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ONTOLOGY REPORT - ANNOTATIONS

Term:double-strand break repair via homologous recombination
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Accession:GO:0000724 term browser browse the term
Definition:The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
Synonyms:exact_synonym: HDR;   HRR;   Rad51-dependent recombinational repair;   Rhp51-dependent recombinational repair;   homologous recombinational repair;   homology-directed repair
 alt_id: GO:0016924


show annotations for term's descendants           Sort by:
double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07031480.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Ankle1 ankyrin repeat and LEM domain containing 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729 		JBrowse link
G Ap5s1 adaptor related protein complex 5 subunit sigma 1 involved_in ISO (PMID:20613862) RGD PMID:20613862 NCBI chr 3:118,429,618...118,432,929
Ensembl chr 3:118,429,637...118,432,926 		JBrowse link
G Ap5z1 adaptor related protein complex 5 subunit zeta 1 involved_in ISO (PMID:20613862) RGD PMID:20613862 NCBI chr12:12,093,834...12,109,043
Ensembl chr12:12,093,834...12,108,511 		JBrowse link
G Atm ATM serine/threonine kinase acts_upstream_of_or_within
involved_in		 ISO MGI:1857132 (PMID:19061978)
(PMID:10802669)		 RGD PMID:10802669 PMID:19061978 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Aunip aurora kinase A and ninein interacting protein involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29042561)		 UniProt
Ensembl
RGD		 PMID:29042561 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:146,722,329...146,734,924
Ensembl chr 5:146,722,337...146,736,501 		JBrowse link
G Blm BLM RecQ like helicase involved_in ISO
IBA		 (PMID:23543748)
GO_REF:0000033		 RGD
GO_Central		 PMID:23543748 GO_REF:0000033 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
GO_REF:0000118
(PMID:17349954), (PMID:28398198)		 Ensembl
GO_Central
TreeGrafter
RGD		 PMID:17349954 PMID:28398198 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
ISS		 GO_REF:0000107
MGI:2653913|MGI:2653914 (PMID:15485900)
GO_REF:0000118
GO_REF:0000033
GO_REF:0000002
(PMID:20729832), (PMID:21719596), (PMID:28398198)
GO_REF:0000024		 Ensembl
RGD
TreeGrafter
GO_Central
InterPro
UniProt		 PMID:15485900 PMID:20729832 PMID:21719596 PMID:28398198 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 involved_in ISO (PMID:25593309) RGD PMID:25593309 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Dmc1 DNA meiotic recombinase 1 involved_in ISO (PMID:17639081) RGD PMID:17639081 NCBI chr 7:111,124,888...111,167,465
Ensembl chr 7:111,124,888...111,167,952 		JBrowse link
G Epc1 enhancer of polycomb homolog 1 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO
IBA		 (PMID:14728600)
GO_REF:0000033		 RGD
GO_Central		 PMID:14728600 GO_REF:0000033 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Ercc4l1 excision repair cross-complementing rodent repair deficiency, complementation group 4-like 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr10:954,927...983,651
Ensembl chr10:954,977...983,174 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease involved_in ISO (PMID:26833090) RGD PMID:26833090 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Exd2 exonuclease 3'-5' domain containing 2 involved_in ISO (PMID:26807646) RGD PMID:26807646 NCBI chr 6:100,116,867...100,150,452
Ensembl chr 6:100,116,867...100,150,442 		JBrowse link
G Fan1 FANCD2 and FANCI associated nuclease 1 involved_in ISO (PMID:20603015), (PMID:20603016) RGD PMID:20603015 PMID:20603016 NCBI chr 1:117,915,323...117,945,044
Ensembl chr 1:117,917,099...117,944,977 		JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590 		JBrowse link
G Fsbp fibrinogen silencer binding protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:25,058,003...25,064,276
Ensembl chr 5:25,032,066...25,104,616 		JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:23166748) RGD PMID:23166748 NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401 		JBrowse link
G H2ax H2A.X variant histone acts_upstream_of_or_within ISO MGI:2156048 (PMID:11934988) RGD PMID:11934988 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Helq helicase, POLQ-like involved_in ISO (PMID:19995904) RGD PMID:19995904 NCBI chr14:8,818,582...8,862,926
Ensembl chr14:8,818,592...8,862,960 		JBrowse link
G Htatsf1 HIV-1 Tat specific factor 1 involved_in ISO (PMID:35597237) RGD PMID:35597237 NCBI chr  X:134,935,426...134,949,607
Ensembl chr  X:134,935,426...134,949,607 		JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in ISO
IBA		 (MGI:3690191|PMID:16278671)
GO_REF:0000033		 RGD
GO_Central		 PMID:16278671 GO_REF:0000033 MGI:3690191 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442 		JBrowse link
G Inip INTS3 and NABP interacting protein involved_in ISO (PMID:19683501) RGD PMID:19683501 NCBI chr 5:74,648,392...74,662,628
Ensembl chr 5:74,648,392...74,662,628 		JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:18026119) RGD PMID:18026119 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911 		JBrowse link
G Ints3 integrator complex subunit 3 involved_in ISO (PMID:19683501) RGD PMID:19683501 NCBI chr 2:175,859,421...175,911,683
Ensembl chr 2:175,859,440...175,911,709 		JBrowse link
G Kash5 KASH domain containing 5 acts_upstream_of_or_within ISO (PMID:24062341) RGD PMID:24062341 NCBI chr 1:95,668,918...95,691,353
