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ONTOLOGY REPORT - ANNOTATIONS

Term:telomere maintenance
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Accession:GO:0000723 term browser browse the term
Definition:Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
Synonyms:related_synonym: regulation of telomere length
 xref: Reactome:R-HSA-157579 "Telomere Maintenance"


show annotations for term's descendants           Sort by:
telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:15181449)
GO_REF:0000002
GO_REF:0000107 		RGD
InterPro
Ensembl		 PMID:15181449 GO_REF:0000002 GO_REF:0000107 NCBI chr19:50,496,634...50,499,397
Ensembl chr19:50,496,635...50,499,326 		JBrowse link
G Actl6a actin-like 6A involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 2:117,413,206...117,436,758
Ensembl chr 2:117,418,601...117,436,754 		JBrowse link
G Actr5 actin related protein 5 involved_in ISO (PMID:23979016) RGD PMID:23979016 NCBI chr 3:167,702,299...167,715,736
Ensembl chr 3:167,702,482...167,715,730 		JBrowse link
G Actr8 actin related protein 8 involved_in ISO (PMID:23979016) RGD PMID:23979016 NCBI chr16:5,170,649...5,192,883
Ensembl chr16:5,167,237...5,186,180 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 involved_in ISO
IEA 		(PMID:24703901)
GO_REF:0000107 		RGD
Ensembl		 PMID:24703901 GO_REF:0000107 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329 		JBrowse link
G Atm ATM serine/threonine kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Atr ATR serine/threonine kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718 		JBrowse link
G Blm BLM RecQ like helicase involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000117
GO_REF:0000107
(PMID:11735402)
MGI:109558|MGI:109635 (PMID:15367665) 		GO_Central
UniProt
Ensembl
RGD		 PMID:11735402 PMID:15367665 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:143,819,072...143,905,300
Ensembl chr 1:143,819,090...143,905,210 		JBrowse link
G Ccne1 cyclin E1 acts_upstream_of_or_within ISO
IEA 		MGI:1329034 (PMID:24586195)
GO_REF:0000107 		RGD
Ensembl		 PMID:24586195 GO_REF:0000107 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822 		JBrowse link
G Ccne2 cyclin E2 acts_upstream_of_or_within ISO
IEA 		MGI:88316 (PMID:24586195)
GO_REF:0000107 		RGD
Ensembl		 PMID:24586195 GO_REF:0000107 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882 		JBrowse link
G Cdk2 cyclin dependent kinase 2 acts_upstream_of_or_within ISO (PMID:28216226) RGD PMID:28216226 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in ISO
IEA 		(PMID:19854131)
GO_REF:0000107 		RGD
Ensembl		 PMID:19854131 GO_REF:0000107 NCBI chr10:54,212,537...54,234,146
Ensembl chr10:54,207,083...54,234,147 		JBrowse link
G Dclre1b DNA cross-link repair 1B involved_in ISO
IEA
IBA
ISS 		(PMID:20655466)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024 		RGD
Ensembl
GO_Central
UniProt		 PMID:20655466 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:193,998,350...194,006,873
Ensembl chr 2:193,998,354...194,006,864 		JBrowse link
G Dclre1c DNA cross-link repair 1C involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:12615897) 		GO_Central
RGD		 PMID:12615897 GO_REF:0000033 NCBI chr17:79,684,988...79,718,399
Ensembl chr17:79,678,698...79,718,734 		JBrowse link
G Dna2 DNA replication helicase/nuclease 2 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,660,339...25,689,285 JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 NOT|involved_in ISO (PMID:24813886) RGD PMID:24813886 NCBI chr10:80,083,585...80,092,450
Ensembl chr10:80,083,585...80,092,301 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:24813886) 		Ensembl
RGD		 PMID:24813886 GO_REF:0000107 NCBI chr10:14,413,661...14,420,489
Ensembl chr10:14,417,735...14,420,489 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO UniProtKB:Q15554 (PMID:14690602), (PMID:17055345) RGD PMID:14690602 PMID:17055345 NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539 		JBrowse link
G Fbxo4 F-box protein 4 involved_in ISO (PMID:16275645) RGD PMID:16275645 NCBI chr 2:54,902,394...54,915,388
Ensembl chr 2:54,902,394...54,915,388 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A acts_upstream_of_or_within ISO MGI:3028843 (PMID:14701760) RGD PMID:14701760 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:87,902,458...87,917,221
Ensembl chr14:87,902,458...87,917,134 		JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 3:126,822,280...126,919,532
Ensembl chr 3:126,822,280...126,919,532 		JBrowse link
G Ino80b INO80 complex subunit B involved_in ISO (PMID:23979016) RGD PMID:23979016 NCBI chr 4:117,185,427...117,188,930
Ensembl chr 4:117,185,620...117,189,168 		JBrowse link
G Ino80c INO80 complex subunit C involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr18:15,653,508...15,752,455
Ensembl chr18:15,653,511...15,668,144 		JBrowse link
G Ino80d INO80 complex subunit D involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 9:71,940,941...72,007,879
Ensembl chr 9:71,951,031...72,040,232 		JBrowse link
G Lrrc34 leucine rich repeat containing 34 acts_upstream_of_or_within ISO
IEA 		MGI:101893 (PMID:34549596)
GO_REF:0000107 		RGD
Ensembl		 PMID:34549596 GO_REF:0000107 NCBI chr 2:114,680,787...114,702,961
Ensembl chr 2:114,680,094...114,702,961 		JBrowse link
G Lto1 LTO1 maturation factor of ABCE1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:209,502,900...209,510,237
Ensembl chr 1:209,498,312...209,517,347 		JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 7:132,262,719...132,271,533
Ensembl chr 7:132,262,722...132,271,533 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:19,913,772...19,961,904 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit involved_in ISO (PMID:24813886) RGD PMID:24813886 NCBI chr 1:212,219,793...212,225,214
Ensembl chr 1:212,219,795...212,225,068 		JBrowse link
G Nbn nibrin involved_in
acts_upstream_of_or_within 		ISO
IEA
ISS 		(PMID:11448772)
(PMID:28216226)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000024 		RGD
Ensembl
InterPro
UniProt		 PMID:11448772 PMID:28216226 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162 		JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 8:38,089,574...38,121,506
Ensembl chr 8:38,089,999...38,121,501 		JBrowse link
G Nhej1 nonhomologous end-joining factor 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28369633)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28369633 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:83,974,995...84,071,161
Ensembl chr 9:83,974,997...84,070,594 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 acts_upstream_of_or_within ISO MGI:1857862 (PMID:12707040) RGD PMID:12707040 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Parp3 poly (ADP-ribose) polymerase family, member 3 acts_upstream_of_or_within ISO
IEA 		(PMID:21270334)
GO_REF:0000107 		RGD
Ensembl		 PMID:21270334 GO_REF:0000107 NCBI chr 8:115,989,721...115,995,822
Ensembl chr 8:115,987,176...115,995,472 		JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:75,005,820...75,015,331
Ensembl chr 8:75,006,815...75,015,331 		JBrowse link
G Pot1 protection of telomeres 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
G Pot1b protection of telomeres 1B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:9,997,508...10,055,752
Ensembl chr 9:9,997,195...10,055,755 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO
IEA 		MGI:1919077 (PMID:34549596)
GO_REF:0000107 		RGD
Ensembl		 PMID:34549596 GO_REF:0000107 NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha acts_upstream_of_or_within ISO (PMID:28216226) RGD PMID:28216226 NCBI chr 1:210,914,576...210,918,193
Ensembl chr 1:210,914,567...210,918,193 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000117
GO_REF:0000107
MGI:1857113 (PMID:15010310) 		GO_Central
UniProt
Ensembl
RGD		 PMID:15010310 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:98,544,954...98,762,108 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in TAS
IEA 		GO_REF:0000002 InterPro
RGD		 PMID:10908350 GO_REF:0000002, RGD:68816 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Rad51d RAD51 paralog D involved_in ISO
