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ONTOLOGY REPORT - ANNOTATIONS

Term:double-strand break repair via homologous recombination
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Accession:GO:0000724 term browser browse the term
Definition:The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
Synonyms:exact_synonym: HDR;   HRR;   Rad51-dependent recombinational repair;   Rhp51-dependent recombinational repair;   homologous recombinational repair;   homology-directed repair
 alt_id: GO:0016924
 xref: Reactome:R-HSA-5693538 "Homology Directed Repair"


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double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE1 ankyrin repeat and LEM domain containing 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:45,461,135...45,465,922
Ensembl chr20:45,461,676...45,465,417 		JBrowse link
G AP5S1 adaptor related protein complex 5 subunit sigma 1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr24:17,537,539...17,543,834
Ensembl chr24:17,537,544...17,543,901 		JBrowse link
G AP5Z1 adaptor related protein complex 5 subunit zeta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,847,699...12,858,769
Ensembl chr 6:12,847,713...12,858,681 		JBrowse link
G ASTE1 asteroid homolog 1 involved_in ISO (PMID:34354233) UniProt PMID:34354233 NCBI chr23:28,233,165...28,244,036
Ensembl chr23:28,231,032...28,243,768 		JBrowse link
G ASTE1 asteroid homolog 1 involved_in IEA Ensembl GO_REF:0000107
G ATM ATM serine/threonine kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19061978) MGI
Ensembl		 PMID:19061978 GO_REF:0000107 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207 		JBrowse link
G AUNIP aurora kinase A and ninein interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,097,435...74,116,824
Ensembl chr 2:74,097,508...74,118,085 		JBrowse link
G BLM BLM RecQ like helicase involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:53,408,120...53,506,728
Ensembl chr 3:53,408,217...53,473,146 		JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:19,958,941...20,025,494
Ensembl chr 9:19,958,391...20,025,494 		JBrowse link
G BRCA2 BRCA2 DNA repair associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15485900) InterPro
MGI		 PMID:15485900 GO_REF:0000002 NCBI chr25:7,734,450...7,797,851
Ensembl chr25:7,734,453...7,797,815 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,411,009...38,440,367
Ensembl chr27:38,411,075...38,439,958 		JBrowse link
G DMC1 DNA meiotic recombinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:26,228,662...26,265,377
Ensembl chr10:26,230,428...26,264,820 		JBrowse link
G EPC1 enhancer of polycomb homolog 1 involved_in ISO (PMID:27153538) UniProt PMID:27153538 NCBI chr 2:14,566,177...14,659,774
Ensembl chr 2:14,565,560...14,659,353 		JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:29,193,192...29,226,935
Ensembl chr 6:29,196,421...29,226,887 		JBrowse link
G ERCC5 ERCC excision repair 5, endonuclease involved_in ISO (PMID:26833090) UniProt PMID:26833090 NCBI chr22:52,339,011...52,372,618 JBrowse link
G EXD2 exonuclease 3'-5' domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:43,028,537...43,082,038
Ensembl chr 8:43,042,563...43,187,969 		JBrowse link
G FAN1 FANCD2 and FANCI associated nuclease 1 involved_in ISO (PMID:20603015), (PMID:20603016) UniProt PMID:20603015 PMID:20603016 NCBI chr 3:38,013,744...38,053,096
Ensembl chr 3:38,013,739...38,052,202 		JBrowse link
G FBH1 F-box DNA helicase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:30,047,994...30,095,761
Ensembl chr 2:30,048,567...30,095,696 		JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,201,540...13,233,028
Ensembl chr17:13,201,777...13,232,120 		JBrowse link
G H2AX H2A.X variant histone involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11934988) Ensembl
MGI		 PMID:11934988 GO_REF:0000107 NCBI chr 5:14,765,625...14,766,590
Ensembl chr 5:14,766,126...14,766,557 		JBrowse link
G HELQ helicase, POLQ like involved_in ISO (PMID:19995904) UniProt PMID:19995904 NCBI chr32:7,245,867...7,290,138
Ensembl chr32:7,245,230...7,290,014 		JBrowse link
G HTATSF1 HIV-1 Tat specific factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:106,848,455...106,866,540
Ensembl chr  X:106,848,455...106,866,540 		JBrowse link
G HUS1 HUS1 checkpoint clamp component involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:93,596...104,908
Ensembl chr16:93,626...125,597 		JBrowse link
G INIP INTS3 and NABP interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,137,101...67,154,443
Ensembl chr11:67,137,710...67,154,486 		JBrowse link
G INO80 INO80 complex ATPase subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:8,100,536...8,229,868
Ensembl chr30:8,101,934...8,202,025 		JBrowse link
G INTS3 integrator complex subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:43,325,522...43,361,669
Ensembl chr 7:43,326,315...43,361,362 		JBrowse link
G KASH5 KASH domain containing 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24062341) Ensembl