Ensembl chr 1:95,668,886...95,691,368 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(MGI:6446379|PMID:30297459)
(PMID:27153538)		 UniProt
GO_Central
Ensembl
RGD		 PMID:27153538 PMID:30297459 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:6446379 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Kdm4d lysine demethylase 4D acts_upstream_of_or_within ISO (PMID:24550317) RGD PMID:24550317 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290 		JBrowse link
G LOC120093168 nuclear ubiquitous casein and cyclin-dependent kinase substrate 1-like involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 6:136,594,866...136,595,965
Ensembl chr 6:136,594,855...136,596,600 		JBrowse link
G Mbtd1 mbt domain containing 1 involved_in ISO (PMID:27153538), (PMID:32209463) RGD PMID:27153538 PMID:32209463 NCBI chr10:78,839,140...78,895,413
Ensembl chr10:78,839,036...78,893,720 		JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor involved_in ISO
IBA
IEA
ISS		 (PMID:23401855)
GO_REF:0000033
GO_REF:0000118
(MGI:5437561|PMID:22771120)
GO_REF:0000024		 RGD
GO_Central
TreeGrafter
UniProt		 PMID:22771120 PMID:23401855 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:5437561 NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008 		JBrowse link
G Mcm9 minichromosome maintenance 9 homologous recombination repair factor involved_in ISO
IBA
IEA
ISS		 (PMID:22771115), (PMID:23401855)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
(MGI:5437561|PMID:22771120), (MGI:5525985|PMID:23401855)		 RGD
GO_Central
Ensembl
UniProt		 PMID:22771115 PMID:22771120 PMID:23401855 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5437561 MGI:5525985 NCBI chr20:32,818,219...32,929,577
Ensembl chr20:32,844,951...32,929,600 		JBrowse link
G Meiob meiosis specific with OB-fold involved_in ISS
ISO		 GO_REF:0000024
(MGI:5527015|PMID:24068956), (MGI:5538413|PMID:24240703)		 UniProt
RGD		 PMID:24068956 PMID:24240703 GO_REF:0000024 MGI:5527015 MGI:5538413 NCBI chr10:13,833,170...13,865,684
Ensembl chr10:13,833,750...13,865,046 		JBrowse link
G Mms22l MMS22-like, DNA repair protein involved_in ISO
IBA		 (PMID:21055983), (PMID:21055984), (PMID:21055985), (PMID:27797818)
GO_REF:0000033		 RGD
GO_Central		 PMID:21055983 PMID:21055984 PMID:21055985 PMID:27797818 GO_REF:0000033 NCBI chr 5:38,197,707...38,313,745
Ensembl chr 5:38,197,779...38,313,745 		JBrowse link
G Morf4l1 mortality factor 4 like 1 involved_in ISO
ISS		 (PMID:20332121)
GO_REF:0000024		 RGD
UniProt		 PMID:20332121 GO_REF:0000024 NCBI chr 8:90,642,988...90,664,518
Ensembl chr 8:90,642,988...90,664,519 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in ISS
ISO
IEA
IBA		 GO_REF:0000024
(MGI:3839734|PMID:18854157)
(PMID:15741314), (PMID:24316220), (PMID:27814491), (PMID:27889449), (PMID:28867292), (PMID:29670289), (PMID:30612738), (PMID:30787182), (PMID:31353207), (PMID:36563124), (PMID:38128537)
GO_REF:0000118
GO_REF:0000107
GO_REF:0000033		 UniProt
RGD
TreeGrafter
Ensembl
GO_Central		 PMID:15741314 PMID:18854157 PMID:24316220 PMID:27814491 PMID:27889449 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:3839734 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Nabp1 nucleic acid binding protein 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:19605351), (PMID:19683501)		 UniProt
GO_Central
RGD		 PMID:19605351 PMID:19683501 GO_REF:0000024 GO_REF:0000033 NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107 		JBrowse link
G Nabp2 nucleic acid binding protein 2 involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000118
GO_REF:0000033
GO_REF:0000107
(PMID:19605351), (PMID:19683501)		 UniProt
TreeGrafter
GO_Central
Ensembl
RGD		 PMID:19605351 PMID:19683501 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:830,949...836,551
Ensembl chr 7:830,949...838,027 		JBrowse link
G Nbn nibrin involved_in IEA
ISO
IBA		 GO_REF:0000107
(PMID:22464731), (PMID:23115235), (PMID:27814491), (PMID:27889449), (PMID:28867292), (PMID:30787182), (PMID:30952868)
GO_REF:0000033
GO_REF:0000118		 Ensembl
RGD
GO_Central
TreeGrafter		 PMID:22464731 PMID:23115235 PMID:27814491 PMID:27889449 PMID:28867292 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Nsmce1 NSE1 homolog, SMC5-SMC6 complex component involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:180,030,355...180,058,541
Ensembl chr 1:180,030,160...180,058,417 		JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO
IBA
IEA
ISS		 (PMID:16810316)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
GO_REF:0000024
GO_REF:0000002		 RGD
GO_Central
TreeGrafter
Ensembl
UniProt
InterPro		 PMID:16810316 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899 		JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 involved_in ISO
IEA
IBA		 (PMID:26323318)
GO_REF:0000118
GO_REF:0000033		 RGD
TreeGrafter
GO_Central		 PMID:26323318 GO_REF:0000033 GO_REF:0000118 NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229 		JBrowse link
G Palb2 partner and localizer of BRCA2 involved_in ISO
IBA		 (PMID:19369211), (PMID:19423707), (PMID:26323318), (PMID:28398198)
GO_REF:0000033		 RGD
GO_Central		 PMID:19369211 PMID:19423707 PMID:26323318 PMID:28398198 GO_REF:0000033 NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990 		JBrowse link
G Pogz pogo transposable element derived with ZNF domain acts_upstream_of_or_within_positive_effect ISO (PMID:26721387) RGD PMID:26721387 NCBI chr 2:182,394,269...182,440,711
Ensembl chr 2:182,380,768...182,440,707 		JBrowse link
G Poll DNA polymerase lambda involved_in ISO
ISS		 (PMID:20693240)