IEA 		(PMID:15109494)
GO_REF:0000117
UniProtKB:P02340 (PMID:15109494) 		RGD
UniProt		 PMID:15109494 GO_REF:0000117 NCBI chr10:68,303,350...68,322,002
Ensembl chr10:68,238,273...68,321,902 		JBrowse link
G Recql4 RecQ like helicase 4 involved_in ISO
IBA 		(PMID:22039056)
GO_REF:0000033 		RGD
GO_Central		 PMID:22039056 GO_REF:0000033 NCBI chr 7:110,304,092...110,311,426
Ensembl chr 7:110,304,094...110,311,258 		JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase involved_in IEA
ISO
IBA 		UniProtKB:P02340 (PMID:15109494) Ensembl
RGD
GO_Central		 PMID:15109494 GO_REF:0000033 GO_REF:0000107
G Rif1 replication timing regulatory factor 1 involved_in IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000117
GO_REF:0000107
(PMID:24735877) 		GO_Central
UniProt
Ensembl
RGD		 PMID:24735877 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 3:56,963,840...57,017,106
Ensembl chr 3:56,963,854...57,017,106 		JBrowse link
G Rpa1 replication protein A1 involved_in ISO
IEA 		(PMID:17959650)
GO_REF:0000107 		RGD
Ensembl		 PMID:17959650 GO_REF:0000107 NCBI chr10:60,647,185...60,698,279
Ensembl chr10:60,647,185...60,698,279 		JBrowse link
G Rpa2 replication protein A2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:17959650) 		UniProt
RGD		 PMID:17959650 GO_REF:0000024 NCBI chr 5:150,260,668...150,271,329
Ensembl chr 5:150,260,723...150,271,546 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in
acts_upstream_of_or_within 		ISO
IEA
ISS 		(PMID:23453664)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000104
MGI:3052235 (PMID:15210109)
GO_REF:0000024 		RGD
Ensembl
InterPro
UniProt		 PMID:15210109 PMID:23453664 GO_REF:0000002 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 involved_in ISO (PMID:23979016) RGD PMID:23979016 NCBI chr 4:122,489,754...122,524,666
Ensembl chr 4:122,489,680...122,524,665 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:105,038,174...105,051,720 		JBrowse link
G Slc25a16 solute carrier family 25 member 16 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,659,847...25,717,080
Ensembl chr20:25,660,339...25,689,285
Ensembl chr20:25,660,339...25,689,285 		JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:15767676) RGD PMID:15767676 NCBI chr 9:93,758,975...93,825,068
Ensembl chr 9:93,759,075...93,825,068 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISS
ISO 		GO_REF:0000024
(PMID:19854130) 		UniProt
RGD		 PMID:19854130 GO_REF:0000024 NCBI chr 1:256,336,916...256,371,143
Ensembl chr 1:256,315,367...256,370,736 		JBrowse link
G Terc telomerase RNA component acts_upstream_of_or_within ISO MGI:109635|MGI:1328362|MGI:1857930 (PMID:15235603), (PMID:15367665), (PMID:17145779) RGD PMID:15235603 PMID:15367665 PMID:17145779 NCBI chr 2:114,744,148...114,744,535 JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IEA 		(PMID:24415760)
GO_REF:0000002
GO_REF:0000104
GO_REF:0000107 		RGD
InterPro
UniProt
Ensembl		 PMID:24415760 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:8,226,345...8,255,753 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in
acts_upstream_of
acts_upstream_of_or_within 		ISO
IEA 		(PMID:20655466), (PMID:28216226)
GO_REF:0000002
GO_REF:0000104
GO_REF:0000107
MGI:3619525 (PMID:15968270)
(PMID:15010310) 		RGD
InterPro
UniProt
Ensembl		 PMID:15010310 PMID:15968270 PMID:20655466 PMID:28216226 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Terf2ip TERF2 interacting protein involved_in IEA GO_REF:0000002
GO_REF:0000107 		InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr19:56,886,211...56,893,300
Ensembl chr19:56,886,153...56,893,392 		JBrowse link
G Tert telomerase reverse transcriptase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Tfpt TCF3 fusion partner involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 1:74,502,994...74,512,766
Ensembl chr 1:74,502,994...74,513,370 		JBrowse link
G Tnks2 tankyrase 2 NOT|acts_upstream_of_or_within ISO MGI:3621819|MGI:3621924 (PMID:16507984), (PMID:16507985) RGD PMID:16507984 PMID:16507985 NCBI chr 1:243,980,432...244,033,629
Ensembl chr 1:243,980,414...244,033,634 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:23979016) RGD PMID:23979016 NCBI chr13:58,070,947...58,106,825
Ensembl chr13:58,042,029...58,107,441 		JBrowse link
G Wrn WRN RecQ like helicase involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000117
(PMID:11735402), (PMID:18212065)
MGI:109558|MGI:1328362|MGI:2156622 (PMID:12707040), (PMID:15235603), (PMID:15367665) 		GO_Central
UniProt
RGD		 PMID:11735402 PMID:12707040 PMID:15235603 PMID:15367665 PMID:18212065 GO_REF:0000033 GO_REF:0000117 NCBI chr16:65,466,552...65,602,951
Ensembl chr16:65,456,254...65,602,951 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 9:81,404,507...81,493,293
Ensembl chr 9:81,375,863...81,493,293 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 7:115,423,026...115,443,884
Ensembl chr 7:115,422,662...115,443,884 		JBrowse link
G Yy1 YY1 transcription factor involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 6:133,471,615...133,500,875
Ensembl chr 6:133,471,562...133,497,257 		JBrowse link
G Zfp365 zinc finger protein 365 involved_in ISS
ISO
IBA
IEA 		GO_REF:0000024
(PMID:23776040)
GO_REF:0000033
GO_REF:0000107 		UniProt
RGD
GO_Central
Ensembl		 PMID:23776040 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:20,665,122...20,688,607
Ensembl chr20:20,665,046...20,690,114 		JBrowse link
G Zfp827 zinc finger protein 827 involved_in ISO
IEA 		(PMID:25150861)
GO_REF:0000107 		RGD
Ensembl		 PMID:25150861 GO_REF:0000107 NCBI chr19:45,624,849...45,791,739
Ensembl chr19:45,614,604...45,844,430 		JBrowse link
mitotic telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dna2 DNA replication helicase/nuclease 2 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,660,339...25,689,285 JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO
IEA 		UniProtKB:Q0VGM9 (PMID:24115439)
GO_REF:0000107 		RGD
Ensembl		 PMID:24115439 GO_REF:0000107 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IEA 		(PMID:24115439)
GO_REF:0000107 		RGD
Ensembl		 PMID:24115439 GO_REF:0000107 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
G Slc25a16 solute carrier family 25 member 16 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,659,847...25,717,080
Ensembl chr20:25,660,339...25,689,285
Ensembl chr20:25,660,339...25,689,285 		JBrowse link
negative regulation of protection from non-homologous end joining at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO
IEA 		(PMID:14690602)
GO_REF:0000107 		RGD
Ensembl		 PMID:14690602 GO_REF:0000107 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 2:22,686,506...22,932,929
Ensembl chr 2:22,686,508...22,933,160 		JBrowse link
negative regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IEA
IBA 		(PMID:25620558)
GO_REF:0000117
GO_REF:0000107
(PMID:22579284), (PMID:24115439)
GO_REF:0000033 		RGD
UniProt
Ensembl
GO_Central		 PMID:22579284 PMID:24115439 PMID:25620558 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IEA 		(PMID:15507207)
GO_REF:0000107 		RGD
Ensembl		 PMID:15507207 GO_REF:0000107 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:19581589) RGD PMID:19581589 NCBI chr 9:81,404,507...81,493,293
Ensembl chr 9:81,375,863...81,493,293 		JBrowse link
negative regulation of telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:17694070) RGD PMID:17694070 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Nbn nibrin involved_in IEA
ISO 		GO_REF:0000107
(PMID:17694070) 		Ensembl
RGD		 PMID:17694070 GO_REF:0000107 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO
IEA 		(PMID:17694070)
GO_REF:0000107 		RGD
Ensembl		 PMID:17694070 GO_REF:0000107 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor involved_in ISO
IEA 		(PMID:12676087)
GO_REF:0000107 		RGD
Ensembl		 PMID:12676087 GO_REF:0000107 NCBI chr10:60,284,628...60,512,738
Ensembl chr10:60,284,628...60,512,733 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IEA 		(PMID:24270157)
GO_REF:0000107 		RGD
Ensembl		 PMID:24270157 GO_REF:0000107 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
