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Term:MIS12/MIND type complex
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Accession:GO:0000444 term browser browse the term
Definition:A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1.
Synonyms:exact_synonym: MIND complex
 narrow_synonym: Mis12 complex
 related_synonym: Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex;   nuclear MIS12/MIND complex
 alt_id: GO:0000818

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MIS12/MIND type complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsn1 DSN1 component of MIS12 kinetochore complex part_of ISO (PMID:16585270) RGD PMID:16585270 NCBI chr 3:145,652,741...145,668,025
Ensembl chr 3:145,652,737...145,665,856
JBrowse link
G Mis12 MIS12 kinetochore complex component part_of ISO (PMID:16585270) RGD PMID:16585270 NCBI chr10:55,739,590...55,747,915
Ensembl chr10:55,739,564...55,751,068
JBrowse link
G Nsl1 NSL1 component of MIS12 kinetochore complex part_of ISO
RGD PMID:16585270 PMID:21873635 RGD:13792537 NCBI chr13:102,649,050...102,674,059
Ensembl chr13:102,649,058...102,674,054
JBrowse link
G Pmf1 polyamine-modulated factor 1 part_of ISO (PMID:16585270) RGD PMID:16585270 NCBI chr 2:173,848,074...173,868,272
Ensembl chr 2:173,848,074...173,868,270
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20082
    protein-containing complex 6449
      MIS12/MIND type complex 4
Path 2
Term Annotations click to browse term
  cellular_component 20082
    cellular anatomical entity 19921
      organelle 13177
        non-membrane-bounded organelle 5087
          intracellular non-membrane-bounded organelle 5086
            chromosome 1324
              chromosomal region 331
                chromosome, centromeric region 232
                  condensed chromosome, centromeric region 155
                    kinetochore 144
                      inner kinetochore 8
                        MIS12/MIND type complex 4
paths to the root