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ONTOLOGY REPORT - ANNOTATIONS


Term:nuclear MIS12/MIND complex
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Accession:GO:0000818 term browser browse the term
Definition:A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1.
Synonyms:exact_synonym: MIND complex;   Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex


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  cellular_component 12105
    protein-containing complex 3864
      MIS12/MIND type complex 4
        nuclear MIS12/MIND complex 0
Path 2
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  cellular_component 12105
    cellular anatomical entity 11959
      organelle 9371
        non-membrane-bounded organelle 3325
          intracellular non-membrane-bounded organelle 3303
            chromosome 828
              chromosomal region 239
                chromosome, centromeric region 153
                  condensed chromosome, centromeric region 42
                    condensed chromosome kinetochore 29
                      MIS12/MIND type complex 4
                        nuclear MIS12/MIND complex 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.