negative regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IEA 		(PMID:11971978)
GO_REF:0000107 		RGD
Ensembl		 PMID:11971978 GO_REF:0000107 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Terf2ip TERF2 interacting protein involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:56,886,211...56,893,300
Ensembl chr19:56,886,153...56,893,392 		JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 acts_upstream_of_or_within ISO (PMID:12676566) RGD PMID:12676566 NCBI chr15:33,140,611...33,146,930
Ensembl chr15:33,140,714...33,146,930 		JBrowse link
negative regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IEA 		(PMID:22579284)
GO_REF:0000107 		RGD
Ensembl		 PMID:22579284 GO_REF:0000107 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IEA
IBA 		(PMID:15507207)
GO_REF:0000117
GO_REF:0000107
(PMID:24120135)
GO_REF:0000033 		RGD
UniProt
Ensembl
GO_Central		 PMID:15507207 PMID:24120135 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in IEA
ISO
IBA 		GO_REF:0000107
UniProtKB:Q9NUX5 (PMID:15181449), (PMID:15380063), (PMID:25172512)
GO_REF:0000033 		Ensembl
RGD
GO_Central		 PMID:15181449 PMID:15380063 PMID:25172512 GO_REF:0000033 GO_REF:0000107 NCBI chr19:50,496,634...50,499,397
Ensembl chr19:50,496,635...50,499,326 		JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in ISO
IEA 		(PMID:22763445)
GO_REF:0000107 		RGD
Ensembl		 PMID:22763445 GO_REF:0000107 NCBI chr10:54,212,537...54,234,146
Ensembl chr10:54,207,083...54,234,147 		JBrowse link
G Dcp2 decapping mRNA 2 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr18:37,001,615...37,037,949
Ensembl chr18:37,001,615...37,049,939 		JBrowse link
G Exosc10 exosome component 10 involved_in ISO
IEA 		(PMID:26950371)
GO_REF:0000107 		RGD
Ensembl		 PMID:26950371 GO_REF:0000107 NCBI chr 5:164,278,414...164,302,067
Ensembl chr 5:164,278,440...164,302,067 		JBrowse link
G Gnl3l G protein nucleolar 3 like involved_in ISO
IEA 		(PMID:18082603)
GO_REF:0000107 		RGD
Ensembl		 PMID:18082603 GO_REF:0000107 NCBI chr  X:23,404,324...23,437,501
Ensembl chr  X:23,404,324...23,439,315 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) RGD PMID:23935072 NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:136,253,278...136,260,085 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr15:27,253,098...27,282,779
Ensembl chr15:27,253,098...27,282,715 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
ISO 		GO_REF:0000107
(PMID:18082603) 		Ensembl
RGD		 PMID:18082603 GO_REF:0000107 NCBI chr13:92,609,791...92,618,580
Ensembl chr13:92,605,216...92,618,612 		JBrowse link
G Nat10 N-acetyltransferase 10 involved_in ISO
IEA 		(PMID:18082603)
GO_REF:0000107 		RGD
Ensembl		 PMID:18082603 GO_REF:0000107 NCBI chr 3:110,566,582...110,604,829
Ensembl chr 3:110,566,582...110,604,836 		JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in ISO
IEA 		(PMID:16522649), (PMID:23657261)
GO_REF:0000107
GO_REF:0000104 		RGD
Ensembl
UniProt		 PMID:16522649 PMID:23657261 GO_REF:0000104 GO_REF:0000107 NCBI chr 8:75,005,820...75,015,331
Ensembl chr 8:75,006,815...75,015,331 		JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 involved_in ISO (PMID:11701125), (PMID:21119197) RGD PMID:11701125 PMID:21119197 NCBI chr15:42,273,805...42,333,047
Ensembl chr15:42,273,799...42,333,047 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:19567472) RGD PMID:19567472 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO UniProtKB:Q96AP0 (PMID:15181449), (PMID:15632080) RGD PMID:15181449 PMID:15632080 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISO (PMID:22763445) RGD PMID:22763445 NCBI chr 1:256,336,916...256,371,143
Ensembl chr 1:256,315,367...256,370,736 		JBrowse link
G Ten1 TEN1 subunit of CST complex involved_in ISO
IBA 		(PMID:22763445)
GO_REF:0000033 		RGD
GO_Central		 PMID:22763445 GO_REF:0000033 NCBI chr10:101,930,212...101,951,932
Ensembl chr10:101,930,222...101,953,979 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr19:34,984,244...35,042,423
Ensembl chr19:34,980,296...35,042,399 		JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IEA 		UniProtKB:O14746 (PMID:11971978)
GO_REF:0000107 		RGD
Ensembl		 PMID:11971978 GO_REF:0000107 NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:8,226,345...8,255,753 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IEA 		(PMID:17055345)
GO_REF:0000107 		RGD
Ensembl		 PMID:17055345 GO_REF:0000107 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 involved_in ISO (PMID:10581025), (PMID:15133513) RGD PMID:10581025 PMID:15133513 NCBI chr15:33,140,611...33,146,930
Ensembl chr15:33,140,714...33,146,930 		JBrowse link
G Tp53 tumor protein p53 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10597287) 		Ensembl
RGD		 PMID:10597287 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
negative regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:18812185) RGD PMID:18812185 NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539 		JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO (PMID:15044100) RGD PMID:15044100 NCBI chr 7:132,262,719...132,271,533
Ensembl chr 7:132,262,722...132,271,533 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO (PMID:26586427) RGD PMID:26586427 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr 1:190,716,759...190,722,307
Ensembl chr 1:190,714,490...190,722,307 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO
IEA 		(PMID:24012755)
GO_REF:0000107 		RGD
Ensembl		 PMID:24012755 GO_REF:0000107 NCBI chr10:12,032,131...12,055,685
Ensembl chr10:12,033,048...12,055,650 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IEA 		(PMID:24012755)
GO_REF:0000107 		RGD
Ensembl		 PMID:24012755 GO_REF:0000107 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Tnks tankyrase involved_in ISO (PMID:25939383) RGD PMID:25939383 NCBI chr16:63,922,969...64,073,972
Ensembl chr16:63,928,281...64,079,282 		JBrowse link
G Tnks2 tankyrase 2 involved_in ISO
IEA 		(PMID:25939383)
GO_REF:0000107 		RGD
Ensembl		 PMID:25939383 GO_REF:0000107 NCBI chr 1:243,980,432...244,033,629
Ensembl chr 1:243,980,414...244,033,634 		JBrowse link
negative regulation of telomeric D-loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IEA 		(PMID:15200954)
GO_REF:0000107 		RGD
Ensembl		 PMID:15200954 GO_REF:0000107 NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:8,226,345...8,255,753 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA
IEA 		(PMID:15200954)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:15200954 GO_REF:0000033 GO_REF:0000107 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
positive regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:22579284) RGD PMID:22579284 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:22579284) RGD PMID:22579284 NCBI chr 1:190,716,759...190,722,307
Ensembl chr 1:190,714,490...190,722,307 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:22579284) RGD PMID:22579284 NCBI chr10:12,032,131...12,055,685
Ensembl chr10:12,033,048...12,055,650 		JBrowse link
positive regulation of telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd66 ankyrin repeat domain 66 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:24,918,206...24,938,481
Ensembl chr 9:24,912,521...24,938,488 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D acts_upstream_of ISO
IEA 		(PMID:22633954)
GO_REF:0000107 		RGD
Ensembl		 PMID:22633954 GO_REF:0000107 NCBI chr14:9,918,630...9,938,072
Ensembl chr14:9,919,739...9,938,066 		JBrowse link
G Nabp2 nucleic acid binding protein 2 involved_in ISO
IEA 		(PMID:25589350)
GO_REF:0000107 		RGD
Ensembl		 PMID:25589350 GO_REF:0000107 NCBI chr 7:1,415,491...1,421,113
Ensembl chr 7:1,415,492...1,422,682 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IEA 		(PMID:23959892)
GO_REF:0000107 		RGD
Ensembl		 PMID:23959892 GO_REF:0000107 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
G Tnks tankyrase involved_in IBA
ISO 		GO_REF:0000033
(PMID:25939383) 		GO_Central
RGD		 PMID:25939383 GO_REF:0000033 NCBI chr16:63,922,969...64,073,972
Ensembl chr16:63,928,281...64,079,282 		JBrowse link
G Tnks2 tankyrase 2 involved_in IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:25939383) 		GO_Central
