Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


Term:inositol heptakisphosphate kinase activity
go back to main search page
Accession:GO:0000829 term browser browse the term
Definition:Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.
Synonyms:xref: reactome:R-HSA-1855157 "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus";   reactome:R-HSA-1855182 "5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol";   reactome:R-HSA-1855194 "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol"

show annotations for term's descendants           Sort by:
inositol heptakisphosphate kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppip5k1 diphosphoinositol pentakisphosphate kinase 1 enables IEA
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 3:108,284,120...108,327,683
Ensembl chr 3:108,284,120...108,323,428
JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:98,315,280...98,394,537
Ensembl chr 9:98,315,252...98,390,814
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20699
    catalytic activity 6088
      transferase activity 2415
        transferase activity, transferring phosphorus-containing groups 1000
          phosphotransferase activity, phosphate group as acceptor 38
            inositol heptakisphosphate kinase activity 2
              inositol heptakisphosphate 4-kinase activity 0
              inositol heptakisphosphate 5-kinase activity 0
              inositol heptakisphosphate 6-kinase activity 0
paths to the root