MGI		 PMID:24062341 GO_REF:0000107 NCBI chr 1:107,074,010...107,114,460
Ensembl chr 1:107,074,010...107,097,762 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr18:51,499,615...51,507,434
Ensembl chr18:51,499,938...51,576,699 		JBrowse link
G LOC119865601 checkpoint protein HUS1 involved_in IBA GO_Central GO_REF:0000033
G LOC119872575 integrator complex subunit 3 involved_in IEA Ensembl GO_REF:0000107
G LOC119876110 aurora kinase A and ninein-interacting protein-like involved_in IEA Ensembl GO_REF:0000107
G LOC485121 lysine-specific demethylase 4D acts_upstream_of_or_within ISO (PMID:24550317) MGI PMID:24550317 NCBI chr21:6,002,292...6,037,344
Ensembl chr21:5,987,723...6,004,783 		JBrowse link
G MBTD1 mbt domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:27,010,554...27,078,417
Ensembl chr 9:27,013,483...27,078,202 		JBrowse link
G MCM8 minichromosome maintenance 8 homologous recombination repair factor involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr24:15,850,602...15,893,452
Ensembl chr24:15,814,770...15,893,458 		JBrowse link
G MCM9 minichromosome maintenance 9 homologous recombination repair factor involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:58,746,637...58,862,550
Ensembl chr 1:58,767,159...58,859,282 		JBrowse link
G MEIOB meiosis specific with OB-fold involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:39,048,335...39,075,957
Ensembl chr 6:39,048,278...39,076,035 		JBrowse link
G MMS22L MMS22 like, DNA repair protein involved_in IEA
IBA		 InterPro
GO_Central
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:55,584,884...55,713,996
Ensembl chr12:55,588,888...55,713,341 		JBrowse link
G MORF4L1 mortality factor 4 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:58,127,152...58,149,709
Ensembl chr 3:58,127,669...58,193,005 		JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr21:6,448,909...6,528,185
Ensembl chr21:6,449,822...6,527,119 		JBrowse link
G NABP1 nucleic acid binding protein 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr37:2,157,357...2,163,812
Ensembl chr37:2,157,356...2,161,091 		JBrowse link
G NABP2 nucleic acid binding protein 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr10:546,964...551,360
Ensembl chr10:546,964...551,107 		JBrowse link
G NBN nibrin involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr29:35,416,093...35,477,569
Ensembl chr29:35,416,093...35,477,563 		JBrowse link
G NLE1 notchless homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:38,222,083...38,230,819
Ensembl chr 9:38,222,051...38,365,621 		JBrowse link
G NSMCE1 NSE1 homolog, SMC5-SMC6 complex component involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:19,330,815...19,363,240
Ensembl chr 6:19,330,843...19,363,239 		JBrowse link
G NSMCE2 NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase involved_in IEA
IBA		 InterPro
GO_Central
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr13:23,078,143...23,288,302
Ensembl chr13:23,078,173...23,288,304 		JBrowse link
G NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr38:2,157,109...2,188,543
Ensembl chr38:2,160,233...2,170,560 		JBrowse link
G PALB2 partner and localizer of BRCA2 involved_in IEA
IBA		 Ensembl
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:22,209,711...22,237,798
Ensembl chr 6:22,209,384...22,237,745 		JBrowse link
G POGZ pogo transposable element derived with ZNF domain involved_in
acts_upstream_of_or_within_positive_effect		 IEA
ISO		 (PMID:26721387) Ensembl
UniProt		 PMID:26721387 GO_REF:0000107 NCBI chr17:60,464,609...60,511,735
Ensembl chr17:60,465,230...60,511,934 		JBrowse link
G POLL DNA polymerase lambda involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:14,193,065...14,201,312
Ensembl chr28:14,193,067...14,201,334 		JBrowse link
G POLN DNA polymerase nu involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:61,946,295...62,104,112
Ensembl chr 3:61,962,193...62,102,264 		JBrowse link
G PPP4C protein phosphatase 4 catalytic subunit involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,085,048...18,092,861
Ensembl chr 6:18,085,116...18,092,854 		JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:6,883,612...6,985,291
Ensembl chr36:6,889,622...6,984,974 		JBrowse link
G RAD21L1 RAD21 cohesin complex component like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22711701) Ensembl
MGI		 PMID:22711701 GO_REF:0000107 NCBI chr24:19,741,398...19,771,675
Ensembl chr24:19,699,792...19,771,679 		JBrowse link
G RAD50 RAD50 double strand break repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:20,836,863...20,928,930
Ensembl chr11:20,836,879...20,928,819 		JBrowse link
G RAD51 RAD51 recombinase acts_upstream_of_or_within
involved_in		 ISO
IEA
ISS		 (PMID:15485900)
(PMID:15359272)
(PMID:16428451)		 RGD
MGI
Ensembl
InterPro
UniProt		 PMID:14755242 PMID:15359272 PMID:15485900 PMID:16428451 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 RGD:9831188 NCBI chr30:7,842,540...7,877,128
Ensembl chr30:7,842,540...7,877,606 		JBrowse link
