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ONTOLOGY REPORT - ANNOTATIONS


Term:transcription factor TFIIH core complex
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Accession:GO:0000439 term browser browse the term
Definition:The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD.
Synonyms:exact_synonym: SSL2-core TFIIH complex;   core TFIIH complex
 alt_id: GO:0000441


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transcription factor TFIIH core complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063323.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:28,557,633...28,557,848 JBrowse link
G Ccnh cyclin H ISO
IEA
(PMID:8692841), (PMID:8692842)
GO_REF:0000107
RGD
Ensembl
PMID:8692841, PMID:8692842 GO_REF:0000107 NCBI chr 2:13,593,100...13,613,910
Ensembl chr 2:13,593,100...13,613,910
JBrowse link
G Cdk7 cyclin-dependent kinase 7 ISO
IEA
(PMID:8692841)
GO_REF:0000107
RGD
Ensembl
PMID:8692841 GO_REF:0000107 NCBI chr 2:30,710,642...30,735,522
Ensembl chr 2:30,710,643...30,735,514
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit IDA
ISO
(PMID:8692841), (PMID:8692842) RGD PMID:8692841, PMID:8692842, PMID:8855220 RGD:1642642 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit IDA
ISO
(PMID:8692841), (PMID:8692842) RGD PMID:8692841, PMID:8692842, PMID:8855220 RGD:1642642 NCBI chr18:25,037,668...25,068,380
Ensembl chr18:25,037,625...25,068,389
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 ISO
IBA
(PMID:8692841)
PMID:21873635
RGD PMID:8692841, PMID:21873635 RGD:13792537 NCBI chr 1:102,849,618...102,877,939
Ensembl chr 1:102,849,889...102,877,944
JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:37,427,556...37,444,027
Ensembl chr12:37,427,546...37,444,282
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:3,582,688...3,588,373
Ensembl chr20:3,582,742...3,588,375
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:46,978,345...46,985,032
Ensembl chr 1:46,978,458...46,985,032
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase ISO
IEA
(PMID:8692841)
GO_REF:0000107
RGD
Ensembl
PMID:8692841 GO_REF:0000107 NCBI chr 6:95,995,341...96,153,331
Ensembl chr 6:96,007,805...96,153,330
JBrowse link
core TFIIH complex portion of holo TFIIH complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2h2 general transcription factor IIH subunit 2 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 2:30,494,718...30,522,716
Ensembl chr 2:30,494,825...30,522,727
JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 ISO
ISS
(PMID:27193682)
GO_REF:0000024
RGD
UniProt
PMID:27193682 GO_REF:0000024 NCBI chr12:37,427,556...37,444,027
Ensembl chr12:37,427,546...37,444,282
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 ISO (PMID:27193682) RGD PMID:27193682 NCBI chr20:3,582,688...3,588,373
Ensembl chr20:3,582,742...3,588,375
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      transcription regulator complex 434
        RNA polymerase II transcription regulator complex 162
          transcription factor TFIIH core complex 11
            core TFIIH complex portion of NEF3 complex 0
            core TFIIH complex portion of holo TFIIH complex 3
Path 2
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      organelle 13258
        membrane-bounded organelle 11449
          intracellular membrane-bounded organelle 10704
            nucleus 7183
              transcription factor TFIIH core complex 11
                core TFIIH complex portion of NEF3 complex 0
                core TFIIH complex portion of holo TFIIH complex 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.