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ONTOLOGY REPORT - ANNOTATIONS


Term:mitophagy
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Accession:GO:0000423 term browser browse the term
Definition:The selective autophagy process in which a mitochondrion is degraded by macroautophagy.
Comment:Note that this terms refers to the macroautophagy process and is named by common usage. Be aware that there are a separate micromitophagy and mitophagy by induced vacuole formation processes.
Synonyms:exact_synonym: macromitophagy
 xref: Wikipedia:Mitophagy



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mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 involved_in ISO (PMID:38081847) RGD PMID:38081847 NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699
JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO
IBA
UniProtKB:O60260|UniProtKB:Q99MQ3 (PMID:21753002), (PMID:25215947)
GO_REF:0000033
RGD
GO_Central
PMID:21753002 PMID:25215947 GO_REF:0000033 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Arfip2 ARF interacting protein 2 involved_in ISO
ISS
(PMID:33773106)
GO_REF:0000024
RGD
UniProt
PMID:33773106 GO_REF:0000024 NCBI chr 1:159,974,255...159,980,398
Ensembl chr 1:159,974,201...159,980,336
JBrowse link
G Arhgap26 Rho GTPase activating protein 26 involved_in ISO (PMID:38081847) RGD PMID:38081847 NCBI chr18:30,835,806...31,237,945
Ensembl chr18:30,838,671...31,235,194
JBrowse link
G Atg10 autophagy related 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
JBrowse link
G Atg13 autophagy related 13 involved_in IBA
ISO
GO_REF:0000033
(PMID:21855797)
GO_Central
RGD
PMID:21855797 GO_REF:0000033 NCBI chr 3:77,647,069...77,681,028
Ensembl chr 3:77,645,790...77,681,043
JBrowse link
G Atg14 autophagy related 14 involved_in ISO
IBA
(PMID:23878393)
GO_REF:0000033
RGD
GO_Central
PMID:23878393 GO_REF:0000033 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113
JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:104,665,345...104,765,271
Ensembl chr  X:104,665,345...104,765,268
JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase involved_in ISO
IBA
IEA
(PMID:33773106)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:33773106 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103
JBrowse link
G Atg4c autophagy related 4C, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:113,867,218...113,935,534
Ensembl chr 5:113,867,092...113,934,830
JBrowse link
G Atg4d autophagy related 4D, cysteine peptidase involved_in ISO
IBA
(PMID:33773106)
GO_REF:0000033
RGD
GO_Central
PMID:33773106 GO_REF:0000033 NCBI chr 8:19,807,733...19,817,321
Ensembl chr 8:19,807,766...19,817,321
JBrowse link
G Atg5 autophagy related 5 involved_in IEA
IBA
GO_REF:0000107
GO_REF:0000033
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 involved_in IEA
ISO
GO_REF:0000107
(PMID:20080761)
UniProtKB:Q9BXM7 (PMID:19279012)
Ensembl
RGD
PMID:19279012 PMID:20080761 GO_REF:0000107 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atg9a autophagy related 9A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:76,677,403...76,688,050
Ensembl chr 9:76,677,404...76,687,986
JBrowse link
G Atg9b autophagy related 9B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:10,784,934...10,793,832
Ensembl chr 4:10,786,114...10,793,651
JBrowse link
G Bcl2l13 Bcl2-like 13 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:31266807)
GO_REF:0000107
RGD
Ensembl
PMID:31266807 GO_REF:0000107 NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:154,056,127...154,108,985
JBrowse link
G Becn1 beclin 1 involved_in ISO
IBA
(PMID:23878393), (PMID:25215947)
GO_REF:0000033
RGD
GO_Central
PMID:23878393 PMID:25215947 GO_REF:0000033 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Becn2 beclin 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:87,842,980...87,892,410
Ensembl chr13:87,844,531...87,845,787
JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO (PMID:22505714) RGD PMID:22505714 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Clec16a C-type lectin domain containing 16A involved_in ISO (PMID:35604110) RGD PMID:35604110 NCBI chr10:4,927,799...5,123,749
Ensembl chr10:4,928,030...5,123,578
JBrowse link
G Ctsk cathepsin K involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha involved_in ISO