G RAD51AP1 RAD51 associated protein 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr27:40,303,935...40,341,666
Ensembl chr27:40,303,992...40,341,526 		JBrowse link
G RAD51B RAD51 paralog B involved_in IEA
IBA		 InterPro
GO_Central
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:41,779,435...42,357,362
Ensembl chr 8:41,778,714...42,357,298 		JBrowse link
G RAD51C RAD51 paralog C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:33,289,675...33,347,411
Ensembl chr 9:33,289,742...33,326,405 		JBrowse link
G RAD51D RAD51 paralog D involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:38,242,178...38,259,788
Ensembl chr 9:38,222,051...38,365,621 		JBrowse link
G RAD52 RAD52 homolog, DNA repair protein involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:12379650) Ensembl
GO_Central
InterPro
MGI		 PMID:12379650 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr27:42,915,334...43,032,293
Ensembl chr27:42,915,634...42,951,323 		JBrowse link
G RAD54B RAD54 homolog B acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:16428451)
(PMID:19061978)		 MGI
GO_Central
Ensembl		 PMID:16428451 PMID:19061978 GO_REF:0000033 GO_REF:0000107 NCBI chr29:39,096,680...39,195,054
Ensembl chr29:39,098,098...39,195,112 		JBrowse link
G RAD54L RAD54 like involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19061978)
(PMID:16428451)		 Ensembl
MGI		 PMID:16428451 PMID:19061978 GO_REF:0000107 NCBI chr15:14,111,168...14,139,819
Ensembl chr15:14,111,157...14,139,301 		JBrowse link
G RBBP8 RB binding protein 8, endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:65,218,288...65,319,696
Ensembl chr 7:65,218,297...65,297,099 		JBrowse link
G REC8 REC8 meiotic recombination protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22711701) Ensembl
MGI		 PMID:22711701 GO_REF:0000107 NCBI chr 8:4,165,637...4,171,488
Ensembl chr 8:4,165,879...4,171,486 		JBrowse link
G RECQL RecQ like helicase involved_in IBA GO_Central GO_REF:0000033 NCBI chr27:25,590,326...25,636,304
Ensembl chr27:25,590,831...25,636,685 		JBrowse link
G RECQL4 RecQ like helicase 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:37,930,906...37,936,653
Ensembl chr13:37,930,621...37,936,753 		JBrowse link
G RECQL5 RecQ like helicase 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:4,902,753...4,940,442
Ensembl chr 9:4,903,477...4,940,436 		JBrowse link
G REV3L REV3 like, DNA directed polymerase zeta catalytic subunit involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:67,776,285...67,953,337
Ensembl chr12:67,756,924...67,953,553 		JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:38,271,419...38,346,103
Ensembl chr 9:38,222,051...38,365,621 		JBrowse link
G RFWD3 ring finger and WD repeat domain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:75,960,909...76,001,088
Ensembl chr 5:75,960,955...76,000,467 		JBrowse link
G RMI1 RecQ mediated genome instability 1 involved_in ISO (PMID:23543748) ComplexPortal PMID:23543748 NCBI chr 1:75,481,650...75,499,284
Ensembl chr 1:75,481,708...75,484,576 		JBrowse link
G RMI2 RecQ mediated genome instability 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,440,493...31,445,318
Ensembl chr 6:31,441,517...31,445,310 		JBrowse link
G RNF138 ring finger protein 138 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:57,521,416...57,554,793
Ensembl chr 7:57,523,595...57,556,005 		JBrowse link
G RNF169 ring finger protein 169 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:23,574,478...23,655,305
Ensembl chr21:23,579,370...23,655,290 		JBrowse link
G RPA1 replication protein A1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:15470499) Ensembl
GO_Central
MGI		 PMID:15470499 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:45,958,566...46,034,850
Ensembl chr 9:45,958,619...46,034,328 		JBrowse link
G RPA2 replication protein A2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:72,463,951...72,479,864
Ensembl chr 2:72,419,459...72,479,227 		JBrowse link
G RPA3 replication protein A3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:23,230,447...23,234,554
Ensembl chr11:2,893,352...2,893,717 		JBrowse link
G RPA3 involved_in IBA GO_Central GO_REF:0000033
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:25,623,997...25,676,336
Ensembl chr24:25,626,134...25,680,902 		JBrowse link
G SEM1 SEM1 26S proteasome subunit acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:15359272) MGI
GO_Central		 PMID:15359272 GO_REF:0000033 NCBI chr14:21,767,105...21,790,229 JBrowse link
G SFPQ splicing factor proline and glutamine rich acts_upstream_of_or_within ISO (PMID:20813759) MGI PMID:20813759 NCBI chr15:6,879,955...6,896,309
Ensembl chr15:6,880,065...6,888,004 		JBrowse link
G SFR1 SWI5 dependent homologous recombination repair protein 1 involved_in IEA
IBA		 InterPro
GO_Central
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr28:16,436,261...16,440,219
Ensembl chr28:16,436,377...16,439,742 		JBrowse link
G SLX1A SLX1 homolog A, structure-specific endonuclease subunit involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,171,190...18,174,577 JBrowse link
