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ONTOLOGY REPORT - ANNOTATIONS


Term:mRNA regulatory element binding translation repressor activity
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Accession:GO:0000900 term browser browse the term
Definition:Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
Synonyms:broad_synonym: translation repressor activity, nucleic acid binding



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mRNA regulatory element binding translation repressor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 enables ISS
ISO
IEA
IBA
GO_REF:0000024
(MGI:5543770|PMID:18752464)
GO_REF:0000118
GO_REF:0000033
UniProt
RGD
TreeGrafter
GO_Central
PMID:18752464 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:5543770 NCBI chr 1:135,300,048...135,407,688
Ensembl chr 1:135,300,461...135,409,760
JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 enables IDA
ISO
IBA
PMID:22157746
(MGI:5543770|PMID:18752464)
GO_REF:0000033
RGD
GO_Central
PMID:18752464 PMID:22157746 GO_REF:0000033 MGI:5543770, RGD:8553654 NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743
JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 enables ISO
IBA
(MGI:5314154|PMID:22157746)
GO_REF:0000033
RGD
GO_Central
PMID:22157746 GO_REF:0000033 MGI:5314154 NCBI chr 1:234,749,138...234,931,219
Ensembl chr 1:234,751,733...234,931,560
JBrowse link
G Cpeb4 cytoplasmic polyadenylation element binding protein 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603
JBrowse link
G Dhfr dihydrofolate reductase enables ISO (PMID:8490020) RGD PMID:8490020 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Paip2 poly(A) binding protein interacting protein 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:27,199,762...27,218,359
Ensembl chr18:27,199,796...27,214,863
JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B enables ISO (PMID:16804161) RGD PMID:16804161 NCBI chr 4:116,292,001...116,323,387
Ensembl chr 4:116,292,020...116,323,379
JBrowse link
G Pura purine rich element binding protein A enables ISO (MGI:3688338|PMID:12933792) RGD PMID:12933792 MGI:3688338 NCBI chr18:27,885,071...27,905,509
Ensembl chr18:27,884,556...27,905,513
JBrowse link
G Purb purine rich element binding protein B enables IDA PMID:12933792 HGNC-UCL PMID:12933792 RGD:1581942 NCBI chr14:81,342,374...81,344,857
Ensembl chr14:81,336,448...81,351,432
JBrowse link
G Rara retinoic acid receptor, alpha IDA RGD PMID:19073915 RGD:2314253 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 enables ISO (PMID:10995219) RGD PMID:10995219 NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Tyms thymidylate synthetase enables ISO (PMID:1924359) RGD PMID:1924359 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20893
    translation regulator activity 347
      translation repressor activity 222
        mRNA regulatory element binding translation repressor activity 12
Path 2
Term Annotations click to browse term
  molecular_function 20893
    binding 17956
      organic cyclic compound binding 6324
        nucleic acid binding 4050
          translation regulator activity, nucleic acid binding 123
            mRNA regulatory element binding translation repressor activity 12
paths to the root