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ONTOLOGY REPORT - ANNOTATIONS

Term:telomere maintenance
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Accession:GO:0000723 term browser browse the term
Definition:Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
Synonyms:related_synonym: regulation of telomere length


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telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor acts_upstream_of_or_within ISO (PMID:15181449) RGD PMID:15181449 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Actl6a actin-like 6A involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 2:115,492,374...115,508,401
Ensembl chr 2:115,492,285...115,508,401 		JBrowse link
G Actr5 actin related protein 5 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 3:147,282,461...147,296,110
Ensembl chr 3:147,282,624...147,296,110 		JBrowse link
G Actr8 actin related protein 8 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr16:5,164,131...5,186,353
Ensembl chr16:5,164,129...5,178,577 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 involved_in ISO (PMID:24703901) RGD PMID:24703901 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Atm ATM serine/threonine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Blm BLM RecQ like helicase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:109558|MGI:109635 (MGI:3055614|PMID:15367665)		 RGD PMID:15367665 PMID:21873635 MGI:3055614, RGD:13792537 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Ccne1 cyclin E1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1329034 (MGI:5698037|PMID:24586195)		 Ensembl
RGD		 PMID:24586195 GO_REF:0000107 MGI:5698037 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccne2 cyclin E2 acts_upstream_of_or_within ISO MGI:88316 (MGI:5698037|PMID:24586195) RGD PMID:24586195 MGI:5698037 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in ISO (PMID:19854131) RGD PMID:19854131 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298 		JBrowse link
G Dclre1b DNA cross-link repair 1B involved_in ISO
IBA
ISS		 (PMID:20655466)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:20655466 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423 		JBrowse link
G Dclre1c DNA cross-link repair 1C acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (MGI:3514096|PMID:12615897)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:12615897 PMID:21873635 GO_REF:0000107 MGI:3514096, RGD:13792537 NCBI chr17:74,775,828...74,810,089
Ensembl chr17:74,776,935...74,809,186 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO UniProtKB:Q15554 (PMID:14690602), (PMID:17055345) RGD PMID:14690602 PMID:17055345 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Fbxo4 F-box protein 4 involved_in ISO (PMID:16275645) RGD PMID:16275645 NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B acts_upstream_of_or_within ISO MGI:3028843 (MGI:3027215|PMID:14701760) RGD PMID:14701760 MGI:3027215 NCBI chr20:3,870,765...3,873,221 JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442 		JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911 		JBrowse link
G Ino80b INO80 complex subunit B involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 4:115,627,907...115,631,069
Ensembl chr 4:115,627,908...115,631,456 		JBrowse link
G Ino80c INO80 complex subunit C involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr18:15,378,764...15,398,574
Ensembl chr18:15,378,770...15,393,403 		JBrowse link
G Ino80d INO80 complex subunit D involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 9:64,447,075...64,514,013
Ensembl chr 9:64,457,165...64,515,242 		JBrowse link
G Ino80e INO80 complex subunit E involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 1:181,461,406...181,472,059
Ensembl chr 1:181,461,408...181,472,469 		JBrowse link
G Lto1 LTO1 maturation factor of ABCE1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:200,074,247...200,080,951
Ensembl chr 1:200,074,253...200,088,061 		JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Nbn nibrin involved_in ISO
IEA
ISS		 (PMID:11448772)
GO_REF:0000002
GO_REF:0000024		 RGD
InterPro
UniProt		 PMID:11448772 GO_REF:0000002 GO_REF:0000024 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 8:29,831,802...29,863,360
Ensembl chr 8:29,831,812...29,863,359 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 acts_upstream_of_or_within ISO MGI:1857862 (MGI:2656673|PMID:12707040) RGD PMID:12707040 MGI:2656673 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Parp3 poly (ADP-ribose) polymerase family, member 3 acts_upstream_of_or_within ISO (PMID:21270334) RGD PMID:21270334 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782 		JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1857113 (MGI:3034120|PMID:15010310)		 RGD PMID:15010310 PMID:21873635 MGI:3034120, RGD:13792537 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in TAS
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:10908350 GO_REF:0000002, RGD:68816 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rad51d RAD51 paralog D involved_in ISO
IBA		 (PMID:15109494)
UniProtKB:P02340 (MGI:5705225|PMID:15109494)
PMID:21873635		 RGD PMID:15109494 PMID:21873635 MGI:5705225, RGD:13792537 NCBI chr10:67,805,720...67,824,452
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Recql4 RecQ like helicase 4 involved_in ISO
IBA		 (PMID:22039056)