G SLX4 SLX4 structure-specific endonuclease subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:37,648,297...37,666,584
Ensembl chr 6:37,647,976...37,703,190 		JBrowse link
G SMC5 structural maintenance of chromosomes 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:87,192,988...87,285,678
Ensembl chr 1:87,194,867...87,285,606 		JBrowse link
G SMC6 structural maintenance of chromosomes 6 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:13,132,945...13,201,214
Ensembl chr17:13,133,236...13,201,759 		JBrowse link
G SPIDR scaffold protein involved in DNA repair involved_in ISO (PMID:23509288), (PMID:27967308), (PMID:34697795) UniProt PMID:23509288 PMID:27967308 PMID:34697795 NCBI chr35:79,188...503,687
Ensembl chr35:79,185...514,797 		JBrowse link
G SWI5 SWI5 homologous recombination repair protein involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:55,229,510...55,234,645
Ensembl chr 9:55,229,550...55,234,489 		JBrowse link
G SWSAP1 SWIM-type zinc finger 7 associated protein 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:49,951,633...49,953,281
Ensembl chr20:49,951,783...49,953,434 		JBrowse link
G TONSL tonsoku like, DNA repair protein involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr13:37,846,010...37,857,633
Ensembl chr13:37,846,149...37,857,668 		JBrowse link
G TOP3A DNA topoisomerase III alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:41,262,820...41,290,101
Ensembl chr 5:41,263,017...41,290,100 		JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:30,517,172...30,578,664
Ensembl chr23:30,516,125...30,578,108 		JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N acts_upstream_of ISO (PMID:17349954) HGNC-UCL PMID:17349954 NCBI chr10:41,470,073...41,470,738
Ensembl chr10:41,470,073...41,470,738 		JBrowse link
G WDR48 WD repeat domain 48 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:24001775) Ensembl
GO_Central
MGI		 PMID:24001775 GO_REF:0000033 GO_REF:0000107 NCBI chr23:8,716,598...8,766,242
Ensembl chr23:8,715,700...8,764,678 		JBrowse link
G WRN WRN RecQ like helicase involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:33,164,662...33,304,466
Ensembl chr16:33,167,364...33,304,625 		JBrowse link
G XRCC2 X-ray repair cross complementing 2 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:16777961) InterPro
GO_Central
MGI
Ensembl		 PMID:16777961 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr16:16,402,821...16,429,095
Ensembl chr16:16,402,933...16,429,037 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:71,441,732...71,452,922
Ensembl chr 8:71,442,429...71,449,408 		JBrowse link
G YY1 YY1 transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:68,539,511...68,572,796
Ensembl chr 8:68,539,353...68,568,058 		JBrowse link
G ZFYVE26 zinc finger FYVE-type containing 26 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 8:41,714,654...41,777,996
Ensembl chr 8:41,715,485...41,777,422 		JBrowse link
G ZMYND8 zinc finger MYND-type containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:34,322,364...34,466,044
Ensembl chr24:34,321,570...34,485,544 		JBrowse link
G ZSWIM7 zinc finger SWIM-type containing 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:39,868,086...39,883,693
Ensembl chr 5:39,868,123...39,882,557 		JBrowse link
DNA recombinase assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMC1 DNA meiotic recombinase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:26,228,662...26,265,377
Ensembl chr10:26,230,428...26,264,820 		JBrowse link
G RAD51 RAD51 recombinase involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr30:7,842,540...7,877,128
Ensembl chr30:7,842,540...7,877,606 		JBrowse link
G RAD52 RAD52 homolog, DNA repair protein involved_in IEA InterPro GO_REF:0000002 NCBI chr27:42,915,334...43,032,293
Ensembl chr27:42,915,634...42,951,323 		JBrowse link
double-strand break repair via break-induced replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC45 cell division cycle 45 involved_in IBA GO_Central GO_REF:0000033 NCBI chr26:29,707,523...29,738,599
Ensembl chr26:29,707,564...29,739,252 		JBrowse link
G CDC7 cell division cycle 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:57,336,165...57,362,478
Ensembl chr 6:57,337,407...57,362,757 		JBrowse link
G GINS2 GINS complex subunit 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:66,982,033...66,997,115
Ensembl chr 5:66,982,137...67,000,338 		JBrowse link
G GINS4 GINS complex subunit 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:24,055,720...24,068,469
Ensembl chr16:24,056,963...24,069,052 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:1,682,928...1,702,689
Ensembl chr20:1,682,886...1,702,366 		JBrowse link
G MCM3 minichromosome maintenance complex component 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:19,924,017...19,945,576
Ensembl chr12:19,920,210...19,945,605 		JBrowse link
G MCM4 minichromosome maintenance complex component 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr29:244,634...261,154
