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ONTOLOGY REPORT - ANNOTATIONS


Term:nuclear MIS12/MIND complex
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Accession:GO:0000818 term browser browse the term
Definition:A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1.
Synonyms:exact_synonym: MIND complex;   Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex


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nuclear MIS12/MIND complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsn1 DSN1 homolog, MIS12 kinetochore complex component IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:156,995,062...157,007,075
Ensembl chr 2:156,995,265...157,007,154
JBrowse link
G Mis12 MIS12 kinetochore complex component IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr11:71,019,568...71,027,371
Ensembl chr11:71,019,611...71,027,371
JBrowse link
G Pmf1 polyamine-modulated factor 1 IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:88,394,138...88,410,445
Ensembl chr 3:88,394,143...88,410,331
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 23184
    protein-containing complex 5493
      MIS12/MIND type complex 4
        nuclear MIS12/MIND complex 3
Path 2
Term Annotations click to browse term
  cellular_component 23184
    cellular anatomical entity 19097
      organelle 12901
        non-membrane-bounded organelle 4769
          intracellular non-membrane-bounded organelle 4751
            chromosome 1598
              chromosomal region 304
                chromosome, centromeric region 204
                  condensed chromosome, centromeric region 57
                    condensed chromosome kinetochore 37
                      MIS12/MIND type complex 4
                        nuclear MIS12/MIND complex 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.