ISS
(PMID:38340717)
GO_REF:0000024
RGD
UniProt
PMID:38340717 GO_REF:0000024 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Fundc1 FUN14 domain containing 1 involved_in ISO UniProtKB:P09936 (PMID:34244144) RGD PMID:34244144 NCBI chr  X:5,083,635...5,100,293
Ensembl chr  X:5,083,617...5,100,284
JBrowse link
G Gabarap GABA type A receptor-associated protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628
JBrowse link
G Gabarapl3 GABA type A receptor associated protein like 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:89,246,175...89,247,132
Ensembl chr 8:89,246,195...89,247,139
JBrowse link
G Gabarapl4 gamma-aminobutyric acid receptor associated protein like 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:55,052,756...55,053,109
Ensembl chr19:55,052,756...55,053,109
JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:23707074) RGD PMID:23707074 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Lrba LPS responsive beige-like anchor protein involved_in ISO (PMID:33773106) RGD PMID:33773106 NCBI chr 2:171,623,668...172,202,576
Ensembl chr 2:171,621,507...172,202,724
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
UniProtKB:Q9BXM7 (PMID:19279012), (PMID:28017329)
UniProt
GO_Central
RGD
PMID:19279012 PMID:28017329 GO_REF:0000024 GO_REF:0000033 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690
JBrowse link
G Nipsnap1 nipsnap homolog 1 involved_in ISO (PMID:30982665) RGD PMID:30982665 NCBI chr14:79,734,234...79,758,101
Ensembl chr14:79,734,209...79,758,098
JBrowse link
G Nipsnap2 nipsnap homolog 2 involved_in ISO (PMID:30982665) RGD PMID:30982665 NCBI chr12:26,906,068...26,944,201
Ensembl chr12:26,911,723...26,944,166
JBrowse link
G Nipsnap3a nipsnap homolog 3A (C. elegans) involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 5:67,613,993...67,625,067
Ensembl chr 5:67,614,036...67,669,700
JBrowse link
G Nipsnap3b nipsnap homolog 3B involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 5:67,637,644...67,669,698
Ensembl chr 5:67,614,036...67,669,700
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA
ISO
GO_REF:0000107
(PMID:33406421)
Ensembl
RGD
PMID:33406421 GO_REF:0000107 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146
JBrowse link
G Phb2 prohibitin 2 involved_in ISO
IEA
ISS
(PMID:28017329)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:28017329 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IMP
ISO
UniProtKB:Q8CGY8 (PMID:33406421), (PMID:38081847) RGD PMID:33406421 PMID:38081847 PMID:25154397 RGD:12904014 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within
IDA
IBA
ISO
PMID:20457763
GO_REF:0000033
(PMID:23685073), (PMID:28017329)
MGI:1921624 (PMID:24949970)
GO_Central
RGD
PMID:23685073 PMID:24949970 PMID:28017329 PMID:20457763 GO_REF:0000033, RGD:10047224 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Retreg1 reticulophagy regulator 1 acts_upstream_of_or_within ISO (PMID:31446166) RGD PMID:31446166 NCBI chr 2:76,335,609...76,474,817
Ensembl chr 2:76,335,609...76,493,898
JBrowse link
G Rimoc1 RAB7A interacting MON1-CCZ1 complex subunit 1 involved_in ISO (PMID:34432599) RGD PMID:34432599 NCBI chr 2:53,189,787...53,203,981
Ensembl chr 2:53,189,790...53,203,821
JBrowse link
G Snx30 sorting nexin family member 30 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:74,683,902...74,813,013
Ensembl chr 5:74,684,015...74,792,631
JBrowse link
G Snx7 sorting nexin 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:205,843,164...205,927,737
Ensembl chr 2:205,842,837...205,927,763
JBrowse link
G Spata33 spermatogenesis associated 33 involved_in ISO (PMID:33087875) RGD PMID:33087875 NCBI chr19:51,246,514...51,258,894
Ensembl chr19:51,246,514...51,258,894
JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO
IBA
UniProtKB:Q9JK66 (PMID:20457763)
GO_REF:0000033
RGD
GO_Central
PMID:20457763 GO_REF:0000033 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO (PMID:33096711)
(PMID:25919711)
RGD PMID:25919711 PMID:33096711 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of ISO MGI:5319187 (PMID:22044588) RGD PMID:22044588 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029
Ensembl chr 6:159,927,139...159,946,029
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:1857263 (PMID:22044588)
Ensembl
RGD