Ensembl chr29:244,656...260,991 		JBrowse link
G MCM5 minichromosome maintenance complex component 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:28,721,421...28,738,457
Ensembl chr10:28,721,660...28,738,390 		JBrowse link
G MCM6 minichromosome maintenance complex component 6 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:38,627,154...38,660,312
Ensembl chr19:38,627,183...38,660,280 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:9,492,654...9,499,846
Ensembl chr 6:9,492,573...9,499,855 		JBrowse link
G MCMDC2 minichromosome maintenance domain containing 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr29:16,424,088...16,462,094
Ensembl chr29:16,426,318...16,460,599 		JBrowse link
G MUS81 MUS81 structure-specific endonuclease subunit involved_in IEA
IBA		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr18:51,396,980...51,404,563
Ensembl chr18:51,396,980...51,402,534 		JBrowse link
double-strand break repair via synthesis-dependent strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FANCM FA complementation group M involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:22,561,862...22,625,077
Ensembl chr 8:22,562,147...22,623,994 		JBrowse link
G HELQ helicase, POLQ like involved_in ISO (PMID:34937945) UniProt PMID:34937945 NCBI chr32:7,245,867...7,290,138
Ensembl chr32:7,245,230...7,290,014 		JBrowse link
G RAD54L RAD54 like involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:14,111,168...14,139,819
Ensembl chr15:14,111,157...14,139,301 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:71,441,732...71,452,922
Ensembl chr 8:71,442,429...71,449,408 		JBrowse link
late meiotic recombination nodule assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MCMDC2 minichromosome maintenance domain containing 2 acts_upstream_of_or_within ISO (PMID:27760146) MGI PMID:27760146 NCBI chr29:16,424,088...16,462,094
Ensembl chr29:16,426,318...16,460,599 		JBrowse link
meiotic DNA recombinase assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAD51C RAD51 paralog C involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:33,289,675...33,347,411
Ensembl chr 9:33,289,742...33,326,405 		JBrowse link
meiotic recombination nodule assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MCMDC2 minichromosome maintenance domain containing 2 acts_upstream_of_or_within ISO (PMID:27760146) MGI PMID:27760146 NCBI chr29:16,424,088...16,462,094
Ensembl chr29:16,426,318...16,460,599 		JBrowse link
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G C1QBP complement C1q binding protein involved_in ISO (PMID:31353207) UniProt PMID:31353207 NCBI chr 5:31,354,665...31,359,672
Ensembl chr 5:31,354,723...31,359,469 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:35,511,920...35,528,759
Ensembl chr12:35,512,860...35,528,596 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in ISO (PMID:28512243) UniProt PMID:28512243 NCBI chr24:20,333,593...20,390,341 JBrowse link
G FANCB FA complementation group B acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:25520194) MGI
GO_Central		 PMID:25520194 GO_REF:0000033 NCBI chr  X:10,690,826...11,140,838
Ensembl chr  X:11,095,200...11,141,029 		JBrowse link
G FBH1 F-box DNA helicase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:30,047,994...30,095,761
Ensembl chr 2:30,048,567...30,095,696 		JBrowse link
G HELB DNA helicase B involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr10:8,766,023...8,797,055
Ensembl chr10:8,765,617...8,798,092 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,499,615...51,507,434
Ensembl chr18:51,499,938...51,576,699 		JBrowse link
G KLHL15 kelch like family member 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:19,617,629...19,651,076
Ensembl chr  X:19,618,569...19,650,728 		JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:84,539,724...84,549,402
Ensembl chr 2:84,545,226...84,549,356 		JBrowse link
G MAGEF1 MAGE family member F1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:17,543,381...17,545,089
Ensembl chr34:17,543,906...17,544,868 		JBrowse link
G PARPBP PARP1 binding protein involved_in IEA
IBA		 InterPro
Ensembl
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr15:40,972,098...41,039,044
Ensembl chr15:40,976,598...41,036,068 		JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:22,165,338...22,176,847
Ensembl chr 6:22,165,338...22,176,441 		JBrowse link
G POLQ DNA polymerase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:24,713,174...24,837,113
Ensembl chr33:24,714,086...24,837,402 		JBrowse link
G RADX RPA1 related single stranded DNA binding protein, X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:80,146,335...80,234,732
Ensembl chr  X:80,146,040...80,235,739 		JBrowse link
G RECQL5 RecQ like helicase 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25520194) Ensembl
MGI		 PMID:25520194 GO_REF:0000107 NCBI chr 9:4,902,753...4,940,442
Ensembl chr 9:4,903,477...4,940,436 		JBrowse link
G RIF1 replication timing regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:52,661,278...52,711,969