PMID:21873635		 RGD PMID:22039056 PMID:21873635 RGD:13792537 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:67,740,711...67,803,694
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in IBA
ISO		 PMID:21873635
(MGI:5584328|PMID:24735877)		 RGD PMID:24735877 PMID:21873635 MGI:5584328, RGD:13792537 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617 		JBrowse link
G Rpa1 replication protein A1 involved_in ISO (PMID:17959650) RGD PMID:17959650 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949 		JBrowse link
G Rpa2 replication protein A2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17959650)		 UniProt
RGD		 PMID:17959650 GO_REF:0000024 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA
ISS		 (PMID:23453664)
MGI:3052235 (MGI:3046595|PMID:15210109)
GO_REF:0000104
GO_REF:0000024		 RGD
UniProt		 PMID:15210109 PMID:23453664 GO_REF:0000024 GO_REF:0000104 MGI:3046595 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 1:95,902,014...95,915,364
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:15767676) RGD PMID:15767676 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISS
ISO		 GO_REF:0000024
(PMID:19854130)		 UniProt
RGD		 PMID:19854130 GO_REF:0000024 NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531 		JBrowse link
G Terc telomerase RNA component acts_upstream_of_or_within ISO MGI:109635|MGI:1328362|MGI:1857930 (MGI:3050262|PMID:15235603), (MGI:3055614|PMID:15367665), (MGI:3700621|PMID:17145779) RGD PMID:15235603 PMID:15367665 PMID:17145779 MGI:3050262 MGI:3055614 MGI:3700621 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO (PMID:24415760) RGD PMID:24415760 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in
acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:20655466)
MGI:3619525 (MGI:3615734|PMID:15968270)
(MGI:3034120|PMID:15010310)		 RGD PMID:15010310 PMID:15968270 PMID:20655466 MGI:3034120 MGI:3615734 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Tfpt TCF3 fusion partner involved_in ISO
IEA		 (MGI:5638510|PMID:23979016)
GO_REF:0000107		 RGD
Ensembl		 PMID:23979016 GO_REF:0000107 MGI:5638510 NCBI chr 1:65,587,855...65,597,407
Ensembl chr 1:65,582,359...65,611,689 		JBrowse link
G Tnks2 tankyrase 2 NOT|acts_upstream_of_or_within ISO MGI:3621819|MGI:3621924 (MGI:3619771|PMID:16507985), (MGI:3619772|PMID:16507984) RGD PMID:16507984 PMID:16507985 MGI:3619771 MGI:3619772 NCBI chr 1:234,567,888...234,621,079
Ensembl chr 1:234,567,858...234,621,079 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Wrn WRN RecQ like helicase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:109558|MGI:1328362|MGI:2156622 (MGI:2656673|PMID:12707040), (MGI:3050262|PMID:15235603), (MGI:3055614|PMID:15367665)
(PMID:18212065)		 RGD PMID:12707040 PMID:15235603 PMID:15367665 PMID:18212065 PMID:21873635 MGI:2656673 MGI:3050262 MGI:3055614, RGD:13792537 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
G Yy1 YY1 transcription factor involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 6:127,706,739...127,731,907
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
G Zfp365 zinc finger protein 365 involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
PMID:21873635
(MGI:5529874|PMID:23776040)		 UniProt
Ensembl
RGD		 PMID:23776040 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5529874, RGD:13792537 NCBI chr20:20,666,240...20,689,734
Ensembl chr20:20,666,240...20,691,238 		JBrowse link
G Zfp827 zinc finger protein 827 involved_in ISO (PMID:25150861) RGD PMID:25150861 NCBI chr19:28,720,568...28,887,381
Ensembl chr19:28,721,021...28,887,191 		JBrowse link
mitotic telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcna proliferating cell nuclear antigen involved_in ISO UniProtKB:Q0VGM9 (MGI:5522574|PMID:24115439) RGD PMID:24115439 MGI:5522574 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5522574|PMID:24115439) RGD PMID:24115439 MGI:5522574 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
negative regulation of protection from non-homologous end joining at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO (MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:3758502 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in ISO (MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:3758502 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
negative regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IBA		 (PMID:25620558)
(MGI:5522574|PMID:24115439), (MGI:5645200|PMID:22579284)
PMID:21873635		 RGD PMID:22579284 PMID:24115439 PMID:25620558 PMID:21873635 MGI:5522574 MGI:5645200, RGD:13792537 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:15507207) RGD PMID:15507207 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:19581589) RGD PMID:19581589 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
negative regulation of telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:17694070) RGD PMID:17694070 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Nbn nibrin involved_in IEA
ISO		 GO_REF:0000107
(PMID:17694070)		 Ensembl
RGD		 PMID:17694070 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO
IEA		 (PMID:17694070)
GO_REF:0000107		 RGD
Ensembl		 PMID:17694070 GO_REF:0000107 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor involved_in ISO (PMID:12676087) RGD PMID:12676087 NCBI chr10:59,786,258...60,014,395
Ensembl chr10:59,786,258...60,014,395 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:24270157) RGD PMID:24270157 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
