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ONTOLOGY REPORT - ANNOTATIONS

Term:MIS12/MIND type complex
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Accession:GO:0000444 term browser browse the term
Definition:A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1.
Synonyms:exact_synonym: MIND complex
 narrow_synonym: Mis12 complex
 related_synonym: Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex;   nuclear MIS12/MIND complex
 alt_id: GO:0000818


show annotations for term's descendants           Sort by:
MIS12/MIND type complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsn1 DSN1 component of MIS12 kinetochore complex part_of ISO
IBA		 (PMID:16585270), (PMID:20819937), (PMID:27881301)
GO_REF:0000033		 RGD
GO_Central		 PMID:16585270 PMID:20819937 PMID:27881301 GO_REF:0000033 NCBI chr 3:145,652,741...145,668,025
Ensembl chr 3:145,652,737...145,665,856 		JBrowse link
G Mis12 MIS12 kinetochore complex component part_of IEA
IBA
ISS
ISO		 GO_REF:0000107
GO_REF:0000033
GO_REF:0000024
(PMID:16585270), (PMID:20819937), (PMID:27881301)		 Ensembl
GO_Central
UniProt
RGD		 PMID:16585270 PMID:20819937 PMID:27881301 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:55,739,741...55,747,915
Ensembl chr10:55,739,564...55,751,068 		JBrowse link
G Nsl1 NSL1 component of MIS12 kinetochore complex part_of ISO
IBA		 (PMID:16585270), (PMID:20819937), (PMID:27881301)
GO_REF:0000033		 RGD
GO_Central		 PMID:16585270 PMID:20819937 PMID:27881301 GO_REF:0000033 NCBI chr13:102,649,050...102,674,059
Ensembl chr13:102,649,058...102,674,054 		JBrowse link
G Pmf1 polyamine-modulated factor 1 part_of ISO
IBA		 (PMID:16585270), (PMID:20819937), (PMID:27881301)
GO_REF:0000033		 RGD
GO_Central		 PMID:16585270 PMID:20819937 PMID:27881301 GO_REF:0000033 NCBI chr 2:173,848,074...173,868,272
Ensembl chr 2:173,848,074...173,868,270 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20833
    protein-containing complex 6558
      outer kinetochore 24
        MIS12/MIND type complex 4
Path 2
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      organelle 13975
        membraneless organelle 5268
          intracellular membraneless organelle 5268
            chromosome 1385
              chromosomal region 334
                chromosome, centromeric region 233
                  condensed chromosome, centromeric region 167
                    kinetochore 155
                      outer kinetochore 24
                        MIS12/MIND type complex 4
paths to the root