GO_REF:0000024		 RGD
UniProt		 PMID:20693240 GO_REF:0000024 NCBI chr 1:244,400,202...244,408,762
Ensembl chr 1:244,400,204...244,408,662 		JBrowse link
G Poln DNA polymerase nu involved_in ISO (PMID:19995904) RGD PMID:19995904 NCBI chr14:76,579,983...76,752,460
Ensembl chr14:76,580,546...76,752,463 		JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:181,392,899...181,399,703
Ensembl chr 1:181,392,923...181,399,659 		JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 involved_in ISO (PMID:22909820) RGD PMID:22909820 NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076 		JBrowse link
G Rad21l1 RAD21 cohesin complex component like 1 acts_upstream_of_or_within ISO MGI:1929645 (PMID:22711701) RGD PMID:22711701 NCBI chr 3:140,160,128...140,188,324
Ensembl chr 3:140,160,118...140,188,298 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:27889449), (PMID:28867292)		 Ensembl
RGD		 PMID:27889449 PMID:28867292 GO_REF:0000107 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rad51 RAD51 recombinase acts_upstream_of_or_within
involved_in		 IEP
ISO		 (PMID:15359272), (PMID:15485900)
(PMID:15834424)
(PMID:17996710), (PMID:17996711), (PMID:18417535), (PMID:22778135), (PMID:23509288), (PMID:26681308), (PMID:26811421), (PMID:27239033), (PMID:32640219)
(PMID:16428451)		 RGD PMID:15359272 PMID:15485900 PMID:15834424 PMID:16428451 PMID:17996710 More... RGD:9831188 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 involved_in ISO
IBA		 (PMID:26323318)
GO_REF:0000033		 RGD
GO_Central		 PMID:26323318 GO_REF:0000033 NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524 		JBrowse link
G Rad51b RAD51 paralog B involved_in ISO
IBA		 (PMID:23149936)
GO_REF:0000033		 RGD
GO_Central		 PMID:23149936 GO_REF:0000033 NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979 		JBrowse link
G Rad51c RAD51 paralog C involved_in ISO (PMID:23149936) RGD PMID:23149936 NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248 		JBrowse link
G Rad51d RAD51 paralog D involved_in ISO
IBA		 (PMID:23149936)
GO_REF:0000033		 RGD
GO_Central		 PMID:23149936 GO_REF:0000033 NCBI chr10:67,805,720...67,824,452
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12379650)		 GO_Central
RGD		 PMID:12379650 GO_REF:0000033 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Rad54b RAD54 homolog B acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:16428451)
MGI:3617695|MGI:894697 (PMID:16428451), (PMID:19061978)
GO_REF:0000033		 RGD
GO_Central		 PMID:16428451 PMID:19061978 GO_REF:0000033 NCBI chr 5:25,032,112...25,104,630
Ensembl chr 5:25,032,066...25,104,616 		JBrowse link
G Rad54l RAD54 like acts_upstream_of_or_within ISO MGI:2183934|MGI:3605986 (PMID:16428451), (PMID:19061978) RGD PMID:16428451 PMID:19061978 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease involved_in ISS
ISO		 GO_REF:0000024
(PMID:26721387), (PMID:27814491), (PMID:27889449), (PMID:30787182)		 UniProt
RGD		 PMID:26721387 PMID:27814491 PMID:27889449 PMID:30787182 GO_REF:0000024 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846 		JBrowse link
G Rec8 REC8 meiotic recombination protein acts_upstream_of_or_within ISO MGI:3652039 (PMID:22711701) RGD PMID:22711701 NCBI chr15:29,109,862...29,117,327
Ensembl chr15:29,109,863...29,117,326 		JBrowse link
G Recql RecQ like helicase involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945 		JBrowse link
G Recql4 RecQ like helicase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619 		JBrowse link
G Recql5 RecQ like helicase 5 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652 		JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:43,131,841...43,290,102
Ensembl chr20:43,132,363...43,290,099 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:67,740,711...67,803,669
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:26474068), (PMID:28575657), (PMID:28575658), (PMID:28691929) RGD PMID:26474068 PMID:28575657 PMID:28575658 PMID:28691929 NCBI chr19:39,235,883...39,268,479
Ensembl chr19:39,236,787...39,268,479 		JBrowse link
G Rmi1 RecQ mediated genome instability 1 involved_in ISO
IBA		 (PMID:23543748)
GO_REF:0000033		 RGD
GO_Central		 PMID:23543748 GO_REF:0000033 NCBI chr17:6,256,533...6,264,523
Ensembl chr17:6,256,450...6,264,695 		JBrowse link
G Rmi2 RecQ mediated genome instability 2 involved_in ISO (PMID:23543748) RGD PMID:23543748 NCBI chr10:4,829,333...4,837,264
Ensembl chr10:4,830,553...4,837,235 		JBrowse link
G Rnf138 ring finger protein 138 involved_in ISO
IEA
IBA
ISS		 (PMID:26502055), (PMID:26502057)
GO_REF:0000118
GO_REF:0000033
GO_REF:0000024		 RGD
TreeGrafter
GO_Central
UniProt		 PMID:26502055 PMID:26502057 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930 		JBrowse link
G Rnf138l1 ring finger protein 138 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:30,739,541...30,740,614
Ensembl chr  X:30,739,413...30,740,613 		JBrowse link
G Rnf169 ring finger protein 169 involved_in ISO (PMID:22492721) RGD PMID:22492721 NCBI chr 1:154,250,462...154,311,867
Ensembl chr 1:154,254,473...154,311,653 		JBrowse link
G Rpa1 replication protein A1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17765923)
MGI:3582609 (PMID:15470499)
GO_REF:0000033		 RGD
GO_Central		 PMID:15470499 PMID:17765923 GO_REF:0000033 NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949 		JBrowse link
G Rpa2 replication protein A2 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(PMID:17765923)		 UniProt
GO_Central
TreeGrafter