negative regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 acts_upstream_of_or_within ISO (MGI:2656398|PMID:12676566) RGD PMID:12676566 MGI:2656398 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984 		JBrowse link
negative regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA		 (PMID:15507207)
(MGI:5883205|PMID:24120135)
PMID:21873635		 RGD PMID:15507207 PMID:24120135 PMID:21873635 MGI:5883205, RGD:13792537 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IEA
IBA		 UniProtKB:Q9NUX5 (PMID:15181449), (PMID:15380063)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:15181449 PMID:15380063 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in ISO (PMID:22763445) RGD PMID:22763445 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298 		JBrowse link
G Dcp2 decapping mRNA 2 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557 		JBrowse link
G Exosc10 exosome component 10 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940 		JBrowse link
G Gnl3l G protein nucleolar 3 like involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr  X:19,961,277...19,994,454
Ensembl chr  X:19,958,603...19,994,508 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO
IEA		 (PMID:23935072)
GO_REF:0000107		 RGD
Ensembl		 PMID:23935072 GO_REF:0000107 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(PMID:18082603)		 Ensembl
RGD		 PMID:18082603 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Nat10 N-acetyltransferase 10 involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr 3:90,111,643...90,151,644
Ensembl chr 3:90,111,645...90,149,927 		JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:23657261) RGD PMID:23657261 NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200 		JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 involved_in ISO
IEA		 (PMID:11701125), (PMID:21119197)
GO_REF:0000107		 RGD
Ensembl		 PMID:11701125 PMID:21119197 GO_REF:0000107 NCBI chr15:38,098,027...38,157,143
Ensembl chr15:38,097,886...38,157,140 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:19567472) RGD PMID:19567472 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO UniProtKB:Q96AP0 (PMID:15181449) RGD PMID:15181449 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISO
IEA		 (PMID:22763445)
GO_REF:0000107		 RGD
Ensembl		 PMID:22763445 GO_REF:0000107 NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531 		JBrowse link
G Ten1 TEN1 subunit of CST complex involved_in IBA
ISO		 PMID:21873635
(PMID:22763445)		 RGD PMID:22763445 PMID:21873635 RGD:13792537 NCBI chr10:101,431,328...101,455,105
Ensembl chr10:101,431,328...101,453,052 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537 		JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO UniProtKB:O14746 (PMID:11971978) RGD PMID:11971978 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:11971978), (PMID:17055345) RGD PMID:11971978 PMID:17055345 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 involved_in ISO (PMID:10581025), (PMID:15133513) RGD PMID:10581025 PMID:15133513 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984 		JBrowse link
negative regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:18812185) RGD PMID:18812185 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO (PMID:15044100) RGD PMID:15044100 NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO (MGI:5705431|PMID:26586427) RGD PMID:26586427 MGI:5705431 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Tnks tankyrase involved_in ISO (PMID:25939383) RGD PMID:25939383 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
G Tnks2 tankyrase 2 involved_in ISO (PMID:25939383) RGD PMID:25939383 NCBI chr 1:234,567,888...234,621,079
Ensembl chr 1:234,567,858...234,621,079 		JBrowse link
negative regulation of telomeric D-loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA		 (PMID:15200954)
PMID:21873635		 RGD PMID:15200954 PMID:21873635 RGD:13792537 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA		 (PMID:15200954)
PMID:21873635		 RGD PMID:15200954 PMID:21873635 RGD:13792537 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
positive regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
positive regulation of telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D involved_in ISO (MGI:5438900|PMID:22633954) RGD PMID:22633954 MGI:5438900 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk15 mitogen-activated protein kinase 15 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052 		JBrowse link
G Nabp2 nucleic acid binding protein 2 involved_in ISO
IEA		 (PMID:25589350)
GO_REF:0000107
(MGI:5629774|PMID:25589350)		 RGD
Ensembl		 PMID:25589350 GO_REF:0000107 MGI:5629774 NCBI chr 7:830,949...836,551
Ensembl chr 7:830,949...838,027 		JBrowse link
G Nek2 NIMA-related kinase 2 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051 		JBrowse link
G Nek7 NIMA-related kinase 7 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920 		JBrowse link
G Prkcq protein kinase C, theta involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:23959892) RGD PMID:23959892 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Tnks tankyrase involved_in ISO
IBA		 (PMID:21531765), (PMID:25939383)
PMID:21873635		 RGD PMID:21531765 PMID:25939383 PMID:21873635 RGD:13792537 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
G Tnks2 tankyrase 2 involved_in ISO
IBA		 (PMID:21531765), (PMID:25939383)
PMID:21873635		 RGD PMID:21531765 PMID:25939383 PMID:21873635 RGD:13792537 NCBI chr 1:234,567,888...234,621,079
