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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA double-strand break processing
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Accession:GO:0000729 term browser browse the term
Definition:The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.



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DNA double-strand break processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase involved_in ISO (PMID:21325134) RGD PMID:21325134 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Dna2 DNA replication helicase/nuclease 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:21325134)
UniProt
Ensembl
RGD
PMID:21325134 GO_REF:0000024 GO_REF:0000107 NCBI chr20:25,661,652...25,690,598 JBrowse link
G Exd2 exonuclease 3'-5' domain containing 2 involved_in ISO (PMID:26807646) RGD PMID:26807646 NCBI chr 6:100,116,867...100,150,452
Ensembl chr 6:100,116,867...100,150,442
JBrowse link
G Setmar SET domain and mariner transposase fusion gene involved_in ISO (PMID:21491884) RGD PMID:21491884 NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197
JBrowse link
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` involved_in ISO
ISS
(PMID:22960744)
GO_REF:0000024
RGD
UniProt
PMID:22960744 GO_REF:0000024 NCBI chr 4:94,311,441...94,379,184
Ensembl chr 4:94,311,489...94,372,563
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N involved_in ISO (PMID:17349954) RGD PMID:17349954 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 involved_in ISO (PMID:17349954) RGD PMID:17349954 NCBI chr11:85,304,528...85,338,430
Ensembl chr11:85,304,526...85,336,369
JBrowse link
DNA double-strand break processing involved in repair via single-strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07031480.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Rad52 RAD52 homolog, DNA repair protein involved_in
acts_upstream_of_or_within
ISO (MGI:5619739|PMID:22912580)
(PMID:19506022)
RGD PMID:19506022 PMID:22912580 MGI:5619739 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000002
(PMID:18716619), (PMID:19202191)
InterPro
RGD
PMID:18716619 PMID:19202191 PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
JBrowse link
G RGD1565844 similar to RIKEN cDNA 1700045I19 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:30,739,541...30,740,614
Ensembl chr  X:30,739,413...30,740,613
JBrowse link
G Rnf138 ring finger protein 138 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:26502057)
UniProt
RGD
PMID:26502057 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr18:12,291,557...12,315,931 JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:19595721) RGD PMID:19595721 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775
JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:19595721) RGD PMID:19595721 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295
JBrowse link
meiotic DNA double-strand break processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slx4 SLX4 structure-specific endonuclease subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295
JBrowse link
G Spo11 SPO11, initiator of meiotic double stranded breaks involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:161,755,299...161,770,930
Ensembl chr 3:161,757,519...161,770,925
JBrowse link
meiotic DNA double-strand break processing involved in reciprocal meiotic recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brip1 BRCA1 interacting helicase 1 acts_upstream_of_or_within ISO MGI:4129733 (MGI:5700253|PMID:26490168) RGD PMID:26490168 MGI:5700253 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Six6os1 Six6 opposite strand transcript 1 involved_in IBA
ISO
PMID:21873635
(MGI:5822939|PMID:27796301)
RGD PMID:27796301 PMID:21873635 MGI:5822939, RGD:13792537 NCBI chr 6:91,579,185...91,615,183
Ensembl chr 6:91,579,325...91,615,148
JBrowse link
regulation of DNA double-strand break processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Helb DNA helicase B involved_in ISO (PMID:26774285)
(MGI:5766842|PMID:26774285)
RGD PMID:26774285 MGI:5766842 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
JBrowse link
G Wdr70 WD repeat domain 70 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:56,951,345...57,191,244
Ensembl chr 2:56,951,355...57,191,187
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      cellular metabolic process 10656
        cellular macromolecule metabolic process 8148
          DNA metabolic process 878
            DNA double-strand break processing 19
              DNA double-strand break processing involved in repair via single-strand annealing 7
              DNA double-strand break processing involved in repair via synthesis-dependent strand annealing 0
              meiotic DNA double-strand break processing + 4
              regulation of DNA double-strand break processing 2
Path 2
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      cellular metabolic process 10656
        cellular nitrogen compound metabolic process 6503
          nucleobase-containing compound metabolic process 5360
            nucleic acid metabolic process 4874
              DNA metabolic process 878
                DNA repair 485
                  double-strand break repair 254
                    DNA double-strand break processing 19
                      DNA double-strand break processing involved in repair via single-strand annealing 7
                      DNA double-strand break processing involved in repair via synthesis-dependent strand annealing 0
                      meiotic DNA double-strand break processing + 4
                      regulation of DNA double-strand break processing 2
paths to the root