RGD		 PMID:17765923 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Rpa3 replication protein A3 involved_in ISO
IBA		 (PMID:17765923)
GO_REF:0000033		 RGD
GO_Central		 PMID:17765923 GO_REF:0000033 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709 		JBrowse link
G Rpa3l1 replication protein A3 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:45,908,653...45,909,063
Ensembl chr12:45,908,683...45,909,048 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:28834754), (PMID:29670289) RGD PMID:28834754 PMID:29670289 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Sem1 SEM1 26S proteasome subunit involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:15359272)		 GO_Central
RGD		 PMID:15359272 GO_REF:0000033 NCBI chr 4:34,671,848...34,692,005
Ensembl chr 4:34,671,848...34,692,005 		JBrowse link
G Sfpq splicing factor proline and glutamine rich acts_upstream_of_or_within ISO (PMID:20813759) RGD PMID:20813759 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472 		JBrowse link
G Sfr1 SWI5-dependent homologous recombination repair protein 1 involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(MGI:4868525|PMID:20976249)
GO_REF:0000107
(PMID:21252223)		 UniProt
GO_Central
RGD
Ensembl		 PMID:20976249 PMID:21252223 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:4868525 NCBI chr 1:246,619,235...246,623,250
Ensembl chr 1:246,597,044...246,623,250 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO
IEA
IBA		 (PMID:19595721)
GO_REF:0000118
GO_REF:0000033		 RGD
TreeGrafter
GO_Central		 PMID:19595721 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:19595721), (PMID:19596235) RGD PMID:19595721 PMID:19596235 NCBI chr10:11,526,623...11,549,313
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
G Smc5 structural maintenance of chromosomes 5 involved_in ISO
IBA		 (PMID:16810316)
GO_REF:0000033		 RGD
GO_Central		 PMID:16810316 GO_REF:0000033 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096 		JBrowse link
G Smc6 structural maintenance of chromosomes 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746 		JBrowse link
G Spidr scaffold protein involved in DNA repair involved_in ISO
IBA		 (PMID:23509288), (PMID:27967308), (PMID:34697795)
GO_REF:0000033		 RGD
GO_Central		 PMID:23509288 PMID:27967308 PMID:34697795 GO_REF:0000033 NCBI chr11:84,766,593...85,007,597
Ensembl chr11:84,766,593...85,007,600 		JBrowse link
G Swi5 SWI5 homologous recombination repair protein involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(MGI:4868525|PMID:20976249)
(PMID:21252223)		 UniProt
GO_Central
RGD		 PMID:20976249 PMID:21252223 GO_REF:0000024 GO_REF:0000033 MGI:4868525 NCBI chr 3:15,574,687...15,583,760
Ensembl chr 3:15,564,715...15,583,805 		JBrowse link
G Swsap1 SWIM-type zinc finger 7 associated protein 1 involved_in ISO
IBA		 (PMID:21965664)
GO_REF:0000033		 RGD
GO_Central		 PMID:21965664 GO_REF:0000033 NCBI chr 8:20,486,680...20,489,213
Ensembl chr 8:20,486,678...20,489,211 		JBrowse link
G Tonsl tonsoku-like, DNA repair protein involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:21055983), (PMID:21055984), (PMID:21055985), (PMID:27338793), (PMID:27797818), (PMID:30773278)		 UniProt
GO_Central
RGD		 PMID:21055983 PMID:21055984 PMID:21055985 PMID:27338793 PMID:27797818 More... GO_REF:0000024 GO_REF:0000033 NCBI chr 7:108,345,704...108,360,792
Ensembl chr 7:108,346,047...108,360,750 		JBrowse link
G Top3a DNA topoisomerase III alpha involved_in ISO (PMID:23543748) RGD PMID:23543748 NCBI chr10:45,419,219...45,457,356
Ensembl chr10:45,419,217...45,457,559 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in ISO (PMID:26811421), (PMID:35597237) RGD PMID:26811421 PMID:35597237 NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674 		JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N involved_in ISO (PMID:17349954) RGD PMID:17349954 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355 		JBrowse link
G Wdr48 WD repeat domain 48 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3877670 (PMID:24001775)		 GO_Central
RGD		 PMID:24001775 GO_REF:0000033 NCBI chr 8:119,622,053...119,655,264
Ensembl chr 8:119,622,048...119,655,264 		JBrowse link
G Wrn WRN RecQ like helicase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450 		JBrowse link
G Xrcc2 X-ray repair cross complementing 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:23149936)
MGI:3654106 (PMID:16777961)
GO_REF:0000033		 RGD
GO_Central		 PMID:16777961 PMID:23149936 GO_REF:0000033 NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO (PMID:23149936) RGD PMID:23149936 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
G Yy1 YY1 transcription factor involved_in ISO (PMID:18026119) RGD PMID:18026119 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
G Zfyve26 zinc finger FYVE-type containing 26 involved_in ISO
IEA		 (PMID:20613862)
GO_REF:0000107
GO_REF:0000002		 RGD
Ensembl
InterPro		 PMID:20613862 GO_REF:0000002 GO_REF:0000107 NCBI chr 6:98,031,874...98,095,538
Ensembl chr 6:98,032,520...98,095,480 		JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 involved_in ISO (PMID:25593309) RGD PMID:25593309 NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463 		JBrowse link
G Zswim7 zinc finger, SWIM-type containing 7 involved_in ISO
IBA		 (PMID:21965664)
GO_REF:0000033		 RGD
GO_Central		 PMID:21965664 GO_REF:0000033 NCBI chr10:46,953,311...46,969,800
Ensembl chr10:46,957,525...46,969,671 		JBrowse link
