:0000033 NCBI chr13:102,649,050...102,674,059
Ensembl chr13:102,649,058...102,674,054
JBrowse link
G Pmf1 polyamine-modulated factor 1 part_of ISO
IBA
(PMID:16585270), (PMID:20819937), (PMID:27881301)
GO_REF:0000033
RGD
GO_Central
PMID:16585270 PMID:20819937 PMID:27881301 GO_REF:0000033 NCBI chr 2:173,848,074...173,868,272
Ensembl chr 2:173,848,074...173,868,270
JBrowse link
Ndc80 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ndc80 NDC80 kinetochore complex component part_of IBA
ISO
GO_REF:0000033
(PMID:14699129), (PMID:18455984), (PMID:20819937)
GO_Central
RGD
PMID:14699129 PMID:18455984 PMID:20819937 GO_REF:0000033 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex part_of ISS
ISO
IBA
IEA
GO_REF:0000024
(PMID:14699129), (PMID:18455984), (PMID:20819937)
GO_REF:0000033
GO_REF:0000002
UniProt
RGD
GO_Central
InterPro
PMID:14699129 PMID:18455984 PMID:20819937 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Spc24 SPC24 component of NDC80 kinetochore complex part_of IBA
ISO
GO_REF:0000033
(PMID:14699129), (PMID:18455984), (PMID:20819937)
GO_Central
RGD
PMID:14699129 PMID:18455984 PMID:20819937 GO_REF:0000033 NCBI chr 8:20,300,315...20,305,354
Ensembl chr 8:20,300,319...20,305,310
JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex part_of ISS
ISO
IBA
GO_REF:0000024
(PMID:14699129), (PMID:18455984), (PMID:20819937)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:14699129 PMID:18455984 PMID:20819937 GO_REF:0000024 GO_REF:0000033 NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
JBrowse link
SKA complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ska1 spindle and kinetochore associated complex subunit 1 part_of ISO
IEA
(PMID:31804178)
GO_REF:0000107
RGD
Ensembl
PMID:31804178 GO_REF:0000107 NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037
JBrowse link
G Ska2 spindle and kinetochore associated complex subunit 2 part_of ISO (PMID:31804178) RGD PMID:31804178 NCBI chr10:71,921,474...71,939,461
Ensembl chr10:71,921,582...71,939,458
JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 part_of ISO
IEA
(PMID:31804178)
GO_REF:0000107
RGD
Ensembl
PMID:31804178 GO_REF:0000107 NCBI chr15:31,951,812...31,971,010
Ensembl chr15:31,951,825...31,971,010
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20813
    protein-containing complex 6433
      outer kinetochore 24
        DASH complex 0
        Knl1/Spc105 complex 2
        MIS12/MIND type complex 4
        Ndc80 complex 4
        SKA complex 3
Path 2
Term Annotations click to browse term
  cellular_component 20813
    cellular anatomical entity 20576
      organelle 14001
        non-membrane-bounded organelle 5255
          intracellular non-membrane-bounded organelle 5255
            chromosome 1385
              chromosomal region 334
                chromosome, centromeric region 234
                  condensed chromosome, centromeric region 166
                    kinetochore 154
                      outer kinetochore 24
                        DASH complex 0
                        Knl1/Spc105 complex 2
                        MIS12/MIND type complex 4
                        Ndc80 complex 4
                        SKA complex 3
paths to the root