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ONTOLOGY REPORT - ANNOTATIONS

Term:ESCRT III complex
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Accession:GO:0000815 term browser browse the term
Definition:A complex with membrane scission activity that plays a major role in many processes where membranes are remodelled - including endosomal transport (vesicle budding), nuclear envelope organisation (membrane closure, mitotic bridge cleavage), and cytokinesis (abscission).
Synonyms:broad_synonym: Endosomal Sorting Complex Required for Transport

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ESCRT III complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp1b charged multivesicular body protein 1B part_of ISO (PMID:24878737) UniProt PMID:24878737 NCBI chrNW_004955402:1,196,912...1,199,480 JBrowse link
G Chmp2a charged multivesicular body protein 2A part_of ISO (PMID:18687924), (PMID:26040712) UniProt PMID:18687924 PMID:26040712 NCBI chrNW_004955584:1,156,828...1,160,056
Ensembl chrNW_004955584:1,156,828...1,160,056 		JBrowse link
G Chmp2b charged multivesicular body protein 2B part_of ISO (PMID:24878737) UniProt PMID:24878737 NCBI chrNW_004955407:6,014,478...6,047,916
Ensembl chrNW_004955407:6,014,478...6,047,916 		JBrowse link
G Chmp4b charged multivesicular body protein 4B part_of ISO (PMID:18209100), (PMID:21310966), (PMID:21975012), (PMID:24878737), (PMID:26040712) UniProt PMID:18209100 PMID:21310966 PMID:21975012 PMID:24878737 PMID:26040712 NCBI chrNW_004955422:27,482,239...27,526,798
Ensembl chrNW_004955422:27,478,698...27,526,575 		JBrowse link
G Chmp6 charged multivesicular body protein 6 part_of ISO (PMID:24878737) UniProt PMID:24878737 NCBI chrNW_004955506:1,987,710...1,994,731
Ensembl chrNW_004955506:1,987,195...1,994,666 		JBrowse link
G Chmp7 charged multivesicular body protein 7 part_of ISO (PMID:16856878), (PMID:26040712) UniProt PMID:16856878 PMID:26040712 NCBI chrNW_004955403:46,467,463...46,478,897
Ensembl chrNW_004955403:46,467,463...46,478,897 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12554
    protein-containing complex 4416
      membrane protein complex 879
        ESCRT III complex 6
Path 2
Term Annotations click to browse term
  cellular_component 12554
    cellular anatomical entity 12397
      organelle 9788
        intracellular organelle 9421
          intracellular membrane-bounded organelle 8477
            intracellular vesicle 1494
              cytoplasmic vesicle 1488
                cytoplasmic vesicle membrane 564
                  endosome membrane 274
                    ESCRT III complex 6
paths to the root