DNA recombinase assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmc1 DNA meiotic recombinase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:111,124,888...111,167,465
Ensembl chr 7:111,124,888...111,167,952 		JBrowse link
G Rad51 RAD51 recombinase involved_in ISO
IBA		 (PMID:26681308)
GO_REF:0000033		 RGD
GO_Central		 PMID:26681308 GO_REF:0000033 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
double-strand break repair via break-induced replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC129365.1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 2:141,551,434...141,554,016 JBrowse link
G Cdc45 cell division cycle 45 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Cdc7 cell division cycle 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778 		JBrowse link
G Gins2 GINS complex subunit 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339 		JBrowse link
G Gins4 GINS complex subunit 4 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063 		JBrowse link
G Mcmdc2 minichromosome maintenance domain containing 2 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:9,291,967...9,337,526
Ensembl chr 5:9,298,101...9,338,300 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit involved_in IEA
IBA		 GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:202,790,295...202,796,008
Ensembl chr 1:202,790,466...202,795,843 		JBrowse link
double-strand break repair via synthesis-dependent strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr  X:67,245,414...67,261,222
Ensembl chr  X:67,245,414...67,280,756 		JBrowse link
G Ercc6l2 ERCC excision repair 6 like 2 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr17:1,076,486...1,311,281
Ensembl chr17:1,216,428...1,310,275 		JBrowse link
G Fancm FA complementation group M involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:83,126,903...83,180,455
Ensembl chr 6:83,127,093...83,180,028 		JBrowse link
G Helq helicase, POLQ-like involved_in ISO (PMID:34937945) RGD PMID:34937945 NCBI chr14:8,818,582...8,862,926
Ensembl chr14:8,818,592...8,862,960 		JBrowse link
G Rad54b RAD54 homolog B involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 5:25,032,112...25,104,630
Ensembl chr 5:25,032,066...25,104,616 		JBrowse link
G Rad54l RAD54 like involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
late meiotic recombination nodule assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mcmdc2 minichromosome maintenance domain containing 2 acts_upstream_of_or_within ISO MGI:2178050|MGI:5511194 (PMID:27760146) RGD PMID:27760146 NCBI chr 5:9,291,967...9,337,526
Ensembl chr 5:9,298,101...9,338,300 		JBrowse link
meiotic DNA recombinase assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rad51c RAD51 paralog C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248 		JBrowse link
meiotic DNA recombinase assembly involved in reciprocal meiotic recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Swi5 SWI5 homologous recombination repair protein involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 3:15,574,687...15,583,760
Ensembl chr 3:15,564,715...15,583,805 		JBrowse link
meiotic recombination nodule assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mcmdc2 minichromosome maintenance domain containing 2 acts_upstream_of_or_within ISO MGI:2178050|MGI:5511194 (PMID:27760146) RGD PMID:27760146 NCBI chr 5:9,291,967...9,337,526
Ensembl chr 5:9,298,101...9,338,300 		JBrowse link
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:9461559) RGD PMID:9461559 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G C1qbp complement C1q binding protein involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:31353207)		 Ensembl
UniProt
RGD		 PMID:31353207 GO_REF:0000024 GO_REF:0000107 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO
IBA		 (PMID:30356214), (PMID:31544964)
(MGI:6241455|PMID:30356214), (MGI:6370284|PMID:31544964)
GO_REF:0000033		 RGD
GO_Central		 PMID:30356214 PMID:31544964 GO_REF:0000033 MGI:6241455 MGI:6370284 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28512243)		 UniProt
RGD		 PMID:28512243 GO_REF:0000024 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Fancb FA complementation group B involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2156841 (PMID:25520194)		 GO_Central
RGD		 PMID:25520194 GO_REF:0000033 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192 		JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in ISO (PMID:19736316)
(MGI:5566975|PMID:24108124)		 RGD PMID:19736316 PMID:24108124 MGI:5566975 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590 		JBrowse link
G Helb DNA helicase B involved_in ISO (PMID:26774285)
(MGI:5766842|PMID:26774285)		 RGD PMID:26774285 MGI:5766842 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISO
IEA		 (PMID:32832608)
GO_REF:0000107		 RGD
Ensembl		 PMID:32832608 GO_REF:0000107 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Klhl15 kelch-like family member 15 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27561354), (PMID:35219381)		 UniProt
RGD		 PMID:27561354 PMID:35219381 GO_REF:0000024 NCBI chr  X:58,994,726...59,050,207
Ensembl chr  X:58,995,461...59,046,069 		JBrowse link
G Kmt5a lysine methyltransferase 5A involved_in ISO (PMID:27338793) RGD PMID:27338793 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693 		JBrowse link
G Parpbp PARP1 binding protein involved_in ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:22153967)
GO_REF:0000002
GO_REF:0000033
GO_REF:0000118		 UniProt
RGD
InterPro
GO_Central