Ensembl
RGD		 PMID:25939383 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:243,980,432...244,033,629
Ensembl chr 1:243,980,414...244,033,634 		JBrowse link
positive regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:20110566)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:20110566 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:74,916,548...75,062,880
Ensembl chr  X:74,916,548...75,062,880 		JBrowse link
G Aurkb aurora kinase B acts_upstream_of_or_within ISO
IEA 		(PMID:21531765)
GO_REF:0000107 		RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO
IEA 		(PMID:22238380)
GO_REF:0000107 		RGD
Ensembl		 PMID:22238380 GO_REF:0000107 NCBI chr 2:149,006,089...149,044,192
Ensembl chr 2:149,006,089...149,044,191 		JBrowse link
G Gnl3 G protein nucleolar 3 involved_in ISO
IEA 		(PMID:22641345)
GO_REF:0000107 		RGD
Ensembl		 PMID:22641345 GO_REF:0000107 NCBI chr16:6,213,844...6,220,029
Ensembl chr16:6,213,871...6,219,845 		JBrowse link
G Klf4 KLF transcription factor 4 acts_upstream_of ISO
IEA 		(PMID:20629177)
GO_REF:0000107 		RGD
Ensembl		 PMID:20629177 GO_REF:0000107 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 acts_upstream_of_or_within ISO
IEA 		(PMID:21531765)
GO_REF:0000107 		RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:7,389,155...7,398,377 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 acts_upstream_of_or_within ISO
IEA 		(PMID:21531765)
GO_REF:0000107 		RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr 1:50,977,870...51,067,117
Ensembl chr 1:50,979,586...51,067,117 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 acts_upstream_of_or_within ISO
IEA 		(PMID:21531765)
GO_REF:0000107 		RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk15 mitogen-activated protein kinase 15 acts_upstream_of ISO
IEA 		(PMID:21531765)
GO_REF:0000107 		RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr 7:109,575,619...109,595,339
Ensembl chr 7:109,575,561...109,595,346 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 acts_upstream_of_or_within ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 acts_upstream_of ISO (PMID:21531765) RGD PMID:21531765 NCBI chr12:40,654,220...40,673,740
Ensembl chr12:40,654,423...40,677,170 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in ISO (PMID:16374507) RGD PMID:16374507 NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:19,913,772...19,961,904 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:9637678) RGD PMID:9637678 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Nbn nibrin involved_in IEA
ISO 		GO_REF:0000107
(PMID:16374507) 		Ensembl
RGD		 PMID:16374507 GO_REF:0000107 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162 		JBrowse link
G Nek2 NIMA-related kinase 2 acts_upstream_of_or_within ISO (PMID:21531765) RGD PMID:21531765 NCBI chr13:105,936,809...105,950,054
Ensembl chr13:105,936,788...105,950,056 		JBrowse link
G Nek7 NIMA-related kinase 7 acts_upstream_of_or_within ISO
IEA 		(PMID:21531765)
GO_REF:0000107 		RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr13:52,573,730...52,700,869
Ensembl chr13:52,573,730...52,700,823 		JBrowse link
G Nvl nuclear VCP-like acts_upstream_of ISO (PMID:22226966) RGD PMID:22226966 NCBI chr13:95,385,389...95,438,490
Ensembl chr13:95,372,641...95,442,291 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta acts_upstream_of ISO
IEA 		(PMID:21531765)
GO_REF:0000107 		RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr20:37,511,564...37,608,607
Ensembl chr20:37,512,822...37,608,401 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO
IEA 		(PMID:26119943)
GO_REF:0000107
(PMID:22641345) 		RGD
Ensembl		 PMID:22641345 PMID:26119943 GO_REF:0000107 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase acts_upstream_of_or_within ISO
IEA 		(PMID:21531765)
GO_REF:0000107 		RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr 1:104,476,801...104,483,409
Ensembl chr 1:104,478,088...104,483,408 		JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in ISO
IEA 		(PMID:23426265)
GO_REF:0000107 		RGD
Ensembl		 PMID:23426265 GO_REF:0000107 NCBI chr20:2,827,802...2,842,418
Ensembl chr20:2,827,802...2,842,418 		JBrowse link
G Prkcq protein kinase C, theta acts_upstream_of_or_within ISO
IEA 		(PMID:21531765)
GO_REF:0000107 		RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr17:72,156,215...72,288,508
Ensembl chr17:72,156,215...72,288,508 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO
IEA 		(PMID:16374507)
GO_REF:0000107 		RGD
Ensembl		 PMID:16374507 GO_REF:0000107 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IEA 		(PMID:22579284)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:22579284 GO_REF:0000107 GO_REF:0000117 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:23201774), (PMID:25819580) RGD PMID:23201774 PMID:25819580 NCBI chr 7:8,733,056...8,738,543
Ensembl chr 7:8,732,974...8,738,542 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO
IEA 		(PMID:24012755)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:24012755 GO_REF:0000107 GO_REF:0000117 NCBI chr10:12,032,131...12,055,685
Ensembl chr10:12,033,048...12,055,650 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:24012755)
GO_REF:0000117
GO_REF:0000107
MGI:3619525 (PMID:15968270) 		RGD
UniProt
Ensembl		 PMID:15968270 PMID:24012755 GO_REF:0000107 GO_REF:0000117 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
positive regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actl6a actin-like 6A involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 2:117,413,206...117,436,758
Ensembl chr 2:117,418,601...117,436,754 		JBrowse link
G Actr5 actin related protein 5 involved_in ISO (PMID:23979016) RGD PMID:23979016 NCBI chr 3:167,702,299...167,715,736
Ensembl chr 3:167,702,482...167,715,730 		JBrowse link
G Actr8 actin related protein 8 involved_in ISO (PMID:23979016) RGD PMID:23979016 NCBI chr16:5,170,649...5,192,883
Ensembl chr16:5,167,237...5,186,180 		JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 3:126,822,280...126,919,532
Ensembl chr 3:126,822,280...126,919,532 		JBrowse link
G Ino80b INO80 complex subunit B involved_in ISO (PMID:23979016) RGD PMID:23979016 NCBI chr 4:117,185,427...117,188,930
Ensembl chr 4:117,185,620...117,189,168 		JBrowse link
G Ino80c INO80 complex subunit C involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr18:15,653,508...15,752,455
Ensembl chr18:15,653,511...15,668,144 		JBrowse link
G Ino80d INO80 complex subunit D involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 9:71,940,941...72,007,879
Ensembl chr 9:71,951,031...72,040,232 		JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 7:132,262,719...132,271,533
Ensembl chr 7:132,262,722...132,271,533 		JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 8:38,089,574...38,121,506
Ensembl chr 8:38,089,999...38,121,501 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 involved_in ISO (PMID:23979016) RGD PMID:23979016 NCBI chr 4:122,489,754...122,524,666
Ensembl chr 4:122,489,680...122,524,665 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:105,038,174...105,051,720 		JBrowse link
G Tfpt TCF3 fusion partner involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 1:74,502,994...74,512,766
Ensembl chr 1:74,502,994...74,513,370 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:23979016) RGD PMID:23979016 NCBI chr13:58,070,947...58,106,825
Ensembl chr13:58,042,029...58,107,441 		JBrowse link
G Yy1 YY1 transcription factor involved_in ISO
IEA 		(PMID:23979016)
GO_REF:0000107 		RGD
Ensembl		 PMID:23979016 GO_REF:0000107 NCBI chr 6:133,471,615...133,500,875
Ensembl chr 6:133,471,562...133,497,257 		JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:26586427) RGD PMID:26586427 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (PMID:26586427) RGD PMID:26586427 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718 		JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 acts_upstream_of ISO
IEA 		(PMID:25467444)
GO_REF:0000107 		RGD
Ensembl		 PMID:25467444 GO_REF:0000107 NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 acts_upstream_of ISO