Ensembl chr 1:234,567,858...234,621,079 		JBrowse link
positive regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in ISO
IEA
ISS		 (MGI:4454526|PMID:20110566)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20110566 GO_REF:0000024 GO_REF:0000107 MGI:4454526 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:22238380) RGD PMID:22238380 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Gnl3 G protein nucleolar 3 involved_in ISO (PMID:22641345) RGD PMID:22641345 NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in ISO
IEA		 (PMID:16374507)
GO_REF:0000107		 RGD
Ensembl		 PMID:16374507 GO_REF:0000107 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Nbn nibrin involved_in IEA
ISO		 GO_REF:0000107
(PMID:16374507)		 Ensembl
RGD		 PMID:16374507 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:26119943)
(PMID:22641345)		 RGD PMID:22641345 PMID:26119943 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in ISO (PMID:23426265) RGD PMID:23426265 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO
IEA		 (PMID:16374507)
GO_REF:0000107		 RGD
Ensembl		 PMID:16374507 GO_REF:0000107 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:23201774), (PMID:25819580) RGD PMID:23201774 PMID:25819580 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
G Terf2 telomeric repeat binding factor 2 acts_upstream_of_or_within
involved_in		 ISO MGI:3619525 (MGI:3615734|PMID:15968270)
(PMID:24012755)		 RGD PMID:15968270 PMID:24012755 MGI:3615734 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
positive regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actl6a actin-like 6A involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 2:115,492,374...115,508,401
Ensembl chr 2:115,492,285...115,508,401 		JBrowse link
G Actr5 actin related protein 5 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 3:147,282,461...147,296,110
Ensembl chr 3:147,282,624...147,296,110 		JBrowse link
G Actr8 actin related protein 8 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr16:5,164,131...5,186,353
Ensembl chr16:5,164,129...5,178,577 		JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911 		JBrowse link
G Ino80b INO80 complex subunit B involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 4:115,627,907...115,631,069
Ensembl chr 4:115,627,908...115,631,456 		JBrowse link
G Ino80c INO80 complex subunit C involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr18:15,378,764...15,398,574
Ensembl chr18:15,378,770...15,393,403 		JBrowse link
G Ino80d INO80 complex subunit D involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 9:64,447,075...64,514,013
Ensembl chr 9:64,457,165...64,515,242 		JBrowse link
G Ino80e INO80 complex subunit E involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 1:181,461,406...181,472,059
Ensembl chr 1:181,461,408...181,472,469 		JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685 		JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 8:29,831,802...29,863,360
Ensembl chr 8:29,831,812...29,863,359 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 1:95,902,014...95,915,364
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G Tfpt TCF3 fusion partner involved_in IEA
ISO		 GO_REF:0000107
(MGI:5638510|PMID:23979016)		 Ensembl
RGD		 PMID:23979016 GO_REF:0000107 MGI:5638510 NCBI chr 1:65,587,855...65,597,407
Ensembl chr 1:65,582,359...65,611,689 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Yy1 YY1 transcription factor involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 6:127,706,739...127,731,907
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IEA		 (PMID:17237768)
GO_REF:0000107		 RGD
Ensembl		 PMID:17237768 GO_REF:0000107 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) RGD PMID:26586427 MGI:5705431 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) RGD PMID:26586427 MGI:5705431 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Aurkb aurora kinase B involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 involved_in ISO
IEA		 (PMID:25467444)
GO_REF:0000107		 RGD
Ensembl		 PMID:25467444 GO_REF:0000107 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:173,765,792...173,790,353
Ensembl chr 2:173,765,698...173,790,757 		JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5428344|PMID:22723415)
GO_REF:0000107		 RGD
Ensembl		 PMID:22723415 GO_REF:0000107 MGI:5428344 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 acts_upstream_of_or_within ISO MGI:3849598 (MGI:3047190|PMID:15240872) RGD PMID:15240872 MGI:3047190
G Fbxo4 F-box protein 4 involved_in ISO (PMID:16275645) RGD PMID:16275645 NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792 		JBrowse link
G Hmbox1 homeobox containing 1 involved_in ISO (PMID:23685356) RGD PMID:23685356 NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO
IEA		 (PMID:23935072)
GO_REF:0000107		 RGD
Ensembl		 PMID:23935072 GO_REF:0000107 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk15 mitogen-activated protein kinase 15 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052 		JBrowse link
G Nek2 NIMA-related kinase 2 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051 		JBrowse link
G Nek7 NIMA-related kinase 7 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296 		JBrowse link
G Parn poly(A)-specific ribonuclease involved_in ISO (PMID:26482878), (PMID:26950371) RGD PMID:26482878 PMID:26950371 NCBI chr10:1,410,636...1,548,573
