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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:MIS12/MIND type complex
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Accession:GO:0000444 term browser browse the term
Definition:A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1.
Synonyms:exact_synonym: MIND complex
 narrow_synonym: Mis12 complex
 related_synonym: Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex;   nuclear MIS12/MIND complex
 alt_id: GO:0000818



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MIS12/MIND type complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BGLAP bone gamma-carboxyglutamate protein part_of ISO (PMID:16585270), (PMID:20819937), (PMID:27881301) UniProt PMID:16585270 PMID:20819937 PMID:27881301 NCBI chr 4:93,807,703...93,808,806
Ensembl chr 4:93,807,706...93,808,968
JBrowse link
G DSN1 DSN1 component of MIS12 kinetochore complex part_of IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr17:39,992,769...40,017,388
Ensembl chr17:39,990,624...40,017,365
JBrowse link
G MIS12 MIS12 kinetochore complex component part_of IEA Ensembl GO_REF:0000107 NCBI chr12:51,505,376...51,508,337
Ensembl chr12:51,505,381...51,507,943
JBrowse link
G NSL1 NSL1 component of MIS12 kinetochore complex part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:130,599,901...130,668,935
Ensembl chr 9:130,622,331...130,668,936
JBrowse link
G PMF1 polyamine modulated factor 1 part_of IEA InterPro GO_REF:0000002 NCBI chr 4:93,810,863...93,836,786
Ensembl chr 4:93,810,507...93,837,652
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18111
    protein-containing complex 5706
      outer kinetochore 24
        MIS12/MIND type complex 5
Path 2
Term Annotations click to browse term
  cellular_component 18111
    cellular anatomical entity 17874
      organelle 11821
        non-membrane-bounded organelle 4383
          intracellular non-membrane-bounded organelle 4382
            chromosome 1228
              chromosomal region 323
                chromosome, centromeric region 223
                  condensed chromosome, centromeric region 162
                    kinetochore 151
                      outer kinetochore 24
                        MIS12/MIND type complex 5
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