TreeGrafter		 PMID:22153967 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:22,511,427...22,580,834
Ensembl chr 7:22,511,427...22,573,695 		JBrowse link
G Plk1 polo-like kinase 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:28512243)		 Ensembl
UniProt
RGD		 PMID:28512243 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Polq DNA polymerase theta involved_in ISO (PMID:25642963), (PMID:28695890), (PMID:36455556)
(MGI:5621198|PMID:25642960), (MGI:5920742|PMID:28687761), (MGI:6869820|PMID:29058711)		 RGD PMID:25642960 PMID:25642963 PMID:28687761 PMID:28695890 PMID:29058711 More... MGI:5621198 MGI:5920742 MGI:6869820 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878 		JBrowse link
G Radx RPA1 related single stranded DNA binding protein, X-linked involved_in ISO
ISS
IEA		 (PMID:28735897)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:28735897 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:103,089,284...103,176,840
Ensembl chr  X:103,089,284...103,176,838 		JBrowse link
G Recql5 RecQ like helicase 5 acts_upstream_of_or_within ISO MGI:2448558 (PMID:25520194) RGD PMID:25520194 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:23333306)
(MGI:5468037|PMID:23306437), (MGI:5476381|PMID:23333305)		 RGD PMID:23306437 PMID:23333305 PMID:23333306 MGI:5468037 MGI:5476381 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617 		JBrowse link
G Rmi2 RecQ mediated genome instability 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:4,829,333...4,837,264
Ensembl chr10:4,830,553...4,837,235 		JBrowse link
G Senp3 SUMO specific peptidase 3 involved_in ISO (PMID:32832608) RGD PMID:32832608 NCBI chr10:54,390,698...54,399,590
Ensembl chr10:54,390,694...54,399,593 		JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA		 (PMID:29656893)
GO_REF:0000033		 RGD
GO_Central		 PMID:29656893 GO_REF:0000033 NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965 		JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:35,297,255...35,302,071
Ensembl chr 2:35,295,859...35,302,346 		JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:25294876) RGD PMID:25294876 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23333306), (PMID:23345425)
(MGI:5476381|PMID:23333305), (MGI:5887194|PMID:20362325)		 RGD PMID:20362325 PMID:23333305 PMID:23333306 PMID:23345425 MGI:5476381 MGI:5887194 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
G Ubqln4 ubiquilin 4 involved_in ISO (PMID:30612738) RGD PMID:30612738 NCBI chr 2:174,012,726...174,028,062
Ensembl chr 2:174,012,777...174,028,059 		JBrowse link
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta involved_in ISO
IEA		 (PMID:27153538)
GO_REF:0000107		 RGD
Ensembl		 PMID:27153538 GO_REF:0000107 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actl6a actin-like 6A involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 2:115,492,374...115,508,401
Ensembl chr 2:115,492,285...115,508,401 		JBrowse link
G Actr2 actin related protein 2 involved_in ISO
IEA
ISS		 (PMID:29925947)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29925947 GO_REF:0000024 GO_REF:0000107 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524 		JBrowse link
G Arid2 AT-rich interaction domain 2 involved_in ISO (PMID:28381560) RGD PMID:28381560 NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512 		JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO MGI:2448558 (PMID:25520194) RGD PMID:25520194 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Brd8 bromodomain containing 8 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr18:26,204,892...26,229,999
Ensembl chr18:26,181,732...26,229,884 		JBrowse link
G Crebbp CREB binding protein involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:38128537)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:38128537 GO_REF:0000024 GO_REF:0000107 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Dmap1 DNA methyltransferase 1-associated protein 1 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 5:131,143,726...131,151,760
Ensembl chr 5:131,143,729...131,151,742 		JBrowse link
G Ep400 E1A binding protein p400 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861 		JBrowse link
G Epc1 enhancer of polycomb homolog 1 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425 		JBrowse link
G Epc2 enhancer of polycomb homolog 2 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 3:33,867,219...33,967,908
Ensembl chr 3:33,867,219...33,967,150 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Fancb FA complementation group B involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1328362 (PMID:25520194)		 GO_Central
RGD		 PMID:25520194 GO_REF:0000033 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192 		JBrowse link
G Fus Fus RNA binding protein involved_in ISO (PMID:10567410) RGD PMID:10567410 NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414 		JBrowse link
G Hdgfl2 HDGF like 2 involved_in ISO
IEA
ISS		 (PMID:26721387)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26721387 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:909,581...929,195
Ensembl chr 9:909,614...929,186 		JBrowse link
G Helq helicase, POLQ-like involved_in ISO (MGI:5547892|PMID:24005329) RGD PMID:24005329 MGI:5547892 NCBI chr14:8,818,582...8,862,926
Ensembl chr14:8,818,592...8,862,960 		JBrowse link
G Ing3 inhibitor of growth family, member 3 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 4:50,477,954...50,505,168
Ensembl chr 4:50,477,962...50,503,715 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27153538), (PMID:32832608)		 UniProt