Ensembl chr10:1,410,642...1,548,560 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:12768206), (PMID:12781132), (PMID:17237768) RGD PMID:12768206 PMID:12781132 PMID:17237768 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Prkcq protein kinase C, theta involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Tcp1 t-complex 1 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839 		JBrowse link
G Terc telomerase RNA component acts_upstream_of_or_within ISO MGI:1857930 (MGI:3774867|PMID:17982445) RGD PMID:17982445 MGI:3774867 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tnks tankyrase involved_in ISO (PMID:11739745), (PMID:12782650), (PMID:18221737) RGD PMID:11739745 PMID:12782650 PMID:18221737 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:19188702) RGD PMID:19188702 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
positive regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:17694070), (PMID:26586427) RGD PMID:17694070 PMID:26586427 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:21149580) RGD PMID:21149580 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 involved_in IDA PMID:23184978 BHF-UCL PMID:23184978 RGD:11567256 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein involved_in ISO (PMID:27510903) RGD PMID:27510903 NCBI chr16:22,837,586...22,868,293
Ensembl chr16:22,837,588...22,868,293 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:23959892) RGD PMID:23959892 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
positive regulation of telomeric loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
protection from non-homologous end joining at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IEA		 (MGI:3829120|PMID:18185984)
GO_REF:0000107		 RGD
Ensembl		 PMID:18185984 GO_REF:0000107 MGI:3829120 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Dclre1b DNA cross-link repair 1B involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:4462732|PMID:20551906), (MGI:4830207|PMID:20619712)
GO_REF:0000024
(PMID:16730175), (PMID:20479256)		 Ensembl
RGD
UniProt		 PMID:16730175 PMID:20479256 PMID:20551906 PMID:20619712 GO_REF:0000024 GO_REF:0000107 MGI:4462732 MGI:4830207 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423 		JBrowse link
G Pot1b protection of telomeres 1B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 9:9,670,355...9,728,624
Ensembl chr 9:9,670,362...9,728,532 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 ComplexPortal:CPX-1993 (PMID:14690602), (PMID:17499040), (PMID:24095731)
MGI:3619525 (MGI:3615734|PMID:15968270)
(MGI:4830207|PMID:20619712), (MGI:5883205|PMID:24120135)
PMID:21873635		 RGD PMID:14690602 PMID:15968270 PMID:17499040 PMID:20619712 PMID:24095731 More... MGI:3615734 MGI:4830207 MGI:5883205, RGD:13792537 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Terf2ip TERF2 interacting protein NOT|involved_in ISS
ISO		 GO_REF:0000024
(MGI:4440768|PMID:20339076), (MGI:4839412|PMID:20622869)		 UniProt
RGD		 PMID:20339076 PMID:20622869 GO_REF:0000024 MGI:4440768 MGI:4839412 NCBI chr19:39,976,965...39,984,055
Ensembl chr19:39,976,906...39,984,064 		JBrowse link
regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac8 histone deacetylase 8 involved_in ISO
IEA		 (PMID:16809764)
GO_REF:0000107		 RGD
Ensembl		 PMID:16809764 GO_REF:0000107 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D involved_in ISO (MGI:5438900|PMID:22633954) RGD PMID:22633954 MGI:5438900 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Lmna lamin A/C involved_in ISO (PMID:25399868) RGD PMID:25399868 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO
ISS		 (PMID:17765874)
GO_REF:0000024		 RGD
UniProt		 PMID:17765874 GO_REF:0000024 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:16522649) RGD PMID:16522649 NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200 		JBrowse link
G Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase involved_in ISO (PMID:17916692) RGD PMID:17916692 NCBI chr 1:172,441,892...172,543,667
Ensembl chr 1:172,444,936...172,543,698 		JBrowse link
G Smg5 SMG5 nonsense mediated mRNA decay factor involved_in ISO (PMID:16809764) RGD PMID:16809764 NCBI chr 2:173,804,987...173,832,102
Ensembl chr 2:173,805,019...173,832,102 		JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor involved_in ISO (PMID:12699629), (PMID:17916692) RGD PMID:12699629 PMID:17916692 NCBI chr10:59,786,258...60,014,395
Ensembl chr10:59,786,258...60,014,395 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:22536324) RGD PMID:22536324 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Upf1 UPF1, RNA helicase and ATPase involved_in ISO (PMID:17916692) RGD PMID:17916692 NCBI chr16:19,076,594...19,097,365
Ensembl chr16:19,076,322...19,096,568 		JBrowse link
G Ylpm1 YLP motif containing 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3525956|PMID:15100092)		 RGD PMID:15100092 PMID:21873635 MGI:3525956, RGD:13792537 NCBI chr 6:104,642,615...104,718,508
Ensembl chr 6:104,642,615...104,718,508 		JBrowse link
regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO UniProtKB:Q9NUX5 (PMID:26586433) RGD PMID:26586433 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO
IBA		 UniProtKB:Q13315 (PMID:26586433)
PMID:21873635		 RGD PMID:26586433 PMID:21873635 RGD:13792537 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Pot1b protection of telomeres 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:9,670,355...9,728,624