IEA 		(PMID:25467444)
GO_REF:0000107 		RGD
Ensembl		 PMID:25467444 GO_REF:0000107 NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925 		JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 acts_upstream_of ISO
IEA 		(PMID:25467444)
GO_REF:0000107 		RGD
Ensembl		 PMID:25467444 GO_REF:0000107 NCBI chr14:101,193,057...101,205,935
Ensembl chr14:101,192,772...101,205,770 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 acts_upstream_of ISO
IEA 		(PMID:25467444)
GO_REF:0000107 		RGD
Ensembl		 PMID:25467444 GO_REF:0000107 NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A acts_upstream_of ISO
IEA 		(PMID:25467444)
GO_REF:0000107 		RGD
Ensembl		 PMID:25467444 GO_REF:0000107 NCBI chr12:32,508,842...32,519,072
Ensembl chr12:32,508,675...32,519,119 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 acts_upstream_of ISO
IEA 		(PMID:25467444)
GO_REF:0000107 		RGD
Ensembl		 PMID:25467444 GO_REF:0000107 NCBI chr 4:119,546,730...119,563,973
Ensembl chr 4:119,546,730...119,563,973 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 acts_upstream_of ISO
IEA 		(PMID:25467444)
GO_REF:0000107 		RGD
Ensembl		 PMID:25467444 GO_REF:0000107 NCBI chr11:40,196,619...40,208,328
Ensembl chr11:40,196,619...40,208,328 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of ISO
IEA 		(PMID:22723415)
GO_REF:0000107 		RGD
Ensembl		 PMID:22723415 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 acts_upstream_of_or_within ISO MGI:3849598 (PMID:15240872)
(PMID:23685356), (PMID:25467444) 		RGD PMID:15240872 PMID:23685356 PMID:25467444 NCBI chr  X:157,751,651...157,757,796
Ensembl chr  Y:380,743...385,405
Ensembl chr  X:380,743...385,405 		JBrowse link
G Fbxo4 F-box protein 4 involved_in ISO
IEA 		(PMID:16275645)
GO_REF:0000107 		RGD
Ensembl		 PMID:16275645 GO_REF:0000107 NCBI chr 2:54,902,394...54,915,388
Ensembl chr 2:54,902,394...54,915,388 		JBrowse link
G Gch1 GTP cyclohydrolase 1 IMP RGD PMID:30690003 RGD:401717569 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:22,884,006...22,917,412 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) RGD PMID:23935072 NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:136,253,278...136,260,085 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D acts_upstream_of ISO
IEA 		(PMID:22633954)
GO_REF:0000107 		RGD
Ensembl		 PMID:22633954 GO_REF:0000107 NCBI chr14:9,918,630...9,938,072
Ensembl chr14:9,919,739...9,938,066 		JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein acts_upstream_of ISO (PMID:27510903) RGD PMID:27510903 NCBI chr16:27,604,228...27,634,963
Ensembl chr16:27,603,918...27,634,963 		JBrowse link
G Parn poly(A)-specific ribonuclease involved_in ISO
IEA 		(PMID:26482878), (PMID:26950371)
GO_REF:0000107 		RGD
Ensembl		 PMID:26482878 PMID:26950371 GO_REF:0000107 NCBI chr10:1,917,830...2,055,749
Ensembl chr10:1,917,830...2,055,722 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:12768206), (PMID:12781132), (PMID:17237768) RGD PMID:12768206 PMID:12781132 PMID:17237768 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
G Ptges3 prostaglandin E synthase 3 involved_in ISO (PMID:19740745) RGD PMID:19740745 NCBI chr 7:1,075,230...1,092,363
Ensembl chr 7:1,075,227...1,092,695 		JBrowse link
G Tcp1 t-complex 1 acts_upstream_of ISO
IEA 		(PMID:25467444)
GO_REF:0000107 		RGD
Ensembl		 PMID:25467444 GO_REF:0000107 NCBI chr 1:50,376,848...50,384,527
Ensembl chr 1:50,376,848...50,384,527 		JBrowse link
G Terc telomerase RNA component acts_upstream_of_or_within ISO MGI:1857930 (PMID:17982445) RGD PMID:17982445 NCBI chr 2:114,744,148...114,744,535 JBrowse link
G Tnks tankyrase involved_in ISO (PMID:11739745), (PMID:12782650), (PMID:18221737) RGD PMID:11739745 PMID:12782650 PMID:18221737 NCBI chr16:63,922,969...64,073,972
Ensembl chr16:63,928,281...64,079,282 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 acts_upstream_of ISO
IEA 		(PMID:23685356)
GO_REF:0000107 		RGD
Ensembl		 PMID:23685356 GO_REF:0000107 NCBI chr10:54,780,873...54,797,919
Ensembl chr10:54,773,282...54,797,651 		JBrowse link
positive regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO
IEA 		(PMID:17694070), (PMID:26586427)
GO_REF:0000117 		RGD
UniProt		 PMID:17694070 PMID:26586427 GO_REF:0000117 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO
IEA 		(PMID:21149580)
GO_REF:0000107 		RGD
Ensembl		 PMID:21149580 GO_REF:0000107 NCBI chr 2:149,006,089...149,044,192
Ensembl chr 2:149,006,089...149,044,191 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 involved_in IDA PMID:23184978 BHF-UCL PMID:23184978 RGD:11567256 NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:81,869,661...81,877,572 		JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein acts_upstream_of ISO (PMID:27510903) RGD PMID:27510903 NCBI chr16:27,604,228...27,634,963
Ensembl chr16:27,603,918...27,634,963 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IEA 		(PMID:23959892)
GO_REF:0000107 		RGD
Ensembl		 PMID:23959892 GO_REF:0000107 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
G Tnks tankyrase involved_in ISO (PMID:12782650) RGD PMID:12782650 NCBI chr16:63,922,969...64,073,972
Ensembl chr16:63,928,281...64,079,282 		JBrowse link
positive regulation of telomeric D-loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pot1 protection of telomeres 1 involved_in ISO (PMID:16030011) RGD PMID:16030011 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
positive regulation of telomeric loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IEA 		(PMID:22579284)
GO_REF:0000107 		RGD
Ensembl		 PMID:22579284 GO_REF:0000107 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
protection from non-homologous end joining at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in IEA
ISO 		GO_REF:0000107
(PMID:18185984) 		Ensembl
RGD		 PMID:18185984 GO_REF:0000107 NCBI chr19:50,496,634...50,499,397
Ensembl chr19:50,496,635...50,499,326 		JBrowse link
G Cdk2 cyclin dependent kinase 2 acts_upstream_of_or_within ISO (PMID:28216226) RGD PMID:28216226 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Dclre1b DNA cross-link repair 1B involved_in IEA
ISO
ISS 		GO_REF:0000107
GO_REF:0000117
(PMID:20551906), (PMID:20619712)
GO_REF:0000024
(PMID:16730175), (PMID:20479256) 		Ensembl
UniProt
RGD		 PMID:16730175 PMID:20479256 PMID:20551906 PMID:20619712 GO_REF:0000024 GO_REF:0000107 GO_REF:0000117 NCBI chr 2:193,998,350...194,006,873
Ensembl chr 2:193,998,354...194,006,864 		JBrowse link
G Nbn nibrin involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:28216226)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:28216226 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162 		JBrowse link
G Pot1 protection of telomeres 1 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		ComplexPortal:CPX-1993 (PMID:14690602), (PMID:17499040), (PMID:24095731)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000002
(PMID:20619712), (PMID:24120135)
MGI:3619525 (PMID:15968270)
GO_REF:0000033 		RGD
UniProt
Ensembl
InterPro
GO_Central		 PMID:14690602 PMID:15968270 PMID:17499040 PMID:20619712 PMID:24095731 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Terf2ip TERF2 interacting protein NOT|involved_in ISS
IEA
ISO
IBA 		GO_REF:0000024
GO_REF:0000107
(PMID:20339076), (PMID:20622869)
GO_REF:0000033 		UniProt
Ensembl
RGD
GO_Central		 PMID:20339076 PMID:20622869 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:56,886,211...56,893,300
Ensembl chr19:56,886,153...56,893,392 		JBrowse link
regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120 		JBrowse link
G Hdac8 histone deacetylase 8 involved_in ISO
IEA 		(PMID:16809764)
GO_REF:0000107 		RGD
Ensembl		 PMID:16809764 GO_REF:0000107 NCBI chr  X:71,425,240...71,632,865
Ensembl chr  X:71,394,928...71,632,865 		JBrowse link
G Lmna lamin A/C involved_in ISO (PMID:25399868) RGD PMID:25399868 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072 		JBrowse link
G Mcrs1 microspherule protein 1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 7:132,262,719...132,271,533
Ensembl chr 7:132,262,722...132,271,533 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO
ISS 		(PMID:17765874)
