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ONTOLOGY REPORT - ANNOTATIONS

Term:inositol hexakisphosphate kinase activity
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Accession:GO:0000828 term browser browse the term
Definition:Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.
Synonyms:xref: reactome:R-HSA-1855207 "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus";   reactome:R-HSA-1855216 "IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol";   reactome:R-HSA-1855227 "IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol"


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inositol hexakisphosphate kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ip6k1 inositol hexakisphosphate kinase 1 enables IBA
ISO		 PMID:21873635
(PMID:10574768)		 RGD PMID:10574768 PMID:21873635 RGD:13792537 NCBI chr 8:108,693,068...108,737,278 JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 enables ISO
IBA		 (PMID:10574768)
MGI:5635272 (MGI:5581560|PMID:24657168)
PMID:21873635		 RGD PMID:10574768 PMID:24657168 PMID:21873635 MGI:5581560, RGD:13792537 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166 		JBrowse link
G Ip6k3 inositol hexakisphosphate kinase 3 enables ISO
IBA		 (PMID:11502751)
PMID:21873635		 RGD PMID:11502751 PMID:21873635 RGD:13792537 NCBI chr20:5,223,863...5,245,443
Ensembl chr20:5,224,120...5,245,428 		JBrowse link
G Itpka inositol-trisphosphate 3-kinase A enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004 		JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,500,957...82,522,533
Ensembl chr 1:82,500,957...82,522,779 		JBrowse link
G Ppip5k1 diphosphoinositol pentakisphosphate kinase 1 enables ISO
IBA
IEA
IDA		 (PMID:17690096)
PMID:21873635
GO_REF:0000117
PMID:17702752		 RGD
UniProt		 PMID:17690096 PMID:21873635 PMID:17702752 GO_REF:0000117, RGD:13792537, RGD:151356608 NCBI chr 3:108,284,120...108,327,683
Ensembl chr 3:108,284,120...108,323,428 		JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 enables ISO
IBA		 (MGI:3761985|PMID:17690096)
PMID:21873635
(PMID:17690096)		 RGD PMID:17690096 PMID:21873635 MGI:3761985, RGD:13792537 NCBI chr 9:98,315,280...98,394,537
Ensembl chr 9:98,315,252...98,390,814 		JBrowse link
inositol hexakisphosphate 1-kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ip6k1 inositol hexakisphosphate kinase 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 8:108,693,068...108,737,278 JBrowse link
G Ppip5k1 diphosphoinositol pentakisphosphate kinase 1 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 3:108,284,120...108,327,683
Ensembl chr 3:108,284,120...108,323,428 		JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 9:98,315,280...98,394,537
Ensembl chr 9:98,315,252...98,390,814 		JBrowse link
inositol hexakisphosphate 3-kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ip6k1 inositol hexakisphosphate kinase 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 8:108,693,068...108,737,278 JBrowse link
G Ppip5k1 diphosphoinositol pentakisphosphate kinase 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 3:108,284,120...108,327,683
Ensembl chr 3:108,284,120...108,323,428 		JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 9:98,315,280...98,394,537
Ensembl chr 9:98,315,252...98,390,814 		JBrowse link
inositol hexakisphosphate 5-kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ip6k1 inositol hexakisphosphate kinase 1 enables IEA GO_REF:0000116
GO_REF:0000003		 RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 8:108,693,068...108,737,278 JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 enables ISO
ISS		 (PMID:30624931)
GO_REF:0000024		 RGD
UniProt		 PMID:30624931 GO_REF:0000024 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166 		JBrowse link
G Ppip5k1 diphosphoinositol pentakisphosphate kinase 1 enables IEA
ISO
ISS		 GO_REF:0000003
(PMID:17412958)
GO_REF:0000024		 UniProt
RGD		 PMID:17412958 GO_REF:0000003 GO_REF:0000024 NCBI chr 3:108,284,120...108,327,683
Ensembl chr 3:108,284,120...108,323,428 		JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 9:98,315,280...98,394,537
Ensembl chr 9:98,315,252...98,390,814 		JBrowse link
inositol hexakisphosphate 6-kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ip6k3 inositol hexakisphosphate kinase 3 enables ISO (PMID:11502751) RGD PMID:11502751 NCBI chr20:5,223,863...5,245,443
Ensembl chr20:5,224,120...5,245,428 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20699
    catalytic activity 6088
      transferase activity 2415
        transferase activity, transferring phosphorus-containing groups 1000
          phosphotransferase activity, phosphate group as acceptor 38
            inositol hexakisphosphate kinase activity 8
              inositol hexakisphosphate 1-kinase activity 3
              inositol hexakisphosphate 3-kinase activity 3
              inositol hexakisphosphate 4-kinase activity 0
              inositol hexakisphosphate 5-kinase activity 4
              inositol hexakisphosphate 6-kinase activity 1
paths to the root