Ensembl chr 9:9,670,362...9,728,532 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA		 (PMID:19864690), (PMID:23685356)
PMID:21873635		 RGD PMID:19864690 PMID:23685356 PMID:21873635 RGD:13792537 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tinf2 TERF1 interacting nuclear factor 2 involved_in IBA
ISO		 PMID:21873635
(PMID:18669893)		 RGD PMID:18669893 PMID:21873635 RGD:13792537 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984 		JBrowse link
t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Nbn nibrin involved_in ISO
IEA		 (PMID:27918544)
GO_REF:0000107		 RGD
Ensembl		 PMID:27918544 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:24012755)
(MGI:5645200|PMID:22579284)		 RGD PMID:22579284 PMID:24012755 MGI:5645200 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:24012755)
(MGI:5645200|PMID:22579284)		 RGD PMID:22579284 PMID:24012755 MGI:5645200 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO
IBA		 (PMID:21903669)
PMID:21873635		 RGD PMID:21903669 PMID:21873635 RGD:13792537 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IBA		 (MGI:4441256|PMID:17632522)
PMID:21873635
UniProtKB:Q9NUX5 (PMID:17632522), (PMID:21852327), (PMID:25172512)		 RGD PMID:17632522 PMID:21852327 PMID:25172512 PMID:21873635 MGI:4441256, RGD:13792537 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Dclre1b DNA cross-link repair 1B involved_in ISO (PMID:20479256) RGD PMID:20479256 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 involved_in IDA PMID:15659580 UniProt PMID:15659580 RGD:10680046 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Pot1 protection of telomeres 1 involved_in IBA
ISO		 PMID:21873635
UniProtKB:Q96AP0 (PMID:15657433), (PMID:17632522), (PMID:21852327)		 RGD PMID:15657433 PMID:17632522 PMID:21852327 PMID:21873635 RGD:13792537 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Pot1b protection of telomeres 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:9,670,355...9,728,624
Ensembl chr 9:9,670,362...9,728,532 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:18710952) RGD PMID:18710952 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Spdya speedy/RINGO cell cycle regulator family member A acts_upstream_of_or_within ISO MGI:5888863 (MGI:5829137|PMID:28031483) RGD PMID:28031483 MGI:5829137 NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531 		JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO (PMID:21852327) RGD PMID:21852327 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:12768206), (PMID:14690602), (PMID:15657433), (PMID:21852327) RGD PMID:12768206 PMID:14690602 PMID:15657433 PMID:21852327 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 involved_in IBA
ISO		 PMID:21873635
(PMID:15133513), (PMID:18443218), (PMID:21852327)		 RGD PMID:15133513 PMID:18443218 PMID:21852327 PMID:21873635 RGD:13792537 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984 		JBrowse link
telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:15583028) RGD PMID:15583028 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
telomere maintenance via base-excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 involved_in ISO
IEA		 (PMID:24703901)
GO_REF:0000107		 RGD
Ensembl		 PMID:24703901 GO_REF:0000107 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
telomere maintenance via recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q13207 (MGI:5707585|PMID:21076401)		 Ensembl
RGD		 PMID:21076401 GO_REF:0000107 MGI:5707585 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO
IEA
ISS		 (PMID:17589526)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17589526 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rad51 RAD51 recombinase involved_in ISO UniProtKB:P02340 (MGI:5707585|PMID:21076401) RGD PMID:21076401 MGI:5707585 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rad51c RAD51 paralog C involved_in ISO UniProtKB:P02340 (MGI:5707585|PMID:21076401) RGD PMID:21076401 MGI:5707585 NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248 		JBrowse link
G Rad51d RAD51 paralog D involved_in ISO (PMID:15109494) RGD PMID:15109494 NCBI chr10:67,805,720...67,824,452
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Smc5 structural maintenance of chromosomes 5 involved_in ISO (PMID:17589526) RGD PMID:17589526 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096 		JBrowse link
G Smc6 structural maintenance of chromosomes 6 involved_in ISO (PMID:17589526) RGD PMID:17589526 NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746 		JBrowse link
G Tep1 telomerase associated protein 1 involved_in IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(PMID:10810353)		 Ensembl
RGD		 PMID:10810353 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr15:24,045,876...24,093,526
Ensembl chr15:24,045,878...24,093,526 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in IBA
ISO		 PMID:21873635
(PMID:15507207)		 RGD PMID:15507207 PMID:21873635 RGD:13792537 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Upf1 UPF1, RNA helicase and ATPase involved_in ISO (PMID:21829167) RGD PMID:21829167 NCBI chr16:19,076,594...19,097,365
Ensembl chr16:19,076,322...19,096,568 		JBrowse link
telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 involved_in ISO
ISS		 GO:0090669 (PMID:23685356), (PMID:26950371), (PMID:29695869)
GO_REF:0000024		 RGD
UniProt		 PMID:23685356 PMID:26950371 PMID:29695869 GO_REF:0000024
G Gar1 GAR1 ribonucleoprotein involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29695869)		 UniProt