GO_REF:0000024 		RGD
UniProt		 PMID:17765874 GO_REF:0000024 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 1:190,716,759...190,722,307
Ensembl chr 1:190,714,490...190,722,307 		JBrowse link
G Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase involved_in ISO
IEA 		(PMID:17916692)
GO_REF:0000107 		RGD
Ensembl		 PMID:17916692 GO_REF:0000107 NCBI chr 1:181,876,134...181,977,894
Ensembl chr 1:181,876,134...181,977,894 		JBrowse link
G Smg5 SMG5 nonsense mediated mRNA decay factor involved_in ISO
IEA 		(PMID:16809764)
GO_REF:0000107 		RGD
Ensembl		 PMID:16809764 GO_REF:0000107 NCBI chr 2:176,102,812...176,129,925
Ensembl chr 2:176,102,794...176,129,924 		JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor involved_in ISO
IEA 		(PMID:12699629), (PMID:17916692)
GO_REF:0000107 		RGD
Ensembl		 PMID:12699629 PMID:17916692 GO_REF:0000107 NCBI chr10:60,284,628...60,512,738
Ensembl chr10:60,284,628...60,512,733 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IEA 		(PMID:22536324)
GO_REF:0000107 		RGD
Ensembl		 PMID:22536324 GO_REF:0000107 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Terf2ip TERF2 interacting protein involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:56,886,211...56,893,300
Ensembl chr19:56,886,153...56,893,392 		JBrowse link
G Upf1 UPF1, RNA helicase and ATPase involved_in ISO
IEA 		(PMID:17916692)
GO_REF:0000107 		RGD
Ensembl		 PMID:17916692 GO_REF:0000107 NCBI chr16:19,110,531...19,131,327
Ensembl chr16:19,110,538...19,131,327 		JBrowse link
G Ylpm1 YLP motif containing 1 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:15100092) 		GO_Central
RGD		 PMID:15100092 GO_REF:0000033 NCBI chr 6:110,373,371...110,449,578
Ensembl chr 6:110,373,686...110,449,578 		JBrowse link
regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO
IEA 		UniProtKB:Q9NUX5 (PMID:26586433)
GO_REF:0000117 		RGD
UniProt		 PMID:26586433 GO_REF:0000117 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO
IBA 		UniProtKB:Q13315 (PMID:26586433)
GO_REF:0000033 		RGD
GO_Central		 PMID:26586433 GO_REF:0000033 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
G Pot1b protection of telomeres 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:9,997,508...10,055,752
Ensembl chr 9:9,997,195...10,055,755 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IEA
IBA 		(PMID:19864690), (PMID:23685356)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:19864690 PMID:23685356 GO_REF:0000033 GO_REF:0000107 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Tnks tankyrase involved_in ISO (PMID:9822378) RGD PMID:9822378 NCBI chr16:63,922,969...64,073,972
Ensembl chr16:63,928,281...64,079,282 		JBrowse link
regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tinf2 TERF1 interacting nuclear factor 2 involved_in ISO (PMID:18669893) RGD PMID:18669893 NCBI chr15:33,140,611...33,146,930
Ensembl chr15:33,140,714...33,146,930 		JBrowse link
t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:22579284) RGD PMID:22579284 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120 		JBrowse link
G Nbn nibrin involved_in ISO
IEA 		(PMID:27918544)
GO_REF:0000107 		RGD
Ensembl		 PMID:27918544 GO_REF:0000107 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO
IEA 		(PMID:24012755)
GO_REF:0000117
(PMID:22579284) 		RGD
UniProt		 PMID:22579284 PMID:24012755 GO_REF:0000117 NCBI chr 1:190,716,759...190,722,307
Ensembl chr 1:190,714,490...190,722,307 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO
IEA 		(PMID:24012755)
GO_REF:0000117
GO_REF:0000107
(PMID:22579284) 		RGD
UniProt
Ensembl		 PMID:22579284 PMID:24012755 GO_REF:0000107 GO_REF:0000117 NCBI chr10:12,032,131...12,055,685
Ensembl chr10:12,033,048...12,055,650 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO
IEA
IBA 		(PMID:21903669)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:21903669 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:136,684,558...136,694,822 		JBrowse link
telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IEA
IBA 		UniProtKB:Q9NUX5 (PMID:17632522), (PMID:21852327), (PMID:25172512)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033 		RGD
UniProt
Ensembl
InterPro
GO_Central		 PMID:17632522 PMID:21852327 PMID:25172512 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr19:50,496,634...50,499,397
Ensembl chr19:50,496,635...50,499,326 		JBrowse link
G Dclre1b DNA cross-link repair 1B involved_in ISO
IEA 		(PMID:20479256)
GO_REF:0000107 		RGD
Ensembl		 PMID:20479256 GO_REF:0000107 NCBI chr 2:193,998,350...194,006,873
Ensembl chr 2:193,998,354...194,006,864 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 involved_in IDA PMID:15659580 UniProt PMID:15659580 RGD:10680046 NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:81,869,661...81,877,572 		JBrowse link
G Pot1 protection of telomeres 1 involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		UniProtKB:Q96AP0 (PMID:15657433), (PMID:17632522), (PMID:21852327), (PMID:27013236), (PMID:30586141), (PMID:35420632), (PMID:37140166)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:15657433 PMID:17632522 PMID:21852327 PMID:27013236 PMID:30586141 More... GO_REF:0000033 GO_REF:0000107 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
G Pot1b protection of telomeres 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:9,997,508...10,055,752
Ensembl chr 9:9,997,195...10,055,755 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:18710952) RGD PMID:18710952 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:98,544,954...98,762,108 		JBrowse link
G Spdya speedy/RINGO cell cycle regulator family member A acts_upstream_of_or_within ISO MGI:5888863 (PMID:28031483) RGD PMID:28031483 NCBI chr 6:29,619,415...29,675,030
Ensembl chr 6:29,626,542...29,674,951 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:256,336,916...256,371,143
Ensembl chr 1:256,315,367...256,370,736 		JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IEA 		(PMID:21852327)
GO_REF:0000107 		RGD
Ensembl		 PMID:21852327 GO_REF:0000107 NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:8,226,345...8,255,753 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IEA 		(PMID:12768206), (PMID:14690602), (PMID:15657433), (PMID:21852327)
GO_REF:0000107 		RGD
Ensembl		 PMID:12768206 PMID:14690602 PMID:15657433 PMID:21852327 GO_REF:0000107 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Terf2ip TERF2 interacting protein involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:56,886,211...56,893,300
Ensembl chr19:56,886,153...56,893,392 		JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 involved_in ISO
IEA 		(PMID:15133513), (PMID:18443218), (PMID:21852327)
GO_REF:0000002 		RGD
InterPro		 PMID:15133513 PMID:18443218 PMID:21852327 GO_REF:0000002 NCBI chr15:33,140,611...33,146,930
Ensembl chr15:33,140,714...33,146,930 		JBrowse link
telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:28216226)
GO_REF:0000107 		RGD
Ensembl		 PMID:28216226 GO_REF:0000107 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Nbn nibrin involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:28216226) 		UniProt
Ensembl
RGD		 PMID:28216226 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162 		JBrowse link
G Pot1 protection of telomeres 1 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:28216226)
GO_REF:0000107 		RGD
Ensembl		 PMID:28216226 GO_REF:0000107 NCBI chr 1:210,914,576...210,918,193
Ensembl chr 1:210,914,567...210,918,193 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO
IEA 		(PMID:15583028)
GO_REF:0000107 		RGD
Ensembl		 PMID:15583028 GO_REF:0000107 NCBI chr 3:56,963,840...57,017,106
Ensembl chr 3:56,963,854...57,017,106 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IEA 		(PMID:22579284)
GO_REF:0000107 		RGD
Ensembl		 PMID:22579284 GO_REF:0000107 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
telomere maintenance via base-excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 involved_in ISO
IEA 		(PMID:24703901)
GO_REF:0000107 		RGD
Ensembl		 PMID:24703901 GO_REF:0000107 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329 		JBrowse link