PMID:22044588 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 involved_in ISO
IBA
(PMID:21855797)
GO_REF:0000033
RGD
GO_Central
PMID:21855797 GO_REF:0000033 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
JBrowse link
G Ulk2 unc-51 like autophagy activating kinase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:46,451,578...46,530,462
Ensembl chr10:46,454,030...46,530,407
JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:57,992,396...58,000,220
Ensembl chr 8:57,992,723...57,999,467
JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO MGI:5648633 (PMID:24949970) RGD PMID:24949970 NCBI chr10:4,927,799...5,123,749
Ensembl chr10:4,928,030...5,123,578
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19279012) RGD PMID:19279012 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Rnf41 ring finger protein 41 acts_upstream_of_or_within ISO MGI:1921624 (PMID:24949970) RGD PMID:24949970 NCBI chr 7:838,160...876,869
Ensembl chr 7:838,203...865,511
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO MGI:5319187 (PMID:22044588) RGD PMID:22044588 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029
Ensembl chr 6:159,927,139...159,946,029
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857263 (PMID:22044588)
Ensembl
RGD
PMID:22044588 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tspo translocator protein involved_in ISO (PMID:25470454) RGD PMID:25470454 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
G Usp30 ubiquitin specific peptidase 30 IMP RGD PMID:24896179 RGD:13208875 NCBI chr12:42,501,345...42,555,311
Ensembl chr12:42,501,348...42,555,616
JBrowse link
negative regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:24709290) RGD PMID:24709290 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Vps13c vacuolar protein sorting 13 homolog C involved_in ISO
ISS
(PMID:26942284)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:26942284 GO_REF:0000024 NCBI chr 8:68,478,366...68,651,893
Ensembl chr 8:68,478,395...68,651,895
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO (PMID:30217973) RGD PMID:30217973 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Atg7 autophagy related 7 IMP RGD PMID:37042059 RGD:407532700 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:22922758) RGD PMID:22922758 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519
JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in ISO (PMID:38340717) RGD PMID:38340717 NCBI chr18:30,085,093...30,098,105
Ensembl chr18:30,085,126...30,098,756
JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in ISO
IEA
ISS
(PMID:38340717)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:38340717 GO_REF:0000024 GO_REF:0000107 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573
JBrowse link
G Fbxo7 F-box protein 7 involved_in IMP
ISO
PMID:26310625
(PMID:26310625)
RGD PMID:26310625 PMID:26310625 RGD:11536096 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Htt huntingtin involved_in IEA
ISO
GO_REF:0000107
(PMID:25686248)
Ensembl
RGD
PMID:25686248 GO_REF:0000107 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO
GO_REF:0000024
(PMID:33510463)
(PMID:21102437)
(PMID:32939830)
UniProt
RGD
PMID:21102437 PMID:32939830 PMID:33510463 GO_REF:0000024 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:31919280) RGD PMID:31919280 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IMP
ISO
(PMID:26310625) RGD PMID:26310625 PMID:28608965 RGD:13432560 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:31618756)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:31618756 GO_REF:0000024 GO_REF:0000107 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:31618756)
UniProt
RGD
PMID:31618756 GO_REF:0000024 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in IMP PMID:29934347 UniProt PMID:29934347 RGD:405650300 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link
G Ube2a ubiquitin-conjugating enzyme E2A involved_in ISO (PMID:23685073) RGD PMID:23685073 NCBI chr  X:116,114,339...116,125,076
Ensembl chr  X:116,113,875...116,125,070
JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D involved_in ISO (PMID:29307555) RGD PMID:29307555 NCBI chr 5:156,830,509...157,055,895
Ensembl chr 5:156,830,512...157,055,891
JBrowse link
positive regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone involved_in ISO