Ensembl
RGD		 PMID:27153538 PMID:32832608 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member involved_in ISO
ISS		 (PMID:31609975)
(MGI:6716962|PMID:25936915)
GO_REF:0000024		 RGD
UniProt		 PMID:25936915 PMID:31609975 GO_REF:0000024 MGI:6716962 NCBI chr 8:73,842,344...73,844,248
Ensembl chr 8:73,842,344...73,844,248 		JBrowse link
G Mbtd1 mbt domain containing 1 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr10:78,839,140...78,895,413
Ensembl chr10:78,839,036...78,893,720 		JBrowse link
G Meaf6 MYST/Esa1-associated factor 6 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 5:137,344,681...137,369,703
Ensembl chr 5:137,344,380...137,370,014 		JBrowse link
G Morf4l1 mortality factor 4 like 1 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 8:90,642,988...90,664,518
Ensembl chr 8:90,642,988...90,664,519 		JBrowse link
G Morf4l2 mortality factor 4 like 2 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr  X:100,082,562...100,093,658
Ensembl chr  X:100,082,404...100,093,728 		JBrowse link
G Mrgbp MRG domain binding protein involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 3:167,697,129...167,700,592
Ensembl chr 3:167,697,185...167,700,592 		JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO (PMID:27568553) RGD PMID:27568553 NCBI chr10:34,501,359...34,525,474
Ensembl chr10:34,501,384...34,525,469 		JBrowse link
G Ooep oocyte expressed protein involved_in ISO (MGI:6272426|PMID:29955025) RGD PMID:29955025 MGI:6272426 NCBI chr 8:79,223,388...79,224,554
Ensembl chr 8:79,223,375...79,224,541 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO
ISS		 (PMID:26344098), (PMID:30356214)
GO_REF:0000024		 RGD
UniProt		 PMID:26344098 PMID:30356214 GO_REF:0000024 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 involved_in ISO (PMID:30952868) RGD PMID:30952868 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285 		JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 involved_in ISO (PMID:32832608) RGD PMID:32832608 NCBI chr 7:8,546,312...8,559,838
Ensembl chr 7:8,546,312...8,559,808 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15741314), (PMID:29651020)		 UniProt
RGD		 PMID:15741314 PMID:29651020 GO_REF:0000024 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 involved_in ISO (PMID:17996710), (PMID:17996711) RGD PMID:17996710 PMID:17996711 NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524 		JBrowse link
G Rnf126 ring finger protein 126 involved_in IEA
ISO		 GO_REF:0000107
(PMID:36563124)		 Ensembl
RGD		 PMID:36563124 GO_REF:0000107 NCBI chr 7:9,939,359...9,946,963
Ensembl chr 7:9,938,229...9,946,738 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23115235)		 UniProt
RGD		 PMID:23115235 GO_REF:0000024 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G Skp2 S-phase kinase associated protein 2 involved_in ISO (PMID:22464731)
(MGI:5438910|PMID:22464731)		 RGD PMID:22464731 MGI:5438910 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Timeless timeless circadian regulator involved_in ISO
IEA
ISS		 (PMID:26344098), (PMID:30356214)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26344098 PMID:30356214 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738 		JBrowse link
G Trrap transformation/transcription domain-associated protein involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr12:9,738,006...9,827,708
Ensembl chr12:9,738,006...9,827,674 		JBrowse link
G Vps72 vacuolar protein sorting 72 homolog involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 2:182,678,594...182,690,185
Ensembl chr 2:182,678,609...182,690,182 		JBrowse link
G Was WASP actin nucleation promoting factor involved_in ISO (PMID:29925947) RGD PMID:29925947 NCBI chr  X:14,405,105...14,413,850
Ensembl chr  X:14,405,124...14,413,849 		JBrowse link
G Wdr48 WD repeat domain 48 involved_in ISO (PMID:27239033), (PMID:27463890) RGD PMID:27239033 PMID:27463890 NCBI chr 8:119,622,053...119,655,264
Ensembl chr 8:119,622,048...119,655,264 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISO
ISS		 (PMID:25512560)
GO_REF:0000024		 RGD
UniProt		 PMID:25512560 GO_REF:0000024 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
G Yeats4 YEATS domain containing 4 involved_in ISO (PMID:27153538) RGD PMID:27153538 NCBI chr 7:52,858,313...52,865,454
Ensembl chr 7:52,858,305...52,865,635 		JBrowse link
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek1 checkpoint kinase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15665856)		 UniProt
RGD		 PMID:15665856 GO_REF:0000024 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Fignl1 fidgetin-like 1 involved_in ISO
ISS		 (PMID:23754376)
GO_REF:0000024		 RGD
UniProt		 PMID:23754376 GO_REF:0000024 NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455 		JBrowse link
G Kdm1a lysine demethylase 1A acts_upstream_of_or_within ISO (PMID:24217620) RGD PMID:24217620 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:20154705)		 Ensembl
UniProt
RGD		 PMID:20154705 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,392,899...181,399,703
Ensembl chr 1:181,392,923...181,399,659 		JBrowse link
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 involved_in ISO (PMID:20154705) RGD PMID:20154705 NCBI chr 4:133,454,555...133,495,486
Ensembl chr 4:133,454,555...133,495,486 		JBrowse link
G Rad51 RAD51 recombinase involved_in ISO (PMID:23754376) RGD PMID:23754376 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 involved_in ISO (PMID:23754376) RGD PMID:23754376 NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524 		JBrowse link