Ensembl
RGD		 PMID:29695869 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:218,375,231...218,382,509
Ensembl chr 2:218,375,353...218,382,524 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO (PMID:10197982) RGD PMID:10197982 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO
IEA		 (PMID:10197982)
GO_REF:0000107		 RGD
Ensembl		 PMID:10197982 GO_REF:0000107 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Nhp2 NHP2 ribonucleoprotein involved_in ISO (PMID:29695869) RGD PMID:29695869 NCBI chr10:35,877,015...35,880,409
Ensembl chr10:35,877,054...35,882,545 		JBrowse link
G Nop10 NOP10 ribonucleoprotein involved_in ISO (PMID:29695869) RGD PMID:29695869 NCBI chr 3:99,066,857...99,067,942
Ensembl chr 3:99,066,857...99,067,942 		JBrowse link
G Parp4 poly (ADP-ribose) polymerase family, member 4 NOT|acts_upstream_of_or_within ISO MGI:109573 (MGI:3045914|PMID:15169895) RGD PMID:15169895 MGI:3045914 NCBI chr15:30,690,503...30,792,868
Ensembl chr15:30,686,613...30,828,810 		JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11701125)
GO_REF:0000107		 RGD
Ensembl		 PMID:11701125 GO_REF:0000107 NCBI chr15:38,098,027...38,157,143
Ensembl chr15:38,097,886...38,157,140 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:12768206) RGD PMID:12768206 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Ptges3 prostaglandin E synthase 3 involved_in ISO
IEA
IBA		 (PMID:10197982), (PMID:19740745)
GO_REF:0000107
(MGI:5819359|PMID:10197982)
PMID:21873635		 RGD
Ensembl		 PMID:10197982 PMID:19740745 PMID:21873635 GO_REF:0000107 MGI:5819359, RGD:13792537 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Ptges3l1 prostaglandin E synthase 3-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:42,215,200...42,224,472
Ensembl chr  X:42,214,756...42,225,047 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in IBA
IEA
ISS
ISO		 PMID:21873635
GO_REF:0000107
GO_REF:0000024
(PMID:9705271)		 Ensembl
UniProt
RGD		 PMID:9705271 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rpa1 replication protein A1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949 		JBrowse link
G Telo2 telomere maintenance 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:14,120,491...14,135,729
Ensembl chr10:14,120,818...14,135,698 		JBrowse link
G Tep1 telomerase associated protein 1 NOT|acts_upstream_of_or_within ISO MGI:2685589 (MGI:3045914|PMID:15169895) RGD PMID:15169895 MGI:3045914 NCBI chr15:24,045,876...24,093,526
Ensembl chr15:24,045,878...24,093,526 		JBrowse link
G Terc telomerase RNA component acts_upstream_of
involved_in		 TAS
ISO		 MGI:1857930 (MGI:3774867|PMID:17982445)
(PMID:17940095), (PMID:19701182), (PMID:9443919)		 RGD PMID:9443919 PMID:17940095 PMID:17982445 PMID:19701182 PMID:10423530 MGI:3774867, RGD:1299555 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA		 (PMID:9034193)
PMID:21873635
(PMID:23685356)		 RGD PMID:9034193 PMID:23685356 PMID:21873635 RGD:13792537 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO
IBA
ISS		 (PMID:16043710), (PMID:17940095), (PMID:19701182), (PMID:21531765), (PMID:29695869), (PMID:9443919), (PMID:9454332)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:9443919 PMID:9454332 PMID:16043710 PMID:17940095 PMID:19701182 More... GO_REF:0000024, RGD:13792537 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23685356), (PMID:29695869), (PMID:29804836)		 UniProt
RGD		 PMID:23685356 PMID:29695869 PMID:29804836 GO_REF:0000024 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctc1 CST telomere replication complex component 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:5427642 (MGI:5426340|PMID:22531781)		 RGD PMID:22531781 PMID:21873635 MGI:5426340, RGD:13792537 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298 		JBrowse link
G Dclre1b DNA cross-link repair 1B involved_in IEA
ISO		 GO_REF:0000107
(PMID:20479256)		 Ensembl
RGD		 PMID:20479256 GO_REF:0000107 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423 		JBrowse link
G Rad51 RAD51 recombinase involved_in ISO UniProtKB:P02340 (MGI:5707585|PMID:21076401) RGD PMID:21076401 MGI:5707585 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in IEA
IBA
ISS
ISO		 GO_REF:0000104
PMID:21873635
GO_REF:0000024
(PMID:19648609)		 UniProt
RGD		 PMID:19648609 PMID:21873635 GO_REF:0000024 GO_REF:0000104, RGD:13792537 NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531 		JBrowse link
G Terf2ip TERF2 interacting protein involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000104
(MGI:4440768|PMID:20339076), (MGI:4839412|PMID:20622869)
PMID:21873635		 UniProt
RGD		 PMID:20339076 PMID:20622869 PMID:21873635 GO_REF:0000024 GO_REF:0000104 MGI:4440768 MGI:4839412, RGD:13792537 NCBI chr19:39,976,965...39,984,055
Ensembl chr19:39,976,906...39,984,064 		JBrowse link
G Zbtb48 zinc finger and BTB domain containing 48 involved_in ISO (PMID:28082411), (PMID:28500257) RGD PMID:28082411 PMID:28500257 NCBI chr 5:162,525,234...162,533,604
Ensembl chr 5:162,525,235...162,533,585 		JBrowse link
telomere maintenance via telomere trimming term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nbn nibrin involved_in ISO UniProtKB:O43542 (PMID:27918544) RGD PMID:27918544 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO UniProtKB:O60934 (PMID:27918544) RGD PMID:27918544 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
