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ONTOLOGY REPORT - ANNOTATIONS

Term:adenyl-nucleotide exchange factor activity
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Accession:GO:0000774 term browser browse the term
Definition:Binds to and stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.
Synonyms:xref: reactome:R-HSA-5252079 "HSP110s exchange ATP for ADP on HSP70s:ADP"


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adenyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag1 BAG cochaperone 1 enables ISO
IEA
IBA
ISS		 (PMID:24318877)
GO_REF:0000107
PMID:21873635
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:24318877 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075 		JBrowse link
G Bag2 BAG cochaperone 2 enables IBA
ISO		 PMID:21873635
(PMID:24318877)		 RGD PMID:24318877 PMID:21873635 RGD:13792537 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721 		JBrowse link
G Bag3 BAG cochaperone 3 enables IBA
ISO		 PMID:21873635
(PMID:20060297), (PMID:24318877)		 RGD PMID:20060297 PMID:24318877 PMID:21873635 RGD:13792537 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bag5 BAG cochaperone 5 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Grpel1 GrpE-like 1, mitochondrial enables IBA
IEA		 PMID:21873635
GO_REF:0000002		 InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200 		JBrowse link
G Grpel2 GrpE-like 2, mitochondrial enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:55,167,831...55,180,073
Ensembl chr18:55,168,209...55,180,180 		JBrowse link
G Hspbp1 HSPA (Hsp70) binding protein 1 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:69,165,394...69,189,062
Ensembl chr 1:69,165,572...69,244,593 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 enables ISO
ISS		 (PMID:24318877)
GO_REF:0000024		 RGD
UniProt		 PMID:24318877 GO_REF:0000024 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Pfn1 profilin 1 enables ISO (PMID:7758455) RGD PMID:7758455 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Sil1 SIL1 nucleotide exchange factor enables ISO
IBA		 (PMID:12356756)
PMID:21873635		 RGD PMID:12356756 PMID:21873635 RGD:13792537 NCBI chr18:26,872,423...27,104,365
Ensembl chr18:26,872,429...27,104,332 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20538
    molecular function regulator activity 2150
      ATPase regulator activity 46
        adenyl-nucleotide exchange factor activity 10
Path 2
Term Annotations click to browse term
  molecular_function 20538
    binding 17434
      organic cyclic compound binding 6043
        nucleoside phosphate binding 2265
          nucleotide binding 2265
            purine nucleotide binding 2105
              adenyl nucleotide binding 1722
                adenyl-nucleotide exchange factor activity 10
paths to the root