Ensembl chr19:52,661,155...52,709,279 		JBrowse link
G RMI2 RecQ mediated genome instability 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:31,440,493...31,445,318
Ensembl chr 6:31,441,517...31,445,310 		JBrowse link
G SENP3 SUMO specific peptidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,485,738...32,493,225
Ensembl chr 5:32,484,572...32,500,805 		JBrowse link
G SHLD1 shieldin complex subunit 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr24:15,957,863...16,037,336
Ensembl chr24:15,957,852...16,038,008 		JBrowse link
G SHLD2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 4:34,665,111...34,740,645
Ensembl chr 4:34,688,245...34,763,705 		JBrowse link
G SHLD3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) UniProt PMID:29656893
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:69,359,286...69,505,067
Ensembl chr 7:69,358,447...69,621,067 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:10,263,650...10,362,646
Ensembl chr30:10,263,650...10,336,134 		JBrowse link
G UBQLN4 ubiquilin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:41,764,209...41,778,457
Ensembl chr 7:41,764,253...41,777,002 		JBrowse link
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTB actin beta involved_in ISO (PMID:27153538) ComplexPortal PMID:27153538 NCBI chr 6:12,421,006...12,424,449
Ensembl chr 6:12,418,932...12,462,845 		JBrowse link
G ACTL6A actin like 6A involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:12,922,506...12,988,334
Ensembl chr34:12,960,699...12,987,962 		JBrowse link
G ACTR2 actin related protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,696,068...64,733,027
Ensembl chr10:64,696,111...64,730,553 		JBrowse link
G ARID2 AT-rich interaction domain 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:8,411,092...8,579,735
Ensembl chr27:8,412,377...8,579,882 		JBrowse link
G BLM BLM RecQ like helicase acts_upstream_of_or_within ISO (PMID:25520194) MGI PMID:25520194 NCBI chr 3:53,408,120...53,506,728
Ensembl chr 3:53,408,217...53,473,146 		JBrowse link
G BRD8 bromodomain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:25,793,375...25,825,868
Ensembl chr11:25,793,668...25,825,726 		JBrowse link
G CREBBP CREB binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:37,410,201...37,536,688
Ensembl chr 6:37,409,930...37,534,176 		JBrowse link
G DMAP1 DNA methyltransferase 1 associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:16,077,164...16,085,666
Ensembl chr15:16,077,206...16,085,687 		JBrowse link
G EFNB3 ephrin B3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,588,062...32,592,390
Ensembl chr 5:32,574,134...32,594,333 		JBrowse link
G EP400 E1A binding protein p400 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:848,028...951,135
Ensembl chr26:848,016...951,171 		JBrowse link
G EPC1 enhancer of polycomb homolog 1 involved_in ISO (PMID:27153538) ComplexPortal PMID:27153538 NCBI chr 2:14,566,177...14,659,774
Ensembl chr 2:14,565,560...14,659,353 		JBrowse link
G EPC2 enhancer of polycomb homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:50,356,490...50,484,405
Ensembl chr19:50,416,340...50,482,878 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:1,358,383...1,432,276
Ensembl chr28:1,361,107...1,427,162 		JBrowse link
G FANCB FA complementation group B acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:25520194) MGI
GO_Central		 PMID:25520194 GO_REF:0000033 NCBI chr  X:10,690,826...11,140,838
Ensembl chr  X:11,095,200...11,141,029 		JBrowse link
G FUS FUS RNA binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,059,904...17,071,227
Ensembl chr 6:17,060,061...17,071,178 		JBrowse link
G HDGFL2 HDGF like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,204,861...55,224,543
Ensembl chr20:55,204,868...55,224,528 		JBrowse link
G HELQ helicase, POLQ like involved_in ISO (PMID:24005329) UniProt PMID:24005329 NCBI chr32:7,245,867...7,290,138
Ensembl chr32:7,245,230...7,290,014 		JBrowse link
G ING3 inhibitor of growth family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:59,067,282...59,093,399
Ensembl chr14:59,067,351...59,092,976 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,499,615...51,507,434
Ensembl chr18:51,499,938...51,576,699 		JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISO (PMID:31609975)
(PMID:25936915)		 UniProt PMID:25936915 PMID:31609975 NCBI chr12:35,434,123...35,435,679
Ensembl chr12:35,434,123...35,468,943 		JBrowse link
G MBTD1 mbt domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:27,010,554...27,078,417
Ensembl chr 9:27,013,483...27,078,202 		JBrowse link
G MEAF6 MYST/Esa1 associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:4,944,059...4,971,573
Ensembl chr15:4,943,430...4,964,391 		JBrowse link
G MORF4L1 mortality factor 4 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:58,127,152...58,149,709
Ensembl chr 3:58,127,669...58,193,005 		JBrowse link
G MORF4L2 mortality factor 4 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:77,084,940...77,097,900
Ensembl chr  X:77,085,599...77,086,465 		JBrowse link