G Rpa2 replication protein A2 involved_in ISO
ISS		 (PMID:20154705)
GO_REF:0000024		 RGD
UniProt		 PMID:20154705 GO_REF:0000024 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000104
(PMID:18957201)		 UniProt
GO_Central
RGD		 PMID:18957201 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase involved_in ISO (PMID:24843002) RGD PMID:24843002 NCBI chr 8:110,511,808...110,597,475
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:19135889), (PMID:22753495) RGD PMID:19135889 PMID:22753495 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Spidr scaffold protein involved in DNA repair involved_in ISO (PMID:23754376) RGD PMID:23754376 NCBI chr11:84,766,593...85,007,597
Ensembl chr11:84,766,593...85,007,600 		JBrowse link
G Terf2ip TERF2 interacting protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:4440768|PMID:20339076)		 UniProt
RGD		 PMID:20339076 GO_REF:0000024 MGI:4440768 NCBI chr19:39,976,965...39,984,055
Ensembl chr19:39,976,906...39,984,064 		JBrowse link
G Tex15 testis expressed 15, meiosis and synapsis associated involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3526165 (PMID:18283110)		 GO_Central
RGD		 PMID:18283110 GO_REF:0000033 NCBI chr16:58,598,991...58,659,005
Ensembl chr16:58,598,989...58,658,467 		JBrowse link
G Usp51 ubiquitin specific peptidase 51 involved_in ISO (PMID:27083998) RGD PMID:27083998 NCBI chr  X:18,374,940...18,381,472
Ensembl chr  X:18,376,930...18,379,888 		JBrowse link
G Zfp365 zinc finger protein 365 involved_in ISS
IBA
IEA		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107		 UniProt
GO_Central
TreeGrafter
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr20:20,666,240...20,689,734
Ensembl chr20:20,666,240...20,691,238 		JBrowse link
replication-born double-strand break repair via sister chromatid exchange term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO (PMID:25597246) RGD PMID:25597246 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Fancb FA complementation group B involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:25520194)		 GO_Central
RGD		 PMID:25520194 GO_REF:0000033 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899 		JBrowse link
G Rad21 RAD21 cohesin complex component involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817 		JBrowse link
G Rad21l1 RAD21 cohesin complex component like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:140,160,128...140,188,324
Ensembl chr 3:140,160,118...140,188,298 		JBrowse link
G Rad51 RAD51 recombinase acts_upstream_of_or_within ISO MGI:5444025|MGI:5444027 (PMID:22778135) RGD PMID:22778135 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rec8 REC8 meiotic recombination protein involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr15:29,109,862...29,117,327
Ensembl chr15:29,109,863...29,117,326 		JBrowse link
G Recql5 RecQ like helicase 5 acts_upstream_of_or_within ISO (PMID:25520194) RGD PMID:25520194 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO (PMID:28002403) RGD PMID:28002403 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular response to stimulus 9075
        cellular response to stress 2061
          DNA damage response 891
            DNA repair 561
              double-strand break repair 308
                double-strand break repair via homologous recombination 185
                  DNA synthesis involved in double-strand break repair via homologous recombination 0
                  double-strand break repair via break-induced replication + 13
                  double-strand break repair via synthesis-dependent strand annealing + 14
                  double-strand break repair via transcription-associated homologous recombination 0
                  negative regulation of double-strand break repair via homologous recombination + 25
                  positive regulation of double-strand break repair via homologous recombination 43
                  regulation of double-strand break repair via homologous recombination + 81
                  replication-born double-strand break repair via sister chromatid exchange 9
Path 2
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      organic substance metabolic process 11328
        organic cyclic compound metabolic process 6260
          nucleobase-containing compound metabolic process 5743
            nucleic acid metabolic process 5144
              DNA metabolic process 991
                DNA repair 561
                  recombinational repair 188
                    double-strand break repair via homologous recombination 185
                      DNA synthesis involved in double-strand break repair via homologous recombination 0
                      double-strand break repair via break-induced replication + 13
                      double-strand break repair via synthesis-dependent strand annealing + 14
                      double-strand break repair via transcription-associated homologous recombination 0
                      negative regulation of double-strand break repair via homologous recombination + 25
                      positive regulation of double-strand break repair via homologous recombination 43
                      regulation of double-strand break repair via homologous recombination + 81
                      replication-born double-strand break repair via sister chromatid exchange 9
paths to the root