telomeric 3' overhang formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dclre1b DNA cross-link repair 1B involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:4462732|PMID:20551906), (MGI:4830207|PMID:20619712)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:20551906 PMID:20619712 GO_REF:0000024 GO_REF:0000107 MGI:4462732 MGI:4830207 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in ISO
IEA		 (PMID:16374507)
GO_REF:0000107		 RGD
Ensembl		 PMID:16374507 GO_REF:0000107 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Nbn nibrin involved_in ISO
IEA		 (PMID:16374507)
GO_REF:0000107		 RGD
Ensembl		 PMID:16374507 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO
IEA		 (PMID:16374507)
GO_REF:0000107		 RGD
Ensembl		 PMID:16374507 GO_REF:0000107 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
telomeric D-loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase involved_in ISO (PMID:19734539) RGD PMID:19734539 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO UniProtKB:O94761 (PMID:22039056) RGD PMID:22039056 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Recql4 RecQ like helicase 4 involved_in ISO UniProtKB:P54274|UniProtKB:Q14191|UniProtKB:Q15554|UniProtKB:Q9NUX5 (PMID:22039056) RGD PMID:22039056 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO UniProtKB:O94761 (PMID:22039056) RGD PMID:22039056 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA		 UniProtKB:O94761 (PMID:22039056)
PMID:21873635		 RGD PMID:22039056 PMID:21873635 RGD:13792537 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Wrn WRN RecQ like helicase involved_in ISO UniProtKB:O94761 (PMID:15200954), (PMID:19734539), (PMID:22039056), (PMID:26420422) RGD PMID:15200954 PMID:19734539 PMID:22039056 PMID:26420422 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450 		JBrowse link
telomeric DNA-containing double minutes formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO (MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:3758502 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in ISO (MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:3758502 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
telomeric loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IBA		 (PMID:25620558)
(MGI:5522574|PMID:24115439), (MGI:5645200|PMID:22579284)
PMID:21873635		 RGD PMID:22579284 PMID:24115439 PMID:25620558 PMID:21873635 MGI:5522574 MGI:5645200, RGD:13792537 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
telomeric loop formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dclre1b DNA cross-link repair 1B involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:4830207|PMID:20619712)		 Ensembl
UniProt
RGD		 PMID:20619712 GO_REF:0000024 GO_REF:0000107 MGI:4830207 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423 		JBrowse link
G Pot1 protection of telomeres 1 NOT|involved_in ISO UniProtKB:H7BX60 (MGI:5883205|PMID:24120135) RGD PMID:24120135 MGI:5883205 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Terf1 telomeric repeat binding factor 1 NOT|involved_in ISO (MGI:5883205|PMID:24120135) RGD PMID:24120135 MGI:5883205 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in IBA
ISO		 PMID:21873635
(MGI:5883205|PMID:24120135)
(PMID:10338214)		 RGD PMID:10338214 PMID:24120135 PMID:21873635 MGI:5883205, RGD:13792537 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Terf2ip TERF2 interacting protein NOT|involved_in ISO (MGI:5883205|PMID:24120135) RGD PMID:24120135 MGI:5883205 NCBI chr19:39,976,965...39,984,055
Ensembl chr19:39,976,906...39,984,064 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      primary metabolic process 8928
        nucleobase-containing compound metabolic process 2826
          nucleic acid metabolic process 2315
            DNA metabolic process 1001
              telomere maintenance 140
                negative regulation of telomere maintenance + 35
                positive regulation of telomere maintenance + 67
                regulation of telomere maintenance + 95
                telomere capping + 38
                telomere maintenance in response to DNA damage + 27
                telomere maintenance via recombination + 15
                telomere maintenance via semi-conservative replication + 3
                telomere maintenance via telomere lengthening + 79
                telomere maintenance via telomere trimming + 8
                telomeric loop disassembly + 9
                telomeric loop formation + 5
Path 2
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      cellular metabolic process 7496
        cellular aromatic compound metabolic process 3078
          nucleobase-containing compound metabolic process 2826
            nucleic acid metabolic process 2315
              DNA metabolic process 1001
                telomere maintenance 140
                  negative regulation of telomere maintenance + 35
                  positive regulation of telomere maintenance + 67
                  regulation of telomere maintenance + 95
                  telomere capping + 38
                  telomere maintenance in response to DNA damage + 27
                  telomere maintenance via recombination + 15
                  telomere maintenance via semi-conservative replication + 3
                  telomere maintenance via telomere lengthening + 79
                  telomere maintenance via telomere trimming + 8
                  telomeric loop disassembly + 9
                  telomeric loop formation + 5
paths to the root