G MRGBP MRG domain binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:46,634,580...46,637,222
Ensembl chr24:46,634,668...46,637,354 		JBrowse link
G MRNIP MRN complex interacting protein involved_in ISO (PMID:27568553) UniProt PMID:27568553 NCBI chr11:1,834,148...1,859,601
Ensembl chr11:1,833,967...1,859,347 		JBrowse link
G OOEP oocyte expressed protein involved_in ISS UniProt GO_REF:0000024 NCBI chr12:35,431,562...35,449,540
Ensembl chr12:35,448,015...35,449,511 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:63,727,905...63,863,599
Ensembl chr10:63,729,604...63,743,303 		JBrowse link
G PIAS4 protein inhibitor of activated STAT 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,529,841...55,553,604
Ensembl chr20:55,524,443...55,553,525 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in ISO (PMID:15741314), (PMID:29651020) UniProt PMID:15741314 PMID:29651020 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075 		JBrowse link
G RAD51AP1 RAD51 associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:40,303,935...40,341,666
Ensembl chr27:40,303,992...40,341,526 		JBrowse link
G RNF126 ring finger protein 126 involved_in ISO (PMID:36563124) UniProt PMID:36563124 NCBI chr20:57,890,333...57,899,364
Ensembl chr20:57,891,413...57,898,863 		JBrowse link
G RNF8 ring finger protein 8 involved_in ISO (PMID:23115235) UniProt PMID:23115235 NCBI chr12:6,380,365...6,415,407
Ensembl chr12:6,292,459...6,415,382 		JBrowse link
G RUVBL1 RuvB like AAA ATPase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:2,095,807...2,137,528
Ensembl chr20:2,095,786...2,137,579 		JBrowse link
G RUVBL2 RuvB like AAA ATPase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,384,328...107,400,849
Ensembl chr 1:107,384,342...107,400,505 		JBrowse link
G SKP2 S-phase kinase associated protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:72,352,966...72,386,469
Ensembl chr 4:72,352,986...72,386,307 		JBrowse link
G TIMELESS timeless circadian regulator involved_in ISO (PMID:26344098), (PMID:30356214) UniProt PMID:26344098 PMID:30356214 NCBI chr10:671,829...701,152
Ensembl chr10:671,269...687,016 		JBrowse link
G TRRAP transformation/transcription domain associated protein involved_in ISO (PMID:27153538) ComplexPortal PMID:27153538 NCBI chr 6:10,519,734...10,635,175
Ensembl chr 6:10,519,711...10,632,776 		JBrowse link
G VPS72 vacuolar protein sorting 72 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:60,239,299...60,252,323
Ensembl chr17:60,239,395...60,252,280 		JBrowse link
G WAS WASP actin nucleation promoting factor involved_in ISO (PMID:29925947) UniProt PMID:29925947 NCBI chr  X:41,882,240...41,890,053
Ensembl chr  X:41,882,875...41,890,058 		JBrowse link
G WDR48 WD repeat domain 48 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:8,716,598...8,766,242
Ensembl chr23:8,715,700...8,764,678 		JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,574,153...32,586,222
Ensembl chr 5:32,574,134...32,594,333 		JBrowse link
G YEATS4 YEATS domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:11,364,435...11,382,340
Ensembl chr10:11,364,553...11,382,645 		JBrowse link
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHEK1 checkpoint kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:8,878,511...8,910,626
Ensembl chr 5:8,879,147...8,907,669 		JBrowse link
G FIGNL1 fidgetin like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:1,788,063...1,792,900
Ensembl chr18:1,788,801...1,790,831 		JBrowse link
G KDM1A lysine demethylase 1A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24217620) MGI
Ensembl		 PMID:24217620 GO_REF:0000107 NCBI chr 2:76,313,742...76,375,716
Ensembl chr 2:76,156,434...76,375,632 		JBrowse link
G PPP4C protein phosphatase 4 catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,085,048...18,092,861
Ensembl chr 6:18,085,116...18,092,854 		JBrowse link
G PPP4R2 protein phosphatase 4 regulatory subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:19,116,122...19,166,927
Ensembl chr20:19,118,124...19,167,264 		JBrowse link
G RAD51 RAD51 recombinase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr30:7,842,540...7,877,128
Ensembl chr30:7,842,540...7,877,606 		JBrowse link
G RAD51AP1 RAD51 associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:40,303,935...40,341,666
Ensembl chr27:40,303,992...40,341,526 		JBrowse link
G RPA2 replication protein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:72,463,951...72,479,864
Ensembl chr 2:72,419,459...72,479,227 		JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 involved_in IEA
IBA		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr24:47,219,977...47,248,791 JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:41,675,539...41,800,697
Ensembl chr20:41,675,599...41,800,612 		JBrowse link
G SHLD2 shieldin complex subunit 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:34,665,111...34,740,645
Ensembl chr 4:34,688,245...34,763,705 		JBrowse link
G SHLD3 shieldin complex subunit 3 involved_in IEA InterPro GO_REF:0000002
