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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:MIS12/MIND type complex
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Accession:GO:0000444 term browser browse the term
Definition:A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1.
Synonyms:exact_synonym: MIND complex
 narrow_synonym: Mis12 complex
 related_synonym: Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex;   nuclear MIS12/MIND complex
 alt_id: GO:0000818


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MIS12/MIND type complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsn1 DSN1 component of MIS12 kinetochore complex part_of ISO (PMID:16585270), (PMID:20819937), (PMID:27881301) UniProt PMID:16585270 PMID:20819937 PMID:27881301 NCBI chrNW_004955422:24,876,340...24,896,435 JBrowse link
G Mis12 MIS12 kinetochore complex component part_of ISO (PMID:16585270), (PMID:20819937), (PMID:27881301) UniProt PMID:16585270 PMID:20819937 PMID:27881301 NCBI chrNW_004955467:10,837,570...10,842,131
Ensembl chrNW_004955467:10,837,832...10,842,123
JBrowse link
G Nsl1 NSL1 component of MIS12 kinetochore complex part_of ISO (PMID:16585270), (PMID:20819937), (PMID:27881301) UniProt PMID:16585270 PMID:20819937 PMID:27881301 NCBI chrNW_004955406:4,764,439...4,798,499
Ensembl chrNW_004955406:4,764,130...4,799,204
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12475
    protein-containing complex 4408
      outer kinetochore 21
        MIS12/MIND type complex 3
Path 2
Term Annotations click to browse term
  cellular_component 12475
    cellular anatomical entity 12314
      organelle 9716
        non-membrane-bounded organelle 3638
          intracellular non-membrane-bounded organelle 3637
            chromosome 1027
              chromosomal region 274
                chromosome, centromeric region 184
                  condensed chromosome, centromeric region 140
                    kinetochore 130
                      outer kinetochore 21
                        MIS12/MIND type complex 3
paths to the root