telomere maintenance via recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q13207 (PMID:21076401) 		Ensembl
RGD		 PMID:21076401 GO_REF:0000107 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194 		JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO
IEA
ISS 		(PMID:17589526)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:17589526 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:92,825,568...93,071,037
Ensembl chr 7:92,825,587...93,054,326 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Rad51 RAD51 recombinase involved_in ISO
IEA 		UniProtKB:P02340 (PMID:21076401)
GO_REF:0000107 		RGD
Ensembl		 PMID:21076401 GO_REF:0000107 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469 		JBrowse link
G Rad51c RAD51 paralog C involved_in ISO
IEA 		UniProtKB:P02340 (PMID:21076401)
GO_REF:0000107 		RGD
Ensembl		 PMID:21076401 GO_REF:0000107 NCBI chr10:72,702,299...72,728,980
Ensembl chr10:72,702,299...72,729,143 		JBrowse link
G Rad51d RAD51 paralog D involved_in ISO (PMID:15109494) RGD PMID:15109494 NCBI chr10:68,303,350...68,322,002
Ensembl chr10:68,238,273...68,321,902 		JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107
G Smc5 structural maintenance of chromosomes 5 involved_in ISO (PMID:17589526) RGD PMID:17589526 NCBI chr 1:230,195,894...230,265,677
Ensembl chr 1:230,195,894...230,265,621 		JBrowse link
G Smc6 structural maintenance of chromosomes 6 involved_in ISO
IEA 		(PMID:17589526)
GO_REF:0000107 		RGD
Ensembl		 PMID:17589526 GO_REF:0000107 NCBI chr 6:39,697,810...39,752,275
Ensembl chr 6:39,697,811...39,752,279 		JBrowse link
G Tep1 telomerase associated protein 1 involved_in ISO
IBA
IEA 		(PMID:10810353)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:10810353 GO_REF:0000033 GO_REF:0000107 NCBI chr15:26,519,429...26,567,073
Ensembl chr15:26,519,431...26,567,073 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO
IEA
IBA 		(PMID:15507207)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:15507207 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:136,684,558...136,694,822 		JBrowse link
telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dna2 DNA replication helicase/nuclease 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr20:25,660,339...25,689,285 JBrowse link
G Slc25a16 solute carrier family 25 member 16 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr20:25,659,847...25,717,080
Ensembl chr20:25,660,339...25,689,285
Ensembl chr20:25,660,339...25,689,285 		JBrowse link
G Upf1 UPF1, RNA helicase and ATPase involved_in ISO
IEA 		(PMID:21829167)
GO_REF:0000107 		RGD
Ensembl		 PMID:21829167 GO_REF:0000107 NCBI chr16:19,110,531...19,131,327
Ensembl chr16:19,110,538...19,131,327 		JBrowse link
telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in IEA
ISO 		GO_REF:0000107
GO_REF:0000002
(PMID:17237768) 		Ensembl
InterPro
RGD		 PMID:17237768 GO_REF:0000002 GO_REF:0000107 NCBI chr19:50,496,634...50,499,397
Ensembl chr19:50,496,635...50,499,326 		JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 involved_in ISS
ISO 		GO_REF:0000024
GO:0090669 (PMID:26950371), (PMID:29695869) 		UniProt
RGD		 PMID:26950371 PMID:29695869 GO_REF:0000024 NCBI chr  X:157,751,651...157,757,796
Ensembl chr  Y:380,743...385,405
Ensembl chr  X:380,743...385,405 		JBrowse link
G Gar1 GAR1 ribonucleoprotein involved_in ISS
ISO 		GO_REF:0000024
(PMID:29695869) 		UniProt
RGD		 PMID:29695869 GO_REF:0000024 NCBI chr 2:221,049,471...221,056,749
Ensembl chr 2:221,049,473...221,056,749 		JBrowse link
G Hmbox1 homeobox containing 1 involved_in ISO
IEA 		(PMID:23685356)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:23685356 GO_REF:0000107 GO_REF:0000117 NCBI chr15:43,243,503...43,376,011
Ensembl chr15:43,222,470...43,376,011 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 acts_upstream_of_positive_effect ISO
IEA 		(PMID:10197982)
GO_REF:0000107 		RGD
Ensembl		 PMID:10197982 GO_REF:0000107 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 acts_upstream_of_positive_effect ISO
IEA 		(PMID:10197982)
GO_REF:0000107 		RGD
Ensembl		 PMID:10197982 GO_REF:0000107 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926 		JBrowse link
G Nhp2 NHP2 ribonucleoprotein involved_in ISO
IEA 		(PMID:29695869)
GO_REF:0000107 		RGD
Ensembl		 PMID:29695869 GO_REF:0000107 NCBI chr10:36,378,020...36,381,362
Ensembl chr10:36,377,997...36,381,354 		JBrowse link
G Nop10 NOP10 ribonucleoprotein involved_in ISO (PMID:29695869) RGD PMID:29695869 NCBI chr 3:119,521,255...119,522,340
Ensembl chr 3:119,521,255...119,522,340 		JBrowse link
G Parp4 poly (ADP-ribose) polymerase family, member 4 NOT|acts_upstream_of_or_within ISO MGI:109573 (PMID:15169895) RGD PMID:15169895 NCBI chr15:34,806,203...34,908,492
Ensembl chr15:34,816,701...34,944,433 		JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 acts_upstream_of_or_within ISO (PMID:11701125) RGD PMID:11701125 NCBI chr15:42,273,805...42,333,047
Ensembl chr15:42,273,799...42,333,047 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:12768206), (PMID:16043710), (PMID:27013236), (PMID:30586141), (PMID:35420632), (PMID:37140166) RGD PMID:12768206 PMID:16043710 PMID:27013236 PMID:30586141 PMID:35420632 More... NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
G Ptges3 prostaglandin E synthase 3 involved_in
acts_upstream_of_positive_effect 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:10197982) 		GO_Central
Ensembl
RGD		 PMID:10197982 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:1,075,230...1,092,363
Ensembl chr 7:1,075,227...1,092,695 		JBrowse link
G Ptges3l1 prostaglandin E synthase 3-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:46,092,665...46,101,937
Ensembl chr  X:46,092,206...46,107,019 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO
IBA
IEA
ISS 		(PMID:9705271)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024 		RGD
GO_Central
Ensembl
UniProt		 PMID:9705271 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Rpa1 replication protein A1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:60,647,185...60,698,279
Ensembl chr10:60,647,185...60,698,279 		JBrowse link
G Tep1 telomerase associated protein 1 NOT|acts_upstream_of_or_within ISO MGI:2685589 (PMID:15169895) RGD PMID:15169895 NCBI chr15:26,519,429...26,567,073
Ensembl chr15:26,519,431...26,567,073 		JBrowse link
G Terc telomerase RNA component acts_upstream_of
involved_in 		TAS
ISO 		MGI:1857930 (PMID:17982445)
(PMID:17940095), (PMID:19701182), (PMID:9443919) 		RGD PMID:9443919 PMID:17940095 PMID:17982445 PMID:19701182 PMID:10423530 RGD:1299555 NCBI chr 2:114,744,148...114,744,535 JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IEA 		(PMID:9034193)
GO_REF:0000107
(PMID:23685356) 		RGD
Ensembl		 PMID:9034193 PMID:23685356 GO_REF:0000107 NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:8,226,345...8,255,753 		JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO
IEA
IBA
ISS 		(PMID:16043710), (PMID:17940095), (PMID:19701182), (PMID:21531765), (PMID:29695869), (PMID:9443919), (PMID:9454332)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024 		RGD
Ensembl
GO_Central
UniProt		 PMID:9443919 PMID:9454332 PMID:16043710 PMID:17940095 PMID:19701182 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:29695869), (PMID:29804836) 		UniProt
Ensembl
RGD		 PMID:29695869 PMID:29804836 GO_REF:0000024 GO_REF:0000107 NCBI chr10:54,780,873...54,797,919
Ensembl chr10:54,773,282...54,797,651 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:19188702) RGD PMID:19188702 NCBI chr 9:81,404,507...81,493,293
Ensembl chr 9:81,375,863...81,493,293 		JBrowse link
telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctc1 CST telomere replication complex component 1 involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
MGI:5427642 (PMID:22531781) 		GO_Central
Ensembl
RGD		 PMID:22531781 GO_REF:0000033 GO_REF:0000107 NCBI chr10:54,212,537...54,234,146
Ensembl chr10:54,207,083...54,234,147 		JBrowse link
G Dclre1b DNA cross-link repair 1B involved_in IEA
ISO 		GO_REF:0000107
(PMID:20479256) 		Ensembl
RGD		 PMID:20479256 GO_REF:0000107 NCBI chr 2:193,998,350...194,006,873
Ensembl chr 2:193,998,354...194,006,864 		JBrowse link