G SIRT6 sirtuin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,412,989...55,424,944
Ensembl chr20:55,412,646...55,424,944 		JBrowse link
G SPIDR scaffold protein involved in DNA repair involved_in ISO (PMID:23754376) UniProt PMID:23754376 NCBI chr35:79,188...503,687
Ensembl chr35:79,185...514,797 		JBrowse link
G TERF2IP TERF2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:75,164,410...75,172,959
Ensembl chr 5:75,165,191...75,172,838 		JBrowse link
G TEX15 testis expressed 15, meiosis and synapsis associated involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:18283110) InterPro
GO_Central
MGI		 PMID:18283110 GO_REF:0000002 GO_REF:0000033 NCBI chr16:33,423,546...33,517,458
Ensembl chr16:33,423,876...33,515,452 		JBrowse link
G USP51 ubiquitin specific peptidase 51 involved_in ISO (PMID:27083998) UniProt PMID:27083998 NCBI chr  X:47,055,226...47,059,552 JBrowse link
G ZNF365 zinc finger protein 365 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:14,297,652...14,429,634
Ensembl chr 4:14,311,302...14,331,568 		JBrowse link
replication-born double-strand break repair via sister chromatid exchange term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase acts_upstream_of_or_within ISO (PMID:25597246) MGI PMID:25597246 NCBI chr 3:53,408,120...53,506,728
Ensembl chr 3:53,408,217...53,473,146 		JBrowse link
G FANCB FA complementation group B acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:25520194) MGI
GO_Central		 PMID:25520194 GO_REF:0000033 NCBI chr  X:10,690,826...11,140,838
Ensembl chr  X:11,095,200...11,141,029 		JBrowse link
G NIPBL NIPBL cohesin loading factor involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:71,583,118...71,780,986
Ensembl chr 4:71,583,732...71,780,852 		JBrowse link
G RAD21 RAD21 cohesin complex component involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:16,337,563...16,368,041
Ensembl chr13:16,338,972...16,368,035 		JBrowse link
G RAD21L1 RAD21 cohesin complex component like 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr24:19,741,398...19,771,675
Ensembl chr24:19,699,792...19,771,679 		JBrowse link
G RAD51 RAD51 recombinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22778135) Ensembl
MGI		 PMID:22778135 GO_REF:0000107 NCBI chr30:7,842,540...7,877,128
Ensembl chr30:7,842,540...7,877,606 		JBrowse link
G RECQL5 RecQ like helicase 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25520194) Ensembl
MGI		 PMID:25520194 GO_REF:0000107 NCBI chr 9:4,902,753...4,940,442
Ensembl chr 9:4,903,477...4,940,436 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:111,548,719...111,571,816
Ensembl chr 1:111,548,719...111,571,816 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22103
    cellular process 21633
      cellular response to stimulus 7934
        cellular response to stress 2004
          DNA damage response 851
            DNA repair 540
              double-strand break repair 306
                double-strand break repair via homologous recombination 184
                  DNA synthesis involved in double-strand break repair via homologous recombination 0
                  double-strand break repair via break-induced replication + 12
                  double-strand break repair via synthesis-dependent strand annealing + 9
                  double-strand break repair via transcription-associated homologous recombination 0
                  negative regulation of double-strand break repair via homologous recombination + 25
                  positive regulation of double-strand break repair via homologous recombination 44
                  regulation of double-strand break repair via homologous recombination + 82
                  replication-born double-strand break repair via sister chromatid exchange 8
Path 2
Term Annotations click to browse term
  biological_process 22103
    cellular process 21633
      metabolic process 15381
        primary metabolic process 13982
          nucleobase-containing compound metabolic process 9612
            nucleic acid metabolic process 9019
              DNA metabolic process 932
                DNA repair 540
                  recombinational repair 187
                    double-strand break repair via homologous recombination 184
                      DNA synthesis involved in double-strand break repair via homologous recombination 0
                      double-strand break repair via break-induced replication + 12
                      double-strand break repair via synthesis-dependent strand annealing + 9
                      double-strand break repair via transcription-associated homologous recombination 0
                      negative regulation of double-strand break repair via homologous recombination + 25
                      positive regulation of double-strand break repair via homologous recombination 44
                      regulation of double-strand break repair via homologous recombination + 82
                      replication-born double-strand break repair via sister chromatid exchange 8
paths to the root