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ONTOLOGY REPORT - ANNOTATIONS

Term:Hrd1p ubiquitin ligase complex
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Accession:GO:0000836 term browser browse the term
Definition:A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).
Synonyms:related_synonym: HRD1 ubiquitin ligase complex


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Hrd1p ubiquitin ligase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam8a1 family with sequence similarity 8, member A1 part_of ISO (PMID:28827405) RGD PMID:28827405 NCBI chr17:18,026,601...18,035,509
Ensembl chr17:18,026,601...18,035,470 		JBrowse link
Hrd1p ubiquitin ligase ERAD-L complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Derl1 derlin 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145 		JBrowse link
G Derl2 derlin 2 part_of IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:55,727,764...55,739,442
Ensembl chr10:55,727,643...55,739,518 		JBrowse link
G Derl3 derlin 3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027 		JBrowse link
G ENSRNOG00000066502 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 9:2,759,881...2,760,635 JBrowse link
G ENSRNOG00000069918 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 9:2,654,884...2,655,638 JBrowse link
G ENSRNOG00000070059 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 9:2,698,519...2,699,273 JBrowse link
G ENSRNOG00000070668 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 9:3,071,123...3,071,876 JBrowse link
G Sel1l SEL1L adaptor subunit of SYVN1 ubiquitin ligase part_of ISO
ISS
IEA		 (PMID:26471130)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:26471130 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:110,735,450...110,779,695
Ensembl chr 6:110,735,450...110,779,648 		JBrowse link
G Syvn1 synoviolin 1 part_of ISO (PMID:26471130), (PMID:28827405) RGD PMID:26471130 PMID:28827405 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      endoplasmic reticulum protein-containing complex 152
        ER ubiquitin ligase complex 10
          Hrd1p ubiquitin ligase complex 10
            Hrd1p ubiquitin ligase ERAD-L complex 9
            Hrd1p ubiquitin ligase ERAD-M complex 0
Path 2
Term Annotations click to browse term
  cellular_component 21392
    cellular anatomical entity 21234
      organelle 14344
        intracellular organelle 13898
          intracellular membrane-bounded organelle 12331
            endoplasmic reticulum 1933
              endoplasmic reticulum subcompartment 1080
                endoplasmic reticulum membrane 1070
                  ER ubiquitin ligase complex 10
                    Hrd1p ubiquitin ligase complex 10
                      Hrd1p ubiquitin ligase ERAD-L complex 9
                      Hrd1p ubiquitin ligase ERAD-M complex 0
paths to the root