IEA
(PMID:21855797)
GO_REF:0000107
RGD
Ensembl
PMID:21855797 GO_REF:0000107 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:23707074) RGD PMID:23707074 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO UniProtKB:Q9JK66 (PMID:20457763) RGD PMID:20457763 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Hk2 hexokinase 2 involved_in ISO (PMID:23962723) RGD PMID:23962723 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:30217973) RGD PMID:30217973 NCBI chr  X:20,873,795...21,001,378
Ensembl chr  X:20,873,795...21,001,262
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:24709290) RGD PMID:24709290 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:20871098) RGD PMID:20871098 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
(PMID:20457763), (PMID:20871098), (PMID:23212910)
GO_REF:0000107
RGD
Ensembl
PMID:20457763 PMID:20871098 PMID:23212910 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) RGD PMID:24270810 NCBI chr 4:11,305,122...11,311,963
Ensembl chr 4:11,305,110...11,311,962
JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO (PMID:32047033) RGD PMID:32047033 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31172217 RGD:329403053 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951
JBrowse link
G Bnip3l BCL2 interacting protein 3 like involved_in ISO UniProtKB:Q9Z2F7 (PMID:20200478) RGD PMID:20200478 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
JBrowse link
G Cttn cortactin involved_in IEA
ISO
GO_REF:0000107
(PMID:20457763)
Ensembl
RGD
PMID:20457763 GO_REF:0000107 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Dnm1l dynamin 1-like involved_in ISO UniProtKB:Q9BXM7 (PMID:19279012) RGD PMID:19279012 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:24912190) RGD PMID:24912190 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 involved_in ISO (PMID:28381481), (PMID:31908024) RGD PMID:28381481 PMID:31908024 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612
JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA
ISO
GO_REF:0000107
(PMID:24912190)
Ensembl
RGD
PMID:24912190 GO_REF:0000107 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISO (PMID:21355049) RGD PMID:21355049 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in ISO (PMID:24912190) RGD PMID:24912190 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr10:103,497,349...103,528,877
Ensembl chr10:103,497,349...103,528,877
JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO (PMID:25470454) RGD PMID:25470454 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 involved_in ISO UniProtKB:Q9JK66|UniProtKB:Q9Z2V5 (PMID:20457763) RGD PMID:20457763 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Mfn2 mitofusin 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:23620051)
Ensembl
RGD
PMID:23620051 GO_REF:0000107 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Optn optineurin involved_in ISO
IEA
(PMID:25294927)
GO_REF:0000107
RGD
Ensembl
PMID:25294927 GO_REF:0000107 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
(PMID:19029340)
GO_REF:0000107
RGD
Ensembl
PMID:19029340 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:22020285) RGD PMID:22020285 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 involved_in ISS
ISO
GO_REF:0000024
(PMID:37160114)
UniProt
RGD
PMID:37160114 GO_REF:0000024 NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379
Ensembl chr 3:7,409,688...7,436,379
Ensembl chr 6:7,409,688...7,436,379
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      process utilizing autophagic mechanism 560
        autophagy 560
          autophagy of mitochondrion 113
            mitophagy 95
              negative regulation of mitophagy + 9
              positive regulation of mitophagy + 26
              regulation of mitophagy + 47
              type 1 mitophagy 0
              type 2 mitophagy + 17
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        catabolic process 2871
          autophagy 560
            macroautophagy 325
              mitophagy 95
                negative regulation of mitophagy + 9
                positive regulation of mitophagy + 26
                regulation of mitophagy + 47
                type 1 mitophagy 0
                type 2 mitophagy + 17
paths to the root