G Rad51 RAD51 recombinase involved_in ISO
IEA 		UniProtKB:P02340 (PMID:21076401)
GO_REF:0000107 		RGD
Ensembl		 PMID:21076401 GO_REF:0000107 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr 1:190,716,759...190,722,307
Ensembl chr 1:190,714,490...190,722,307 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in IEA
IBA
ISS
ISO 		GO_REF:0000104
GO_REF:0000033
GO_REF:0000024
(PMID:19648609) 		UniProt
GO_Central
RGD		 PMID:19648609 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:256,336,916...256,371,143
Ensembl chr 1:256,315,367...256,370,736 		JBrowse link
G Terf2ip TERF2 interacting protein involved_in ISS
IEA
ISO
IBA 		GO_REF:0000024
GO_REF:0000117
GO_REF:0000107
(PMID:20339076), (PMID:20622869)
GO_REF:0000033
GO_REF:0000104 		UniProt
Ensembl
RGD
GO_Central		 PMID:20339076 PMID:20622869 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr19:56,886,211...56,893,300
Ensembl chr19:56,886,153...56,893,392 		JBrowse link
G Zbtb48 zinc finger and BTB domain containing 48 involved_in ISO
IEA 		(PMID:28082411), (PMID:28500257)
GO_REF:0000107 		RGD
Ensembl		 PMID:28082411 PMID:28500257 GO_REF:0000107 NCBI chr 5:167,807,965...167,816,332
Ensembl chr 5:167,807,966...167,816,313 		JBrowse link
telomere maintenance via telomere trimming term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nbn nibrin involved_in ISO
IEA 		UniProtKB:O43542 (PMID:27918544)
GO_REF:0000107 		RGD
Ensembl		 PMID:27918544 GO_REF:0000107 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO
IEA 		UniProtKB:O60934 (PMID:27918544)
GO_REF:0000107 		RGD
Ensembl		 PMID:27918544 GO_REF:0000107 NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:136,684,558...136,694,822 		JBrowse link
telomeric 3' overhang formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dclre1b DNA cross-link repair 1B involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:20551906), (PMID:20619712)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:20551906 PMID:20619712 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:193,998,350...194,006,873
Ensembl chr 2:193,998,354...194,006,864 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in ISO (PMID:16374507) RGD PMID:16374507 NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:19,913,772...19,961,904 		JBrowse link
G Nbn nibrin involved_in ISO
IEA 		(PMID:16374507)
GO_REF:0000107 		RGD
Ensembl		 PMID:16374507 GO_REF:0000107 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO
IEA 		(PMID:16374507)
GO_REF:0000107 		RGD
Ensembl		 PMID:16374507 GO_REF:0000107 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
telomeric D-loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase involved_in ISO
IEA 		(PMID:16030011), (PMID:19734539)
GO_REF:0000107 		RGD
Ensembl		 PMID:16030011 PMID:19734539 GO_REF:0000107 NCBI chr 1:143,819,072...143,905,300
Ensembl chr 1:143,819,090...143,905,210 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO UniProtKB:O94761 (PMID:22039056) RGD PMID:22039056 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
G Recql4 RecQ like helicase 4 involved_in ISO UniProtKB:P54274|UniProtKB:Q14191|UniProtKB:Q15554|UniProtKB:Q9NUX5 (PMID:22039056) RGD PMID:22039056 NCBI chr 7:110,304,092...110,311,426
Ensembl chr 7:110,304,094...110,311,258 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr 1:190,716,759...190,722,307
Ensembl chr 1:190,714,490...190,722,307 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO
IEA 		(PMID:24012755)
GO_REF:0000107 		RGD
Ensembl		 PMID:24012755 GO_REF:0000107 NCBI chr10:12,032,131...12,055,685
Ensembl chr10:12,033,048...12,055,650 		JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IEA 		UniProtKB:O94761 (PMID:22039056)
GO_REF:0000107 		RGD
Ensembl		 PMID:22039056 GO_REF:0000107 NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:8,226,345...8,255,753 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IEA
IBA 		UniProtKB:O94761 (PMID:22039056)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:22039056 GO_REF:0000033 GO_REF:0000107 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Wrn WRN RecQ like helicase involved_in ISO UniProtKB:O94761 (PMID:15200954), (PMID:16030011), (PMID:19734539), (PMID:22039056), (PMID:26420422) RGD PMID:15200954 PMID:16030011 PMID:19734539 PMID:22039056 PMID:26420422 NCBI chr16:65,466,552...65,602,951
Ensembl chr16:65,456,254...65,602,951 		JBrowse link
telomeric DNA-containing double minutes formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO
IEA 		(PMID:14690602)
GO_REF:0000107 		RGD
Ensembl		 PMID:14690602 GO_REF:0000107 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 2:22,686,506...22,932,929
Ensembl chr 2:22,686,508...22,933,160 		JBrowse link
telomeric loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IEA
IBA 		(PMID:25620558)
GO_REF:0000117
GO_REF:0000107
(PMID:22579284), (PMID:24115439)
GO_REF:0000033 		RGD
UniProt
Ensembl
GO_Central		 PMID:22579284 PMID:24115439 PMID:25620558 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
telomeric loop formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dclre1b DNA cross-link repair 1B involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:20619712)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:20619712 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:193,998,350...194,006,873
Ensembl chr 2:193,998,354...194,006,864 		JBrowse link
G Pot1 protection of telomeres 1 NOT|involved_in ISO UniProtKB:H7BX60 (PMID:24120135) RGD PMID:24120135 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
G Terf1 telomeric repeat binding factor 1 NOT|involved_in ISO (PMID:24120135) RGD PMID:24120135 NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:8,226,345...8,255,753 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IEA
IBA 		(PMID:10338214)
GO_REF:0000117
GO_REF:0000107
(PMID:24120135)
GO_REF:0000033 		RGD
UniProt
Ensembl
GO_Central		 PMID:10338214 PMID:24120135 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Terf2ip TERF2 interacting protein NOT|involved_in ISO (PMID:24120135) RGD PMID:24120135 NCBI chr19:56,886,211...56,893,300
Ensembl chr19:56,886,153...56,893,392 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20635
    cellular process 19619
      metabolic process 12226
        macromolecule metabolic process 10050
          nucleic acid metabolic process 5323
            DNA metabolic process 999
              telomere maintenance 153
                negative regulation of telomere maintenance + 37
                positive regulation of telomere maintenance + 70
                regulation of telomere maintenance + 101
                telomere capping + 28
                telomere maintenance in response to DNA damage + 29
                telomere maintenance via recombination + 16
                telomere maintenance via semi-conservative replication + 5
                telomere maintenance via telomere lengthening + 68
                telomere maintenance via telomere trimming + 8
                telomeric loop disassembly + 9
                telomeric loop formation + 5
Path 2
Term Annotations click to browse term
  biological_process 20635
    cellular process 19619
      metabolic process 12226
        primary metabolic process 10825
          nucleobase-containing compound metabolic process 5957
            nucleic acid metabolic process 5323
              DNA metabolic process 999
                telomere maintenance 153
                  negative regulation of telomere maintenance + 37
                  positive regulation of telomere maintenance + 70
                  regulation of telomere maintenance + 101
                  telomere capping + 28
                  telomere maintenance in response to DNA damage + 29
                  telomere maintenance via recombination + 16
                  telomere maintenance via semi-conservative replication + 5
                  telomere maintenance via telomere lengthening + 68
                  telomere maintenance via telomere trimming + 8
                  telomeric loop disassembly + 9
                  telomeric loop formation + 5
paths to the root